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Dylan Franklin

Publications and source records attributed to Dylan Franklin.

2 recordsLinked to original sources

The Role of Lifetime Exposures across Cognitive Domains in Barbados Using Data From the SABE Study

This study characterized the effects of aging on individual cognitive domains and how sex, job type, and years of education alter the age effect on older adults from Barbados. This was an analysis of the cross-sectional data collected as part of the SABE Study (Health, Well-being and Ageing) in 2006. The loss of a single point in each of the individual cognitive domains assessed using the mini-mental state exam served as dependent variables. Independent variables included age, sex, years of education, job type, and the interactions with age in a series of logistic regression analyses. The study aimed to identify which factors altered the effect of age on cognitive performance and which directly affected performance. Results demonstrated that the effect of age differed across the cognitive domains. In addition, sex, education, and job type all differentially affected cognitive performance in an additive, formative manner. The most consistent finding was that high years of education coupled with employment requiring mostly mental effort was the best combination for maintaining high levels of cognitive performance in late life. The results demonstrate that adverse age effects on cognitive performance may be minimized or delayed through modifiable lifetime exposures in the people of Barbados.

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Subjective Difficulty in a Verbal Recognition-based Memory Task: Exploring Brain-behaviour Relationships at the Individual Level in Healthy Young Adults

The vast majority of fMRI studies of task-related brain activity utilize common levels of task demands and analyses that rely on the central tendencies of the data. This approach does not take into account perceived difficulty nor regional variations in brain activity between people. The results are findings of brain-behavior relationships that weaken as sample sizes increase. Participants of the current study included twenty-six healthy young adults evenly split between the sexes. The current work utilizes five parametrically modulated levels of memory load centered around each individual’s predetermined working memory cognitive capacity. Principal components analyses (PCA) identified the group-level central tendency of the data. After removing the group effect from the data, PCA identified individual-level patterns of brain activity across the five levels of task demands. Expression of the group effect significantly differed between the sexes across all load levels. Expression of the individual level patterns demonstrated a significant load by sex interaction. Furthermore, expressions of the individual maps make better predictors of response time behavior than group-derived maps.

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