arXiv subjects

David Weston

Publications and source records attributed to David Weston.

7 recordsLinked to original sources

arXiv2026

Exploring the Genesis Platform Capabilities to Accelerate Scientific Discovery in OPAL

Autonomous, cross-facility science requires capabilities that no individual project should have to build for itself: managed execution for long-lived services, versioned distribution of models to remote compute systems, governed access to large language models, a shared substrate for experimental data, and end-to-end provenance. The U.S. Department of Energy Genesis Mission platform, delivered through the American Science Cloud, provides these as reusable services. This paper reports how the Genesis platform enables cross-facility experiments and accelerates scientific discovery. We explore the plant phenotyping workflow of the Orchestrated Platform for Autonomous Laboratories as the exemplar: it couples Oak Ridge National Laboratory's Advanced Plant Phenotyping Laboratory with the Frontier supercomputer. In a 40-day nickel-treatment campaign, the resulting workflow replaced roughly twelve hours of manual analysis with interactive queries returning in seconds to minutes.

cs.DC↗

arXiv2026

An Agentic AI Framework to Accelerate Scientific Discovery in Plant Phenotyping

High-throughput plant phenotyping now generates image derived datasets far faster than scientists can analyze them. At Oak Ridge National Laboratory's Advanced Plant Phenotyping Laboratory (APPL), automated stations image hundreds of plants daily across multiple remote sensing modalities; yet, trait extraction and interpretation remain manual, expert-bound, and strictly post-hoc, making analysis, not acquisition, the binding constraint on discovery. We present an end-to-end agentic AI framework that turns the facility from a data factory into an interactive autonomous, discovery platform, where scientists partner with AI agents to accelerate time to insight. A conversational Co-Scientist Agent translates a scientist's natural-language question into a structured analysis plan, and a headless Compute Agent dispatches Vision Transformer segmentation and trait extraction on the Frontier exascale supercomputer. The two agents run in separate security and resource domains and communicate over a secure, token-authenticated streaming channel, a design that accounts for the federation, data-movement, and provenance realities cloud-native agentic frameworks ignore, ensuring end-to-end provenance is captured for every interaction. The framework turns a days- to weeks-long analysis process into an interactive loop where agents reason over results, recommend next analyses, and respond to follow-up questions in seconds.

cs.AI↗

arXiv2023

Incorporating Dictionaries into a Neural Network Architecture to Extract COVID-19 Medical Concepts From Social Media

We investigate the potential benefit of incorporating dictionary information into a neural network architecture for natural language processing. In particular, we make use of this architecture to extract several concepts related to COVID-19 from an on-line medical forum. We use a sample from the forum to manually curate one dictionary for each concept. In addition, we use MetaMap, which is a tool for extracting biomedical concepts, to identify a small number of semantic concepts. For a supervised concept extraction task on the forum data, our best model achieved a macro $F_1$ score of 90\%. A major difficulty in medical concept extraction is obtaining labelled data from which to build supervised models. We investigate the utility of our models to transfer to data derived from a different source in two ways. First for producing labels via weak learning and second to perform concept extraction. The dataset we use in this case comprises COVID-19 related tweets and we achieve an $F_1$ score 81\% for symptom concept extraction trained on weakly labelled data. The utility of our dictionaries is compared with a COVID-19 symptom dictionary that was constructed directly from Twitter. Further experiments that incorporate BERT and a COVID-19 version of BERTweet demonstrate that the dictionaries provide a commensurate result. Our results show that incorporating small domain dictionaries to deep learning models can improve concept extraction tasks. Moreover, models built using dictionaries generalize well and are transferable to different datasets on a similar task.

