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David Chen

Publications and source records attributed to David Chen.

At least 19 recordsLinked to original sources

Deep adaptive design with an evidential bias criterion

Bayesian optimal experimental design (BOED) aims to collect informative data by optimizing an expected utility reflecting the goals of an experiment. However, this optimization is computationally challenging for common utilities and complex models. This is especially so for sequential or adaptive designs, where design and data collection alternate, so that feedback from already observed data must be taken into account. Most existing BOED research employs information gain as the utility, leading to the expected information gain (EIG) criterion. While EIG is widely useful, it may not always adequately reflect experimental goals. EIG can be viewed as rewarding experiments that produce large positive evidence for the truth on average, but it does not directly control the risk of an experiment producing misleading evidence. Here we consider an alternative criterion, which we call bias against (BA), that prioritizes such control. To address computational challenges when applying this criterion for adaptive design, we consider a policy-based deep adaptive design framework, which has previously been used for the EIG criterion. Minimizing a tractable upper bound on the BA objective is equivalent to maximizing a variance-penalized EIG criterion, and we optimize the latter by approximating it by Monte Carlo and learning design policies using stochastic gradient methods. The differences between BA and EIG designs are demonstrated in several examples including the adaptive design of a complex discrete choice experiment.

stat.ME

Local permutation tests for conditional independence: an adaptive binning perspective

In this work, we study the problem of testing conditional independence between random variables $X$ and $Y$ given a confounder $Z$. The local permutation test (LPT) offers a principled approach to this problem by partitioning the $Z$-space into pre-specified bins, and permuting the $X$ and $Y$ data within each bin, to assess the significance of an observed test statistic. However, when the partitions are pre-fixed, the resulting partition can be poorly balanced, as some bins may contain most of the samples while others contain only a few. This motivates the use of data-adaptive binning strategies, such as equisized bins with a fixed (typically small) number of points. We study this natural and practically important extension of LPT, providing finite-sample bounds on the Type I error for an arbitrary test statistic, providing stronger validity results than previously known. We also show that LPT attains power comparable to the oracle likelihood ratio tests derived from the Neyman-Pearson lemma. Within a linear confounder model class, we further analyze the effect of bin size and demonstrate that constant bin sizes can match the performance of partitions with growing bin-size. These results, further supported by extensive numerical simulations, position the proposed data-adaptive strategy as both practically implementable and statistically efficient.

stat.ME

CIWI-CKT: Chaos-Informed Wave Interference Feature Fusion and Cross-City Knowledge Transfer for Traffic Flow Forecasting

Accurate traffic flow prediction remains challenging in cross-city, data-scarce scenarios where limited historical data hinders model generalisation. The chaotic nature of traffic dynamics, complex spatio-temporal dependencies, and heterogeneous urban networks complicate few-shot learning across cities. Existing deep learning approaches either treat traffic as purely deterministic or lack mechanisms to model wave-like interference patterns essential for cross-regime traffic dynamics. To address these limitations, this paper proposes CIWI-CKT, a novel Chaos-Informed Wave Interference Feature Fusion framework with Cross-City Knowledge Transfer. Our framework introduces three core innovations: chaos-informed wave generation that extracts measurable chaos invariants and models traffic as adaptive wave components; meta-interference processing that captures wave interactions between support and query regimes while producing a predictability score for confidence estimation; and chaos-aware meta-learning that enables efficient cross-city knowledge transfer while preserving chaotic characteristics. We establish theoretical guarantees including chaos-to-wave stability, wave-induced dimension reduction, and meta-learning generalisation bounds. Extensive experiments on four real-world traffic datasets demonstrate that CIWI-CKT significantly outperforms state-of-the-art spatio-temporal graph learning, transfer learning, prompt-based, and few-shot methods, improving prediction accuracy while substantially reducing required training data.

cs.LG

Neuromorphic Graph Anomaly Detection via Adaptive STDP and Spiking Graph Neural Networks

