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Daniele Durante

Publications and source records attributed to Daniele Durante.

At least 37 records · Page 2Linked to original sources

A Class of Conjugate Priors for Multinomial Probit Models which Includes the Multivariate Normal One

Multinomial probit models are routinely-implemented representations for learning how the class probabilities of categorical response data change with p observed predictors. Although several frequentist methods have been developed for estimation, inference and classification within such a class of models, Bayesian inference is still lagging behind. This is due to the apparent absence of a tractable class of conjugate priors, that may facilitate posterior inference on the multinomial probit coefficients. Such an issue has motivated increasing efforts toward the development of effective Markov chain Monte Carlo methods, but state-of-the-art solutions still face severe computational bottlenecks, especially in high dimensions. In this article, we show that the entire class of unified skew-normal (SUN) distributions is conjugate to several multinomial probit models. Leveraging this result and the SUN properties, we improve upon state-of-the-art solutions for posterior inference and classification both in terms of closed-form results for several functionals of interest, and also by developing novel computational methods relying either on independent and identically distributed samples from the exact posterior or on scalable and accurate variational approximations based on blocked partially-factorized representations. As illustrated in simulations and in a gastrointestinal lesions application, the magnitude of the improvements relative to current methods is particularly evident, in practice, when the focus is on high-dimensional studies.

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Possible evidence of p-modes in Cassini measurements of Saturn's gravity field

We analyze the range rate residual data from Cassini's gravity experiment that cannot be explained with a static, zonally symmetric gravity field. In this paper we reproduce the data using a simple forward model of gravity perturbations from normal modes. To do this, we stack data from multiple flybys to improve sensitivity. We find a partially degenerate set of normal mode energy spectra which successfully reproduce the unknown gravity signal from Cassini's flybys. Although there is no unique solution, we find that the models most likely to fit the data are dominated by gravitational contributions from p-modes between 500-700uHz. Because f-modes at lower frequencies have stronger gravity signals for a given amplitude, this result would suggest strong frequency dependence in normal mode excitation on Saturn. We predict peak amplitudes for p-modes on the order of several kilometers, at least an order of magnitude larger than the peak amplitudes inferred by Earth-based observations of Jupiter. The large p-mode amplitudes we predict on Saturn, if they are indeed present and steady state, would imply weak damping with a lower bound of Q>1e7 for these modes, consistent with theoretical predictions.

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A closed-form filter for binary time series

Non-Gaussian state-space models arise in several applications, and within this framework the binary time series setting provides a relevant example. However, unlike for Gaussian state-space models - where filtering, predictive and smoothing distributions are available in closed form - binary state-space models require approximations or sequential Monte Carlo strategies for inference and prediction. This is due to the apparent absence of conjugacy between the Gaussian states and the likelihood induced by the observation equation for the binary data. In this article we prove that the filtering, predictive and smoothing distributions in dynamic probit models with Gaussian state variables are, in fact, available and belong to a class of unified skew-normals (SUN) whose parameters can be updated recursively in time via analytical expressions. Also the key functionals of these distributions are, in principle, available, but their calculation requires the evaluation of multivariate Gaussian cumulative distribution functions. Leveraging SUN properties, we address this issue via novel Monte Carlo methods based on independent samples from the smoothing distribution, that can easily be adapted to the filtering and predictive case, thus improving state-of-the-art approximate and sequential Monte Carlo inference in small-to-moderate dimensional studies. Novel sequential Monte Carlo procedures that exploit the SUN properties are also developed to deal with online inference in high dimensions. Performance gains over competitors are outlined in a financial application.

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Keys of a Mission to Uranus or Neptune, the Closest Ice Giants

Uranus and Neptune are the archetypes of "ice giants", a class of planets that may be among the most common in the Galaxy. They hold the keys to understand the atmospheric dynamics and structure of planets with hydrogen atmospheres inside and outside the solar system; however, they are also the last unexplored planets of the Solar System. Their atmospheres are active and storms are believed to be fueled by methane condensation which is both extremely abundant and occurs at low optical depth. This means that mapping temperature and methane abundance as a function of position and depth will inform us on how convection organizes in an atmosphere with no surface and condensates that are heavier than the surrounding air, a general feature of giant planets. Owing to the spatial and temporal variability of these atmospheres, an orbiter is required. A probe would provide a reference atmospheric profile to lift ambiguities inherent to remote observations. It would also measure the abundances of noble gases which can be used to reconstruct the history of planet formation in the Solar System. Finally, mapping the planets' gravity and magnetic fields will be essential to constrain their global composition, atmospheric dynamics, structure and evolution. An exploration of Uranus or Neptune will be essential to understand these planets and will also be key to constrain and analyze data obtained at Jupiter, Saturn, and for numerous exoplanets with hydrogen atmospheres.

