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Diego Paez-Granados

Publications and source records attributed to Diego Paez-Granados.

At least 19 recordsLinked to original sources

ECGLight: Compute-Light Framework For Paper ECG Digitization and Myocardial Infarction Screening

Electrocardiography (ECG) is one of the most widely used tests for diagnosing cardiovascular disease. Yet several remote clinics still utilize paper ECG printouts for their analysis due to limited connectivity and computational capacity. As a result, vast numbers of physical ECGs obtained in remote areas still remain incapable of being accessed by contemporary artificial-intelligence (AI)-based decision support as they require high computational resources or strong high-speed internet connectivity. This causes several cases where conditions like acute coronary occlusion (ACS) is overlooked and reperfusion therapy delayed. Although prior work has tackled digitization and diagnosis separately, and utilized advanced AI models for them, there still remains a lack of a compute-light, on-device framework that reconstructs paper ECGs at high fidelity, while accurately supporting multiple clinically relevant endpoints. We address this need with an end-to-end lightweight on-device digitization-to-diagnosis pipeline that converts a smartphone photo or scan of a paper ECG into a calibrated 12-lead signal and screens for Myocardial Infarction (MI) pathologies, with SHapley Additive exPlanations (SHAP) to support interpretability. Trained and evaluated on 21,799 ECGs from the PTB-XL dataset and further validated on hospital-acquired ECG-Matrix dataset, the complete system runs in <30 s per ECG on CPU-only resources, achieving 95.51% accuracy (F1 = 0.9519) for MI detection on PTB-XL and 88.89% accuracy (F1 = 0.8862) for OMI detection on ECG-Matrix. This work showcases that legacy paper records can be reliably democratized in any part of the world, providing a scalable decision support when digital ECG export, connectivity, or high-end compute are unavailable. Github: https://github.com/nshreyasvi/ECGLight

cs.LG↗

Monocular markerless biomechanics for clinically interpretable gait assessment in spinal cord injury

Three-dimensional gait analysis guides rehabilitation after spinal cord injury but depends on marker-based motion capture and force plates, which few clinics have. Monocular markerless pipelines have been established in fewer healthy adult cohorts but not in neurological cohorts. We present the SCAI SCI Gait dataset, comprising 239 adult individuals with spinal cord injury with synchronized video, motion capture, and force-plate measurements, we fitted a parametric body mesh to a single sagittal-view video, driving an anthropometrically scaled OpenSim model via virtual markers. Markerless lower-body kinematics showed state-of-the-art agreement with motion-capture measurements (r = 0.68-0.90, p < 0.001, and RMSE = 4.18-6.49 degrees), and accurate kinematics-based predicted ground-reaction forces closely matched those measured by force plates (r = 0.85-0.87, p < 0.001, and RMSE = 2.13-2.19 Newton per kg). Furthermore, conditional-dependence graph analysis with Markov blankets revealed that waveform components were conditionally associated with functional independence, and speed-stratified clustering revealed distinct mechanical strategies among individuals walking at similar speeds. These findings establish the use of monocular video as a scalable approach for clinically meaningful biomechanical assessment and data-driven phenotyping in patients with spinal cord injury. Github: https://github.com/SCAI-Lab/SCAI-SCI-Gait-Dataset

cs.CV↗

Beyond Leaderboard Scores: A Deployment-Focused Protocol for Interpretable Tracking Evaluation in Pedestrian-Centric Environments