Anomaly detection in dynamic networks is critical for applications from cybersecurity to industrial monitoring, yet existing methods face challenges in energy efficiency, temporal precision, and adaptability. This paper introduces ASTDP-GAD, a novel Adaptive Spiking Temporal Dynamics Plasticity framework for Graph Anomaly Detection that integrates spiking graph neural networks with STDP learning for energy-efficient neuromorphic detection in dynamic networks. Our framework unifies spiking neural computation, STDP learning, and graph-based anomaly detection through the following key innovations: temporal spike graph encoding with adaptive Leaky Integrate-and-Fire (LIF) dynamics; LIF-based graph attention with lateral inhibition; event-driven hypergraph memory with STDP-inspired prototype updates; spike rate contrast pooling based on spiking irregularity; adaptive STDP layers capturing causal temporal relationships; and multi-scale temporal convolution with multi-factor anomaly fusion. Theoretical analysis provides rigorous guarantees: spike encoding preserves input information with resolution scaling linearly in simulation steps and hidden dimension; LIFGAT approximates any continuous attention function; hypergraph memory converges to optimal prototypes; contrast pooling achieves provable anomaly selection bounds; STDP learning converges stably; and multi-factor fusion produces calibrated scores with up to $5\times$ variance reduction. Extensive experiments on nine datasets on both dynamic and static graphs demonstrate superior anomaly detection accuracy while maintaining biological plausibility and energy efficiency for neuromorphic deployment.

cs.NE

Performance Optimization in Stream Processing Systems: Experiment-Driven Configuration Tuning for Kafka Streams

Configuring stream processing systems for efficient performance, especially in cloud-native deployments, is a challenging and largely manual task. We present an experiment-driven approach for automated configuration optimization that combines three phases: Latin Hypercube Sampling for initial exploration, Simulated Annealing for guided stochastic search, and Hill Climbing for local refinement. The workflow is integrated with the cloud-native Theodolite benchmarking framework, enabling automated experiment orchestration on Kubernetes and early termination of underperforming configurations. In an experimental evaluation with Kafka Streams and a Kubernetes-based cloud testbed, our approach identifies configurations that improve throughput by up to 23% over the default. The results indicate that Latin Hypercube Sampling with early termination and Simulated Annealing are particularly effective in navigating the configuration space, whereas additional fine-tuning via Hill Climbing yields limited benefits.

cs.PF

GRAFNet: Multiscale Retinal Processing via Guided Cortical Attention Feedback for Enhancing Medical Image Polyp Segmentation

Accurate polyp segmentation in colonoscopy is essential for cancer prevention but remains challenging due to: (1) high morphological variability (from flat to protruding lesions), (2) strong visual similarity to normal structures such as folds and vessels, and (3) the need for robust multi-scale detection. Existing deep learning approaches suffer from unidirectional processing, weak multi-scale fusion, and the absence of anatomical constraints, often leading to false positives (over-segmentation of normal structures) and false negatives (missed subtle flat lesions). We propose GRAFNet, a biologically inspired architecture that emulates the hierarchical organisation of the human visual system. GRAFNet integrates three key modules: (1) a Guided Asymmetric Attention Module (GAAM) that mimics orientation-tuned cortical neurones to emphasise polyp boundaries, (2) a MultiScale Retinal Module (MSRM) that replicates retinal ganglion cell pathways for parallel multi-feature analysis, and (3) a Guided Cortical Attention Feedback Module (GCAFM) that applies predictive coding for iterative refinement. These are unified in a Polyp Encoder-Decoder Module (PEDM) that enforces spatial-semantic consistency via resolution-adaptive feedback. Extensive experiments on five public benchmarks (Kvasir-SEG, CVC-300, CVC-ColonDB, CVC-Clinic, and PolypGen) demonstrate consistent state-of-the-art performance, with 3-8% Dice improvements and 10-20% higher generalisation over leading methods, while offering interpretable decision pathways. This work establishes a paradigm in which neural computation principles bridge the gap between AI accuracy and clinically trustworthy reasoning. Code is available at https://github.com/afofanah/GRAFNet.

cs.CV

CAST-CKT: Chaos-Aware Spatio-Temporal and Cross-City Knowledge Transfer for Traffic Flow Prediction

Traffic prediction in data-scarce, cross-city settings is challenging due to complex nonlinear dynamics and domain shifts. Existing methods often fail to capture traffic's inherent chaotic nature for effective few-shot learning. We propose CAST-CKT, a novel Chaos-Aware Spatio-Temporal and Cross-City Knowledge Transfer framework. It employs an efficient chaotic analyser to quantify traffic predictability regimes, driving several key innovations: chaos-aware attention for regime-adaptive temporal modelling; adaptive topology learning for dynamic spatial dependencies; and chaotic consistency-based cross-city alignment for knowledge transfer. The framework also provides horizon-specific predictions with uncertainty quantification. Theoretical analysis shows improved generalisation bounds. Extensive experiments on four benchmarks in cross-city few-shot settings show CAST-CKT outperforms state-of-the-art methods by significant margins in MAE and RMSE, while offering interpretable regime analysis. Code is available at https://github.com/afofanah/CAST-CKT.

