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Dingkang Yang

Publications and source records attributed to Dingkang Yang.

At least 91 records · Page 5Linked to original sources

Pathology-knowledge Enhanced Multi-instance Prompt Learning for Few-shot Whole Slide Image Classification

Current multi-instance learning algorithms for pathology image analysis often require a substantial number of Whole Slide Images for effective training but exhibit suboptimal performance in scenarios with limited learning data. In clinical settings, restricted access to pathology slides is inevitable due to patient privacy concerns and the prevalence of rare or emerging diseases. The emergence of the Few-shot Weakly Supervised WSI Classification accommodates the significant challenge of the limited slide data and sparse slide-level labels for diagnosis. Prompt learning based on the pre-trained models (\eg, CLIP) appears to be a promising scheme for this setting; however, current research in this area is limited, and existing algorithms often focus solely on patch-level prompts or confine themselves to language prompts. This paper proposes a multi-instance prompt learning framework enhanced with pathology knowledge, \ie, integrating visual and textual prior knowledge into prompts at both patch and slide levels. The training process employs a combination of static and learnable prompts, effectively guiding the activation of pre-trained models and further facilitating the diagnosis of key pathology patterns. Lightweight Messenger (self-attention) and Summary (attention-pooling) layers are introduced to model relationships between patches and slides within the same patient data. Additionally, alignment-wise contrastive losses ensure the feature-level alignment between visual and textual learnable prompts for both patches and slides. Our method demonstrates superior performance in three challenging clinical tasks, significantly outperforming comparative few-shot methods.

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Can LLMs' Tuning Methods Work in Medical Multimodal Domain?

While Large Language Models (LLMs) excel in world knowledge understanding, adapting them to specific subfields requires precise adjustments. Due to the model's vast scale, traditional global fine-tuning methods for large models can be computationally expensive and impact generalization. To address this challenge, a range of innovative Parameters-Efficient Fine-Tuning (PEFT) methods have emerged and achieved remarkable success in both LLMs and Large Vision-Language Models (LVLMs). In the medical domain, fine-tuning a medical Vision-Language Pretrained (VLP) model is essential for adapting it to specific tasks. Can the fine-tuning methods for large models be transferred to the medical field to enhance transfer learning efficiency? In this paper, we delve into the fine-tuning methods of LLMs and conduct extensive experiments to investigate the impact of fine-tuning methods for large models on the existing multimodal model in the medical domain from the training data level and the model structure level. We show the different impacts of fine-tuning methods for large models on medical VLMs and develop the most efficient ways to fine-tune medical VLP models. We hope this research can guide medical domain researchers in optimizing VLMs' training costs, fostering the broader application of VLMs in healthcare fields. The code and dataset have been released at https://github.com/TIMMY-CHAN/MILE.

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Towards Context-Aware Emotion Recognition Debiasing from a Causal Demystification Perspective via De-confounded Training

Understanding emotions from diverse contexts has received widespread attention in computer vision communities. The core philosophy of Context-Aware Emotion Recognition (CAER) is to provide valuable semantic cues for recognizing the emotions of target persons by leveraging rich contextual information. Current approaches invariably focus on designing sophisticated structures to extract perceptually critical representations from contexts. Nevertheless, a long-neglected dilemma is that a severe context bias in existing datasets results in an unbalanced distribution of emotional states among different contexts, causing biased visual representation learning. From a causal demystification perspective, the harmful bias is identified as a confounder that misleads existing models to learn spurious correlations based on likelihood estimation, limiting the models' performance. To address the issue, we embrace causal inference to disentangle the models from the impact of such bias, and formulate the causalities among variables in the CAER task via a customized causal graph. Subsequently, we present a Contextual Causal Intervention Module (CCIM) to de-confound the confounder, which is built upon backdoor adjustment theory to facilitate seeking approximate causal effects during model training. As a plug-and-play component, CCIM can easily integrate with existing approaches and bring significant improvements. Systematic experiments on three datasets demonstrate the effectiveness of our CCIM.

