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Dong Wei

Publications and source records attributed to Dong Wei.

At least 73 records · Page 4Linked to original sources

Domain Adaptation Meets Zero-Shot Learning: An Annotation-Efficient Approach to Multi-Modality Medical Image Segmentation

Due to the lack of properly annotated medical data, exploring the generalization capability of the deep model is becoming a public concern. Zero-shot learning (ZSL) has emerged in recent years to equip the deep model with the ability to recognize unseen classes. However, existing studies mainly focus on natural images, which utilize linguistic models to extract auxiliary information for ZSL. It is impractical to apply the natural image ZSL solutions directly to medical images, since the medical terminology is very domain-specific, and it is not easy to acquire linguistic models for the medical terminology. In this work, we propose a new paradigm of ZSL specifically for medical images utilizing cross-modality information. We make three main contributions with the proposed paradigm. First, we extract the prior knowledge about the segmentation targets, called relation prototypes, from the prior model and then propose a cross-modality adaptation module to inherit the prototypes to the zero-shot model. Second, we propose a relation prototype awareness module to make the zero-shot model aware of information contained in the prototypes. Last but not least, we develop an inheritance attention module to recalibrate the relation prototypes to enhance the inheritance process. The proposed framework is evaluated on two public cross-modality datasets including a cardiac dataset and an abdominal dataset. Extensive experiments show that the proposed framework significantly outperforms the state of the arts.

cs.CV↗

Deep Convolutional Neural Networks for Molecular Subtyping of Gliomas Using Magnetic Resonance Imaging

Knowledge of molecular subtypes of gliomas can provide valuable information for tailored therapies. This study aimed to investigate the use of deep convolutional neural networks (DCNNs) for noninvasive glioma subtyping with radiological imaging data according to the new taxonomy announced by the World Health Organization in 2016. Methods: A DCNN model was developed for the prediction of the five glioma subtypes based on a hierarchical classification paradigm. This model used three parallel, weight-sharing, deep residual learning networks to process 2.5-dimensional input of trimodal MRI data, including T1-weighted, T1-weighted with contrast enhancement, and T2-weighted images. A data set comprising 1,016 real patients was collected for evaluation of the developed DCNN model. The predictive performance was evaluated via the area under the curve (AUC) from the receiver operating characteristic analysis. For comparison, the performance of a radiomics-based approach was also evaluated. Results: The AUCs of the DCNN model for the four classification tasks in the hierarchical classification paradigm were 0.89, 0.89, 0.85, and 0.66, respectively, as compared to 0.85, 0.75, 0.67, and 0.59 of the radiomics approach. Conclusion: The results showed that the developed DCNN model can predict glioma subtypes with promising performance, given sufficient, non-ill-balanced training data.

eess.IV↗

Conquering Data Variations in Resolution: A Slice-Aware Multi-Branch Decoder Network

Fully convolutional neural networks have made promising progress in joint liver and liver tumor segmentation. Instead of following the debates over 2D versus 3D networks (for example, pursuing the balance between large-scale 2D pretraining and 3D context), in this paper, we novelly identify the wide variation in the ratio between intra- and inter-slice resolutions as a crucial obstacle to the performance. To tackle the mismatch between the intra- and inter-slice information, we propose a slice-aware 2.5D network that emphasizes extracting discriminative features utilizing not only in-plane semantics but also out-of-plane coherence for each separate slice. Specifically, we present a slice-wise multi-input multi-output architecture to instantiate such a design paradigm, which contains a Multi-Branch Decoder (MD) with a Slice-centric Attention Block (SAB) for learning slice-specific features and a Densely Connected Dice (DCD) loss to regularize the inter-slice predictions to be coherent and continuous. Based on the aforementioned innovations, we achieve state-of-the-art results on the MICCAI 2017 Liver Tumor Segmentation (LiTS) dataset. Besides, we also test our model on the ISBI 2019 Segmentation of THoracic Organs at Risk (SegTHOR) dataset, and the result proves the robustness and generalizability of the proposed method in other segmentation tasks.

