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Danilo Comminiello

Publications and source records attributed to Danilo Comminiello.

At least 19 recordsLinked to original sources

Trimodal Glioma Representation Alignment via Volumetric Contrastive Learning

Glioma grading and survival prediction require the integration of heterogeneous information collected at different spatial and biological scales. Histopathology describes tissue morphology, mRNA expression captures molecular activity, and magnetic resonance imaging provides a non-invasive view of tumor extent and radiological heterogeneity. Existing glioma prognosis models often combine only two of these sources, while their alignment objectives remain mostly pairwise. This paper introduces GLORIA, a novel trimodal framework for GLioma Omics - Radiology - hIstopathology Alignment. GLORIA processes whole-slide image regions, gene-expression profiles, and 3D MRI volumes through modality-specific encoders, projects them into a shared latent space, and aligns them with a Gramian contrastive loss that measures the volume spanned by the three modality embeddings. The aligned representations are fused through a cross-modal gating module and optimized jointly for three-class glioma grading and overall survival prediction. We evaluate GLORIA on a matched TCGA-GBM/LGG and BraTS21 cohort, comprising 132 patients with all three modalities. On the shared trimodal test set, GLORIA improves over the bimodal WSI-mRNA baseline in all the metrics considered.

eess.IV

GRAMformer: Any-Order Modality Interactions via Volumetric Multimodal Cross-Attention

Transformer-based multimodal models rely on attention mechanisms to integrate information across heterogeneous modalities. Despite their success, existing multimodal attention formulations compute their scores through collections of pairwise dot-product interactions or by concatenating all the modalities into the keys, even when multiple modalities should be jointly involved. As a consequence, current approaches either incur quadratic complexity in the number of modalities or fail to explicitly model interactions that depend on the joint configuration of multiple representations. In this work, we introduce the Volumetric Multimodal cross-Attention (VMA), a novel cross-attention mechanism in which attention scores are defined as a function of the joint geometry of a query and multiple modality-specific keys. VMA computes the volume spanned by query and key vectors across multiple modalities, capturing joint multimodal dependencies beyond pairwise similarity, enabling native modeling of any-order modality interactions. We integrate VMA into our novel multimodal transformer architecture, named GRAMformer, explicitly designed to integrate any number of modalities. We evaluate the proposed model on multimodal learning tasks, demonstrating improved effectiveness and efficiency.

cs.CV

Closing the gap in multimodal medical representation alignment

In multimodal learning, CLIP has emerged as the de-facto approach for mapping different modalities into a shared latent space by bringing semantically similar representations closer while pushing apart dissimilar ones. However, CLIP-based contrastive losses exhibit unintended behaviors that negatively impact true semantic alignment, leading to sparse and fragmented latent spaces. This phenomenon, known as the modality gap, has been partially mitigated for standard text and image pairs but remains unknown and unresolved in more complex multimodal settings, such as the medical domain. In this work, we study this phenomenon in the latter case, revealing that the modality gap is present also in medical alignment, and we propose a modality-agnostic framework that closes this gap, ensuring that semantically related representations are more aligned, regardless of their source modality. Our method enhances alignment between radiology images and clinical text, improving cross-modal retrieval and image captioning.

cs.CV

The IJCNN 2025 Review Process

The International Joint Conference on Neural Networks (IJCNN) is the premier international conference in the area of neural networks theory, analysis, and applications. The 2025 edition of the conference comprised 5,526 paper submissions, 7,877 active reviewers, 426 area chairs, 2,152 accepted papers, and more than 2,300 attendees. This represents a growth of about 100% in terms of submissions, 200% in terms of reviewers, and over 50% in terms of attendees as compared to the previous edition. In this paper, we describe several key aspects of the whole review process, including a strategy for ranking the scores provided by the reviewers by evaluating a score index and a calibrated version used experimentally to remove reviewer-specific bias from reviews.