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Bayesian Testing for Exogenous Partition Structures in Stochastic Block Models

Network data often exhibit block structures characterized by clusters of nodes with similar patterns of edge formation. When such relational data are complemented by additional information on exogenous node partitions, these sources of knowledge are typically included in the model to supervise the cluster assignment mechanism or to improve inference on edge probabilities. Although these solutions are routinely implemented, there is a lack of formal approaches to test if a given external node partition is in line with the endogenous clustering structure encoding stochastic equivalence patterns among the nodes in the network. To fill this gap, we develop a formal Bayesian testing procedure which relies on the calculation of the Bayes factor between a stochastic block model with known grouping structure defined by the exogenous node partition and an infinite relational model that allows the endogenous clustering configurations to be unknown, random and fully revealed by the block-connectivity patterns in the network. A simple Markov chain Monte Carlo method for computing the Bayes factor and quantifying uncertainty in the endogenous groups is proposed. This routine is evaluated in simulations and in an application to study exogenous equivalence structures in brain networks of Alzheimer's patients.

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Bayesian cumulative shrinkage for infinite factorizations

There is a wide variety of models in which the dimension of the parameter space is unknown. For example, in factor analysis the number of latent factors is typically not known and has to be inferred from the observed data. Although classical shrinkage priors are useful in these contexts, increasing shrinkage priors can provide a more effective option, which progressively penalizes expansions with growing complexity. In this article we propose a novel increasing shrinkage prior, named the cumulative shrinkage process, for the parameters controlling the dimension in over-complete formulations. Our construction has broad applicability, simple interpretation, and is based on a sequence of spike and slab distributions which assign increasing mass to the spike as model complexity grows. Using factor analysis as an illustrative example, we show that this formulation has theoretical and practical advantages over current competitors, including an improved ability to recover the model dimension. An adaptive Markov chain Monte Carlo algorithm is proposed, and the methods are evaluated in simulation studies and applied to personality traits data.

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Tractable Bayesian Density Regression via Logit Stick-Breaking Priors

There is a growing interest in learning how the distribution of a response variable changes with a set of predictors. Bayesian nonparametric dependent mixture models provide a flexible approach to address this goal. However, several formulations require computationally demanding algorithms for posterior inference. Motivated by this issue, we study a class of predictor-dependent infinite mixture models, which relies on a simple representation of the stick-breaking prior via sequential logistic regressions. This formulation maintains the same desirable properties of popular predictor-dependent stick-breaking priors, and leverages a recent Pólya-gamma data augmentation to facilitate the implementation of several computational methods for posterior inference. These routines include Markov chain Monte Carlo via Gibbs sampling, expectation-maximization algorithms, and mean-field variational Bayes for scalable inference, thereby stimulating a wider implementation of Bayesian density regression by practitioners. The algorithms associated with these methods are presented in detail and tested in a toxicology study.

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Conjugate Bayes for probit regression via unified skew-normal distributions

Regression models for dichotomous data are ubiquitous in statistics. Besides being useful for inference on binary responses, these methods serve also as building blocks in more complex formulations, such as density regression, nonparametric classification and graphical models. Within the Bayesian framework, inference proceeds by updating the priors for the coefficients, typically set to be Gaussians, with the likelihood induced by probit or logit regressions for the responses. In this updating, the apparent absence of a tractable posterior has motivated a variety of computational methods, including Markov Chain Monte Carlo routines and algorithms which approximate the posterior. Despite being routinely implemented, Markov Chain Monte Carlo strategies face mixing or time-inefficiency issues in large p and small n studies, whereas approximate routines fail to capture the skewness typically observed in the posterior. This article proves that the posterior distribution for the probit coefficients has a unified skew-normal kernel, under Gaussian priors. Such a novel result allows efficient Bayesian inference for a wide class of applications, especially in large p and small-to-moderate n studies where state-of-the-art computational methods face notable issues. These advances are outlined in a genetic study, and further motivate the development of a wider class of conjugate priors for probit models along with methods to obtain independent and identically distributed samples from the unified skew-normal posterior.

