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David Barnhill

Publications and source records attributed to David Barnhill.

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Methodological considerations for semialgebraic hypothesis testing with incomplete U-statistics

Recently, Sturma, Drton, and Leung proposed a general-purpose stochastic method for hypothesis testing in models defined by polynomial equality and inequality constraints. Notably, the method remains theoretically valid even near irregular points, such as singularities and boundaries, where traditional testing approaches often break down. In this paper, we evaluate its practical performance on a collection of biologically motivated models from phylogenetics. While the method performs remarkably well across different settings, we catalogue a number of issues that should be considered for effective application.

q-bio.PE

LikelihoodGeometry: Macaulay2 Package

This note introduces the $\texttt{LikelihoodGeometry}$ package for the computer algebra system $\textit{Macaulay2}$. This package gives tools to construct the likelihood correspondence of a discrete algebraic statistical model, a variety that that ties together data and their maximum likelihood estimators. This includes methods for constructing and combining popular statistical models and calculating their ML-degree.

stat.CO

Tropical Fermat-Weber Polytropes

We study the geometry of tropical Fermat--Weber points, that is, optimal solutions to a location problem over a projective space using a dissimilarity measure derived from the tropical metric. It is well-known that for a given sample, such points are not necessarily unique, and we show that the set of all possible Fermat--Weber points forms a polytrope. This follows from the fact that our location problem turns out to be dual to a particular minimum-cost flow problem, and we describe the polytrope of optimal locations in the terminology of tropical geometry. We also provide a simple gradient descent algorithm that converges to the Fermat--Weber polytrope.

math.CO

Likelihood Correspondence of Toric Statistical Models

Maximum likelihood estimation (MLE) is a fundamental problem in statistics. Characteristics of the MLE problem for discrete algebraic statistical models are reflected in the geometry of the $\textit{likelihood correspondence}$, a variety that ties together data and their maximum likelihood estimators. We construct this ideal for the large class of toric models and find a Gr\"{o}bner basis in the case of complete and joint independence models arising from multi-way contingency tables. All of our constructions are implemented in $\textit{Macaulay2}$ in a package $\texttt{LikelihoodGeometry}$ along with other tools of use in algebraic statistics. We end with an experimental section using these implementations on several interesting examples.

math.ST

Tropical Geometric Tools for Machine Learning: the TML package

In the last decade, developments in tropical geometry have provided a number of uses directly applicable to problems in statistical learning. The TML package is the first R package which contains a comprehensive set of tools and methods used for basic computations related to tropical convexity, visualization of tropically convex sets, as well as supervised and unsupervised learning models using the tropical metric under the max-plus algebra over the tropical projective torus. Primarily, the TML package employs a Hit and Run Markov chain Monte Carlo sampler in conjunction with the tropical metric as its main tool for statistical inference. In addition to basic computation and various applications of the tropical HAR sampler, we also focus on several supervised and unsupervised methods incorporated in the TML package including tropical principal component analysis, tropical logistic regression and tropical kernel density estimation.

stat.ML

Maximum Inscribed and Minimum Enclosing Tropical Balls of Tropical Polytopes and Applications to Volume Estimation and Uniform Sampling

We consider a minimum enclosing and maximum inscribed tropical balls for any given tropical polytope over the tropical projective torus in terms of the tropical metric with the max-plus algebra. We show that we can obtain such tropical balls via linear programming. Then we apply minimum enclosing and maximum inscribed tropical balls of any given tropical polytope to estimate the volume of and sample uniformly from the tropical polytope.

math.CO

Hit and Run Sampling from Tropically Convex Sets

In this paper we propose Hit and Run (HAR) sampling from a tropically convex set. The key ingredient of HAR sampling from a tropically convex set is sampling uniformly from a tropical line segment over the tropical projective torus, which runs linearly in its computational time complexity. We show that this HAR sampling method samples uniformly from a tropical polytope which is the smallest tropical convex set of finitely many vertices. Finally, we apply this novel method to any given distribution using Metropolis-Hasting filtering over a tropical polytope.

math.CO

Tropical Density Estimation of Phylogenetic Trees

Much evidence from biological theory and empirical data indicates that, gene tree, phylogenetic trees reconstructed from different genes (loci), do not have to have exactly the same tree topologies. Such incongruence between gene trees might be caused by some ``unusual'' evolutionary events, such as meiotic sexual recombination in eukaryotes or horizontal transfers of genetic material in prokaryotes. However, most of gene trees are constrained by the tree topology of its species tree, that is, the phylogenetic tree of a given species following their evolutionary history. In order to discover ``outlying'' gene trees which do not follow the ``main distribution(s)'' of trees, we propose to apply the ``tropical metric'' with the max-plus algebra from tropical geometry to a non-parametric estimation of gene trees over the space of phylogenetic trees. In this research we apply the ``tropical metric,'' a well-defined metric over the space of phylogenetic trees under the max-plus algebra, to non-parametric estimation of gene trees distribution over the tree space. Kernel density estimator (KDE) is one of the most popular non-parametric estimation of a distribution from a given sample, and we propose an analogue of the classical KDE in the setting of tropical geometry with the tropical metric which measures the length of an intrinsic geodesic between trees over the tree space. We estimate the probability of an observed tree by empirical frequencies of nearby trees, with the level of influence determined by the tropical metric. Then, with simulated data generated from the multispecies coalescent model, we show that the non-parametric estimation of gene tree distribution using the tropical metric performs better than one using the Billera-Holmes-Vogtmann (BHV) metric developed by Weyenberg et al. in terms of computational times and accuracy. We then apply it to Apicomplexa data.

q-bio.PE

Connecting Tables with Allowing Negative Cell Counts

It is well-known that computing a Markov basis for a discrete loglinear model is very hard in general. Thus, we focus on connecting tables in a fiber via a subset of a Markov basis and in this paper, we consider connecting tables if we allow cell counts in each tale to be $-1$. In this paper we show that if a subset of a Markov basis connects all tables in the fiber which contains a table with all ones, then moves in this subset connect tables in the fiber if we allow cell counts to be $-1$. In addition, we show that in some cases under the no-three-way interaction model, we can connect tables by all basic moves of $2 \times 2 \times 2$ minors with allowing $X_{ijk} \geq -1$. We then apply this Markov Chain Monte Carlo (MCMC) scheme to an empirical data on Naval officer and enlisted population. Our computational experiments show it works well and we end with the conjecture on the no-three-way interaction model.

stat.ME