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Dimitris Metaxas

Publications and source records attributed to Dimitris Metaxas.

At least 37 records · Page 2Linked to original sources

SnapGen-V: Generating a Five-Second Video within Five Seconds on a Mobile Device

We have witnessed the unprecedented success of diffusion-based video generation over the past year. Recently proposed models from the community have wielded the power to generate cinematic and high-resolution videos with smooth motions from arbitrary input prompts. However, as a supertask of image generation, video generation models require more computation and are thus hosted mostly on cloud servers, limiting broader adoption among content creators. In this work, we propose a comprehensive acceleration framework to bring the power of the large-scale video diffusion model to the hands of edge users. From the network architecture scope, we initialize from a compact image backbone and search out the design and arrangement of temporal layers to maximize hardware efficiency. In addition, we propose a dedicated adversarial fine-tuning algorithm for our efficient model and reduce the denoising steps to 4. Our model, with only 0.6B parameters, can generate a 5-second video on an iPhone 16 PM within 5 seconds. Compared to server-side models that take minutes on powerful GPUs to generate a single video, we accelerate the generation by magnitudes while delivering on-par quality.

cs.CV↗

DiMSUM: Diffusion Mamba -- A Scalable and Unified Spatial-Frequency Method for Image Generation

We introduce a novel state-space architecture for diffusion models, effectively harnessing spatial and frequency information to enhance the inductive bias towards local features in input images for image generation tasks. While state-space networks, including Mamba, a revolutionary advancement in recurrent neural networks, typically scan input sequences from left to right, they face difficulties in designing effective scanning strategies, especially in the processing of image data. Our method demonstrates that integrating wavelet transformation into Mamba enhances the local structure awareness of visual inputs and better captures long-range relations of frequencies by disentangling them into wavelet subbands, representing both low- and high-frequency components. These wavelet-based outputs are then processed and seamlessly fused with the original Mamba outputs through a cross-attention fusion layer, combining both spatial and frequency information to optimize the order awareness of state-space models which is essential for the details and overall quality of image generation. Besides, we introduce a globally-shared transformer to supercharge the performance of Mamba, harnessing its exceptional power to capture global relationships. Through extensive experiments on standard benchmarks, our method demonstrates superior results compared to DiT and DIFFUSSM, achieving faster training convergence and delivering high-quality outputs. The codes and pretrained models are released at https://github.com/VinAIResearch/DiMSUM.git.

cs.CV↗

SINE: SINgle Image Editing with Text-to-Image Diffusion Models

Recent works on diffusion models have demonstrated a strong capability for conditioning image generation, e.g., text-guided image synthesis. Such success inspires many efforts trying to use large-scale pre-trained diffusion models for tackling a challenging problem--real image editing. Works conducted in this area learn a unique textual token corresponding to several images containing the same object. However, under many circumstances, only one image is available, such as the painting of the Girl with a Pearl Earring. Using existing works on fine-tuning the pre-trained diffusion models with a single image causes severe overfitting issues. The information leakage from the pre-trained diffusion models makes editing can not keep the same content as the given image while creating new features depicted by the language guidance. This work aims to address the problem of single-image editing. We propose a novel model-based guidance built upon the classifier-free guidance so that the knowledge from the model trained on a single image can be distilled into the pre-trained diffusion model, enabling content creation even with one given image. Additionally, we propose a patch-based fine-tuning that can effectively help the model generate images of arbitrary resolution. We provide extensive experiments to validate the design choices of our approach and show promising editing capabilities, including changing style, content addition, and object manipulation. The code is available for research purposes at https://github.com/zhang-zx/SINE.git .