cs.AI

Enhancing Imbalanced Node Classification via Curriculum-Guided Feature Learning and Three-Stage Attention Network

Imbalanced node classification in graph neural networks (GNNs) happens when some labels are much more common than others, which causes the model to learn unfairly and perform badly on the less common classes. To solve this problem, we propose a Curriculum-Guided Feature Learning and Three-Stage Attention Network (CL3AN-GNN), a learning network that uses a three-step attention system (Engage, Enact, Embed) similar to how humans learn. The model begins by engaging with structurally simpler features, defined as (1) local neighbourhood patterns (1-hop), (2) low-degree node attributes, and (3) class-separable node pairs identified via initial graph convolutional networks and graph attention networks (GCN and GAT) embeddings. This foundation enables stable early learning despite label skew. The Enact stage then addresses complicated aspects: (1) connections that require multiple steps, (2) edges that connect different types of nodes, and (3) nodes at the edges of minority classes by using adjustable attention weights. Finally, Embed consolidates these features via iterative message passing and curriculum-aligned loss weighting. We evaluate CL3AN-GNN on eight Open Graph Benchmark datasets spanning social, biological, and citation networks. Experiments show consistent improvements across all datasets in accuracy, F1-score, and AUC over recent state-of-the-art methods. The model's step-by-step method works well with different types of graph datasets, showing quicker results than training everything at once, better performance on new, imbalanced graphs, and clear explanations of each step using gradient stability and attention correlation learning curves. This work provides both a theoretically grounded framework for curriculum learning in GNNs and practical evidence of its effectiveness against imbalances, validated through metrics, convergence speeds, and generalisation tests.

cs.LG

PIMPC-GNN: Physics-Informed Multi-Phase Consensus Learning for Enhancing Imbalanced Node Classification in Graph Neural Networks

Graph neural networks (GNNs) often struggle in class-imbalanced settings, where minority classes are under-represented and predictions are biased toward majorities. We propose \textbf{PIMPC-GNN}, a physics-informed multi-phase consensus framework for imbalanced node classification. Our method integrates three complementary dynamics: (i) thermodynamic diffusion, which spreads minority labels to capture long-range dependencies, (ii) Kuramoto synchronisation, which aligns minority nodes through oscillatory consensus, and (iii) spectral embedding, which separates classes via structural regularisation. These perspectives are combined through class-adaptive ensemble weighting and trained with an imbalance-aware loss that couples balanced cross-entropy with physics-based constraints. Across five benchmark datasets and imbalance ratios from 5-100, PIMPC-GNN outperforms 16 state-of-the-art baselines, achieving notable gains in minority-class recall (up to +12.7\%) and balanced accuracy (up to +8.3\%). Beyond empirical improvements, the framework also provides interpretable insights into consensus dynamics in graph learning. The code is available at \texttt{https://github.com/afofanah/PIMPC-GNN}.

cs.LG

PIMCST: Physics-Informed Multi-Phase Consensus and Spatio-Temporal Few-Shot Learning for Traffic Flow Forecasting

Accurate traffic flow prediction remains a fundamental challenge in intelligent transportation systems, particularly in cross-domain, data-scarce scenarios where limited historical data hinders model training and generalisation. The complex spatio-temporal dependencies and nonlinear dynamics of urban mobility networks further complicate few-shot learning across different cities. This paper proposes MCPST, a novel Multi-phase Consensus Spatio-Temporal framework for few-shot traffic forecasting that reconceptualises traffic prediction as a multi-phase consensus learning problem. Our framework introduces three core innovations: (1) a multi-phase engine that models traffic dynamics through diffusion, synchronisation, and spectral embeddings for comprehensive dynamic characterisation; (2) an adaptive consensus mechanism that dynamically fuses phase-specific predictions while enforcing consistency; and (3) a structured meta-learning strategy for rapid adaptation to new cities with minimal data. We establish extensive theoretical guarantees, including representation theorems with bounded approximation errors and generalisation bounds for few-shot adaptation. Through experiments on four real-world datasets, MCPST outperforms fourteen state-of-the-art methods in spatio-temporal graph learning methods, dynamic graph transfer learning methods, prompt-based spatio-temporal prediction methods and cross-domain few-shot settings, improving prediction accuracy while reducing required training data and providing interpretable insights. The implementation code is available at https://github.com/afofanah/MCPST.

cs.LG

Bridging the Semantic Chasm: Synergistic Conceptual Anchoring for Generalized Few-Shot and Zero-Shot OOD Perception