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Determining the depth of Jupiter's Great Red Spot with Juno: a Slepian approach

One of Jupiter's most prominent atmospheric features, the Great Red Spot (GRS), has been observed for more than two centuries, yet little is known about its structure and dynamics below its observed cloud-level. While its anticyclonic vortex appearance suggests it might be a shallow weather-layer feature, the very long time span for which it was observed implies it is likely deeply rooted, otherwise it would have been sheared apart by Jupiter's turbulent atmosphere. Determining the GRS depth will shed light not only on the processes governing the GRS, but on the dynamics of Jupiter's atmosphere as a whole. The Juno mission single flyby over the GRS (PJ7) discovered using microwave radiometer measurements that the GRS is at least a couple hundred kilometers deep (Li et al. 2017). The next flybys over the GRS (PJ18 and PJ21), will allow high-precision gravity measurements that can be used to estimate how deep the GRS winds penetrate below the cloud-level. Here we propose a novel method to determine the depth of the GRS based on the new gravity measurements and a Slepian function approach that enables an effective representation of the wind-induced spatially-confined gravity signal, and an efficient determination of the GRS depth given the limited measurements. We show that with this method the gravity signal of the GRS should be detectable for wind depths deeper than 300 kilometers, with reasonable uncertainties that depend on depth (e.g., $\pm$100km for a GRS depth of 1000km).

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Saturn's deep atmospheric flows revealed by the Cassini Grand Finale gravity measurements

How deep do Saturn's zonal winds penetrate below the cloud-level has been a decades-long question, with important implications not only for the atmospheric dynamics, but also for the interior density structure, composition, magnetic field and core mass. The Cassini Grand Finale gravity experiment enables answering this question for the first time, with the premise that the planet's gravity harmonics are affected not only by the rigid body density structure but also by its flow field. Using a wide range of rigid body interior models and an adjoint based thermal wind balance, we calculate the optimal flow structure below the cloud-level and its depth. We find that with a wind profile, largely consistent with the observed winds, when extended to a depth of around 8,800 km, all the gravity harmonics measured by Cassini are explained. This solution is in agreement with considerations of angular momentum conservation, and is consistent with magnetohydrodynamics constraints.

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Conditionally conjugate mean-field variational Bayes for logistic models

Variational Bayes (VB) is a common strategy for approximate Bayesian inference, but simple methods are only available for specific classes of models including, in particular, representations having conditionally conjugate constructions within an exponential family. Models with logit components are an apparently notable exception to this class, due to the absence of conjugacy between the logistic likelihood and the Gaussian priors for the coefficients in the linear predictor. To facilitate approximate inference within this widely used class of models, Jaakkola and Jordan (2000) proposed a simple variational approach which relies on a family of tangent quadratic lower bounds of logistic log-likelihoods, thus restoring conjugacy between these approximate bounds and the Gaussian priors. This strategy is still implemented successfully, but less attempts have been made to formally understand the reasons underlying its excellent performance. To cover this key gap, we provide a formal connection between the above bound and a recent Pólya-gamma data augmentation for logistic regression. Such a result places the computational methods associated with the aforementioned bounds within the framework of variational inference for conditionally conjugate exponential family models, thereby allowing recent advances for this class to be inherited also by the methods relying on Jaakkola and Jordan (2000).

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Convex Mixture Regression for Quantitative Risk Assessment

There is wide interest in studying how the distribution of a continuous response changes with a predictor. We are motivated by environmental applications in which the predictor is the dose of an exposure and the response is a health outcome. A main focus in these studies is inference on dose levels associated with a given increase in risk relative to a baseline. Popular methods either dichotomize the continuous response or focus on modeling changes with the dose in the expectation of the outcome. Such choices may lead to information loss and provide inaccurate inference on dose-response relationships. We instead propose a Bayesian convex mixture regression model that allows the entire distribution of the health outcome to be unknown and changing with the dose. To balance flexibility and parsimony, we rely on a mixture model for the density at the extreme doses, and express the conditional density at each intermediate dose via a convex combination of these extremal densities. This representation generalizes classical dose-response models for quantitative outcomes, and provides a more parsimonious, but still powerful, formulation compared to nonparametric methods, thereby improving interpretability and efficiency in inference on risk functions. A Markov chain Monte Carlo algorithm for posterior inference is developed, and the benefits of our methods are outlined in simulations, along with a study on the impact of DDT exposure on gestational age.

