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Deborah Volpe

Publications and source records attributed to Deborah Volpe.

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Fidelity-Aware Scheduling of Quantum Circuits on Multi-QPU Systems

High Performance Computing-Quantum Computing (HPCQC) platforms expose multiple Quantum Processing Units (QPUs) that may differ in size, topology, native gates, and noise characteristics. For current noisy devices, errors compound along the compiled circuits quickly, and minimizing them, that is, maximizing the circuits' execution fidelity, is essential for reliable results. Fidelity depends on the compilation to a specific target device: the same high-level circuit may produce different executables and, therefore, different expected fidelities across QPUs. We present a low-overhead fidelity-aware scheduling framework for multi-QPU systems based on a Graph Neural Network (GNN) that estimates, before compilation, the expected fidelity of each circuit on each available QPU. Then, a tunable scheduler uses these estimates to control the trade-off between execution fidelity and parallelism. Results show that this framework allows for approximating an exhaustive fidelity-based assignment, saving computational resources compared to a brute-force approach that compiles each circuit on every device.

quant-ph

FIREQ: FPGA Instrumentation for Readout and Qubit control

We present FIREQ (FPGA Instrumentation for Readout and Qubit control), an open-source RFSoC-based framework for the control and readout of superconducting qubits. FIREQ combines a modular AXI-compliant firmware architecture with a PYNQ-based software stack designed to support extensible hardware integration, deterministic experiment timing, and low-overhead execution of repeated calibration and characterization workflows. The firmware implements direct RF synthesis and acquisition, trigger-based sequencing, programmable pulse generation, frequency-multiplexed readout, and memory-efficient acquisition and waveform buffering. The software adopts a client-server architecture with streamed data transfer and dependency-aware configuration updates to reduce host-device and reconfiguration overhead during parameter sweeps. On an AMD Zynq UltraScale+ RFSoC ZCU216, FIREQ generates RF pulses up to 9.3 GHz with a pulse-duration resolution of 107 ps and an event-timing resolution of 1.7 ns. FPGA resource utilization is compared with representative open-source RFSoC control frameworks, showing a low BRAM footprint while retaining full-rate I/Q generation and acquisition. The RF output is characterized in terms of phase noise, noise spectral density, and inter-channel timing skew. End-to-end operation is validated on a superconducting qubit through resonator spectroscopy, Rabi, Ramsey, and relaxation measurements, yielding T1 = 6.94 us and T2* = 13.50 us. FIREQ can therefore be used both as a qubit-control platform and as an experimental environment for evaluating alternative control and readout IP architectures.

quant-ph

A scalable and resource-efficient pipelined p-computer for probabilistic Ising machines

Probabilistic Ising machines (PIMs) based on probabilistic bits offer a hardware-friendly route to solve combinatorial optimization problems, but most digital implementations achieve high throughput by exploiting sparse interactions. This limits their applicability to dense problems, for which memory bandwidth and data movement become the dominant bottlenecks. Here, we show a resource-efficient pipelined Field-Programmable Gate Array architecture enabling high-throughput execution of fully-connected PIMs while maintaining scalability and modularity. This architecture design combines a deeply pipelined (>20 stages) probabilistic bit update path, which overlaps spin evaluation and local-field updates, with a bandwidth-aware on-chip memory organization for the coupling and bias matrices. The architecture supports 512 p-bits with 16-bit fixed-point coefficients and 1024 and 2048 p-bits with 10-bit and 2-bit coefficients, respectively, and operates at up to 300 MHz. At fixed degree of parallelization, it delivers an order-of-magnitude higher update rate than an optimized non-pipelined baseline, while improving the time-area trade-off for dense workloads. Validation on portfolio optimization and low-density parity-check decoding shows close agreement with software references and substantial reductions in time-to-solution relative to the non-pipelined design, establishing pipelining as an effective route to scalable digital probabilistic computing for dense optimization problems.

eess.SY

Physics-Inspired Probabilistic Computing for Extremely Large-Scale MIMO Detection in Future 6G Wireless Systems

Extremely large-scale multiple-input multiple-output (XL-MIMO) architectures are a key enabler of forthcoming 6G wireless communication networks by allowing high data rates through massive spatial multiplexing. Here, we approach these problems with physics-inspired unconventional computing based on Ising machines (IMs). For binary modulation, probabilistic IMs (PIMs) and oscillator-based IMs achieve optimal ML detection with systems up to 2048x2048 antennas with only 100 iterations, matching optimal sphere decoder performance for computationally treatable sizes and outperforming the minimum mean-square error (MMSE) industrial standard. For M-QAM up to 256, a generalized PIM-inspired framework, based on d-dimensional probabilistic variables (p-dits) that directly encode QAM symbols, shows low bit-error-rate across sizes up to 256x256 antennas, outperforming or matching MMSE with reduced algorithmic complexity. Unlike the binary mapping, the p-dit interaction matrix is independent of the QAM order, enabling adaptive MIMO modulation. These results show a promising scalable paradigm for XL MIMO detection in future 6G networks.