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Towards Multimodal Sentiment Analysis Debiasing via Bias Purification

Multimodal Sentiment Analysis (MSA) aims to understand human intentions by integrating emotion-related clues from diverse modalities, such as visual, language, and audio. Unfortunately, the current MSA task invariably suffers from unplanned dataset biases, particularly multimodal utterance-level label bias and word-level context bias. These harmful biases potentially mislead models to focus on statistical shortcuts and spurious correlations, causing severe performance bottlenecks. To alleviate these issues, we present a Multimodal Counterfactual Inference Sentiment (MCIS) analysis framework based on causality rather than conventional likelihood. Concretely, we first formulate a causal graph to discover harmful biases from already-trained vanilla models. In the inference phase, given a factual multimodal input, MCIS imagines two counterfactual scenarios to purify and mitigate these biases. Then, MCIS can make unbiased decisions from biased observations by comparing factual and counterfactual outcomes. We conduct extensive experiments on several standard MSA benchmarks. Qualitative and quantitative results show the effectiveness of the proposed framework.

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Self-Cooperation Knowledge Distillation for Novel Class Discovery

Novel Class Discovery (NCD) aims to discover unknown and novel classes in an unlabeled set by leveraging knowledge already learned about known classes. Existing works focus on instance-level or class-level knowledge representation and build a shared representation space to achieve performance improvements. However, a long-neglected issue is the potential imbalanced number of samples from known and novel classes, pushing the model towards dominant classes. Therefore, these methods suffer from a challenging trade-off between reviewing known classes and discovering novel classes. Based on this observation, we propose a Self-Cooperation Knowledge Distillation (SCKD) method to utilize each training sample (whether known or novel, labeled or unlabeled) for both review and discovery. Specifically, the model's feature representations of known and novel classes are used to construct two disjoint representation spaces. Through spatial mutual information, we design a self-cooperation learning to encourage model learning from the two feature representation spaces from itself. Extensive experiments on six datasets demonstrate that our method can achieve significant performance improvements, achieving state-of-the-art performance.

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Skip and Skip: Segmenting Medical Images with Prompts

Most medical image lesion segmentation methods rely on hand-crafted accurate annotations of the original image for supervised learning. Recently, a series of weakly supervised or unsupervised methods have been proposed to reduce the dependence on pixel-level annotations. However, these methods are essentially based on pixel-level annotation, ignoring the image-level diagnostic results of the current massive medical images. In this paper, we propose a dual U-shaped two-stage framework that utilizes image-level labels to prompt the segmentation. In the first stage, we pre-train a classification network with image-level labels, which is used to obtain the hierarchical pyramid features and guide the learning of downstream branches. In the second stage, we feed the hierarchical features obtained from the classification branch into the downstream branch through short-skip and long-skip and get the lesion masks under the supervised learning of pixel-level labels. Experiments show that our framework achieves better results than networks simply using pixel-level annotations.

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MISS: A Generative Pretraining and Finetuning Approach for Med-VQA

Medical visual question answering (VQA) is a challenging multimodal task, where Vision-Language Pre-training (VLP) models can effectively improve the generalization performance. However, most methods in the medical field treat VQA as an answer classification task which is difficult to transfer to practical application scenarios. Additionally, due to the privacy of medical images and the expensive annotation process, large-scale medical image-text pairs datasets for pretraining are severely lacking. In this paper, we propose a large-scale MultI-task Self-Supervised learning based framework (MISS) for medical VQA tasks. Unlike existing methods, we treat medical VQA as a generative task. We unify the text encoder and multimodal encoder and align image-text features through multi-task learning. Furthermore, we propose a Transfer-and-Caption method that extends the feature space of single-modal image datasets using Large Language Models (LLMs), enabling those traditional medical vision field task data to be applied to VLP. Experiments show that our method achieves excellent results with fewer multimodal datasets and demonstrates the advantages of generative VQA models.