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Bayesian inference on group differences in multivariate categorical data

Multivariate categorical data are common in many fields. We are motivated by election polls studies assessing evidence of changes in voters opinions with their candidates preferences in the 2016 United States Presidential primaries or caucuses. Similar goals arise routinely in several applications, but current literature lacks a general methodology which combines flexibility, efficiency, and tractability in testing for group differences in multivariate categorical data at different---potentially complex---scales. We address this goal by leveraging a Bayesian representation which factorizes the joint probability mass function for the group variable and the multivariate categorical data as the product of the marginal probabilities for the groups, and the conditional probability mass function of the multivariate categorical data, given the group membership. To enhance flexibility, we define the conditional probability mass function of the multivariate categorical data via a group-dependent mixture of tensor factorizations, thus facilitating dimensionality reduction and borrowing of information, while providing tractable procedures for computation, and accurate tests assessing global and local group differences. We compare our methods with popular competitors, and discuss improved performance in simulations and in American election polls studies.

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Bayesian semiparametric modelling of contraceptive behavior in India via sequential logistic regressions

Family planning has been characterized by highly different strategic programs in India, including method-specific contraceptive targets, coercive sterilization, and more recent target-free approaches. These major changes in family planning policies over time have motivated a considerable interest towards assessing the effectiveness of the different programs, while understanding which subsets of the population have not been properly addressed. Current studies consider specific aspects of the above policies, including, for example, the factors associated with the choice of alternative contraceptive methods other than sterilization, for women using contraceptives. Although these analyses produce relevant insights, they fail to provide a global overview of the different family planning policies, and the determinants underlying the contraceptive choices. Motivated by this consideration, we propose a Bayesian semiparametric model relying on a reparameterization of the multinomial probability mass function via a set of conditional Bernoulli choices. The sequential binary structure is defined to be consistent with the current family planning policies in India, and coherent with a reasonable process characterizing the contraceptive choices. This combination of flexible representations and careful reparameterizations allows a broader and interpretable overview of the different policies and contraceptive preferences in India, within a single model.

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Bayesian Network--Response Regression

There is increasing interest in learning how human brain networks vary as a function of a continuous trait, but flexible and efficient procedures to accomplish this goal are limited. We develop a Bayesian semiparametric model, which combines low-rank factorizations and flexible Gaussian process priors to learn changes in the conditional expectation of a network-valued random variable across the values of a continuous predictor, while including subject-specific random effects. The formulation leads to a general framework for inference on changes in brain network structures across human traits, facilitating borrowing of information and coherently characterizing uncertainty. We provide an efficient Gibbs sampler for posterior computation along with simple procedures for inference, prediction and goodness-of-fit assessments. The model is applied to learn how human brain networks vary across individuals with different intelligence scores. Results provide interesting insights on the association between intelligence and brain connectivity, while demonstrating good predictive performance.

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Bayesian Learning of Dynamic Multilayer Networks

A plethora of networks is being collected in a growing number of fields, including disease transmission, international relations, social interactions, and others. As data streams continue to grow, the complexity associated with these highly multidimensional connectivity data presents novel challenges. In this paper, we focus on the time-varying interconnections among a set of actors in multiple contexts, called layers. Current literature lacks flexible statistical models for dynamic multilayer networks, which can enhance quality in inference and prediction by efficiently borrowing information within each network, across time, and between layers. Motivated by this gap, we develop a Bayesian nonparametric model leveraging latent space representations. Our formulation characterizes the edge probabilities as a function of shared and layer-specific actors positions in a latent space, with these positions changing in time via Gaussian processes. This representation facilitates dimensionality reduction and incorporates different sources of information in the observed data. In addition, we obtain tractable procedures for posterior computation, inference, and prediction. We provide theoretical results on the flexibility of our model. Our methods are tested on simulations and infection studies monitoring dynamic face-to-face contacts among individuals in multiple days, where we perform better than current methods in inference and prediction.

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A note on the multiplicative gamma process

Adaptive dimensionality reduction in high-dimensional problems is a key topic in statistics. The multiplicative gamma process takes a relevant step in this direction, but improved studies on its properties are required to ease implementation. This note addresses such aim.

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