cs.IT

High-Parallel FPGA-Based Discrete Simulated Bifurcation for Large-Scale Optimization

Combinatorial Optimization (CO) problems exhibit exponential complexity, making their resolution challenging. Simulated Adiabatic Bifurcation (aSB) is a quantum-inspired algorithm to obtain approximate solutions to largescale CO problems written in the Ising form. It explores the solution space by emulating the adiabatic evolution of a network of Kerr-nonlinear parametric oscillators (KPOs), where each oscillator represents a variable in the problem. The optimal solution corresponds to the ground state of this system. A key advantage of this approach is the possibility of updating multiple variables simultaneously, making it particularly suited for hardware implementation. To enhance solution quality and convergence speed, variations of the algorithm have been proposed in the literature, including ballistic (bSB), discrete (dSB), and thermal (HbSB) versions. In this work, we have comprehensively analyzed dSB, bSB, and HbSB using dedicated software models, evaluating the feasibility of using a fixed-point representation for hardware implementation. We then present an opensource hardware architecture implementing the dSB algorithm for Field-Programmable Gate Arrays (FPGAs). The design allows users to adjust the degree of algorithmic parallelization based on their specific requirements. A proof-of-concept implementation that solves 256-variable problems was achieved on an AMD Kria KV260 SoM, a low-tier FPGA, validated using well-known max-cut and knapsack problems.

eess.SY

A Quantum-Compliant Formulation for Network Epidemic Control

We deal with controlling the spread of an epidemic disease on a network by isolating one or multiple locations by banning people from leaving them. To this aim, we build on the susceptible-infected-susceptible and the susceptible-infected-removed discrete-time network models, encapsulating a control action that captures mobility bans via removing links from the network. Then, we formulate the problem of optimally devising a control policy based on mobility bans that trades-off the burden on the healthcare system and the social and economic costs associated with interventions. The binary nature of mobility bans hampers the possibility to solve the control problem with standard optimization methods, yielding a NP-hard problem. Here, this is tackled by deriving a Quadratic Unconstrained Binary Optimization (QUBO) formulation of the control problem, and leveraging the growing potentialities of quantum computing to efficiently solve it.

eess.SY

Graph Neural Network-Based Predictor for Optimal Quantum Hardware Selection

The growing variety of quantum hardware technologies, each with unique peculiarities such as connectivity and native gate sets, creates challenges when selecting the best platform for executing a specific quantum circuit. This selection process usually involves a brute-force approach: compiling the circuit on various devices and evaluating performance based on factors such as circuit depth and gate fidelity. However, this method is computationally expensive and does not scale well as the number of available quantum processors increases. In this work, we propose a Graph Neural Network (GNN)-based predictor that automates hardware selection by analyzing the Directed Acyclic Graph (DAG) representation of a quantum circuit. Our study evaluates 498 quantum circuits (up to 27 qubits) from the MQT Bench dataset, compiled using Qiskit on four devices: three superconducting quantum processors (IBM-Kyiv, IBM-Brisbane, IBM-Sherbrooke) and one trapped-ion processor (IONQ-Forte). Performance is estimated using a metric that integrates circuit depth and gate fidelity, resulting in a dataset where 93 circuits are optimally compiled on the trapped-ion device, while the remaining circuits prefer superconducting platforms. By exploiting graph-based machine learning, our approach avoids extracting the circuit features for the model evaluation but directly embeds it as a graph, significantly accelerating the optimal target decision-making process and maintaining all the information. Experimental results prove 94.4% accuracy and an 85.5% F1 score for the minority class, effectively predicting the best compilation target. The developed code is publicly available on GitHub (https://github.com/antotu/GNN-Model-Quantum-Predictor).

quant-ph

A Quantum Approach for Optimal Transient Control in Network-Based Epidemic Models

