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Dimitri Yatsenko

Publications and source records attributed to Dimitri Yatsenko.

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DataJoint 2.0: A Computational Substrate for Agentic Scientific Workflows

Operational rigor determines whether human-agent collaboration succeeds or fails. Scientific data pipelines need the equivalent of DevOps -- SciOps -- yet common approaches fragment provenance across disconnected systems without transactional guarantees. DataJoint 2.0 addresses this gap through the relational workflow model: tables represent workflow steps, rows represent artifacts, foreign keys prescribe execution order. The schema specifies not only what data exists but how it is derived -- a single formal system where data structure, computational dependencies, and integrity constraints are all queryable, enforceable, and machine-readable. Four technical innovations extend this foundation: object-augmented schemas integrating relational metadata with scalable object storage, semantic matching using attribute lineage to prevent erroneous joins, an extensible type system for domain-specific formats, and distributed job coordination designed for composability with external orchestration. By unifying data structure, data, and computational transformations, DataJoint creates a substrate for SciOps where agents can participate in scientific workflows without risking data corruption.

cs.DB

SciOps: Achieving Productivity and Reliability in Data-Intensive Research

Scientists are increasingly leveraging advances in instruments, automation, and collaborative tools to scale up their experiments and research goals, leading to new bursts of discovery. Various scientific disciplines, including neuroscience, have adopted key technologies to enhance collaboration, reproducibility, and automation. Drawing inspiration from advancements in the software industry, we present a roadmap to enhance the reliability and scalability of scientific operations for diverse research teams tackling large and complex projects. We introduce a five-level Capability Maturity Model describing the principles of rigorous scientific operations in projects ranging from small-scale exploratory studies to large-scale, multi-disciplinary research endeavors. Achieving higher levels of operational maturity necessitates the adoption of new, technology-enabled methodologies, which we refer to as SciOps. This concept is derived from the DevOps methodologies that have revolutionized the software industry. SciOps involves digital research environments that seamlessly integrate computational, automation, and AI-driven efforts throughout the research cycle-from experimental design and data collection to analysis and dissemination, ultimately leading to closed-loop discovery. This maturity model offers a framework for assessing and improving operational practices in multidisciplinary research teams, guiding them towards greater efficiency and effectiveness in scientific inquiry.

q-bio.NC

DataJoint: A Simpler Relational Data Model

The relational data model offers unrivaled rigor and precision in defining data structure and querying complex data. Yet the use of relational databases in scientific data pipelines is limited due to their perceived unwieldiness. We propose a simplified and conceptually refined relational data model named DataJoint. The model includes a language for schema definition, a language for data queries, and diagramming notation for visualizing entities and relationships among them. The model adheres to the principle of entity normalization, which requires that all data -- both stored and derived -- must be represented by well-formed entity sets. DataJoint's data query language is an algebra on entity sets with five operators that provide matching capabilities to those of other relational query languages with greater clarity due to entity normalization. Practical implementations of DataJoint have been adopted in neuroscience labs for fluent interaction with scientific data pipelines.

cs.DB