cs.CV↗

Improved Training Technique for Latent Consistency Models

Consistency models are a new family of generative models capable of producing high-quality samples in either a single step or multiple steps. Recently, consistency models have demonstrated impressive performance, achieving results on par with diffusion models in the pixel space. However, the success of scaling consistency training to large-scale datasets, particularly for text-to-image and video generation tasks, is determined by performance in the latent space. In this work, we analyze the statistical differences between pixel and latent spaces, discovering that latent data often contains highly impulsive outliers, which significantly degrade the performance of iCT in the latent space. To address this, we replace Pseudo-Huber losses with Cauchy losses, effectively mitigating the impact of outliers. Additionally, we introduce a diffusion loss at early timesteps and employ optimal transport (OT) coupling to further enhance performance. Lastly, we introduce the adaptive scaling-$c$ scheduler to manage the robust training process and adopt Non-scaling LayerNorm in the architecture to better capture the statistics of the features and reduce outlier impact. With these strategies, we successfully train latent consistency models capable of high-quality sampling with one or two steps, significantly narrowing the performance gap between latent consistency and diffusion models. The implementation is released here: https://github.com/quandao10/sLCT/

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MedForge: Building Medical Foundation Models Like Open Source Software Development

Foundational models (FMs) have made significant strides in the healthcare domain. Yet the data silo challenge and privacy concern remain in healthcare systems, hindering safe medical data sharing and collaborative model development among institutions. The collection and curation of scalable clinical datasets increasingly become the bottleneck for training strong FMs. In this study, we propose Medical Foundation Models Merging (MedForge), a cooperative framework enabling a community-driven medical foundation model development, meanwhile preventing the information leakage of raw patient data and mitigating synchronization model development issues across clinical institutions. MedForge offers a bottom-up model construction mechanism by flexibly merging task-specific Low-Rank Adaptation (LoRA) modules, which can adapt to downstream tasks while retaining original model parameters. Through an asynchronous LoRA module integration scheme, the resulting composite model can progressively enhance its comprehensive performance on various clinical tasks. MedForge shows strong performance on multiple clinical datasets (e.g., breast cancer, lung cancer, and colon cancer) collected from different institutions. Our major findings highlight the value of collaborative foundation models in advancing multi-center clinical collaboration effectively and cohesively. Our code is publicly available at https://github.com/TanZheling/MedForge.

cs.LG↗

BLoB: Bayesian Low-Rank Adaptation by Backpropagation for Large Language Models

Large Language Models (LLMs) often suffer from overconfidence during inference, particularly when adapted to downstream domain-specific tasks with limited data. Previous work addresses this issue by employing approximate Bayesian estimation after the LLMs are trained, enabling them to quantify uncertainty. However, such post-training approaches' performance is severely limited by the parameters learned during training. In this paper, we go beyond post-training Bayesianization and propose Bayesian Low-Rank Adaptation by Backpropagation (BLoB), an algorithm that continuously and jointly adjusts both the mean and covariance of LLM parameters throughout the whole fine-tuning process. Our empirical results verify the effectiveness of BLoB in terms of generalization and uncertainty estimation, when evaluated on both in-distribution and out-of-distribution data.

cs.LG↗

Rate-My-LoRA: Efficient and Adaptive Federated Model Tuning for Cardiac MRI Segmentation

Cardiovascular disease (CVD) and cardiac dyssynchrony are major public health problems in the United States. Precise cardiac image segmentation is crucial for extracting quantitative measures that help categorize cardiac dyssynchrony. However, achieving high accuracy often depends on centralizing large datasets from different hospitals, which can be challenging due to privacy concerns. To solve this problem, Federated Learning (FL) is proposed to enable decentralized model training on such data without exchanging sensitive information. However, bandwidth limitations and data heterogeneity remain as significant challenges in conventional FL algorithms. In this paper, we propose a novel efficient and adaptive federate learning method for cardiac segmentation that improves model performance while reducing the bandwidth requirement. Our method leverages the low-rank adaptation (LoRA) to regularize model weight update and reduce communication overhead. We also propose a \mymethod{} aggregation technique to address data heterogeneity among clients. This technique adaptively penalizes the aggregated weights from different clients by comparing the validation accuracy in each client, allowing better generalization performance and fast local adaptation. In-client and cross-client evaluations on public cardiac MR datasets demonstrate the superiority of our method over other LoRA-based federate learning approaches.

cs.CV↗

VerSe: Integrating Multiple Queries as Prompts for Versatile Cardiac MRI Segmentation