Effective epidemic control is crucial for mitigating the spread of infectious diseases, particularly when pharmaceutical interventions such as vaccines or treatments are limited. Non-pharmaceutical strategies, including mobility restrictions, are key in reducing transmission rates but require careful optimization to balance public health benefits and socioeconomic costs. Quantum computing is emerging as a powerful tool for solving complex optimization problems that are intractable for classical methods and can thus be leveraged to handle mobility restrictions. This article presents a new approach to optimizing epidemic control strategies using quantum computing techniques. We focus on non-pharmaceutical interventions, particularly mobility restriction, modeled as a discrete-time network epidemic process based on the susceptible-infected-susceptible and susceptible-infected-removed frameworks. The control problem is formulated as a combinatorial optimization task, inherently NP-hard due to the binary nature of intervention decisions. To tackle this computational complexity, we derive a Quadratic Unconstrained Binary Optimization representation of the control problem, enabling its efficient solution via quantum computing resources. Our methodology is validated through numerical simulations on realistic case studies, showcasing the potential of quantum algorithms for enhancing epidemic control strategies. These findings pave the way for leveraging quantum optimization in broader applications of networked dynamical systems, demonstrating its viability for complex decision-making processes in public health management.

physics.soc-ph

AEQUAM: Accelerating Quantum Algorithm Validation through FPGA-Based Emulation

This work presents AEQUAM (Area Efficient QUAntum eMulation), a toolchain that enables faster and more accessible quantum circuit verification. It consists of a compiler that translates OpenQASM 2.0 into RISC-like instructions, Cython software models for selecting number representations and simulating circuits, and a VHDL generator that produces RTL descriptions for FPGA-based hardware emulators. The architecture leverages a SIMD approach to parallelize computation and reduces complexity by exploiting the sparsity of quantum gate matrices. The VHDL generator allows customization of the number of emulated qubits and parallelization levels to meet user requirements. Synthesized on an Altera Cyclone 10LP FPGA with a 20-bit fixed-point representation and nearest-type approximation, the architecture demonstrates better scalability than other state-of-the-art emulators. Specifically, the emulator has been validated by exploiting the well consolidated benchmark of mqt bench framework.

quant-ph

Extended-variable probabilistic computing with p-dits

Ising machines can solve combinatorial optimization problems by representing them as energy minimization problems. A common implementation is the probabilistic Ising machine (PIM), which uses probabilistic (p-) bits to represent coupled binary spins. However, many real-world problems have complex data representations that do not map naturally into a binary encoding, leading to a significant increase in hardware resources and time-to-solution. Here, we describe a generalized spin model that supports an arbitrary number of spin dimensions, each with an arbitrary real component. We define the probabilistic d-dimensional bit (p-dit) as the base unit of a p-computing implementation of this model. We further describe two restricted forms of p-dits for specific classes of common problems and implement them experimentally on an application-specific integrated circuit (ASIC): (A) isotropic p-dits, which simplify the implementation of categorical variables resulting in ~34x performance improvement compared to a p-bit implementation on an example 3-partition problem. (B) Probabilistic integers (p-ints), which simplify the representation of numeric values and provide ~5x improvement compared to a p-bit implementation of an example integer linear programming (ILP) problem. Additionally, we report a field-programmable gate array (FPGA) p-int-based integer quadratic programming (IQP) solver which shows ~64x faster time-to-solution compared to the best of a series of state-of-the-art software solvers. The generalized formulation of probabilistic variables presented here provides a path to solving large-scale optimization problems on various hardware platforms including digital CMOS.

physics.app-ph

Quantum Machine Learning in Healthcare: Evaluating QNN and QSVM Models

Effective and accurate diagnosis of diseases such as cancer, diabetes, and heart failure is crucial for timely medical intervention and improving patient survival rates. Machine learning has revolutionized diagnostic methods in recent years by developing classification models that detect diseases based on selected features. However, these classification tasks are often highly imbalanced, limiting the performance of classical models. Quantum models offer a promising alternative, exploiting their ability to express complex patterns by operating in a higher-dimensional computational space through superposition and entanglement. These unique properties make quantum models potentially more effective in addressing the challenges of imbalanced datasets. This work evaluates the potential of quantum classifiers in healthcare, focusing on Quantum Neural Networks (QNNs) and Quantum Support Vector Machines (QSVMs), comparing them with popular classical models. The study is based on three well-known healthcare datasets -- Prostate Cancer, Heart Failure, and Diabetes. The results indicate that QSVMs outperform QNNs across all datasets due to their susceptibility to overfitting. Furthermore, quantum models prove the ability to overcome classical models in scenarios with high dataset imbalance. Although preliminary, these findings highlight the potential of quantum models in healthcare classification tasks and lead the way for further research in this domain.

cs.LG

Multi-VQC: A Novel QML Approach for Enhancing Healthcare Classification

Accurate and reliable diagnosis of diseases is crucial in enabling timely medical treatment and enhancing patient survival rates. In recent years, Machine Learning has revolutionized diagnostic practices by creating classification models capable of identifying diseases. However, these classification problems often suffer from significant class imbalances, which can inhibit the effectiveness of traditional models. Therefore, the interest in Quantum models has arisen, driven by the captivating promise of overcoming the limitations of the classical counterpart thanks to their ability to express complex patterns by mapping data in a higher-dimensional computational space.

