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Demao Liu

Publications and source records attributed to Demao Liu.

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Joint Discovery of Graph Structure and Dynamics in Stochastic Interacting Particle Systems

We study the joint identification of network structure and governing dynamics in stochastic interacting particle systems, which consist of an unknown directed weighted interaction graph with unknown local and non-local interaction components. We formulate the problem as a coupled inverse problem for the graph and the associated basis coefficients, and develop two alternating least-squares-type estimators: a three-block scheme (TALS) and an integrated diagonal-augmented scheme (IALS). The IALS formulation combines the updates of the local and interaction coefficients into a single least-squares subproblem, and is particularly well suited to settings in which the nodewise local dynamics share a common functional template up to node-dependent scaling. We further establish an identifiability result under a rank-2 joint coercivity condition together with an appropriate normalization convention. Synthetic experiments show that the proposed estimators accurately recover both the interaction graph and the dynamical components, and remain robust under stochastic forcing, observation noise, and basis mismatch. We also provide an illustrative real-data application on ictal SEEG recordings, where the learned models produce stable and interpretable dynamical summaries across multiple basis configurations. This work advances a theoretically guaranteed scalable framework for learning stochastic interacting particle systems, with broad potential for data-driven identification in computational biology, neuroscience, and beyond.

cs.SI

Artificial intelligence as a surrogate brain: Bridging neural dynamical models and data

Recent breakthroughs in artificial intelligence (AI) are reshaping the way we construct computational counterparts of the brain, giving rise to a new class of ``surrogate brains''. In contrast to conventional hypothesis-driven biophysical models, the AI-based surrogate brain encompasses a broad spectrum of data-driven approaches to solve the inverse problem, with the primary objective of accurately predicting future whole-brain dynamics with historical data. Here, we introduce a unified framework of constructing an AI-based surrogate brain that integrates forward modeling, inverse problem solving, and model evaluation. Leveraging the expressive power of AI models and large-scale brain data, surrogate brains open a new window for decoding neural systems and forecasting complex dynamics with high dimensionality, nonlinearity, and adaptability. We highlight that the learned surrogate brain serves as a simulation platform for dynamical systems analysis, virtual perturbation, and model-guided neurostimulation. We envision that the AI-based surrogate brain will provide a functional bridge between theoretical neuroscience and translational neuroengineering.

q-bio.NC