eess.IV↗

Simultaneous Alignment and Surface Regression Using Hybrid 2D-3D Networks for 3D Coherent Layer Segmentation of Retina OCT Images

Automated surface segmentation of retinal layer is important and challenging in analyzing optical coherence tomography (OCT). Recently, many deep learning based methods have been developed for this task and yield remarkable performance. However, due to large spatial gap and potential mismatch between the B-scans of OCT data, all of them are based on 2D segmentation of individual B-scans, which may loss the continuity information across the B-scans. In addition, 3D surface of the retina layers can provide more diagnostic information, which is crucial in quantitative image analysis. In this study, a novel framework based on hybrid 2D-3D convolutional neural networks (CNNs) is proposed to obtain continuous 3D retinal layer surfaces from OCT. The 2D features of individual B-scans are extracted by an encoder consisting of 2D convolutions. These 2D features are then used to produce the alignment displacement field and layer segmentation by two 3D decoders, which are coupled via a spatial transformer module. The entire framework is trained end-to-end. To the best of our knowledge, this is the first study that attempts 3D retinal layer segmentation in volumetric OCT images based on CNNs. Experiments on a publicly available dataset show that our framework achieves superior results to state-of-the-art 2D methods in terms of both layer segmentation accuracy and cross-B-scan 3D continuity, thus offering more clinical values than previous works.

eess.IV↗

Optimal Attention Management: A Tractable Framework

A well-intentioned principal provides information to a rationally inattentive agent without internalizing the agent's cost of processing information. Whatever information the principal makes available, the agent may choose to ignore some. We study optimal information provision in a tractable model with quadratic payoffs where full disclosure is not optimal. We characterize incentive-compatible information policies, that is, those to which the agent willingly pays full attention. In a leading example with three states, optimal disclosure involves information distortion at intermediate costs of attention. As the cost increases, optimal information abruptly changes from downplaying the state to exaggerating the state.

econ.TH↗

Fast and Incremental Loop Closure Detection with Deep Features and Proximity Graphs

In recent years, the robotics community has extensively examined methods concerning the place recognition task within the scope of simultaneous localization and mapping applications.This article proposes an appearance-based loop closure detection pipeline named ``FILD++" (Fast and Incremental Loop closure Detection).First, the system is fed by consecutive images and, via passing them twice through a single convolutional neural network, global and local deep features are extracted.Subsequently, a hierarchical navigable small-world graph incrementally constructs a visual database representing the robot's traversed path based on the computed global features.Finally, a query image, grabbed each time step, is set to retrieve similar locations on the traversed route.An image-to-image pairing follows, which exploits local features to evaluate the spatial information. Thus, in the proposed article, we propose a single network for global and local feature extraction in contrast to our previous work (FILD), while an exhaustive search for the verification process is adopted over the generated deep local features avoiding the utilization of hash codes. Exhaustive experiments on eleven publicly available datasets exhibit the system's high performance (achieving the highest recall score on eight of them) and low execution times (22.05 ms on average in New College, which is the largest one containing 52480 images) compared to other state-of-the-art approaches.

cs.CV↗

A Unified Framework for Generalized Low-Shot Medical Image Segmentation with Scarce Data

Medical image segmentation has achieved remarkable advancements using deep neural networks (DNNs). However, DNNs often need big amounts of data and annotations for training, both of which can be difficult and costly to obtain. In this work, we propose a unified framework for generalized low-shot (one- and few-shot) medical image segmentation based on distance metric learning (DML). Unlike most existing methods which only deal with the lack of annotations while assuming abundance of data, our framework works with extreme scarcity of both, which is ideal for rare diseases. Via DML, the framework learns a multimodal mixture representation for each category, and performs dense predictions based on cosine distances between the pixels' deep embeddings and the category representations. The multimodal representations effectively utilize the inter-subject similarities and intraclass variations to overcome overfitting due to extremely limited data. In addition, we propose adaptive mixing coefficients for the multimodal mixture distributions to adaptively emphasize the modes better suited to the current input. The representations are implicitly embedded as weights of the fc layer, such that the cosine distances can be computed efficiently via forward propagation. In our experiments on brain MRI and abdominal CT datasets, the proposed framework achieves superior performances for low-shot segmentation towards standard DNN-based (3D U-Net) and classical registration-based (ANTs) methods, e.g., achieving mean Dice coefficients of 81%/69% for brain tissue/abdominal multiorgan segmentation using a single training sample, as compared to 52%/31% and 72%/35% by the U-Net and ANTs, respectively.

