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Davide Baroli

Publications and source records attributed to Davide Baroli.

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Probabilistic energy forecasting through quantile regression in reproducing kernel Hilbert spaces

Accurate energy demand forecasting is crucial for sustainable and resilient energy development. To meet the Net Zero Representative Concentration Pathways (RCP) $4.5$ scenario in the DACH countries, increased renewable energy production, energy storage, and reduced commercial building consumption are needed. This scenario's success depends on hydroelectric capacity and climatic factors. Informed decisions require quantifying uncertainty in forecasts. This study explores a non-parametric method based on \emph{reproducing kernel Hilbert spaces (RKHS)}, known as kernel quantile regression, for energy prediction. Our experiments demonstrate its reliability and sharpness, and we benchmark it against state-of-the-art methods in load and price forecasting for the DACH region. We offer our implementation in conjunction with additional scripts to ensure the reproducibility of our research.

cs.LG

Samplet basis pursuit: Multiresolution scattered data approximation with sparsity constraints

We consider scattered data approximation in samplet coordinates with $\ell_1$-regularization. The application of an $\ell_1$-regularization term enforces sparsity of the coefficients with respect to the samplet basis. Samplets are wavelet-type signed measures, which are tailored to scattered data. Therefore, samplets enable the use of well-established multiresolution techniques on general scattered data sets. They provide similar properties as wavelets in terms of localization, multiresolution analysis, and data compression. By using the Riesz isometry, we embed samplets into reproducing kernel Hilbert spaces and discuss the properties of the resulting functions. We argue that the class of signals that are sparse with respect to the embedded samplet basis is considerably larger than the class of signals that are sparse with respect to the basis of kernel translates. Vice versa, every signal that is a linear combination of only a few kernel translates is sparse in samplet coordinates. We propose the rapid solution of the problem under consideration by combining soft-shrinkage with the semi-smooth Newton method. Leveraging on the sparse representation of kernel matrices in samplet coordinates, this approach converges faster than the fast iterative shrinkage thresholding algorithm and is feasible for large-scale data. Numerical benchmarks are presented and demonstrate the superiority of the multiresolution approach over the single-scale approach. As large-scale applications, the surface reconstruction from scattered data and the reconstruction of scattered temperature data using a dictionary of multiple kernels are considered.

stat.ML

Multi-compartment poroelastic models of perfused biological soft tissues: implementation in FEniCSx

Soft biological tissues demonstrate strong time-dependent and strain-rate mechanical behavior, arising from their intrinsic visco-elasticity and fluid-solid interactions (especially at sufficiently large time scales). The time-dependent mechanical properties of soft tissues influence their physiological functions and are linked to several pathological processes. Poro-elastic modeling represents a promising approach because it allows the integration of multiscale/multiphysics data to probe biologically relevant phenomena at a smaller scale and embeds the relevant mechanisms at the larger scale. The implementation of multi-phasic flow poro-elastic models however is a complex undertaking, requiring extensive knowledge. The open-source software FEniCSx Project provides a novel tool for the automated solution of partial differential equations by the finite element method. This paper aims to provide the required tools to model the mixed formulation of poro-elasticity, from the theory to the implementation, within FEniCSx. Several benchmark cases are studied. A column under confined compression conditions is compared to the Terzaghi analytical solution, using the L2-norm. An implementation of poro-hyper-elasticity is proposed. A bi-compartment column is compared to previously published results (Cast3m implementation). For all cases, accurate results are obtained in terms of a normalized Root Mean Square Error (RMSE). Furthermore, the FEniCSx computation is found three times faster than the legacy FEniCS one. The benefits of parallel computation are also highlighted.

q-bio.TO

Oncology and mechanics: landmark studies and promising clinical applications

Clinical management of cancer has continuously evolved for several decades. Biochemical, molecular and genomics approaches have brought and still bring numerous insights into cancerous diseases. It is now accepted that some phenomena, allowed by favorable biological conditions, emerge via mechanical signaling at the cellular scale and via mechanical forces at the macroscale. Mechanical phenomena in cancer have been studied in-depth over the last decades, and their clinical applications are starting to be understood. If numerous models and experimental setups have been proposed, only a few have led to clinical applications. The objective of this contribution is to propose to review a large scope of mechanical findings which have consequences on the clinical management of cancer. This review is mainly addressed to doctoral candidates in mechanics and applied mathematics who are faced with the challenge of the mechanics-based modeling of cancer with the aim of clinical applications. We show that the collaboration of the biological and mechanical approaches has led to promising advances in terms of modeling, experimental design and therapeutic targets. Additionally, a specific focus is brought on imaging-informed mechanics-based models, which we believe can further the development of new therapeutic targets and the advent of personalized medicine. We study in detail several successful workflows on patient-specific targeted therapies based on mechanistic modeling.

q-bio.TO

Simulating the spread of COVID-19 via spatially-resolved susceptible-exposed-infected-recovered-deceased (SEIRD) model with heterogeneous diffusion

We present an early version of a Susceptible-Exposed-Infected-Recovered-Deceased (SEIRD) mathematical model based on partial differential equations coupled with a heterogeneous diffusion model. The model describes the spatio-temporal spread of the COVID-19 pandemic, and aims to capture dynamics also based on human habits and geographical features. To test the model, we compare the outputs generated by a finite-element solver with measured data over the Italian region of Lombardy, which has been heavily impacted by this crisis between February and April 2020. Our results show a strong qualitative agreement between the simulated forecast of the spatio-temporal COVID-19 spread in Lombardy and epidemiological data collected at the municipality level. Additional simulations exploring alternative scenarios for the relaxation of lockdown restrictions suggest that reopening strategies should account for local population densities and the specific dynamics of the contagion. Thus, we argue that data-driven simulations of our model could ultimately inform health authorities to design effective pandemic-arresting measures and anticipate the geographical allocation of crucial medical resources.

q-bio.PE