Despite the advances in learning-based image segmentation approach, the accurate segmentation of cardiac structures from magnetic resonance imaging (MRI) remains a critical challenge. While existing automatic segmentation methods have shown promise, they still require extensive manual corrections of the segmentation results by human experts, particularly in complex regions such as the basal and apical parts of the heart. Recent efforts have been made on developing interactive image segmentation methods that enable human-in-the-loop learning. However, they are semi-automatic and inefficient, due to their reliance on click-based prompts, especially for 3D cardiac MRI volumes. To address these limitations, we propose VerSe, a Versatile Segmentation framework to unify automatic and interactive segmentation through mutiple queries. Our key innovation lies in the joint learning of object and click queries as prompts for a shared segmentation backbone. VerSe supports both fully automatic segmentation, through object queries, and interactive mask refinement, by providing click queries when needed. With the proposed integrated prompting scheme, VerSe demonstrates significant improvement in performance and efficiency over existing methods, on both cardiac MRI and out-of-distribution medical imaging datasets. The code is available at https://github.com/bangwayne/Verse.

cs.CV↗

Learning Volumetric Neural Deformable Models to Recover 3D Regional Heart Wall Motion from Multi-Planar Tagged MRI

Multi-planar tagged MRI is the gold standard for regional heart wall motion evaluation. However, accurate recovery of the 3D true heart wall motion from a set of 2D apparent motion cues is challenging, due to incomplete sampling of the true motion and difficulty in information fusion from apparent motion cues observed on multiple imaging planes. To solve these challenges, we introduce a novel class of volumetric neural deformable models ($\upsilon$NDMs). Our $\upsilon$NDMs represent heart wall geometry and motion through a set of low-dimensional global deformation parameter functions and a diffeomorphic point flow regularized local deformation field. To learn such global and local deformation for 2D apparent motion mapping to 3D true motion, we design a hybrid point transformer, which incorporates both point cross-attention and self-attention mechanisms. While use of point cross-attention can learn to fuse 2D apparent motion cues into material point true motion hints, point self-attention hierarchically organised as an encoder-decoder structure can further learn to refine these hints and map them into 3D true motion. We have performed experiments on a large cohort of synthetic 3D regional heart wall motion dataset. The results demonstrated the high accuracy of our method for the recovery of dense 3D true motion from sparse 2D apparent motion cues. Project page is at https://github.com/DeepTag/VolumetricNeuralDeformableModels.

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Neural Deformable Models for 3D Bi-Ventricular Heart Shape Reconstruction and Modeling from 2D Sparse Cardiac Magnetic Resonance Imaging

We propose a novel neural deformable model (NDM) targeting at the reconstruction and modeling of 3D bi-ventricular shape of the heart from 2D sparse cardiac magnetic resonance (CMR) imaging data. We model the bi-ventricular shape using blended deformable superquadrics, which are parameterized by a set of geometric parameter functions and are capable of deforming globally and locally. While global geometric parameter functions and deformations capture gross shape features from visual data, local deformations, parameterized as neural diffeomorphic point flows, can be learned to recover the detailed heart shape.Different from iterative optimization methods used in conventional deformable model formulations, NDMs can be trained to learn such geometric parameter functions, global and local deformations from a shape distribution manifold. Our NDM can learn to densify a sparse cardiac point cloud with arbitrary scales and generate high-quality triangular meshes automatically. It also enables the implicit learning of dense correspondences among different heart shape instances for accurate cardiac shape registration. Furthermore, the parameters of NDM are intuitive, and can be used by a physician without sophisticated post-processing. Experimental results on a large CMR dataset demonstrate the improved performance of NDM over conventional methods.