cs.CV↗

Fast Monocular Hand Pose Estimation on Embedded Systems

Hand pose estimation is a fundamental task in many human-robot interaction-related applications. However, previous approaches suffer from unsatisfying hand landmark predictions in real-world scenes and high computation burden. This paper proposes a fast and accurate framework for hand pose estimation, dubbed as "FastHand". Using a lightweight encoder-decoder network architecture, FastHand fulfills the requirements of practical applications running on embedded devices. The encoder consists of deep layers with a small number of parameters, while the decoder makes use of spatial location information to obtain more accurate results. The evaluation took place on two publicly available datasets demonstrating the improved performance of the proposed pipeline compared to other state-of-the-art approaches. FastHand offers high accuracy scores while reaching a speed of 25 frames per second on an NVIDIA Jetson TX2 graphics processing unit.

cs.RO↗

Unsupervised Representation Learning Meets Pseudo-Label Supervised Self-Distillation: A New Approach to Rare Disease Classification

Rare diseases are characterized by low prevalence and are often chronically debilitating or life-threatening. Imaging-based classification of rare diseases is challenging due to the severe shortage in training examples. Few-shot learning (FSL) methods tackle this challenge by extracting generalizable prior knowledge from a large base dataset of common diseases and normal controls, and transferring the knowledge to rare diseases. Yet, most existing methods require the base dataset to be labeled and do not make full use of the precious examples of the rare diseases. To this end, we propose in this work a novel hybrid approach to rare disease classification, featuring two key novelties targeted at the above drawbacks. First, we adopt the unsupervised representation learning (URL) based on self-supervising contrastive loss, whereby to eliminate the overhead in labeling the base dataset. Second, we integrate the URL with pseudo-label supervised classification for effective self-distillation of the knowledge about the rare diseases, composing a hybrid approach taking advantages of both unsupervised and (pseudo-) supervised learning on the base dataset. Experimental results on classification of rare skin lesions show that our hybrid approach substantially outperforms existing FSL methods (including those using fully supervised base dataset) for rare disease classification via effective integration of the URL and pseudo-label driven self-distillation, thus establishing a new state of the art.

cs.CV↗

Training Automatic View Planner for Cardiac MR Imaging via Self-Supervision by Spatial Relationship between Views

View planning for the acquisition of cardiac magnetic resonance imaging (CMR) requires acquaintance with the cardiac anatomy and remains a challenging task in clinical practice. Existing approaches to its automation relied either on an additional volumetric image not typically acquired in clinic routine, or on laborious manual annotations of cardiac structural landmarks. This work presents a clinic-compatible and annotation-free system for automatic CMR view planning. The system mines the spatial relationship -- more specifically, locates and exploits the intersecting lines -- between the source and target views, and trains deep networks to regress heatmaps defined by these intersecting lines. As the spatial relationship is self-contained in properly stored data, e.g., in the DICOM format, the need for manual annotation is eliminated. Then, a multi-view planning strategy is proposed to aggregate information from the predicted heatmaps for all the source views of a target view, for a globally optimal prescription. The multi-view aggregation mimics the similar strategy practiced by skilled human prescribers. Experimental results on 181 clinical CMR exams show that our system achieves superior accuracy to existing approaches including conventional atlas-based and newer deep learning based ones, in prescribing four standard CMR views. The mean angle difference and point-to-plane distance evaluated against the ground truth planes are 5.98 degrees and 3.48 mm, respectively.