Mobile robots operating among pedestrians need trajectories that become available quickly, remain spatially credible through missed observations, preserve identity, and fit within an embedded computing budget. Aggregate tracking scores provide limited insight into when and how trajectories fail, while varying detector inputs can confound tracker and detector quality. We present a deployment-focused, tracker-only evaluation protocol that uses shared detections to isolate tracker behavior and directly evaluates initialization, detector-gap continuation, identity recovery, close-neighbor association, and load-dependent tracker-step runtime, while Higher Order Tracking Accuracy (HOTA) is retained as a complementary aggregate measure. We apply the protocol to the JackRabbot Dataset and Benchmark (JRDB) using six open-source trackers and our lightweight Pedestrian Reference Tracker (PedRefTrack), together with a GT-assisted variant that estimates the remaining tracker-side gap under idealized association and motion. Under fixed detections, the non-GT trackers span only 24.26%-29.67% HOTA yet exhibit markedly different capability profiles. After 1.0 s without detector support, no tracker without GT assistance maintains spatially correct, same-identity output in more than half of eligible cases, making missing-observation continuation the dominant limitation among the tested properties. Close-neighbor failures are smaller and increase mainly at the shortest separations. Tracker-step runtime on an NVIDIA Jetson Orin is heavy-tailed and load-sensitive, causing several trackers to fall below the 10 Hz real-time target in crowded frames. The protocol provides a reproducible way to characterize tracker behavior and deployment suitability in pedestrian-centric environments. Code and evaluation scripts are released at https://github.com/SCAI-Lab/tracker_eval.

cs.RO↗

GARLIC: Graph Attention-based Relational Learning of Multivariate Time Series in Intensive Care

Healthcare data, such as Intensive Care Unit (ICU) records, comprise heterogeneous multivariate time series sampled at irregular intervals with pervasive missingness. However, clinical applications demand predictive models that are both accurate and interpretable. We present our Graph Attention-based Relational Learning for Intensive Care (GARLIC) model, a novel neural network architecture that imputes missing data through a learnable exponential-decay encoder, captures inter-sensor dependencies via time-lagged summary graphs, and fuses global patterns with cross-dimensional sequential attention. All attention weights and graph edges are learned end-to-end to serve as built-in observation-, signal-, and edge-level explanations. To reconcile auxiliary reconstruction and primary classification objectives, we developed an alternating decoupled optimization scheme that stabilizes training. On three ICU benchmarks (PhysioNet 2012 & 2019, MIMIC-III), GARLIC sets the new state of the art in outcome prediction, significantly improving AUROC and AUPRC over best-performing baselines at comparable computational cost. Ablation studies confirm the contribution of each module, and feature-removal trials validate the fidelity of importance attribution through a monotonic performance drop (full > top 50% > random 50% > bottom 50%). Real-time case studies demonstrate actionable risk warnings with transparent explanations, marking a significant advance toward accurate, explainable deep learning for irregularly sampled ICU time series data. Moreover, we demonstrated \proposed{}'s superiority in data imputation and classification on various time-series datasets beyond the ICU domain, showing its generalizability and applicability to broader tasks.

cs.LG↗

On the Role of Inductive Bias in Time-Series Pretraining: A Case Study in Learning Generalizable Representations for Clinical Time Series

Clinical time-series learning is routinely constrained by small, heterogeneous cohorts and protocol drift, while its downstream use spans both classification (e.g., pathology diagnosis) and regression (e.g., temporal forecasting). These constraints make foundation-model pretraining appealing, but raises an important question of which inductive biases should the pretraining objective impose so that representations transfer across task types and subjects. We study this question in pathological gait analysis for spinal cord injury (SCI) via PathoFM, an encoder-centric transformer pretrained on multivariate gait windows with three complementary objectives: Local Completion (reconstruct contiguous masked spans to enforce local structure), Temporal Continuity (predict a masked mid-horizon continuation from an observed prefix to enforce smoothness and causal consistency), and Unsupervised In-Context Dynamics (support-query reconstruction conditioned on subject exemplar windows via attention). Empirically comparing objective families (grouping/contrastive, dynamics-based, and generative reconstruction), we find that dynamics-centric mixtures produce the most balanced transfer: grouping objectives favor discriminative margins but can degrade magnitude fidelity needed for continuous targets, whereas reconstruction-only objectives preserve waveform structure but may underperform on classification. Overall, combining local reconstruction with temporal continuity, and adding in-context conditioning when exemplar access is realistic, yields robust subject-generalizing representations.

