Searcharxiv⌕ Search

arXiv subjects

Eduardo Janotti

Publications and source records attributed to Eduardo Janotti.

2 recordsLinked to original sources

Intensity-Based Estimation of Extreme Value Models for Highly Censored Data via a Latent Poisson Process

Extreme value theory provides a natural framework for modelling rare events and extrapolating tail probabilities, but its direct application to survival analysis is complicated by right censoring, heterogeneous follow-up, and the need for coherent inference beyond the range of the observed data. We propose a Bayesian survival model that integrates extreme value theory with a hazard-based formulation built upon the extended generalized Pareto distribution. Rather than separating the bulk and tail of the distribution through an explicit threshold, the proposed model represents the entire hazard function within a unified parametric framework, allowing moderate and extreme survival times to be analysed simultaneously while preserving the asymptotic tail behaviour implied by extreme value theory. Inference is performed through a two-stage procedure. We further develop bias-correction procedures based on latent representative locations and adaptive partition refinement, and establish theoretical results showing the asymptotic consistency of the proposed approximation under standard regularity conditions. Simulation studies demonstrate that the methodology provides reliable uncertainty quantification across a wide range of tail regimes, censoring proportions, and sample sizes, while remaining robust under moderate model misspecification. The practical performance of the approach is illustrated through an analysis of a heart failure cohort, where the proposed model enables inference on long-term survival probabilities and tail behaviour beyond the observed follow-up period. The resulting framework offers a computationally feasible and theoretically grounded alternative for modelling censored survival data when inference on extreme survival times is of primary scientific interest.

stat.ME↗

Long-Term Tail Modeling in Survival Analysis via Extended Generalized Pareto Distributions

We propose a class of extended generalized Pareto models for right-censored survival data, with particular emphasis on tail inference and long-term extrapolation. Our framework integrates extreme value theory and survival analysis, combining a generalized Pareto distribution with a flexible perturbation distribution on the unit interval. We consider three perturbation specifications: a parametric Beta model, a Bernstein polynomial estimator, and a histogram-based estimator. To facilitate direct comparison, all three models are fitted using a unified iterative procedure adapted to right censoring through Kaplan-Meier-based pseudo-observations. A Monte Carlo study evaluates finite-sample performance across different tail indices, censoring levels, sample sizes, and model complexities. The results reveal a trade-off between flexibility and stability: the Beta specification generally performs best for tail-index estimation, whereas the histogram estimator performs particularly well for scale estimation under low censoring. The Bernstein estimator shows intermediate performance and greater sensitivity to sample size and censoring. Applications to bladder cancer recurrence and heart-failure survival data show that models with very similar in-sample fits can nevertheless produce markedly different tail-index estimates and long-term extrapolations. These findings emphasize the importance of perturbation specification when extended generalized Pareto models are used for survival extrapolation under censoring.

stat.ME↗