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Correlation-Decoupled Knowledge Distillation for Multimodal Sentiment Analysis with Incomplete Modalities

Multimodal sentiment analysis (MSA) aims to understand human sentiment through multimodal data. Most MSA efforts are based on the assumption of modality completeness. However, in real-world applications, some practical factors cause uncertain modality missingness, which drastically degrades the model's performance. To this end, we propose a Correlation-decoupled Knowledge Distillation (CorrKD) framework for the MSA task under uncertain missing modalities. Specifically, we present a sample-level contrastive distillation mechanism that transfers comprehensive knowledge containing cross-sample correlations to reconstruct missing semantics. Moreover, a category-guided prototype distillation mechanism is introduced to capture cross-category correlations using category prototypes to align feature distributions and generate favorable joint representations. Eventually, we design a response-disentangled consistency distillation strategy to optimize the sentiment decision boundaries of the student network through response disentanglement and mutual information maximization. Comprehensive experiments on three datasets indicate that our framework can achieve favorable improvements compared with several baselines.

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Robust Emotion Recognition in Context Debiasing

Context-aware emotion recognition (CAER) has recently boosted the practical applications of affective computing techniques in unconstrained environments. Mainstream CAER methods invariably extract ensemble representations from diverse contexts and subject-centred characteristics to perceive the target person's emotional state. Despite advancements, the biggest challenge remains due to context bias interference. The harmful bias forces the models to rely on spurious correlations between background contexts and emotion labels in likelihood estimation, causing severe performance bottlenecks and confounding valuable context priors. In this paper, we propose a counterfactual emotion inference (CLEF) framework to address the above issue. Specifically, we first formulate a generalized causal graph to decouple the causal relationships among the variables in CAER. Following the causal graph, CLEF introduces a non-invasive context branch to capture the adverse direct effect caused by the context bias. During the inference, we eliminate the direct context effect from the total causal effect by comparing factual and counterfactual outcomes, resulting in bias mitigation and robust prediction. As a model-agnostic framework, CLEF can be readily integrated into existing methods, bringing consistent performance gains.

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Multi-Scale Heterogeneity-Aware Hypergraph Representation for Histopathology Whole Slide Images

Survival prediction is a complex ordinal regression task that aims to predict the survival coefficient ranking among a cohort of patients, typically achieved by analyzing patients' whole slide images. Existing deep learning approaches mainly adopt multiple instance learning or graph neural networks under weak supervision. Most of them are unable to uncover the diverse interactions between different types of biological entities(\textit{e.g.}, cell cluster and tissue block) across multiple scales, while such interactions are crucial for patient survival prediction. In light of this, we propose a novel multi-scale heterogeneity-aware hypergraph representation framework. Specifically, our framework first constructs a multi-scale heterogeneity-aware hypergraph and assigns each node with its biological entity type. It then mines diverse interactions between nodes on the graph structure to obtain a global representation. Experimental results demonstrate that our method outperforms state-of-the-art approaches on three benchmark datasets. Code is publicly available at \href{https://github.com/Hanminghao/H2GT}{https://github.com/Hanminghao/H2GT}.

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Efficiency in Focus: LayerNorm as a Catalyst for Fine-tuning Medical Visual Language Pre-trained Models

In the realm of Medical Visual Language Models (Med-VLMs), the quest for universal efficient fine-tuning mechanisms remains paramount, especially given researchers in interdisciplinary fields are often extremely short of training resources, yet largely unexplored. Given the unique challenges in the medical domain, such as limited data scope and significant domain-specific requirements, evaluating and adapting Parameter-Efficient Fine-Tuning (PEFT) methods specifically for Med-VLMs is essential. Most of the current PEFT methods on Med-VLMs have yet to be comprehensively investigated but mainly focus on adding some components to the model's structure or input. However, fine-tuning intrinsic model components often yields better generality and consistency, and its impact on the ultimate performance of Med-VLMs has been widely overlooked and remains understudied. In this paper, we endeavour to explore an alternative to traditional PEFT methods, especially the impact of fine-tuning LayerNorm layers, FFNs and Attention layers on the Med-VLMs. Our comprehensive studies span both small-scale and large-scale Med-VLMs, evaluating their performance under various fine-tuning paradigms across tasks such as Medical Visual Question Answering and Medical Imaging Report Generation. The findings reveal unique insights into the effects of intrinsic parameter fine-tuning methods on fine-tuning Med-VLMs to downstream tasks and expose fine-tuning solely the LayerNorm layers not only surpasses the efficiency of traditional PEFT methods but also retains the model's accuracy and generalization capabilities across a spectrum of medical downstream tasks. The experiments show LayerNorm fine-tuning's superior adaptability and scalability, particularly in the context of large-scale Med-VLMs.