cs.CV↗

Continuous Spatio-Temporal Memory Networks for 4D Cardiac Cine MRI Segmentation

Current cardiac cine magnetic resonance image (cMR) studies focus on the end diastole (ED) and end systole (ES) phases, while ignoring the abundant temporal information in the whole image sequence. This is because whole sequence segmentation is currently a tedious process and inaccurate. Conventional whole sequence segmentation approaches first estimate the motion field between frames, which is then used to propagate the mask along the temporal axis. However, the mask propagation results could be prone to error, especially for the basal and apex slices, where through-plane motion leads to significant morphology and structural change during the cardiac cycle. Inspired by recent advances in video object segmentation (VOS), based on spatio-temporal memory (STM) networks, we propose a continuous STM (CSTM) network for semi-supervised whole heart and whole sequence cMR segmentation. Our CSTM network takes full advantage of the spatial, scale, temporal and through-plane continuity prior of the underlying heart anatomy structures, to achieve accurate and fast 4D segmentation. Results of extensive experiments across multiple cMR datasets show that our method can improve the 4D cMR segmentation performance, especially for the hard-to-segment regions.

cs.CV↗

SF-V: Single Forward Video Generation Model

Diffusion-based video generation models have demonstrated remarkable success in obtaining high-fidelity videos through the iterative denoising process. However, these models require multiple denoising steps during sampling, resulting in high computational costs. In this work, we propose a novel approach to obtain single-step video generation models by leveraging adversarial training to fine-tune pre-trained video diffusion models. We show that, through the adversarial training, the multi-steps video diffusion model, i.e., Stable Video Diffusion (SVD), can be trained to perform single forward pass to synthesize high-quality videos, capturing both temporal and spatial dependencies in the video data. Extensive experiments demonstrate that our method achieves competitive generation quality of synthesized videos with significantly reduced computational overhead for the denoising process (i.e., around $23\times$ speedup compared with SVD and $6\times$ speedup compared with existing works, with even better generation quality), paving the way for real-time video synthesis and editing. More visualization results are made publicly available at https://snap-research.github.io/SF-V.

cs.CV↗

Aligning Human Knowledge with Visual Concepts Towards Explainable Medical Image Classification

Although explainability is essential in the clinical diagnosis, most deep learning models still function as black boxes without elucidating their decision-making process. In this study, we investigate the explainable model development that can mimic the decision-making process of human experts by fusing the domain knowledge of explicit diagnostic criteria. We introduce a simple yet effective framework, Explicd, towards Explainable language-informed criteria-based diagnosis. Explicd initiates its process by querying domain knowledge from either large language models (LLMs) or human experts to establish diagnostic criteria across various concept axes (e.g., color, shape, texture, or specific patterns of diseases). By leveraging a pretrained vision-language model, Explicd injects these criteria into the embedding space as knowledge anchors, thereby facilitating the learning of corresponding visual concepts within medical images. The final diagnostic outcome is determined based on the similarity scores between the encoded visual concepts and the textual criteria embeddings. Through extensive evaluation of five medical image classification benchmarks, Explicd has demonstrated its inherent explainability and extends to improve classification performance compared to traditional black-box models. Code is available at \url{https://github.com/yhygao/Explicd}.

cs.CV↗

Resolving Inconsistent Semantics in Multi-Dataset Image Segmentation

Leveraging multiple training datasets to scale up image segmentation models is beneficial for increasing robustness and semantic understanding. Individual datasets have well-defined ground truth with non-overlapping mask layouts and mutually exclusive semantics. However, merging them for multi-dataset training disrupts this harmony and leads to semantic inconsistencies; for example, the class "person" in one dataset and class "face" in another will require multilabel handling for certain pixels. Existing methods struggle with this setting, particularly when evaluated on label spaces mixed from the individual training sets. To overcome these issues, we introduce a simple yet effective multi-dataset training approach by integrating language-based embeddings of class names and label space-specific query embeddings. Our method maintains high performance regardless of the underlying inconsistencies between training datasets. Notably, on four benchmark datasets with label space inconsistencies during inference, we outperform previous methods by 1.6% mIoU for semantic segmentation, 9.1% PQ for panoptic segmentation, 12.1% AP for instance segmentation, and 3.0% in the newly proposed PIQ metric.

