SearcharxivSearch

arXiv subjects

Daniel W. Swartz

Publications and source records attributed to Daniel W. Swartz.

5 recordsLinked to original sources

Spatiotemporal noise stabilizes unbounded diversity in strongly-competitive communities

Classical ecological models predict that diverse communities should be unstable, presenting a central challenge to explaining the stable biodiversity seen in nature. We revisit this long-standing problem by extending the generalized Lotka-Volterra model to include both spatial structure and environmental fluctuations across space and time. We find that neither space nor environmental noise alone can resolve the tension between diversity and stability, but that together they permit arbitrarily many species to stably coexist in a sufficiently large system, despite strongly disordered competitive interactions. We analytically characterize the noise-induced transition to coexistence, showing that spatiotemporal noise drives power-law abundance fluctuations, leading to an anomalous scaling of moments known empirically as Taylor's law. At the metacommunity level, this manifests as an emergent sublinear self-inhibition that stabilizes diversity and renders the interaction disorder irrelevant in the high-diversity limit. Spatiotemporal noise thus provides a novel resolution to the diversity-stability paradox and a generic mechanism by which complex communities can persist.

q-bio.PE

New sector morphologies emerge from anisotropic colony growth

Competition during range expansions is of great interest from both practical and theoretical view points. Experimentally, range expansions are often studied in homogeneous Petri dishes, which lack spatial anisotropy that might be present in realistic populations. Here, we analyze a model of anisotropic growth, based on coupled Kardar-Parisi-Zhang and Fisher-Kolmogorov-Petrovsky-Piskunov equations that describe surface growth and lateral competition. Compared to a previous study of isotropic growth, anisotropy relaxes a constraint between parameters of the model. We completely characterize spatial patterns and invasion velocities in this generalized model. In particular, we find that strong anisotropy results in a distinct morphology of spatial invasion with a kink in the displaced strain ahead of the boundary between the strains. This morphology of the out-competed strain is similar to a shock wave and serves as a signature of anisotropic growth.

nlin.PS

How host mobility patterns shape antigenic escape during viral-immune co-evolution

Viruses like influenza have long coevolved with host immune systems, gradually shaping the evolutionary trajectory of these pathogens. Host immune systems develop immunity against circulating strains, which in turn avoid extinction by exploiting antigenic escape mutations that render new strains immune from existing antibodies in the host population. Infected hosts are also mobile, which can spread the virus to regions without developed host immunity, offering additional reservoirs for viral growth. While the effects of migration on long term stability have been investigated, we know little about how antigenic escape coupled with migration changes the survival and spread of emerging viruses. By considering the two processes on equal footing, we show that on short timescales an intermediate host mobility rate increases the survival probability of the virus through antigenic escape. We show that more strongly connected migratory networks decrease the survival probability of the virus. Using data from high traffic airports we argue that current human migration rates are beneficial for viral survival.

q-bio.PE

Competition on the edge of an expanding population

In growing populations, the fate of mutations depends on their competitive ability against the ancestor and their ability to colonize new territory. Here we present a theory that integrates both aspects of mutant fitness by coupling the classic description of one-dimensional competition (Fisher equation) to the minimal model of front shape (KPZ equation). We solved these equations and found three regimes, which are controlled solely by the expansion rates, solely by the competitive abilities, or by both. Collectively, our results provide a simple framework to study spatial competition.

q-bio.PE

Active gels, heavy tails, and the cytoskeleton

The eukaryotic cell's cytoskeleton is a prototypical example of an active material: objects embedded within it are driven by molecular motors acting on the cytoskeleton, leading to anomalous diffusive behavior. Experiments tracking the behavior of cell-attached objects have observed anomalous diffusion with a distribution of displacements that is non-Gaussian, with heavy tails. This has been attributed to "cytoquakes" or other spatially extended collective effects. We show, using simulations and analytical theory, that a simple continuum active gel model driven by fluctuating force dipoles naturally creates heavy power-law tails in cytoskeletal displacements. We predict that this power law exponent should depend on the geometry and dimensionality of where force dipoles are distributed through the cell; we find qualitatively different results for force dipoles in a 3D cytoskeleton and a quasi-two-dimensional cortex. We then discuss potential applications of this model both in cells and in synthetic active gels.

cond-mat.soft