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De-confounded Data-free Knowledge Distillation for Handling Distribution Shifts

Data-Free Knowledge Distillation (DFKD) is a promising task to train high-performance small models to enhance actual deployment without relying on the original training data. Existing methods commonly avoid relying on private data by utilizing synthetic or sampled data. However, a long-overlooked issue is that the severe distribution shifts between their substitution and original data, which manifests as huge differences in the quality of images and class proportions. The harmful shifts are essentially the confounder that significantly causes performance bottlenecks. To tackle the issue, this paper proposes a novel perspective with causal inference to disentangle the student models from the impact of such shifts. By designing a customized causal graph, we first reveal the causalities among the variables in the DFKD task. Subsequently, we propose a Knowledge Distillation Causal Intervention (KDCI) framework based on the backdoor adjustment to de-confound the confounder. KDCI can be flexibly combined with most existing state-of-the-art baselines. Experiments in combination with six representative DFKD methods demonstrate the effectiveness of our KDCI, which can obviously help existing methods under almost all settings, \textit{e.g.}, improving the baseline by up to 15.54\% accuracy on the CIFAR-100 dataset.

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HandGCAT: Occlusion-Robust 3D Hand Mesh Reconstruction from Monocular Images

We propose a robust and accurate method for reconstructing 3D hand mesh from monocular images. This is a very challenging problem, as hands are often severely occluded by objects. Previous works often have disregarded 2D hand pose information, which contains hand prior knowledge that is strongly correlated with occluded regions. Thus, in this work, we propose a novel 3D hand mesh reconstruction network HandGCAT, that can fully exploit hand prior as compensation information to enhance occluded region features. Specifically, we designed the Knowledge-Guided Graph Convolution (KGC) module and the Cross-Attention Transformer (CAT) module. KGC extracts hand prior information from 2D hand pose by graph convolution. CAT fuses hand prior into occluded regions by considering their high correlation. Extensive experiments on popular datasets with challenging hand-object occlusions, such as HO3D v2, HO3D v3, and DexYCB demonstrate that our HandGCAT reaches state-of-the-art performance. The code is available at https://github.com/heartStrive/HandGCAT.

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Delving into Decision-based Black-box Attacks on Semantic Segmentation

Semantic segmentation is a fundamental visual task that finds extensive deployment in applications with security-sensitive considerations. Nonetheless, recent work illustrates the adversarial vulnerability of semantic segmentation models to white-box attacks. However, its adversarial robustness against black-box attacks has not been fully explored. In this paper, we present the first exploration of black-box decision-based attacks on semantic segmentation. First, we analyze the challenges that semantic segmentation brings to decision-based attacks through the case study. Then, to address these challenges, we first propose a decision-based attack on semantic segmentation, called Discrete Linear Attack (DLA). Based on random search and proxy index, we utilize the discrete linear noises for perturbation exploration and calibration to achieve efficient attack efficiency. We conduct adversarial robustness evaluation on 5 models from Cityscapes and ADE20K under 8 attacks. DLA shows its formidable power on Cityscapes by dramatically reducing PSPNet's mIoU from an impressive 77.83% to a mere 2.14% with just 50 queries.