cs.LG↗

User Involvement in Robotic Wheelchair Development: A Decade of Limited Progress

Robotic wheelchairs (RWs) offer significant potential to enhance autonomy and participation for people with mobility impairments, yet many systems have failed to achieve sustained real-world adoption. This narrative literature review examined the extent and quality of end-user involvement in RW design, development, and evaluation over the past decade (2015--2025), assessed against core principles shared by major user-involvement approaches (e.g., user-/human-centered design, participatory/co-design, and inclusive design). The findings indicate that user involvement remains limited and is predominantly concentrated in late-stage evaluation rather than in early requirements definition or iterative co-design. Of the 399 records screened, only 23 studies (about 6%) met the inclusion criteria of verifiable end-user involvement, and many relied on small samples, often around ten participants, with limited justification for sample size selection, proxy users, laboratory-based validation, and non-standardized feedback methods. Research teams were largely engineering-dominated (about 89%) and geographically concentrated in high-income countries. Despite strong evidence that sustained user engagement improves usability and adoption in assistive technology, its systematic implementation in RW research remains rare. Advancing the field requires embedding participatory methodologies throughout the design lifecycle and addressing systemic barriers that constrain meaningful user involvement.

cs.HC↗

A learning health system in Neurorehabilitation as a foundation for multimodal patient representation

Neurological disorders represent a growing global health burden requiring long-term, interdisciplinary rehabilitation. Computational neurorehabilitation (compNR) - the use of data-driven and model-based approaches to personalize treatment - offers new opportunities for precision rehabilitation. However, its clinical deployment is limited by fragmented data systems, poor interoperability, and low clinician engagement in model development. We embed the learning health system (LHS) framework in Neurorehabilitation through integration of multimodal data collection, model computation, and clinical visualization that enables clinician-ML collaboration in everyday neurorehabilitation practice. The system facilitates structured digital data capture, secure computational processing, and interoperable visualization of patient trajectories. Through a real-world deployment in stroke rehabilitation, we demonstrate how such an infrastructure bridges the gap between research models and clinical use, showcasing one approach to a translational pathway for compNR.

cs.HC↗

FedSCS-XGB -- Federated Server-centric surrogate XGBoost for continual health monitoring

Wearable sensors with local data processing can detect health threats early, enhance documentation, and support personalized therapy. In the context of spinal cord injury (SCI), which involves risks such as pressure injuries and blood pressure instability, continuous monitoring can help mitigate these by enabling early deDtection and intervention. In this work, we present a novel distributed machine learning (DML) protocol for human activity recognition (HAR) from wearable sensor data based on gradient-boosted decision trees (XGBoost). The proposed architecture is inspired by Party-Adaptive XGBoost (PAX) while explicitly preserving key structural and optimization properties of standard XGBoost, including histogram-based split construction and tree-ensemble dynamics. First, we provide a theoretical analysis showing that, under appropriate data conditions and suitable hyperparameter selection, the proposed distributed protocol can converge to solutions equivalent to centralized XGBoost training. Second, the protocol is empirically evaluated on a representative wearable-sensor HAR dataset, reflecting the heterogeneity and data fragmentation typical of remote monitoring scenarios. Benchmarking against centralized XGBoost and IBM PAX demonstrates that the theoretical convergence properties are reflected in practice. The results indicate that the proposed approach can match centralized performance up to a gap under 1\% while retaining the structural advantages of XGBoost in distributed wearable-based HAR settings.

cs.LG↗

KarmaTS: A Universal Simulation Platform for Multivariate Time Series with Functional Causal Dynamics

We introduce KarmaTS, an interactive framework for constructing lag-indexed, executable spatiotemporal causal graphical models for multivariate time series (MTS) simulation. Motivated by the challenge of access-restricted physiological data, KarmaTS generates synthetic MTS with known causal dynamics and augments real-world datasets with expert knowledge. The system constructs a discrete-time structural causal process (DSCP) by combining expert knowledge and algorithmic proposals in a mixed-initiative, human-in-the-loop workflow. The resulting DSCP supports simulation and causal interventions, including those under user-specified distribution shifts. KarmaTS handles mixed variable types, contemporaneous and lagged edges, and modular edge functionals ranging from parameterizable templates to neural network models. Together, these features enable flexible validation and benchmarking of causal discovery algorithms through expert-informed simulation.

