SearcharxivSearch

arXiv subjects

Daniel Klein

Publications and source records attributed to Daniel Klein.

4 recordsLinked to original sources

Realizing Common Random Numbers: Event-Keyed Hashing for Causally Valid Stochastic Models

Agent-based models (ABMs) are widely used to estimate causal treatment effects via paired counterfactual simulation. A standard variance reduction technique is common random numbers (CRNs), which couples replicates across intervention scenarios by sharing the same random inputs. In practice, CRNs are implemented by reusing the same base seed, but this relies on a critical assumption: that the same draw index corresponds to the same modeled event across scenarios. Stateful pseudorandom number generators (PRNGs) violate this assumption whenever interventions alter the simulation's execution path, because any change in control flow shifts the draw index used for all downstream events. We argue that this execution-path-dependent draw indexing is not only a variance-reduction nuisance, but represents a fundamental mismatch between the scientific causal structure ABMs are intended to encode and the program-level causal structure induced by stateful PRNG implementations. Formalizing this through the lens of structural causal models (SCMs), we show that standard PRNG practices yield causally incoherent paired counterfactual comparisons even when the mechanistic specification is otherwise sound. We show that a remedy is to combine counter-based random number generators (e.g., Philox/Threefry) with event identifiers. This decouples random number generation from simulation execution order by making random draws explicit functions of the particular modeled event that called them, restoring the stable event-indexed exogenous structure assumed by SCMs.

stat.ME

Investigating Complex HPV Dynamics Using Emulation and History Matching

The study of transmission and progression of human papillomavirus (HPV) is crucial for understanding the incidence of cervical cancers, and has been identified as a priority worldwide. The complexity of the disease necessitates a detailed model of HPV transmission and its progression to cancer; to infer properties of the above we require a careful process that can match to imperfect or incomplete observational data. In this paper, we describe the HPVsim simulator to satisfy the former requirement; to satisfy the latter we couple this stochastic simulator to a process of emulation and history matching using the R package hmer. With these tools, we are able to obtain a comprehensive collection of parameter combinations that could give rise to observed cancer data, and explore the implications of the variability of these parameter sets as it relates to future health interventions.

stat.AP

FACTTRACK: Time-Aware World State Tracking in Story Outlines

While accurately detecting and correcting factual contradictions in language model outputs has become increasingly important as their capabilities improve, doing so is highly challenging. We propose a novel method, FACTTRACK, for tracking atomic facts and addressing factual contradictions. Crucially, FACTTRACK also maintains time-aware validity intervals for each fact, allowing for change over time. At a high level, FACTTRACK consists of a four-step pipeline to update a world state data structure for each new event: (1) decompose the event into directional atomic facts; (2) determine the validity interval of each atomic fact using the world state; (3) detect contradictions with existing facts in the world state; and finally (4) add new facts to the world state and update existing atomic facts. When we apply FACTTRACK to contradiction detection on structured story outlines, we find that FACTTRACK using LLaMA2-7B-Chat substantially outperforms a fair baseline using LLaMA2-7B-Chat, and achieves performance comparable to a GPT4 baseline. Moreover, when using GPT4, FACTTRACK significantly outperforms the GPT4 baseline.

cs.CL

Optimal Immunization Policy Using Dynamic Programming

Decisions in public health are almost always made in the context of uncertainty. Policy makers are responsible for making important decisions, faced with the daunting task of choosing from amongst many possible options. This task is called planning under uncertainty, and is particularly acute when addressing complex systems, such as issues of global health and development. Uncertainty leads to cautious or incorrect decisions that cost time, money, and human life. It is with this understanding that we pursue greater clarity on, and methods to address optimal policy making in health. Decision making under uncertainty is a challenging task, and all too often this uncertainty is averaged away to simplify results for policy makers. Our goal in this work is to implement dynamic programming which provides basis for compiling planning results into reactive strategies. We present here a description of an AI-based method and illustrate how this method can improve our ability to find an optimal vaccination strategy. We model the problem as a partially observable Markov decision process, POMDP and show how a re-active policy can be computed using dynamic programming. In this paper, we developed a framework for optimal health policy design in an uncertain dynamic setting. We apply a stochastic dynamic programming approach to identify the optimal time to change the health intervention policy and the value of decision relevant information for improving the impact of the policy.

cs.AI