This manuscript presents a pioneering Synergistic Neural Agents Network (SynerNet) framework designed to mitigate the phenomenon of cross-modal alignment degeneration in Vision-Language Models (VLMs) when encountering Out-of-Distribution (OOD) concepts. Specifically, four specialized computational units - visual perception, linguistic context, nominal embedding, and global coordination - collaboratively rectify modality disparities via a structured message-propagation protocol. The principal contributions encompass a multi-agent latent space nomenclature acquisition framework, a semantic context-interchange algorithm for enhanced few-shot adaptation, and an adaptive dynamic equilibrium mechanism. Empirical evaluations conducted on the VISTA-Beyond benchmark demonstrate that SynerNet yields substantial performance augmentations in both few-shot and zero-shot scenarios, exhibiting precision improvements ranging from 1.2% to 5.4% across a diverse array of domains.

cs.CV

Prototype Learning to Create Refined Interpretable Digital Phenotypes from ECGs

Prototype-based neural networks offer interpretable predictions by comparing inputs to learned, representative signal patterns anchored in training data. While such models have shown promise in the classification of physiological data, it remains unclear whether their prototypes capture an underlying structure that aligns with broader clinical phenotypes. We use a prototype-based deep learning model trained for multi-label ECG classification using the PTB-XL dataset. Then without modification we performed inference on the MIMIC-IV clinical database. We assess whether individual prototypes, trained solely for classification, are associated with hospital discharge diagnoses in the form of phecodes in this external population. Individual prototypes demonstrate significantly stronger and more specific associations with clinical outcomes compared to the classifier's class predictions, NLP-extracted concepts, or broader prototype classes across all phecode categories. Prototype classes with mixed significance patterns exhibit significantly greater intra-class distances (p $<$ 0.0001), indicating the model learned to differentiate clinically meaningful variations within diagnostic categories. The prototypes achieve strong predictive performance across diverse conditions, with AUCs ranging from 0.89 for atrial fibrillation to 0.91 for heart failure, while also showing substantial signal for non-cardiac conditions such as sepsis and renal disease. These findings suggest that prototype-based models can support interpretable digital phenotyping from physiologic time-series data, providing transferable intermediate phenotypes that capture clinically meaningful physiologic signatures beyond their original training objectives.

cs.LG

ProtoECGNet: Case-Based Interpretable Deep Learning for Multi-Label ECG Classification with Contrastive Learning

Deep learning-based electrocardiogram (ECG) classification has shown impressive performance but clinical adoption has been slowed by the lack of transparent and faithful explanations. Post hoc methods such as saliency maps may fail to reflect a model's true decision process. Prototype-based reasoning offers a more transparent alternative by grounding decisions in similarity to learned representations of real ECG segments, enabling faithful, case-based explanations. We introduce ProtoECGNet, a prototype-based deep learning model for interpretable, multi-label ECG classification. ProtoECGNet employs a structured, multi-branch architecture that reflects clinical interpretation workflows: it integrates a 1D CNN with global prototypes for rhythm classification, a 2D CNN with time-localized prototypes for morphology-based reasoning, and a 2D CNN with global prototypes for diffuse abnormalities. Each branch is trained with a prototype loss designed for multi-label learning, combining clustering, separation, diversity, and a novel contrastive loss that encourages appropriate separation between prototypes of unrelated classes while allowing clustering for frequently co-occurring diagnoses. We evaluate ProtoECGNet on all 71 diagnostic labels from the PTB-XL dataset, demonstrating competitive performance relative to state-of-the-art black-box models while providing structured, case-based explanations. To assess prototype quality, we conduct a structured clinician review of the final model's projected prototypes, finding that they are rated as representative and clear. ProtoECGNet shows that prototype learning can be effectively scaled to complex, multi-label time-series classification, offering a practical path toward transparent and trustworthy deep learning models for clinical decision support.

cs.LG

Theoretical Corrections and the Leveraging of Reinforcement Learning to Enhance Triangle Attack

Adversarial examples represent a serious issue for the application of machine learning models in many sensitive domains. For generating adversarial examples, decision based black-box attacks are one of the most practical techniques as they only require query access to the model. One of the most recently proposed state-of-the-art decision based black-box attacks is Triangle Attack (TA). In this paper, we offer a high-level description of TA and explain potential theoretical limitations. We then propose a new decision based black-box attack, Triangle Attack with Reinforcement Learning (TARL). Our new attack addresses the limits of TA by leveraging reinforcement learning. This creates an attack that can achieve similar, if not better, attack accuracy than TA with half as many queries on state-of-the-art classifiers and defenses across ImageNet and CIFAR-10.