cs.AI↗

Detection of Autonomic Dysreflexia in Individuals With Spinal Cord Injury Using Multimodal Wearable Sensors

Autonomic Dysreflexia (AD) is a potentially life-threatening condition characterized by sudden, severe blood pressure (BP) spikes in individuals with spinal cord injury (SCI). Early, accurate detection is essential to prevent cardiovascular complications, yet current monitoring methods are either invasive or rely on subjective symptom reporting, limiting applicability in daily file. This study presents a non-invasive, explainable machine learning framework for detecting AD using multimodal wearable sensors. Data were collected from 27 individuals with chronic SCI during urodynamic studies, including electrocardiography (ECG), photoplethysmography (PPG), bioimpedance (BioZ), temperature, respiratory rate (RR), and heart rate (HR), across three commercial devices. Objective AD labels were derived from synchronized cuff-based BP measurements. Following signal preprocessing and feature extraction, BorutaSHAP was used for robust feature selection, and SHAP values for explainability. We trained modality- and device-specific weak learners and aggregated them using a stacked ensemble meta-model. Cross-validation was stratified by participants to ensure generalizability. HR- and ECG-derived features were identified as the most informative, particularly those capturing rhythm morphology and variability. The Nearest Centroid ensemble yielded the highest performance (Macro F1 = 0.77+/-0.03), significantly outperforming baseline models. Among modalities, HR achieved the highest area under the curve (AUC = 0.93), followed by ECG (0.88) and PPG (0.86). RR and temperature features contributed less to overall accuracy, consistent with missing data and low specificity. The model proved robust to sensor dropout and aligned well with clinical AD events. These results represent an important step toward personalized, real-time monitoring for individuals with SCI.

eess.SP↗

Shared Control of Holonomic Wheelchairs through Reinforcement Learning

Smart electric wheelchairs can improve user experience by supporting the driver with shared control. State-of-the-art work showed the potential of shared control in improving safety in navigation for non-holonomic robots. However, for holonomic systems, current approaches often lead to unintuitive behavior for the user and fail to utilize the full potential of omnidirectional driving. Therefore, we propose a reinforcement learning-based method, which takes a 2D user input and outputs a 3D motion while ensuring user comfort and reducing cognitive load on the driver. Our approach is trained in Isaac Gym and tested in simulation in Gazebo. We compare different RL agent architectures and reward functions based on metrics considering cognitive load and user comfort. We show that our method ensures collision-free navigation while smartly orienting the wheelchair and showing better or competitive smoothness compared to a previous non-learning-based method. We further perform a sim-to-real transfer and demonstrate, to the best of our knowledge, the first real-world implementation of RL-based shared control for an omnidirectional mobility platform.

cs.RO↗

Embedding computational neurorehabilitation in clinical practice using a modular intelligent health system

A significant and rising proportion of the global population suffer from non-communicable diseases, such as neurological disorders. Neurorehabilitation aims to restore function and independence of neurological patients through providing interdisciplinary therapeutic interventions. Computational neurorehabilitation, an automated simulation approach to dynamically optimize treatment effectivity, is a promising tool to ensure that each patient has the best therapy for their current status. However, computational neurorehabilitation relies on integrated data flows between clinical assessments, predictive models, and healthcare professionals. Current neurorehabilitation practice is limited by low levels of digitalization and low data interoperability. We here propose and demonstrate an embedded intelligent health system that enables detailed digital data collection in a modular fashion, real-time data flows between patients, models, and clinicians, clinical integration, and multi-context capacities, as required for computational neurorehabilitation approaches. We give an outlook on how modern exploratory data analysis tools can be integrated to facilitate model development and knowledge inference from secondary use of observational data this system collects. With this blueprint, we contribute towards the development of integrated computational neurorehabilitation workflows for clinical practice.

