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Demetri Psaltis

Publications and source records attributed to Demetri Psaltis.

At least 37 records · Page 2Linked to original sources

Single-cell phase-contrast tomograms data encoded by 3D Zernike descriptors

Phase-contrast tomographic flow cytometry combines quantitative 3D analysis of unstained single cells and high-throughput. A crucial issue of this method is the storage and management of the huge amount of 3D tomographic data. Here we show an effective quasi lossless compression of tomograms data through 3D Zernike descriptors, unlocking data management tasks and computational pipelines that were unattainable until now.

physics.optics↗

Optical Diffraction Tomography based on 3D Physics-Inspired Neural Network (PINN)

Optical diffraction tomography (ODT) is an emerging 3D imaging technique that is used for the 3D reconstruction of the refractive index (RI) for semi-transparent samples. Various inverse models have been proposed to reconstruct the 3D RI based on the holographic detection of different samples such as the Born and the Rytov approximations. However, such approximations usually suffer from the so-called missing-cone problem that results in an elongation of the final reconstruction along the optical axis. Different iterative schemes have been proposed to solve the missing cone problem relying on physical forward models and an error function that aims at filling in the k-space and thus eliminating the missing-cone problem and reaching better reconstruction accuracy. In this paper, we propose a different approach where a 3D neural network (NN) is employed. The NN is trained with a cost function derived from a physical model based on the physics of optical wave propagation. The 3D NN starts with an initial guess for the 3D RI reconstruction (i.e. Born, or Rytov) and aims at reconstructing better 3D reconstruction based on an error function. With this technique, the NN can be trained without any examples of the relation between the ill-posed reconstruction (Born or Rytov) and the ground truth (true shape).

physics.optics↗

Roadmap on Wavefront Shaping and deep imaging in complex media

The last decade has seen the development of a wide set of tools, such as wavefront shaping, computational or fundamental methods, that allow to understand and control light propagation in a complex medium, such as biological tissues or multimode fibers. A vibrant and diverse community is now working on this field, that has revolutionized the prospect of diffraction-limited imaging at depth in tissues. This roadmap highlights several key aspects of this fast developing field, and some of the challenges and opportunities ahead.

physics.optics↗

Variational framework for partially-measured physical system control: examples of vision neuroscience and optical random media

To characterize a physical system to behave as desired, either its underlying governing rules must be known a priori or the system itself be accurately measured. The complexity of full measurements of the system scales with its size. When exposed to real-world conditions, such as perturbations or time-varying settings, the system calibrated for a fixed working condition might require non-trivial re-calibration, a process that could be prohibitively expensive, inefficient and impractical for real-world use cases. In this work, we propose a learning procedure to obtain a desired target output from a physical system. We use Variational Auto-Encoders (VAE) to provide a generative model of the system function and use this model to obtain the required input of the system that produces the target output. We showcase the applicability of our method for two datasets in optical physics and neuroscience.

cs.LG↗

Direct (3+1)D laser writing of graded-index optical elements

We propose single-step additive fabrication of graded-index optical elements by introducing the light exposure as the additional dimension to three-dimensional (3D) laser writing, hence (3+1)D writing. We use a commercial printer and photoresist to realize the proposed single step fabrication method that can be swiftly adopted for research and engineering. After presenting the characterization of the graded-index profiles via basic structures, we demonstrate two different optical devices: volume holograms that are superimposed using angular and peristrophic multiplexing, and optical waveguides with well-defined refractive index profiles. In the latter, we precisely control the propagating modes via tuning the (3+1)D-printed waveguide parameters and report step-index and graded-index core-cladding transitions.

physics.optics↗

MaxwellNet: Physics-driven deep neural network training based on Maxwell's equations

Maxwell's equations govern light propagation and its interaction with matter. Therefore, the solution of Maxwell's equations using computational electromagnetic simulations plays a critical role in understanding light-matter interaction and designing optical elements. Such simulations are often time-consuming and recent activities have been described to replace or supplement them with trained deep neural networks (DNNs). Such DNNs typically require extensive, computationally demanding simulations using conventional electromagnetic solvers to compose the training dataset. In this paper, we present a novel scheme to train a DNN that solves Maxwell's equations speedily and accurately without relying on other computational electromagnetic solvers. Our approach is to train a DNN using the residual of Maxwell's equations as the physics-driven loss function for a network that finds the electric field given the spatial distribution of the material property. We demonstrate it by training a single network that simultaneously finds multiple solutions of various aspheric micro-lenses. Furthermore, we exploit the speed of this network in a novel inverse design scheme to design a micro-lens that maximizes a desired merit function. We believe that our approach opens up a novel way for light simulation and optical design of photonics devices.