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Generalized Video Anomaly Event Detection: Systematic Taxonomy and Comparison of Deep Models

Video Anomaly Detection (VAD) serves as a pivotal technology in the intelligent surveillance systems, enabling the temporal or spatial identification of anomalous events within videos. While existing reviews predominantly concentrate on conventional unsupervised methods, they often overlook the emergence of weakly-supervised and fully-unsupervised approaches. To address this gap, this survey extends the conventional scope of VAD beyond unsupervised methods, encompassing a broader spectrum termed Generalized Video Anomaly Event Detection (GVAED). By skillfully incorporating recent advancements rooted in diverse assumptions and learning frameworks, this survey introduces an intuitive taxonomy that seamlessly navigates through unsupervised, weakly-supervised, supervised and fully-unsupervised VAD methodologies, elucidating the distinctions and interconnections within these research trajectories. In addition, this survey facilitates prospective researchers by assembling a compilation of research resources, including public datasets, available codebases, programming tools, and pertinent literature. Furthermore, this survey quantitatively assesses model performance, delves into research challenges and directions, and outlines potential avenues for future exploration.

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Out of Thin Air: Exploring Data-Free Adversarial Robustness Distillation

Adversarial Robustness Distillation (ARD) is a promising task to solve the issue of limited adversarial robustness of small capacity models while optimizing the expensive computational costs of Adversarial Training (AT). Despite the good robust performance, the existing ARD methods are still impractical to deploy in natural high-security scenes due to these methods rely entirely on original or publicly available data with a similar distribution. In fact, these data are almost always private, specific, and distinctive for scenes that require high robustness. To tackle these issues, we propose a challenging but significant task called Data-Free Adversarial Robustness Distillation (DFARD), which aims to train small, easily deployable, robust models without relying on data. We demonstrate that the challenge lies in the lower upper bound of knowledge transfer information, making it crucial to mining and transferring knowledge more efficiently. Inspired by human education, we design a plug-and-play Interactive Temperature Adjustment (ITA) strategy to improve the efficiency of knowledge transfer and propose an Adaptive Generator Balance (AGB) module to retain more data information. Our method uses adaptive hyperparameters to avoid a large number of parameter tuning, which significantly outperforms the combination of existing techniques. Meanwhile, our method achieves stable and reliable performance on multiple benchmarks.

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Spatio-Temporal Domain Awareness for Multi-Agent Collaborative Perception

Multi-agent collaborative perception as a potential application for vehicle-to-everything communication could significantly improve the perception performance of autonomous vehicles over single-agent perception. However, several challenges remain in achieving pragmatic information sharing in this emerging research. In this paper, we propose SCOPE, a novel collaborative perception framework that aggregates the spatio-temporal awareness characteristics across on-road agents in an end-to-end manner. Specifically, SCOPE has three distinct strengths: i) it considers effective semantic cues of the temporal context to enhance current representations of the target agent; ii) it aggregates perceptually critical spatial information from heterogeneous agents and overcomes localization errors via multi-scale feature interactions; iii) it integrates multi-source representations of the target agent based on their complementary contributions by an adaptive fusion paradigm. To thoroughly evaluate SCOPE, we consider both real-world and simulated scenarios of collaborative 3D object detection tasks on three datasets. Extensive experiments demonstrate the superiority of our approach and the necessity of the proposed components.

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CPR-Coach: Recognizing Composite Error Actions based on Single-class Training

The fine-grained medical action analysis task has received considerable attention from pattern recognition communities recently, but it faces the problems of data and algorithm shortage. Cardiopulmonary Resuscitation (CPR) is an essential skill in emergency treatment. Currently, the assessment of CPR skills mainly depends on dummies and trainers, leading to high training costs and low efficiency. For the first time, this paper constructs a vision-based system to complete error action recognition and skill assessment in CPR. Specifically, we define 13 types of single-error actions and 74 types of composite error actions during external cardiac compression and then develop a video dataset named CPR-Coach. By taking the CPR-Coach as a benchmark, this paper thoroughly investigates and compares the performance of existing action recognition models based on different data modalities. To solve the unavoidable Single-class Training & Multi-class Testing problem, we propose a humancognition-inspired framework named ImagineNet to improve the model's multierror recognition performance under restricted supervision. Extensive experiments verify the effectiveness of the framework. We hope this work could advance research toward fine-grained medical action analysis and skill assessment. The CPR-Coach dataset and the code of ImagineNet are publicly available on Github.

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