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Dmitry Beliaev

Publications and source records attributed to Dmitry Beliaev.

28 records · Page 2Linked to original sources

Bifurcations and dynamics emergent from lattice and continuum models of bioactive porous media

We study dynamics emergent from a two-dimensional reaction--diffusion process modelled via a finite lattice dynamical system, as well as an analogous PDE system, involving spatially nonlocal interactions. These models govern the evolution of cells in a bioactive porous medium, with evolution of the local cell density depending on a coupled quasi--static fluid flow problem. We demonstrate differences emergent from the choice of a discrete lattice or a continuum for the spatial domain of such a process. We find long--time oscillations and steady states in cell density in both lattice and continuum models, but that the continuum model only exhibits solutions with vertical symmetry, independent of initial data, whereas the finite lattice admits asymmetric oscillations and steady states arising from symmetry-breaking bifurcations. We conjecture that it is the structure of the finite lattice which allows for more complicated asymmetric dynamics. Our analysis suggests that the origin of both types of oscillations is a nonlocal reaction-diffusion mechanism mediated by quasi-static fluid flow.

q-bio.TO↗

Lattice and Continuum Modelling of a Bioactive Porous Tissue Scaffold

A contemporary procedure to grow artificial tissue is to seed cells onto a porous biomaterial scaffold and culture it within a perfusion bioreactor to facilitate the transport of nutrients to growing cells. Typical models of cell growth for tissue engineering applications make use of spatially homogeneous or spatially continuous equations to model cell growth, flow of culture medium, nutrient transport, and their interactions. The network structure of the physical porous scaffold is often incorporated through parameters in these models, either phenomenologically or through techniques like mathematical homogenization. We derive a model on a square grid lattice to demonstrate the importance of explicitly modelling the network structure of the porous scaffold, and compare results from this model with those from a modified continuum model from the literature. We capture two-way coupling between cell growth and fluid flow by allowing cells to block pores, and by allowing the shear stress of the fluid to affect cell growth and death. We explore a range of parameters for both models, and demonstrate quantitative and qualitative differences between predictions from each of these approaches, including spatial pattern formation and local oscillations in cell density present only in the lattice model. These differences suggest that for some parameter regimes, corresponding to specific cell types and scaffold geometries, the lattice model gives qualitatively different model predictions than typical continuum models. Our results inform model selection for bioactive porous tissue scaffolds, aiding in the development of successful tissue engineering experiments and eventually clinically successful technologies.

q-bio.TO↗

Russo-Seymour-Welsh estimates for the Kostlan ensemble of random polynomials

We study the percolation properties of the nodal structures of random fields. Lower bounds on crossing probabilities (RSW-type estimates) of quads by nodal domains or nodal sets of Gaussian ensembles of smooth random functions are established under the following assumptions: (i) sufficient symmetry; (ii) smoothness and non-degeneracy; (iii) local convergence of the covariance kernels; (iv) asymptotically non-negative correlations; and (v) uniform rapid decay of correlations. The Kostlan ensemble is an important model of Gaussian homogeneous random polynomials. An application of our theory to the Kostlan ensemble yields RSW-type estimates that are uniform with respect to the degree of the polynomials and quads of controlled geometry, valid on all relevant scales. This extends the recent results on the local scaling limit of the Kostlan ensemble, due to Beffara and Gayet.

math.PR↗

How anisotropy beats fractality in two-dimensional on-lattice DLA growth

We study the fractal structure of Diffusion-Limited Aggregation (DLA) clusters on the square lattice by extensive numerical simulations (with clusters having up to $10^8$ particles). We observe that DLA clusters undergo strongly anisotropic growth, with the maximal growth rate along the axes. The naive scaling limit of a DLA cluster by its diameter is thus deterministic and one-dimensional. At the same time, on all scales from the particle size to the size of the entire cluster it has non-trivial box-counting fractal dimension which corresponds to the overall growth rate which, in turn, is smaller than the growth rate along the axes. This suggests that the fractal nature of the lattice DLA should be understood in terms of fluctuations around one-dimensional backbone of the cluster.

cond-mat.stat-mech↗

Integral means spectrum of whole-plane SLE

We complete the mathematical analysis of the fine structure of harmonic measure on SLE curves that was initiated by Beliaev and Smirnov, as described by the averaged integral means spectrum. For the unbounded version of whole-plane SLE as studied by Duplantier, Nguyen, Nguyen and Zinsmeister, and Loutsenko and Yermolayeva, a phase transition has been shown to occur for high enough moments from the bulk spectrum towards a novel spectrum related to the point at infinity. For the bounded version of whole-plane SLE studied here, a similar transition phenomenon, now associated with the SLE origin, is proved to exist for low enough moments, but we show that it is superseded by the earlier occurrence of the transition to the SLE tip spectrum.

math-ph↗

Two point function for critical points of a random plane wave

Random plane wave is conjectured to be a universal model for high-energy eigenfunctions of the Laplace operator on generic compact Riemanian manifolds. This is known to be true on average. In the present paper we discuss one of important geometric observable: critical points. We first compute one-point function for the critical point process, in particular we compute the expected number of critical points inside any open set. After that we compute the short-range asymptotic behaviour of the two-point function. This gives an unexpected result that the second factorial moment of the number of critical points in a small disc scales as the fourth power of the radius.

math-ph↗

Volume distribution of nodal domains of random band-limited functions

We study the volume distribution of nodal domains of random band-limited functions on generic manifolds, and find that in the high energy limit a typical instance obeys a deterministic universal law, independent of the manifold. Some of the basic qualitative properties of this law, such as its support, monotonicity and continuity of the cumulative probability function, are established.

math.PR↗

A Multiscale Guide to Brownian Motion

We revise the Levy's construction of Brownian motion as a simple though still rigorous approach to operate with various Gaussian processes. A Brownian path is explicitly constructed as a linear combination of wavelet-based "geometrical features" at multiple length scales with random weights. Such a wavelet representation gives a closed formula mapping of the unit interval onto the functional space of Brownian paths. This formula elucidates many classical results about Brownian motion (e.g., non-differentiability of its path), providing intuitive feeling for non-mathematicians. The illustrative character of the wavelet representation, along with the simple structure of the underlying probability space, is different from the usual presentation of most classical textbooks. Similar concepts are discussed for fractional Brownian motion, Ornstein-Uhlenbeck process, Gaussian free field, and fractional Gaussian fields. Wavelet representations and dyadic decompositions form the basis of many highly efficient numerical methods to simulate Gaussian processes and fields, including Brownian motion and other diffusive processes in confining domains.

cond-mat.stat-mech↗

Some remarks on SLE bubbles and Schramm's two-point observable

Simmons and Cardy recently predicted a formula for the probability that the chordal SLE(8/3) path passes to the left of two points in the upper half-plane. In this paper we give a rigorous proof of their formula. Starting from this result, we derive explicit expressions for several natural connectivity functions for SLE(8/3) bubbles conditioned to be of macroscopic size. By passing to a limit with such a bubble we construct a certain chordal restriction measure and in this way obtain a proof of a formula for the probability that two given points are between two commuting SLE(8/3) paths. The one-point version of this result has been predicted by Gamsa and Cardy. Finally, we derive an integral formula for the second moment of the area of an SLE(8/3) bubble conditioned to have radius 1. We evaluate the area integral numerically and relate its value to a hypothesis that the area follows the Airy distribution.

math.PR↗