physics.optics↗

Scalable Optical Learning Operator

Today's heavy machine learning tasks are fueled by large datasets. Computing is performed with power hungry processors whose performance is ultimately limited by the data transfer to and from memory. Optics is one of the powerful means of communicating and processing information and there is intense current interest in optical information processing for realizing high-speed computations. Here we present and experimentally demonstrate an optical computing framework based on spatiotemporal effects in multimode fibers for a range of learning tasks from classifying COVID-19 X-ray lung images and speech recognition to predicting age from face images. The presented framework overcomes the energy scaling problem of existing systems without compromising speed. We leveraged simultaneous, linear, and nonlinear interaction of spatial modes as a computation engine. We numerically and experimentally showed the ability of the method to execute several different tasks with accuracy comparable to a digital implementation.

physics.optics↗

Optical Neural Networks: The 3D connection

We motivate a new canonical strategy for integrating photonic neural networks (NNs) by leveraging 3D printing. Our believe is that a NN's parallel and dense connectivity is not scalable without 3D integration. 3D additive fabrication complemented with photonic signal transduction can dramatically augment the current capabilities of 2D CMOS and integrated photonics. Here we review some of our recent advances made towards such a breakthrough architecture.

cs.ET↗

All-fiber spatiotemporally mode-locked laser with multimode fiber-based filtering

We demonstrate the first multimode fiber interference-based filtering in an all-fiber spatiotemporally mode-locked laser. The oscillator generates dissipative soliton pulses at 1036 nm with 12 mW average power, 6.24 ps duration and 24.3 MHz repetition rate. The reported pulse energy (0.5 nJ) represents ~4 times improvement over the previously reported single-mode all-normal dispersion mode-locked lasers with multimode interference-based filtering. Numerical simulations are performed to reveal cavity and spatiotemporal mode-locking dynamics. The proposed oscillator presents an alternative approach to achieve spatiotemporal mode-locking with an all-fiber design that can be fabricated simply.

physics.optics↗

Single mode output by controlling the spatiotemporal nonlinearities in mode-locked femtosecond multimode fiber lasers

The performance of fiber mode-locked lasers is limited due to the high nonlinearity induced by the spatial confinement of the single-mode fiber core. To massively increase the pulse energy of the femtosecond pulses, amplification is obtained outside the oscillator. Recently, spatiotemporal mode-locking has been proposed as a new path to fiber lasers. However, the beam quality was either highly multimode and/or with low pulse energy. Here we present an approach to reach high energy per pulse directly in the mode-locked multimode fiber oscillator with a near single-mode output beam. Our approach relies on spatial self-beam cleaning via the nonlinear Kerr effect and we demonstrate a multimode fiber oscillator with M2<1.13 beam profile, up to 24 nJ energy and sub-100 fs compressed duration. The reported approach is further power scalable with larger core sized fibers and could benefit applications that require high power ultrashort lasers with commercially available optical fibers.

physics.optics↗

Competing Neural Networks for Robust Control of Nonlinear Systems

The output of physical systems is often accessible by measurements such as the 3D position of a robotic arm actuated by many actuators or the speckle patterns formed by shining the spot of a laser pointer on a wall. The selection of the input of such a system (actuators and the shape of the laser spot respectively) to obtain a desired output is difficult because it is an ill-posed problem i.e. there are multiple inputs yielding the same output. In this paper, we propose an approach that provides a robust solution to this dilemma for any physical system. We show that it is possible to find the appropriate input of a system that results in a desired output, despite the input-output relation being nonlinear and\or with incomplete measurements of the systems variables. We showcase our approach using an extremely ill-posed problem in imaging. We demonstrate the projection of arbitrary shapes through a multimode fiber (MMF) when a sample of intensity-only measurements are taken at the output. We show image projection fidelity as high as ~90 %, which is on par with the gold standard methods which characterize the system fully by phase and amplitude measurements. The generality as well as simplicity of the proposed approach provides a new way of target-oriented control in real-world applications.

physics.optics↗

Three-Dimensional Optical Diffraction Tomography with Lippmann-Schwinger Model

A broad class of imaging modalities involve the resolution of an inverse-scattering problem. Among them, three-dimensional optical diffraction tomography (ODT) comes with its own challenges. These include a limited range of views, a large size of the sample with respect to the illumination wavelength, and optical aberrations that are inherent to the system itself. In this work, we present an accurate and efficient implementation of the forward model. It relies on the exact (nonlinear) Lippmann-Schwinger equation. We address several crucial issues such as the discretization of the Green function, the computation of the far field, and the estimation of the incident field. We then deploy this model in a regularized variational-reconstruction framework and show on both simulated and real data that it leads to substantially better reconstructions than the approximate models that are traditionally used in ODT.