cs.CV↗

New Capability to Look Up an ASL Sign from a Video Example

Looking up an unknown sign in an ASL dictionary can be difficult. Most ASL dictionaries are organized based on English glosses, despite the fact that (1) there is no convention for assigning English-based glosses to ASL signs; and (2) there is no 1-1 correspondence between ASL signs and English words. Furthermore, what if the user does not know either the meaning of the target sign or its possible English translation(s)? Some ASL dictionaries enable searching through specification of articulatory properties, such as handshapes, locations, movement properties, etc. However, this is a cumbersome process and does not always result in successful lookup. Here we describe a new system, publicly shared on the Web, to enable lookup of a video of an ASL sign (e.g., a webcam recording or a clip from a continuous signing video). The user submits a video for analysis and is presented with the five most likely sign matches, in decreasing order of likelihood, so that the user can confirm the selection and then be taken to our ASLLRP Sign Bank entry for that sign. Furthermore, this video lookup is also integrated into our newest version of SignStream(R) software to facilitate linguistic annotation of ASL video data, enabling the user to directly look up a sign in the video being annotated, and, upon confirmation of the match, to directly enter into the annotation the gloss and features of that sign, greatly increasing the efficiency and consistency of linguistic annotations of ASL video data.

cs.CV↗

AVID: Any-Length Video Inpainting with Diffusion Model

Recent advances in diffusion models have successfully enabled text-guided image inpainting. While it seems straightforward to extend such editing capability into the video domain, there have been fewer works regarding text-guided video inpainting. Given a video, a masked region at its initial frame, and an editing prompt, it requires a model to do infilling at each frame following the editing guidance while keeping the out-of-mask region intact. There are three main challenges in text-guided video inpainting: ($i$) temporal consistency of the edited video, ($ii$) supporting different inpainting types at different structural fidelity levels, and ($iii$) dealing with variable video length. To address these challenges, we introduce Any-Length Video Inpainting with Diffusion Model, dubbed as AVID. At its core, our model is equipped with effective motion modules and adjustable structure guidance, for fixed-length video inpainting. Building on top of that, we propose a novel Temporal MultiDiffusion sampling pipeline with a middle-frame attention guidance mechanism, facilitating the generation of videos with any desired duration. Our comprehensive experiments show our model can robustly deal with various inpainting types at different video duration ranges, with high quality. More visualization results are made publicly available at https://zhang-zx.github.io/AVID/ .

cs.CV↗

Score-Guided Diffusion for 3D Human Recovery

We present Score-Guided Human Mesh Recovery (ScoreHMR), an approach for solving inverse problems for 3D human pose and shape reconstruction. These inverse problems involve fitting a human body model to image observations, traditionally solved through optimization techniques. ScoreHMR mimics model fitting approaches, but alignment with the image observation is achieved through score guidance in the latent space of a diffusion model. The diffusion model is trained to capture the conditional distribution of the human model parameters given an input image. By guiding its denoising process with a task-specific score, ScoreHMR effectively solves inverse problems for various applications without the need for retraining the task-agnostic diffusion model. We evaluate our approach on three settings/applications. These are: (i) single-frame model fitting; (ii) reconstruction from multiple uncalibrated views; (iii) reconstructing humans in video sequences. ScoreHMR consistently outperforms all optimization baselines on popular benchmarks across all settings. We make our code and models available at the https://statho.github.io/ScoreHMR.

cs.CV↗

On the Challenges and Perspectives of Foundation Models for Medical Image Analysis

This article discusses the opportunities, applications and future directions of large-scale pre-trained models, i.e., foundation models, for analyzing medical images. Medical foundation models have immense potential in solving a wide range of downstream tasks, as they can help to accelerate the development of accurate and robust models, reduce the large amounts of required labeled data, preserve the privacy and confidentiality of patient data. Specifically, we illustrate the "spectrum" of medical foundation models, ranging from general vision models, modality-specific models, to organ/task-specific models, highlighting their challenges, opportunities and applications. We also discuss how foundation models can be leveraged in downstream medical tasks to enhance the accuracy and efficiency of medical image analysis, leading to more precise diagnosis and treatment decisions.

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