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Dhruv D. Jatkar

Publications and source records attributed to Dhruv D. Jatkar.

3 recordsLinked to original sources

Convergence guarantees for Muon: New parameter regimes and generalizations

In this paper, we establish the first asymptotic convergence guarantees for the Muon algorithm through a more accurate proxy for the Newton-Schultz iteration than the typical matrix sign function. We prove that, for appropriate choices of hyperparameters, the iterates satisfy $\lim_{k\to\infty}\|\nabla f(x_k)\|=0$, and, under a global Polyak-Łojasiewicz condition, that the sequence of function values converges linearly. The key insight is that the regularization, implicit in Muon's Newton-Schulz implementation, induces a bounded preconditioner, exposing Muon as a \emph{preconditioned Polyak heavy-ball} method and enabling a classical Lyapunov analysis. This observation naturally motivates applying the same preconditioning structure to the Nesterov gradient evaluation. We formalize this idea by introducing \emph{Muesterov}, a Nesterov-based variant of Muon, and prove that it enjoys the same convergence guarantees, extending the theoretical framework beyond the heavy-ball setting. Numerical experiments on a scalar cross-entropy problem corroborate the theory and illuminate the joint role of the learning rate and the Newton-Schulz regularizer in controlling convergence. Preliminary numerical simulations training the nanoGPT dataset provide intuition regarding the relevance of the observations in this paper to practical applications.

math.NA↗

Interplay between Contractivity and Monotonicity for Reaction Networks

We establish a new relationship between monotonicity and contractivity and use this connection to describe a new general class of weakly contractive reaction networks. The new class is characterized by the stoichiometry matrix of the reaction network admitting a precise matrix factorization that can be verified computationally. Reaction networks in this class are weakly contractive, implying global convergence to equilibria under appropriate technical conditions. Furthermore, we describe the novel subclass of cross-polytope networks. We also show that our results provide a unified proof of global convergence for several classes of networks previously studied in the literature. The practical relevance of the results is demonstrated by examples from systems biology and signaling pathways.

math.DS↗

Competition for binding targets results in paradoxical effects for simultaneous activator and repressor action -- Extended Version

In the context of epigenetic transformations in cancer metastasis, a puzzling effect was recently discovered, in which the elimination (knock-out) of an activating regulatory element leads to increased (rather than decreased) activity of the element being regulated. It has been postulated that this paradoxical behavior can be explained by activating and repressing transcription factors competing for binding to other possible targets. It is very difficult to prove this hypothesis in mammalian cells, due to the large number of potential players and the complexity of endogenous intracellular regulatory networks. Instead, this paper analyzes this issue through an analogous synthetic biology construct which aims to reproduce the paradoxical behavior using standard bacterial gene expression networks. The paper first reviews the motivating cancer biology work, and then describes a proposed synthetic construct. A mathematical model is formulated, and basic properties of uniqueness of steady states and convergence to equilibria are established, as well as an identification of parameter regimes which should lead to observing such paradoxical phenomena (more activator leads to less activity at steady state). A proof is also given to show that this is a steady-state property, and for initial transients the phenomenon will not be observed. This work adds to the general line of work of resource competition in synthetic circuits.

q-bio.MN↗