cs.CL↗

arXiv2023

Probabilistic Measures for Biological Adaptation and Resilience

This paper introduces a novel approach to quantifying ecological resilience in biological systems, particularly focusing on noisy systems responding to episodic disturbances with sudden adaptations. Incorporating concepts from non-equilibrium statistical mechanics, we propose a measure termed `ecological resilience through adaptation,' specifically tailored to noisy, forced systems that undergo physiological adaptation in the face of stressful environmental changes. Randomness plays a key role, accounting for model uncertainty and the inherent variability in the dynamical response among components of biological systems. Our measure of resilience is rooted in the probabilistic description of states within these systems, and is defined in terms of the dynamics of the ensemble average of a model-specific observable quantifying success or well-being. Our approach utilizes stochastic linear response theory to compute how the expected success of a system, originally in statistical equilibrium, dynamically changes in response to a environmental perturbation and a subsequent adaptation. The resulting mathematical derivations allow for the estimation of resilience in terms of ensemble averages of simulated or experimental data. Finally, through a simple but clear conceptual example, we illustrate how our resilience measure can be interpreted and compared to other existing frameworks in the literature. The methodology is general but inspired by applications in plant systems, with the potential for broader application to complex biological processes.

q-bio.QM↗

arXiv2022

Monitoring Covid-19 on social media using a novel triage and diagnosis approach

Objective: This study aims to develop an end-to-end natural language processing pipeline for triage and diagnosis of COVID-19 from patient-authored social media posts, in order to provide researchers and public health practitioners with additional information on the symptoms, severity and prevalence of the disease rather than to provide an actionable decision at the individual level. Materials and Methods: The text processing pipeline first extracts COVID-19 symptoms and related concepts such as severity, duration, negations, and body parts from patients' posts using conditional random fields. An unsupervised rule-based algorithm is then applied to establish relations between concepts in the next step of the pipeline. The extracted concepts and relations are subsequently used to construct two different vector representations of each post. These vectors are applied separately to build support vector machine learning models to triage patients into three categories and diagnose them for COVID-19. Results: We report that macro- and micro-averaged F1 scores in the range of 71-96% and 61-87%, respectively, for the triage and diagnosis of COVID-19, when the models are trained on human labelled data. Our experimental results indicate that similar performance can be achieved when the models are trained using predicted labels from concept extraction and rule-based classifiers, thus yielding end-to-end machine learning. Also, we highlight important features uncovered by our diagnostic machine learning models and compare them with the most frequent symptoms revealed in another COVID-19 dataset. In particular, we found that the most important features are not always the most frequent ones.

cs.CL↗

arXiv2020

Supervised Phrase-boundary Embeddings

We propose a new word embedding model, called SPhrase, that incorporates supervised phrase information. Our method modifies traditional word embeddings by ensuring that all target words in a phrase have exactly the same context. We demonstrate that including this information within a context window produces superior embeddings for both intrinsic evaluation tasks and downstream extrinsic tasks.

cs.CL↗

arXiv2018

Modelling Metropolitan-area Ambulance Mobility under Blue Light Conditions

Actions taken immediately following a life-threatening personal health incident are critical for the survival of the sufferer. The timely arrival of specialist ambulance crew in particular often makes the difference between life and death. As a consequence, it is critical that emergency ambulance services achieve short response times. This objective sets a considerable challenge to ambulance services worldwide, especially in metropolitan areas where the density of incident occurrence and traffic congestion are high. Using London as a case study, in this paper we consider the advantages and limitations of data-driven methods for ambulance routing and navigation. Our long-term aim is to enable considerable improvements to their operational efficiency through the automated generation of more effective response strategies and tactics. A key ingredient of our approach is to use a large historical dataset of incidents and ambulance location traces to model route selection and arrival times. Working on the London road network graph modified to reflect the differences between emergency and civilian vehicle traffic, we develop a methodology for the precise estimation of expected ambulance speed at the individual road segment level. We demonstrate how a model that exploits this information achieves best predictive performance by implicitly capturing route-specific persistent patterns in changing traffic conditions. We then present a predictive method that achieves a high route similarity score while minimising journey duration error. This is achieved through the combination of a technique that correctly predicts routes selected by the current navigation system of the London Ambulance Service and our best performing speed estimation model. This hybrid approach outperforms alternative mobility models.

cs.CY↗