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Dominik Vašinka

Publications and source records attributed to Dominik Vašinka.

5 recordsLinked to original sources

Calibration-free single-frame super-resolution fluorescence microscopy

Molecular fluorescence microscopy is a leading approach to super-resolution and nanoscale imaging in life and material sciences. However, super-resolution fluorescence microscopy is often bottlenecked by system-specific calibrations and long acquisitions of sparsely blinking molecules. We present a deep-learning approach that reconstructs super-resolved images directly from a single diffraction-limited camera frame. The model is trained exclusively on synthetic data encompassing a wide range of optical and sample parameters, enabling robust generalization across microscopes and experimental conditions. Applied to dense terrylene samples with 150 ms acquisition time, our method significantly reduces reconstruction error compared to Richardson-Lucy deconvolution and ThunderSTORM multi-emitter fitting. The results confirm the ability to resolve emitters separated by 35 nm at 580 nm wavelength, corresponding to sevenfold resolution improvement beyond the Rayleigh criterion. Furthermore, we demonstrate strong generalization ability of the developed model and its resilience across a broad range of noise levels, numerical apertures, and optical aberrations. By delivering unprecedented details from a single short camera exposure without prior information and calibration, our approach enables plug-and-play super-resolution imaging of fast, dense, or light-sensitive samples on standard wide-field setups.

physics.optics↗

Universal computational super-resolution framework for imaging of quantum dots

We present a universal deep-learning method that reconstructs super-resolved images of quantum emitters from a single camera frame measurement. Trained on physics-based synthetic data spanning diverse point-spread functions, aberrations, and noise, the network generalizes across experimental conditions without system-specific retraining. We validate the approach on low- and high-density In(Ga)As quantum dots and strain-induced dots in 2D monolayer WSe$_2$, resolving overlapping emitters even under low signal-to-noise and inhomogeneous backgrounds. By eliminating calibration and iterative acquisitions, this single-shot strategy enables rapid, robust computational super-resolution for nanoscale characterization and quantum photonic device fabrication.

quant-ph↗

From Stars to Molecules: AI Guided Device-Agnostic Super-Resolution Imaging

Super-resolution imaging has revolutionized the study of systems ranging from molecular structures to distant galaxies. However, existing super-resolution methods require extensive calibration and retraining for each imaging setup, limiting their practical deployment. We introduce a device-agnostic deep-learning framework for super-resolution imaging of point-like emitters that eliminates the need for calibration data or explicit knowledge of optical system parameters. Our device-agnostic modeling utilizes diverse, numerically simulated dataset encompassing a broad range of imaging conditions, enabling generalization across different optical setups. Once trained, the model reconstructs super-resolved images directly from a single resolution-limited camera frame with superior accuracy and computational efficiency compared to state-of-the-art methods. We experimentally validate our approach using a custom microscopy setup with controllable ground-truth emitter positions. We also demonstrate its versatility on stellar astronomy and single-molecule localization microscopy datasets of point-like sources, achieving high resolution without prior information. Our findings establish a pathway toward universal, calibration-free super-resolution imaging, expanding its applicability across scientific disciplines.

physics.optics↗

All-fiber microendoscopic polarization sensing at single-photon level aided by deep-learning

The polarization of light conveys crucial information about the spatial ordering and optical properties of a specimen. However, precise polarization measurement in challenging conditions, including constrained spaces, low light levels, and high-speed scenarios, remains a severe challenge. Addressing this problem, we introduce a real-time polarization measurement method that is accurate down to a single-photon level and provides complete information about the polarization state. Free of moving components, the polarization sensor utilizes a short rigid piece of few-mode fiber followed by a fiber array and a detector array. The calibration of the sensor relies on a neural network yielding unprecedented accuracy across all polarization states, including partially polarized light. We validate the approach by visualizing the polarization structure of biological specimens and the liquid crystal polymer sample (birefringent USAF test). Our method offers an efficient and reliable solution for real-time polarization sensing and microendoscopy under low-light conditions.

physics.optics↗

Bidirectional deep learning of polarization transfer in liquid crystals with application to quantum state preparation

Accurate control of light polarization represents a core building block in polarization metrology, imaging, and optical and quantum communications. Voltage-controlled liquid crystals offer an efficient way of polarization transformation. However, common twisted nematic liquid crystals are notorious for lacking an accurate theoretical model linking control voltages and output polarization. An inverse model, which would predict control voltages required to prepare a target polarization, is even more challenging. Here we report both the direct and inverse models based on deep neural networks, radial basis functions, and linear interpolation. We present an inverse-direct compound model solving the problem of control voltages ambiguity. We demonstrate one order of magnitude improvement in accuracy using deep learning compared to the radial basis function method and two orders of magnitude improvement compared to the linear interpolation. Errors of the deep neural network model also decrease faster than the other methods with an increasing number of training data. The best direct and inverse models reach the average infidelities of $4 \times 10^{-4}$ and $2 \times 10^{-4}$, respectively, which is the accuracy level not reported yet. Furthermore, we demonstrate local and remote preparation of an arbitrary single-photon polarization state using the deep learning models. The results will impact the application of twisted-nematic liquid crystals, increasing their control accuracy across the board. The presented bidirectional learning can be used for optimal classical control of complex photonic devices and quantum circuits beyond interpolation.

quant-ph↗