cs.LG

AMARETTO: Enabling Efficient Quantum Algorithm Emulation on Low-Tier FPGAs

Researchers and industries are increasingly drawn to quantum computing for its computational potential. However, validating new quantum algorithms is challenging due to the limitations of current quantum devices. Software simulators are time and memory-consuming, making hardware emulators an attractive alternative. This article introduces AMARETTO (quAntuM ARchitecture EmulaTion TechnOlogy), designed for quantum computing emulation on low-tier Field-Programmable gate arrays (FPGAs), supporting Clifford+T and rotational gate sets. It simplifies and accelerates the verification of quantum algorithms using a Reduced-Instruction-Set-Computer (RISC)-like structure and efficient handling of sparse quantum gates. A dedicated compiler translates OpenQASM 2.0 into RISC-like instructions. AMARETTO is validated against the Qiskit simulators. Our results show successful emulation of sixteen qubits on a AMD Kria KV260 SoM. This approach rivals other works in emulated qubit capacity on a smaller, more affordable FPGA

quant-ph

Quantum optimization for Nonlinear Model Predictive Control

Nonlinear Model Predictive Control (NMPC) is a general and flexible control approach, used in many industrial contexts, and is based on the online solution of a nonlinear optimization problem. This operation requires in general a high computational cost, which may compromise the NMPC implementation in ``fast'' applications, especially if a large number variables is involved. To overcome this issue, we propose a quantum computing approach for the solution of the NMPC optimization problem. Assuming the availability of an efficient quantum computer, the approach has the potential to considerably decrease the computational time and/or enhance the solution quality compared to classical algorithms.

eess.SY

A Predictive Approach for Selecting the Best Quantum Solver for an Optimization Problem

Leveraging quantum computers for optimization problems holds promise across various application domains. Nevertheless, utilizing respective quantum computing solvers requires describing the optimization problem according to the Quadratic Unconstrained Binary Optimization (QUBO) formalism and selecting a proper solver for the application of interest with a reasonable setting. Both demand significant proficiency in quantum computing, QUBO formulation, and quantum solvers, a background that usually cannot be assumed by end users who are domain experts rather than quantum computing specialists. While tools aid in QUBO formulations, support for selecting the best-solving approach remains absent. This becomes even more challenging because selecting the best solver for a problem heavily depends on the problem itself. In this work, we are accepting this challenge and propose a predictive selection approach, which aids end users in this task. To this end, the solver selection task is first formulated as a classification task that is suitable to be solved by supervised machine learning. Based on that, we then propose strategies for adjusting solver parameters based on problem size and characteristics. Experimental evaluations, considering more than 500 different QUBO problems, confirm the benefits of the proposed solution. In fact, we show that in more than 70% of the cases, the best solver is selected, and in about 90% of the problems, a solver in the top two, i.e., the best or its closest suboptimum, is selected. This exploration proves the potential of machine learning in quantum solver selection and lays the foundations for its automation, broadening access to quantum optimization for a wider range of users.

quant-ph

Towards an Automatic Framework for Solving Optimization Problems with Quantum Computers

Optimizing objective functions stands to benefit significantly from leveraging quantum computers, promising enhanced solution quality across various application domains in the future. However, harnessing the potential of quantum solvers necessitates formulating problems according to the Quadratic Unconstrained Binary Optimization (QUBO) model, demanding significant expertise in quantum computation and QUBO formulations. This expertise barrier limits access to quantum solutions. Fortunately, automating the conversion of conventional optimization problems into QUBO formulations presents a solution for promoting accessibility to quantum solvers. This article addresses the unmet need for a comprehensive automatic framework to assist users in utilizing quantum solvers for optimization tasks while preserving interfaces that closely resemble conventional optimization practices. The framework prompts users to specify variables, optimization criteria, as well as validity constraints and, afterwards, allows them to choose the desired solver. Subsequently, it automatically transforms the problem description into a format compatible with the chosen solver and provides the resulting solution. Additionally, the framework offers instruments for analyzing solution validity and quality. Comparative analysis against existing libraries and tools in the literature highlights the comprehensive nature of the proposed framework. Two use cases (the knapsack problem and linear regression) are considered to show the completeness and efficiency of the framework in real-world applications. Finally, the proposed framework represents a significant advancement towards automating quantum computing solutions and widening access to quantum optimization for a broader range of users.

quant-ph