eess.IV↗

ARShoe: Real-Time Augmented Reality Shoe Try-on System on Smartphones

Virtual try-on technology enables users to try various fashion items using augmented reality and provides a convenient online shopping experience. However, most previous works focus on the virtual try-on for clothes while neglecting that for shoes, which is also a promising task. To this concern, this work proposes a real-time augmented reality virtual shoe try-on system for smartphones, namely ARShoe. Specifically, ARShoe adopts a novel multi-branch network to realize pose estimation and segmentation simultaneously. A solution to generate realistic 3D shoe model occlusion during the try-on process is presented. To achieve a smooth and stable try-on effect, this work further develop a novel stabilization method. Moreover, for training and evaluation, we construct the very first large-scale foot benchmark with multiple virtual shoe try-on task-related labels annotated. Exhaustive experiments on our newly constructed benchmark demonstrate the satisfying performance of ARShoe. Practical tests on common smartphones validate the real-time performance and stabilization of the proposed approach.

cs.CV↗

A New Bidirectional Unsupervised Domain Adaptation Segmentation Framework

Domain shift happens in cross-domain scenarios commonly because of the wide gaps between different domains: when applying a deep learning model well-trained in one domain to another target domain, the model usually performs poorly. To tackle this problem, unsupervised domain adaptation (UDA) techniques are proposed to bridge the gap between different domains, for the purpose of improving model performance without annotation in the target domain. Particularly, UDA has a great value for multimodal medical image analysis, where annotation difficulty is a practical concern. However, most existing UDA methods can only achieve satisfactory improvements in one adaptation direction (e.g., MRI to CT), but often perform poorly in the other (CT to MRI), limiting their practical usage. In this paper, we propose a bidirectional UDA (BiUDA) framework based on disentangled representation learning for equally competent two-way UDA performances. This framework employs a unified domain-aware pattern encoder which not only can adaptively encode images in different domains through a domain controller, but also improve model efficiency by eliminating redundant parameters. Furthermore, to avoid distortion of contents and patterns of input images during the adaptation process, a content-pattern consistency loss is introduced. Additionally, for better UDA segmentation performance, a label consistency strategy is proposed to provide extra supervision by recomposing target-domain-styled images and corresponding source-domain annotations. Comparison experiments and ablation studies conducted on two public datasets demonstrate the superiority of our BiUDA framework to current state-of-the-art UDA methods and the effectiveness of its novel designs. By successfully addressing two-way adaptations, our BiUDA framework offers a flexible solution of UDA techniques to the real-world scenario.

cs.CV↗

Multi-Anchor Active Domain Adaptation for Semantic Segmentation

Unsupervised domain adaption has proven to be an effective approach for alleviating the intensive workload of manual annotation by aligning the synthetic source-domain data and the real-world target-domain samples. Unfortunately, mapping the target-domain distribution to the source-domain unconditionally may distort the essential structural information of the target-domain data. To this end, we firstly propose to introduce a novel multi-anchor based active learning strategy to assist domain adaptation regarding the semantic segmentation task. By innovatively adopting multiple anchors instead of a single centroid, the source domain can be better characterized as a multimodal distribution, thus more representative and complimentary samples are selected from the target domain. With little workload to manually annotate these active samples, the distortion of the target-domain distribution can be effectively alleviated, resulting in a large performance gain. The multi-anchor strategy is additionally employed to model the target-distribution. By regularizing the latent representation of the target samples compact around multiple anchors through a novel soft alignment loss, more precise segmentation can be achieved. Extensive experiments are conducted on public datasets to demonstrate that the proposed approach outperforms state-of-the-art methods significantly, along with thorough ablation study to verify the effectiveness of each component.

cs.CV↗

Learning from Manipulable Signals

We study a dynamic stopping game between a principal and an agent. The agent is privately informed about his type. The principal learns about the agent's type from a noisy performance measure, which can be manipulated by the agent via a costly and hidden action. We fully characterize the unique Markov equilibrium of this game. We find that terminations/market crashes are often preceded by a spike in (expected) performance. Our model also predicts that, due to endogenous signal manipulation, too much transparency can inhibit learning. As the players get arbitrarily patient, the principal elicits no useful information from the observed signal.