cs.DL

Closing the Modality Gap Aligns Group-Wise Semantics

In multimodal learning, CLIP has been recognized as the \textit{de facto} method for learning a shared latent space across multiple modalities, placing similar representations close to each other and moving them away from dissimilar ones. Although CLIP-based losses effectively align modalities at the semantic level, the resulting latent spaces often remain only partially shared, revealing a structural mismatch known as the modality gap. While the necessity of addressing this phenomenon remains debated, particularly given its limited impact on instance-wise tasks (e.g., retrieval), we prove that its influence is instead strongly pronounced in group-level tasks (e.g., clustering). To support this claim, we introduce a novel method designed to consistently reduce this discrepancy in two-modal settings, with a straightforward extension to the general $n$-modal case. Through our extensive evaluation, we demonstrate our novel insight: while reducing the gap provides only marginal or inconsistent improvements in traditional instance-wise tasks, it significantly enhances group-wise tasks. These findings may reshape our understanding of the modality gap, highlighting its key role in improving performance on tasks requiring semantic grouping.

cs.LG

StereoSync: Spatially-Aware Stereo Audio Generation from Video

Although audio generation has been widely studied over recent years, video-aligned audio generation still remains a relatively unexplored frontier. To address this gap, we introduce StereoSync, a novel and efficient model designed to generate audio that is both temporally synchronized with a reference video and spatially aligned with its visual context. Moreover, StereoSync also achieves efficiency by leveraging pretrained foundation models, reducing the need for extensive training while maintaining high-quality synthesis. Unlike existing methods that primarily focus on temporal synchronization, StereoSync introduces a significant advancement by incorporating spatial awareness into video-aligned audio generation. Indeed, given an input video, our approach extracts spatial cues from depth maps and bounding boxes, using them as cross-attention conditioning in a diffusion-based audio generation model. Such an approach allows StereoSync to go beyond simple synchronization, producing stereo audio that dynamically adapts to the spatial structure and movement of a video scene. We evaluate StereoSync on Walking The Maps, a curated dataset comprising videos from video games that feature animated characters walking through diverse environments. Experimental results demonstrate the ability of StereoSync to achieve both temporal and spatial alignment, advancing the state of the art in video-to-audio generation and resulting in a significantly more immersive and realistic audio experience.

cs.SD

FoleyGRAM: Video-to-Audio Generation with GRAM-Aligned Multimodal Encoders

In this work, we present FoleyGRAM, a novel approach to video-to-audio generation that emphasizes semantic conditioning through the use of aligned multimodal encoders. Building on prior advancements in video-to-audio generation, FoleyGRAM leverages the Gramian Representation Alignment Measure (GRAM) to align embeddings across video, text, and audio modalities, enabling precise semantic control over the audio generation process. The core of FoleyGRAM is a diffusion-based audio synthesis model conditioned on GRAM-aligned embeddings and waveform envelopes, ensuring both semantic richness and temporal alignment with the corresponding input video. We evaluate FoleyGRAM on the Greatest Hits dataset, a standard benchmark for video-to-audio models. Our experiments demonstrate that aligning multimodal encoders using GRAM enhances the system's ability to semantically align generated audio with video content, advancing the state of the art in video-to-audio synthesis.

cs.SD

Controllable Audio-Visual Viewpoint Generation from 360{\deg} Spatial Information

The generation of sounding videos has seen significant advancements with the advent of diffusion models. However, existing methods often lack the fine-grained control needed to generate viewpoint-specific content from larger, immersive 360-degree environments. This limitation restricts the creation of audio-visual experiences that are aware of off-camera events. To the best of our knowledge, this is the first work to introduce a framework for controllable audio-visual generation, addressing this unexplored gap. Specifically, we propose a diffusion model by introducing a set of powerful conditioning signals derived from the full 360-degree space: a panoramic saliency map to identify regions of interest, a bounding-box-aware signed distance map to define the target viewpoint, and a descriptive caption of the entire scene. By integrating these controls, our model generates spatially-aware viewpoint videos and audios that are coherently influenced by the broader, unseen environmental context, introducing a strong controllability that is essential for realistic and immersive audio-visual generation. We show audiovisual examples proving the effectiveness of our framework.