eess.IV↗

Controlling spatiotemporal nonlinearities in multimode fibers with deep neural networks

Spatiotemporal nonlinear interactions in multimode fibers are of interest for beam shaping and frequency conversion by exploiting the nonlinear propagation of different pump regimes from quasi-continuous wave to ultrashort pulses centered around visible to infrared pump wavelengths. The nonlinear effects in multi-mode fibers depend strongly on the excitation condition, however relatively little work has been reported on this subject. Here, we present the first machine learning approach to learn and control the nonlinear frequency conversion inside multimode fibers by tailoring the excitation condition via deep neural networks. Trained with experimental data, deep neural networks are adapted to learn the relation between the spatial beam profile of the pump pulse and the spectrum generation. For different user-defined target spectra, network-suggested beam shapes are applied and control over the cascaded Raman scattering and supercontinuum generation processes are achieved. Our results present a novel method to tune the spectra of a broadband source.

physics.optics↗

Method for Assessing the Fidelity of Optical Diffraction Tomography Reconstruction Methods

We use a spatial light modulator in a diffraction tomographic system to assess the accuracy of different refractive index reconstruction algorithms. Optical phase conjugation principles through complex media, allows us to quantify the error for different refractive index reconstruction algorithms without access to the ground truth. To our knowledge, this is the first assessment technique that uses structured illumination experimentally to test the accuracy of different reconstruction schemes.

physics.optics↗

Spatiotemporal self-similar fiber laser

In this Letter, we demonstrate, to the best of our knowledge, the first spatiotemporally mode-locked fiber laser with self-similar pulse evolution. The multimode fiber oscillator generates parabolic amplifier similaritons at 1030 nm with 90 mW average power, 2.3 ps duration, and 37.9 MHz repetition rate. Remarkably, we observe experimentally a near-Gaussian beam quality (M^2<1.4) at the output of the highly multimode fiber. The output pulses are compressed to 192 fs via an external grating compressor. Numerical simulations are performed to investigate the cavity dynamics which confirm experimental observations of self-similar pulse propagation. The reported results open a new direction to investigate new types of pulse besides beam shaping and nonlinear dynamics in spatiotemporal mode-locked fiber lasers.

physics.optics↗

Deep-learning PDEs with unlabeled data and hardwiring physics laws

Providing fast and accurate solutions to partial differential equations is a problem of continuous interest to the fields of applied mathematics and physics. With the recent advances in machine learning, the adoption learning techniques in this domain is being eagerly pursued. We build upon earlier works on linear and homogeneous PDEs, and develop convolutional deep neural networks that can accurately solve nonlinear and non-homogeneous equations without the need for labeled data. The architecture of these networks is readily accessible for scientific disciplines who deal with PDEs and know the basics of deep learning.

physics.comp-ph↗

Multimode Optical Fiber Transmission with a Deep Learning Network

Multimode fibers (MMF) are an example of a highly scattering medium which scramble the coherent light propagating within them and produce seemingly random patterns. Thus, for applications such as imaging and image projection through a MMF, careful measurements of the relationship between inputs and outputs of the fiber are required. We show, as a proof of concept, that a deep learning neural network can learn the input-output relationship in a 0.75 m long MMF. Specifically, we demonstrate that a deep convolutional neural network (CNN) can learn the non-linear relationships between the amplitude of the speckle pattern obtained at the output of the fiber and the phase or amplitude at the input of the fiber. Effectively the network performs a non-linear inversion task. We obtained image fidelity (correlation) of ~98% compared with the image obtained using the measured matrix of the system. We further show that the network can be trained for transfer learning, i.e. it can transmit images through the MMF which belongs to another class which were not used for training/testing.

physics.optics↗

Learning to see through multimode fibers

We use Deep Neural Networks (DNNs) to classify and reconstruct a large database of handwritten digits from the intensity of the speckle patterns that result after the images propagated through multimode fibers (MMF). Images transmitted through fibers with up to 1km length were recovered. The ability of the network to recognize the input degraded with fiber length but the performance could be enhanced if the neural networks were trained to first reconstruct the image and then classify it rather than classify it directly from the speckle intensity.

physics.optics↗