cs.SE↗

Sim-to-Real Transfer for Mobile Robots with Reinforcement Learning: from NVIDIA Isaac Sim to Gazebo and Real ROS 2 Robots

Unprecedented agility and dexterous manipulation have been demonstrated with controllers based on deep reinforcement learning (RL), with a significant impact on legged and humanoid robots. Modern tooling and simulation platforms, such as NVIDIA Isaac Sim, have been enabling such advances. This article focuses on demonstrating the applications of Isaac in local planning and obstacle avoidance as one of the most fundamental ways in which a mobile robot interacts with its environments. Although there is extensive research on proprioception-based RL policies, the article highlights less standardized and reproducible approaches to exteroception. At the same time, the article aims to provide a base framework for end-to-end local navigation policies and how a custom robot can be trained in such simulation environment. We benchmark end-to-end policies with the state-of-the-art Nav2, navigation stack in Robot Operating System (ROS). We also cover the sim-to-real transfer process by demonstrating zero-shot transferability of policies trained in the Isaac simulator to real-world robots. This is further evidenced by the tests with different simulated robots, which show the generalization of the learned policy. Finally, the benchmarks demonstrate comparable performance to Nav2, opening the door to quick deployment of state-of-the-art end-to-end local planners for custom robot platforms, but importantly furthering the possibilities by expanding the state and action spaces or task definitions for more complex missions. Overall, with this article we introduce the most important steps, and aspects to consider, in deploying RL policies for local path planning and obstacle avoidance with Isaac Sim training, Gazebo testing, and ROS 2 for real-time inference in real robots. The code is available at https://github.com/sahars93/RL-Navigation.

cs.RO↗

Torso-Based Control Interface for Standing Mobility-Assistive Devices

Wheelchairs and mobility devices have transformed our bodies into cybernic systems, enhancing our well-being by enabling individuals with reduced mobility to regain freedom. Notwithstanding, current interfaces of control primarily rely on hand operation, therefore constraining the user from performing functional activities of daily living. In this work, we propose a design of a torso-based control interface with compliant coupling support for standing mobility assistive devices. We consider the coupling between the human and robot in the interface design. The design includes a compliant support mechanism and mapping between the body movement space and the velocity space. We present experiments including multiple conditions, with a joystick for comparison with the proposed torso control interface. The results of a path-following experiment demonstrated that users could control the device naturally using the hands-free interface, and the performance was comparable with the joystick, with 10% more consumed time, an average cross error of 0.116 m and 4.9% less average acceleration. In an object-transferring experiment, the proposed interface demonstrated a clear advantage when users needed to manipulate objects during locomotion. Lastly, the torso control scored 15% less than the joystick on the system usability scale for the path-following task but 3.3% more for the object-transferring task.

cs.RO↗

Pedestrian-Robot Interactions on Autonomous Crowd Navigation: Reactive Control Methods and Evaluation Metrics

Autonomous navigation in highly populated areas remains a challenging task for robots because of the difficulty in guaranteeing safe interactions with pedestrians in unstructured situations. In this work, we present a crowd navigation control framework that delivers continuous obstacle avoidance and post-contact control evaluated on an autonomous personal mobility vehicle. We propose evaluation metrics for accounting efficiency, controller response and crowd interactions in natural crowds. We report the results of over 110 trials in different crowd types: sparse, flows, and mixed traffic, with low- (< 0.15 ppsm), mid- (< 0.65 ppsm), and high- (< 1 ppsm) pedestrian densities. We present comparative results between two low-level obstacle avoidance methods and a baseline of shared control. Results show a 10% drop in relative time to goal on the highest density tests, and no other efficiency metric decrease. Moreover, autonomous navigation showed to be comparable to shared-control navigation with a lower relative jerk and significantly higher fluency in commands indicating high compatibility with the crowd. We conclude that the reactive controller fulfils a necessary task of fast and continuous adaptation to crowd navigation, and it should be coupled with high-level planners for environmental and situational awareness.