cs.MM

Generative Models for Helmholtz Equation Solutions: A Dataset of Acoustic Materials

Accurate simulation of wave propagation in complex acoustic materials is crucial for applications in sound design, noise control, and material engineering. Traditional numerical solvers, such as finite element methods, are computationally expensive, especially when dealing with large-scale or real-time scenarios. In this work, we introduce a dataset of 31,000 acoustic materials, named HA30K, designed and simulated solving the Helmholtz equations. For each material, we provide the geometric configuration and the corresponding pressure field solution, enabling data-driven approaches to learn Helmholtz equation solutions. As a baseline, we explore a deep learning approach based on Stable Diffusion with ControlNet, a state-of-the-art model for image generation. Unlike classical solvers, our approach leverages GPU parallelization to process multiple simulations simultaneously, drastically reducing computation time. By representing solutions as images, we bypass the need for complex simulation software and explicit equation-solving. Additionally, the number of diffusion steps can be adjusted at inference time, balancing speed and quality. We aim to demonstrate that deep learning-based methods are particularly useful in early-stage research, where rapid exploration is more critical than absolute accuracy.

cs.LG

Semantic Compression via Multimodal Representation Learning

Multimodal representation learning produces high-dimensional embeddings that align diverse modalities in a shared latent space. While this enables strong generalization, it also introduces scalability challenges, both in terms of storage and downstream processing. A key open problem is how to achieve semantic compression, reducing the memory footprint of multimodal embeddings while preserving their ability to represent shared semantic content across modalities. In this paper, we prove a strong connection between reducing the modality gap, which is the residual separation of embeddings from different modalities, and the feasibility of post-training semantic compression. When the gap is sufficiently reduced, embeddings from different modalities but expressing the same semantics share a common portion of the space. Therefore, their centroid is a faithful representation of such a semantic concept. This enables replacing multiple embeddings with a single centroid, yielding significant memory savings. We propose a novel approach for semantic compression grounded on the latter intuition, operating directly on pretrained encoders. We demonstrate its effectiveness across diverse large-scale multimodal downstream tasks. Our results highlight that modality alignment is a key enabler for semantic compression, showing that the proposed approach achieves significant compression without sacrificing performance.

cs.LG

A TRIANGLE Enables Multimodal Alignment Beyond Cosine Similarity

Multimodal learning plays a pivotal role in advancing artificial intelligence systems by incorporating information from multiple modalities to build a more comprehensive representation. Despite its importance, current state-of-the-art models still suffer from severe limitations that prevent the successful development of a fully multimodal model. Such methods may not provide indicators that all the involved modalities are effectively aligned. As a result, some modalities may not be aligned, undermining the effectiveness of the model in downstream tasks where multiple modalities should provide additional information that the model fails to exploit. In this paper, we present TRIANGLE: TRI-modAl Neural Geometric LEarning, the novel proposed similarity measure that is directly computed in the higher-dimensional space spanned by the modality embeddings. TRIANGLE improves the joint alignment of three modalities via a triangle-area similarity, avoiding additional fusion layers or pairwise similarities. When incorporated in contrastive losses replacing cosine similarity, TRIANGLE significantly boosts the performance of multimodal modeling, while yielding interpretable alignment rationales. Extensive evaluation in three-modal tasks such as video-text and audio-text retrieval or audio-video classification, demonstrates that TRIANGLE achieves state-of-the-art results across different datasets improving the performance of cosine-based methods up to 9 points of Recall@1.