econ.TH↗

RECIST-Net: Lesion detection via grouping keypoints on RECIST-based annotation

Universal lesion detection in computed tomography (CT) images is an important yet challenging task due to the large variations in lesion type, size, shape, and appearance. Considering that data in clinical routine (such as the DeepLesion dataset) are usually annotated with a long and a short diameter according to the standard of Response Evaluation Criteria in Solid Tumors (RECIST) diameters, we propose RECIST-Net, a new approach to lesion detection in which the four extreme points and center point of the RECIST diameters are detected. By detecting a lesion as keypoints, we provide a more conceptually straightforward formulation for detection, and overcome several drawbacks (e.g., requiring extensive effort in designing data-appropriate anchors and losing shape information) of existing bounding-box-based methods while exploring a single-task, one-stage approach compared to other RECIST-based approaches. Experiments show that RECIST-Net achieves a sensitivity of 92.49% at four false positives per image, outperforming other recent methods including those using multi-task learning.

cs.CV↗

Generalized Organ Segmentation by Imitating One-shot Reasoning using Anatomical Correlation

Learning by imitation is one of the most significant abilities of human beings and plays a vital role in human's computational neural system. In medical image analysis, given several exemplars (anchors), experienced radiologist has the ability to delineate unfamiliar organs by imitating the reasoning process learned from existing types of organs. Inspired by this observation, we propose OrganNet which learns a generalized organ concept from a set of annotated organ classes and then transfer this concept to unseen classes. In this paper, we show that such process can be integrated into the one-shot segmentation task which is a very challenging but meaningful topic. We propose pyramid reasoning modules (PRMs) to model the anatomical correlation between anchor and target volumes. In practice, the proposed module first computes a correlation matrix between target and anchor computerized tomography (CT) volumes. Then, this matrix is used to transform the feature representations of both anchor volume and its segmentation mask. Finally, OrganNet learns to fuse the representations from various inputs and predicts segmentation results for target volume. Extensive experiments show that OrganNet can effectively resist the wide variations in organ morphology and produce state-of-the-art results in one-shot segmentation task. Moreover, even when compared with fully-supervised segmentation models, OrganNet is still able to produce satisfying segmentation results.

cs.CV↗

Towards efficient quantum memory of orbital angular momentum qubits in cold atoms

The spatial modes of light, carrying a quantized amount of orbital angular momentum (OAM), is one of the excellent candidates that provides access to high-dimensional quantum states, which essentially makes it promising towards building high-dimensional quantum networks. In this paper, we report the storage and retrieval of photonic qubits encoded with OAM state in the cold atomic ensemble, achieving an average conditional fidelity above 98% and retrieval efficiency around 65%. The photonic OAM qubits are encoded with weak coherent states at the single-photon level and the memory is based on electromagnetically induced transparency in an elongated cold rubidium atomic ensemble. Our work constitutes an efficient node that is needed towards high dimensional and large scale quantum networks.

quant-ph↗

Simultaneous recovery of surface heat flux and thickness of a solid structure by ultrasonic measurements

This paper is concerned with a practical inverse problem of simultaneously reconstructing the surface heat flux and the thickness of a solid structure from the associated ultrasonic measurements. In a thermoacoustic coupling model, the thermal boundary condition and the thickness of a solid structure are both unknown, while the measurements of the propagation time by ultrasonic sensors are given. We reformulate the inverse problem as a PDE-constrained optimization problem by constructing a proper objective functional. We then develop an alternating iteration scheme which combines the conjugate gradient method and the deepest decent method to solve the optimization problem. Rigorous convergence analysis is provided for the proposed numerical scheme. By using experimental real data from the lab, we conduct extensive numerical experiments to verify several promising features of the newly developed method.

math.NA↗