cs.LG

Multi-objective Bayesian optimization for Likelihood-Free inference in sequential sampling models of decision making

Statistical models are often defined by a generative process for simulating synthetic data, but this can lead to intractable likelihoods. Likelihood free inference (LFI) methods enable Bayesian inference to be performed in this case. Extending a popular approach to simulation-efficient LFI for single-source data, we propose Multi-objective Bayesian Optimization for Likelihood Free Inference (MOBOLFI) to perform LFI using multi-source data. MOBOLFI models a multi-dimensional discrepancy between observed and simulated data, using a separate discrepancy for each data source. The use of a multivariate discrepancy allows for approximations to individual data source likelihoods in addition to the joint likelihood, enabling detection of conflicting information and deeper understanding of the importance of different data sources in estimating individual parameters. The adaptive choice of simulation parameters using multi-objective Bayesian optimization ensures simulation efficient approximation of likelihood components for all data sources. We illustrate our approach in sequential sampling models (SSMs), which are widely used in psychology and consumer-behavior modeling. SSMs are often fitted using multi-source data, such as choice and response time. The advantages of our approach are illustrated in comparison with a single discrepancy for an SSM fitted to data assessing preferences of ride-hailing drivers in Singapore to rent electric vehicles.

stat.ME

concrete: Targeted Estimation of Survival and Competing Risks in Continuous Time

This article introduces the R package concrete, which implements a recently developed targeted maximum likelihood estimator (TMLE) for the cause-specific absolute risks of time-to-event outcomes measured in continuous time. Cross-validated Super Learner machine learning ensembles are used to estimate propensity scores and conditional cause-specific hazards, which are then targeted to produce robust and efficient plug-in estimates of the effects of static or dynamic interventions on a binary treatment given at baseline quantified as risk differences or risk ratios. Influence curve-based asymptotic inference is provided for TMLE estimates and simultaneous confidence bands can be computed for target estimands spanning multiple multiple times or events. In this paper we review the one-step continuous-time TMLE methodology as it is situated in an overarching causal inference workflow, describe its implementation, and demonstrate the use of the package on the PBC dataset.

stat.CO

Evaluating GPT's Programming Capability through CodeWars' Katas

In the burgeoning field of artificial intelligence (AI), understanding the capabilities and limitations of programming-oriented models is crucial. This paper presents a novel evaluation of the programming proficiency of Generative Pretrained Transformer (GPT) models, specifically GPT-3.5 and GPT-4, against coding problems of varying difficulty levels drawn from Codewars. The experiments reveal a distinct boundary at the 3kyu level, beyond which these GPT models struggle to provide solutions. These findings led to the proposal of a measure for coding problem complexity that incorporates both problem difficulty and the time required for solution. The research emphasizes the need for validation and creative thinking capabilities in AI models to better emulate human problem-solving techniques. Future work aims to refine this proposed complexity measure, enhance AI models with these suggested capabilities, and develop an objective measure for programming problem difficulty. The results of this research offer invaluable insights for improving AI programming capabilities and advancing the frontier of AI problem-solving abilities.

cs.AI

Multimodal Representation Learning of Cardiovascular Magnetic Resonance Imaging

Self-supervised learning is crucial for clinical imaging applications, given the lack of explicit labels in healthcare. However, conventional approaches that rely on precise vision-language alignment are not always feasible in complex clinical imaging modalities, such as cardiac magnetic resonance (CMR). CMR provides a comprehensive visualization of cardiac anatomy, physiology, and microstructure, making it challenging to interpret. Additionally, CMR reports require synthesizing information from sequences of images and different views, resulting in potentially weak alignment between the study and diagnosis report pair. To overcome these challenges, we propose \textbf{CMRformer}, a multimodal learning framework to jointly learn sequences of CMR images and associated cardiologist's reports. Moreover, one of the major obstacles to improving CMR study is the lack of large, publicly available datasets. To bridge this gap, we collected a large \textbf{CMR dataset}, which consists of 13,787 studies from clinical cases. By utilizing our proposed CMRformer and our collected dataset, we achieved remarkable performance in real-world clinical tasks, such as CMR image retrieval and diagnosis report retrieval. Furthermore, the learned representations are evaluated to be practically helpful for downstream applications, such as disease classification. Our work could potentially expedite progress in the CMR study and lead to more accurate and effective diagnosis and treatment.

cs.CV