cs.LG

Training-Free Multimodal Guidance for Video to Audio Generation

Video-to-audio (V2A) generation aims to synthesize realistic and semantically aligned audio from silent videos, with potential applications in video editing, Foley sound design, and assistive multimedia. Although the excellent results, existing approaches either require costly joint training on large-scale paired datasets or rely on pairwise similarities that may fail to capture global multimodal coherence. In this work, we propose a novel training-free multimodal guidance mechanism for V2A diffusion that leverages the volume spanned by the modality embeddings to enforce unified alignment across video, audio, and text. The proposed multimodal diffusion guidance (MDG) provides a lightweight, plug-and-play control signal that can be applied on top of any pretrained audio diffusion model without retraining. Experiments on VGGSound and AudioCaps demonstrate that our MDG consistently improves perceptual quality and multimodal alignment compared to baselines, proving the effectiveness of a joint multimodal guidance for V2A.

cs.LG

Metadata, Wavelet, and Time Aware Diffusion Models for Satellite Image Super Resolution

The acquisition of high-resolution satellite imagery is often constrained by the spatial and temporal limitations of satellite sensors, as well as the high costs associated with frequent observations. These challenges hinder applications such as environmental monitoring, disaster response, and agricultural management, which require fine-grained and high-resolution data. In this paper, we propose MWT-Diff, an innovative framework for satellite image super-resolution (SR) that combines latent diffusion models with wavelet transforms to address these challenges. At the core of the framework is a novel metadata-, wavelet-, and time-aware encoder (MWT-Encoder), which generates embeddings that capture metadata attributes, multi-scale frequency information, and temporal relationships. The embedded feature representations steer the hierarchical diffusion dynamics, through which the model progressively reconstructs high-resolution satellite imagery from low-resolution inputs. This process preserves critical spatial characteristics including textural patterns, boundary discontinuities, and high-frequency spectral components essential for detailed remote sensing analysis. The comparative analysis of MWT-Diff across multiple datasets demonstrated favorable performance compared to recent approaches, as measured by standard perceptual quality metrics including FID and LPIPS. The code is available at https://github.com/LuigiSigillo/MWT-Diff

cs.CV

Latent Wavelet Diffusion For Ultra-High-Resolution Image Synthesis

High-resolution image synthesis remains a core challenge in generative modeling, particularly in balancing computational efficiency with the preservation of fine-grained visual detail. We present Latent Wavelet Diffusion (LWD), a lightweight training framework that significantly improves detail and texture fidelity in ultra-high-resolution (2K-4K) image synthesis. LWD introduces a novel, frequency-aware masking strategy derived from wavelet energy maps, which dynamically focuses the training process on detail-rich regions of the latent space. This is complemented by a scale-consistent VAE objective to ensure high spectral fidelity. The primary advantage of our approach is its efficiency: LWD requires no architectural modifications and adds zero additional cost during inference, making it a practical solution for scaling existing models. Across multiple strong baselines, LWD consistently improves perceptual quality and FID scores, demonstrating the power of signal-driven supervision as a principled and efficient path toward high-resolution generative modeling. The code is available at https://github.com/LuigiSigillo/LatentWaveletDiffusion

cs.CV

Quaternion Wavelet-Conditioned Diffusion Models for Image Super-Resolution

Image Super-Resolution is a fundamental problem in computer vision with broad applications spacing from medical imaging to satellite analysis. The ability to reconstruct high-resolution images from low-resolution inputs is crucial for enhancing downstream tasks such as object detection and segmentation. While deep learning has significantly advanced SR, achieving high-quality reconstructions with fine-grained details and realistic textures remains challenging, particularly at high upscaling factors. Recent approaches leveraging diffusion models have demonstrated promising results, yet they often struggle to balance perceptual quality with structural fidelity. In this work, we introduce ResQu a novel SR framework that integrates a quaternion wavelet preprocessing framework with latent diffusion models, incorporating a new quaternion wavelet- and time-aware encoder. Unlike prior methods that simply apply wavelet transforms within diffusion models, our approach enhances the conditioning process by exploiting quaternion wavelet embeddings, which are dynamically integrated at different stages of denoising. Furthermore, we also leverage the generative priors of foundation models such as Stable Diffusion. Extensive experiments on domain-specific datasets demonstrate that our method achieves outstanding SR results, outperforming in many cases existing approaches in perceptual quality and standard evaluation metrics. The code is available at https://www.github.com/Fascetta/ResQu