cs.RO↗

Unfreezing Social Navigation: Dynamical Systems based Compliance for Contact Control in Robot Navigation

Large efforts have focused on ensuring that the controllers for mobile service robots follow proxemics and other social rules to ensure both safe and socially acceptable distance to pedestrians. Nonetheless, involuntary contact may be unavoidable when the robot travels in crowded areas or when encountering adversarial pedestrians. Freezing the robot in response to contact might be detrimental to bystanders' safety and prevents it from achieving its task. Unavoidable contacts must hence be controlled to ensure the safe and smooth travelling of robots in pedestrian alleys. We present a force-limited and obstacle avoidance controller integrated into a time-invariant dynamical system (DS) in a closed-loop force controller that let the robot react instantaneously to contact or to the sudden appearance of pedestrians. Mitigating the risk of collision is done by modulating the velocity commands upon detecting a contact and by absorbing part of the contact force through active compliant control when the robot bumps inadvertently against a pedestrian. We evaluated our method with a personal mobility robot -- Qolo -- showing contact mitigation with passive and active compliance. We showed the robot able to overcome an adversarial pedestrian within 9 N of the set limit contact force for speeds under 1 m/s. Moreover, we evaluated integrated obstacle avoidance proving the ability to advance without incurring any other collision.

cs.RO↗

Personal Mobility With Synchronous Trunk-Knee Passive Exoskeleton: Optimizing Human-Robot Energy Transfer

We present a personal mobility device for lower-body impaired users through a light-weighted exoskeleton on wheels. On its core, a novel passive exoskeleton provides postural transition leveraging natural body postures with support to the trunk on sit-to-stand and stand-to-sit (STS) transitions by a single gas spring as an energy storage unit. We propose a direction-dependent coupling of knees and hip joints through a double-pulley wire system, transferring energy from the torso motion towards balancing the moment load at the knee joint actuator. Herewith, the exoskeleton maximizes energy transfer and the naturalness of the user's movement. We introduce an embodied user interface for hands-free navigation through a torso pressure sensing with minimal trunk rotations, resulting on average $19^{\circ} \pm 13^{\circ}$ on six unimpaired users. We evaluated the design for STS assistance on 11 unimpaired users observing motions and muscle activity during the transitions. Results comparing assisted and unassisted STS transitions validated a significant reduction (up to $68\%$ $p<0.01$) at the involved muscle groups. Moreover, we showed it feasible through natural torso leaning movements of $+12^{\circ}\pm 6.5^{\circ}$ and $- 13.7^{\circ} \pm 6.1^{\circ}$ for standing and sitting, respectively. Passive postural transition assistance warrants further work on increasing its applicability and broadening the user population.

cs.RO↗

Virtual Landmark-Based Control of Docking Support for Assistive Mobility Devices

This work proposes an autonomous docking control for nonholonomic constrained mobile robots and applies it to an intelligent mobility device or wheelchair for assisting the user in approaching resting furniture such as a chair or a bed. We defined a virtual landmark inferred from the target docking destination. Then, we solve the problem of keeping the targeted volume inside the field of view (FOV) of a tracking camera and docking to the virtual landmark through a novel definition that enables to control for the desired end-pose. In this article, we proposed a nonlinear feedback controller to perform the docking with the depth camera's FOV as a constraint. Then, a numerical method is proposed to find the feasible space of initial states where convergence could be guaranteed. Finally, the entire system was embedded for real-time operation on a standing wheelchair with the virtual landmark estimation by 3D object tracking with an RGB-D camera and we validated the effectiveness in simulation and experimental evaluations. The results show the guaranteed convergence for the feasible space depending on the virtual landmark location. In the implementation, the robot converges to the virtual landmark while respecting the FOV constraints.

cs.RO↗