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David A. Bader

Publications and source records attributed to David A. Bader.

21 records · Page 2Linked to original sources

Exemplar or Matching: Modeling DCJ Problems with Unequal Content Genome Data

The edit distance under the DCJ model can be computed in linear time for genomes with equal content or with Indels. But it becomes NP-Hard in the presence of duplications, a problem largely unsolved especially when Indels are considered. In this paper, we compare two mainstream methods to deal with duplications and associate them with Indels: one by deletion, namely DCJ-Indel-Exemplar distance; versus the other by gene matching, namely DCJ-Indel-Matching distance. We design branch-and-bound algorithms with set of optimization methods to compute exact distances for both. Furthermore, median problems are discussed in alignment with both of these distance methods, which are to find a median genome that minimizes distances between itself and three given genomes. Lin-Kernighan (LK) heuristic is leveraged and powered up by sub-graph decomposition and search space reduction technologies to handle median computation. A wide range of experiments are conducted on synthetic data sets and real data sets to show pros and cons of these two distance metrics per se, as well as putting them in the median computation scenario.

cs.DS↗

Spectral Partitioning with Blends of Eigenvectors

Many common methods for data analysis rely on linear algebra. We provide new results connecting data analysis error to numerical accuracy, which leads to the first meaningful stopping criterion for two way spectral partitioning. More generally, we provide pointwise convergence guarantees so that blends (linear combinations) of eigenvectors can be employed to solve data analysis problems with confidence in their accuracy. We demonstrate this theory on an accessible model problem, the Ring of Cliques, by deriving the relevant eigenpairs and comparing the predicted results to numerical solutions. These results bridge the gap between linear algebra based data analysis methods and the convergence theory of iterative approximation methods.

math.NA↗

On the random access performance of Cell Broadband Engine with graph analysis application

The Cell Broad Engine (BE) Processor has unique memory access architecture besides its powerful computing engines. Many computing-intensive applications have been ported to Cell/BE successfully. But memory-intensive applications are rarely investigated except for several micro benchmarks. Since Cell/BE has powerful software visible DMA engine, this paper studies on whether Cell/BE is suit for applica- tions with large amount of random memory accesses. Two benchmarks, GUPS and SSCA#2, are used. The latter is a rather complex one that in representative of real world graph analysis applications. We find both benchmarks have good performance on Cell/BE based IBM QS20/22. Com- pared with 2 conventional multi-processor systems with the same core/thread number, GUPS is about 40-80% fast and SSCA#2 about 17-30% fast. The dynamic load balanc- ing and software pipeline for optimizing SSCA#2 are intro- duced. Based on the experiment, the potential of Cell/BE for random access is analyzed in detail as well as its limita- tions of memory controller, atomic engine and TLB manage- ment.Our research shows although more programming effort are needed, Cell/BE has the potencial for irregular memory access applications.

cs.CE↗