cs.CV

Beyond Answers: How LLMs Can Pursue Strategic Thinking in Education

Artificial Intelligence (AI) holds transformative potential in education, enabling personalized learning, enhancing inclusivity, and encouraging creativity and curiosity. In this paper, we explore how Large Language Models (LLMs) can act as both patient tutors and collaborative partners to enhance education delivery. As tutors, LLMs personalize learning by offering step-by-step explanations and addressing individual needs, making education more inclusive for students with diverse backgrounds or abilities. As collaborators, they expand students' horizons, supporting them in tackling complex, real-world problems and co-creating innovative projects. However, to fully realize these benefits, LLMs must be leveraged not as tools for providing direct solutions but rather to guide students in developing resolving strategies and finding learning paths together. Therefore, a strong emphasis should be placed on educating students and teachers on the successful use of LLMs to ensure their effective integration into classrooms. Through practical examples and real-world case studies, this paper illustrates how LLMs can make education more inclusive and engaging while empowering students to reach their full potential.

cs.CY

FolAI: Synchronized Foley Sound Generation with Semantic and Temporal Alignment

Traditional sound design workflows rely on manual alignment of audio events to visual cues, as in Foley sound design, where everyday actions like footsteps or object interactions are recreated to match the on-screen motion. This process is time-consuming, difficult to scale, and lacks automation tools that preserve creative intent. Despite recent advances in vision-to-audio generation, producing temporally coherent and semantically controllable sound effects from video remains a major challenge. To address these limitations, we introduce FolAI, a two-stage generative framework that decouples the when and the what of sound synthesis, i.e., the temporal structure extraction and the semantically guided generation, respectively. In the first stage, we estimate a smooth control signal from the video that captures the motion intensity and rhythmic structure over time, serving as a temporal scaffold for the audio. In the second stage, a diffusion-based generative model produces sound effects conditioned both on this temporal envelope and on high-level semantic embeddings, provided by the user, that define the desired auditory content (e.g., material or action type). This modular design enables precise control over both timing and timbre, streamlining repetitive tasks while preserving creative flexibility in professional Foley workflows. Results on diverse visual contexts, such as footstep generation and action-specific sonorization, demonstrate that our model reliably produces audio that is temporally aligned with visual motion, semantically consistent with user intent, and perceptually realistic. These findings highlight the potential of FolAI as a controllable and modular solution for scalable, high-quality Foley sound synthesis in professional and interactive settings. Supplementary materials are accessible on our dedicated demo page at https://ispamm.github.io/FolAI.

cs.SD

Gramian Multimodal Representation Learning and Alignment

Human perception integrates multiple modalities, such as vision, hearing, and language, into a unified understanding of the surrounding reality. While recent multimodal models have achieved significant progress by aligning pairs of modalities via contrastive learning, their solutions are unsuitable when scaling to multiple modalities. These models typically align each modality to a designated anchor without ensuring the alignment of all modalities with each other, leading to suboptimal performance in tasks requiring a joint understanding of multiple modalities. In this paper, we structurally rethink the pairwise conventional approach to multimodal learning and we present the novel Gramian Representation Alignment Measure (GRAM), which overcomes the above-mentioned limitations. GRAM learns and then aligns $n$ modalities directly in the higher-dimensional space in which modality embeddings lie by minimizing the Gramian volume of the $k$-dimensional parallelotope spanned by the modality vectors, ensuring the geometric alignment of all modalities simultaneously. GRAM can replace cosine similarity in any downstream method, holding for 2 to $n$ modalities and providing more meaningful alignment with respect to previous similarity measures. The novel GRAM-based contrastive loss function enhances the alignment of multimodal models in the higher-dimensional embedding space, leading to new state-of-the-art performance in downstream tasks such as video-audio-text retrieval and audio-video classification. The project page, the code, and the pretrained models are available at https://ispamm.github.io/GRAM/.

cs.CV