Duoyu Feng | Searcharxiv

arXiv2025

Auditory steady-state response and gamma oscillations in an excitatory-inhibitory balanced neuronal network

This study introduces a novel auditory neuronal network model that integrates speech signal input, cochlear processing, and a cortical excitatory-inhibitory (E-I) balanced network. Our findings reveal that increasing noise intensity attenuates the auditory steady-state responses in gamma oscillations, a mechanism validated by public EEG data. Moreover, enhancing the brain's E-I balance significantly improves auditory attention during speech recognition. This work not only elucidates the neural basis of selective attention in noisy environments but also offers a promising therapeutic strategy for auditory attention disorders, marking a significant advancement in the field of computational neuroscience and auditory processing.

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arXiv2024

Closed-loop control of gamma oscillations in the brain connections through the transcranial stimulations

The reconstruction of brain neural network connections occurs not only during the infancy and early childhood stages of brain development, but also in patients with cognitive impairment in middle and old age under the therapy with stimulated external interference, such as the non-invasive repetitive transcranial magnetic stimulation (rTMS) and the transcranial direct current stimulation(tDCS). However, until now, it is not clear how brain stimulation triggers and controls the reconstruction of neural network connections in the brain. This paper combines the EEG data analysis and the cortical neuronal network modeling methods. On one hand, an E-I balanced cortical neural network model was constructed under a long-lasting external stimulation of sinusoidal-exponential form TMS or square-wave tDCS was introduced into the network model for simulate the treatment process for the brain connections. On the other hand, by combining Butterworth filter and functional connectivity algorithm, the paper analyzes the relations between the attentional gamma oscillation responses and the brain connection based on the publicly available EEGs during the pre-tDCS and post-tDCS treatment phases. Firstly, the simulation results indicate that, during long-lasting external stimulations of tDCS/rTMS, The sustained gamma oscillation was found to trigger more release of BDNF from astrocytes to participate in the positively reshaping the excitatory neuronal network connection.

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