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Danko Dimchev Georgiev

Publications and source records attributed to Danko Dimchev Georgiev.

3 recordsLinked to original sources

The causal consciousness: presynaptic beta-neurexin promotes neuromediator release via vibrational multidimensional tunneling

Epiphenomenalism is shown to be absurd because the development of consciousness must be explainable through natural selection. A detailed neuromolecular basis of the neuromediator release is given and it is stressed on the possible key point where the quantum mind could act, namely presynaptic scaffold protein dynamics and detachment of the calcium sensor v-SNARE synaptotagmin-1. The beta-neurexin molecules are tuned via fast propagating solitons by the quantum coherent microtubule network so that the beta-neurexin molecule thermal vibrations could promote or suppress conformational changes via vibrational multidimensional tunneling, which drives synaptotagmin-1 detachment from the SNARE complex under calcium ion binding. Following the synaptotagmin-1 detachment membrane fusion takes place in SNARE dependent fashion and the presynaptic vesicle spills neuromediator in the synaptic cleft. Thus the quantum transfer of information causally affects the neuromediator release.

quant-ph

Impairment of consciousness in Alzheimer's disease: the amyloid water-filled nanotubes manifest quantum optical coherence interfering with the normal QBD?

Recent discovery by Perutz et al. of the physical structure of the amyloid that accumulates in neurons in certain neurodegenerative diseases like Alzheimer's disease or Huntington's disease, suggests novel mechanism of consciousness impairment, different from the neuronal loss, which is the end stage of the pathogenic process. Amyloid is shown to be water-filled nanotubes made of polymerized pathologically-changed proteins. It is hypothesized that the water inside the new-formed nanotubes can manifest optical coherent laser-like excitations and superradiance similarly to the processes taking part in the normal brain microtubules as shown by Jibu et al. The interfering with the macroscopic quantum effects within the normal microtubules can lead to impairment of conscious experience. Experimental data in favor of quantum theory of consciousness can be obtained from the research of the amyloid nanotubes.

quant-ph