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Dylan S Small

Publications and source records attributed to Dylan S Small.

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Adaptive discovery of effect modification in matched observational studies

Understanding effect modification -- how treatment effects vary across subpopulations -- is practically important in observational studies, as it helps identify which subgroups are likely to benefit from a given treatment. In this paper, we study the discovery of effect modification in matched observational studies, where each treated unit may be matched to multiple controls. We develop a finite-sample valid procedure for identifying and selecting covariate-interpretable subgroups, with exact control of the subgroup-level false discovery rate (FDR). Our method explicitly accounts for unmeasured confounding via sensitivity models, and leverages multiple matched controls to improve statistical power. We demonstrate the favorable performance of our method relative to baseline methods through extensive simulation studies and a real-world application to the economic returns to college education.

stat.ME

A note on post-treatment selection in studying racial discrimination in policing

We discuss some causal estimands used to study racial discrimination in policing. A central challenge is that not all police-civilian encounters are recorded in administrative datasets and available to researchers. One possible solution is to consider the average causal effect of race conditional on the civilian already being detained by the police. We find that such an estimand can be quite different from the more familiar ones in causal inference and needs to be interpreted with caution. We propose using an estimand new for this context -- the causal risk ratio, which has more transparent interpretation and requires weaker identification assumptions. We demonstrate this through a reanalysis of the NYPD Stop-and-Frisk dataset. Our reanalysis shows that the naive estimator that ignores the post-treatment selection in administrative records may severely underestimate the disparity in police violence between minorities and whites in these and similar data.

stat.AP

Selecting and ranking individualized treatment rules with unmeasured confounding

It is common to compare individualized treatment rules based on the value function, which is the expected potential outcome under the treatment rule. Although the value function is not point-identified when there is unmeasured confounding, it still defines a partial order among the treatment rules under Rosenbaum's sensitivity analysis model. We first consider how to compare two treatment rules with unmeasured confounding in the single-decision setting and then use this pairwise test to rank multiple treatment rules. We consider how to, among many treatment rules, select the best rules and select the rules that are better than a control rule. The proposed methods are illustrated using two real examples, one about the benefit of malaria prevention programs to different age groups and another about the effect of late retirement on senior health in different gender and occupation groups.

stat.ME