arXiv subjects

Eitan Yaakobi

Publications and source records attributed to Eitan Yaakobi.

At least 73 records · Page 4Linked to original sources

arXiv2024

Permutation Recovery Problem against Deletion Errors for DNA Data Storage

Owing to its immense storage density and durability, DNA has emerged as a promising storage medium. However, due to technological constraints, data can only be written onto many short DNA molecules called data blocks that are stored in an unordered way. To handle the unordered nature of DNA data storage systems, a unique address is typically prepended to each data block to form a DNA strand. However, DNA storage systems are prone to errors and generate multiple noisy copies of each strand called DNA reads. Thus, we study the permutation recovery problem against deletions errors for DNA data storage. The permutation recovery problem for DNA data storage requires one to reconstruct the addresses or in other words to uniquely identify the noisy reads. By successfully reconstructing the addresses, one can essentially determine the correct order of the data blocks, effectively solving the clustering problem. We first show that we can almost surely identify all the noisy reads under certain mild assumptions. We then propose a permutation recovery procedure and analyze its complexity.

cs.IT↗

arXiv2024

An Optimal Sequence Reconstruction Algorithm for Reed-Solomon Codes

The sequence reconstruction problem, introduced by Levenshtein in 2001, considers a scenario where the sender transmits a codeword from some codebook, and the receiver obtains $N$ noisy outputs of the codeword. We study the problem of efficient reconstruction using $N$ outputs that are each corrupted by at most $t$ substitutions. Specifically, for the ubiquitous Reed-Solomon codes, we adapt the Koetter-Vardy soft-decoding algorithm, presenting a reconstruction algorithm capable of correcting beyond Johnson radius. Furthermore, the algorithm uses $\mathcal{O}(nN)$ field operations, where $n$ is the codeword length.

cs.IT↗

arXiv2024

Deep DNA Storage: Scalable and Robust DNA Storage via Coding Theory and Deep Learning

DNA-based storage is an emerging technology that enables digital information to be archived in DNA molecules. This method enjoys major advantages over magnetic and optical storage solutions such as exceptional information density, enhanced data durability, and negligible power consumption to maintain data integrity. To access the data, an information retrieval process is employed, where some of the main bottlenecks are the scalability and accuracy, which have a natural tradeoff between the two. Here we show a modular and holistic approach that combines Deep Neural Networks (DNN) trained on simulated data, Tensor-Product (TP) based Error-Correcting Codes (ECC), and a safety margin mechanism into a single coherent pipeline. We demonstrated our solution on 3.1MB of information using two different sequencing technologies. Our work improves upon the current leading solutions by up to x3200 increase in speed, 40% improvement in accuracy, and offers a code rate of 1.6 bits per base in a high noise regime. In a broader sense, our work shows a viable path to commercial DNA storage solutions hindered by current information retrieval processes.

cs.IT↗

arXiv2024

Covering All Bases: The Next Inning in DNA Sequencing Efficiency

DNA emerges as a promising medium for the exponential growth of digital data due to its density and durability. This study extends recent research by addressing the \emph{coverage depth problem} in practical scenarios, exploring optimal error-correcting code pairings with DNA storage systems to minimize coverage depth. Conducted within random access settings, the study provides theoretical analyses and experimental simulations to examine the expectation and probability distribution of samples needed for files recovery. Structured into sections covering definitions, analyses, lower bounds, and comparative evaluations of coding schemes, the paper unveils insights into effective coding schemes for optimizing DNA storage systems.

cs.IT↗

arXiv2024

Interactive Byzantine-Resilient Gradient Coding for General Data Assignments

We tackle the problem of Byzantine errors in distributed gradient descent within the Byzantine-resilient gradient coding framework. Our proposed solution can recover the exact full gradient in the presence of $s$ malicious workers with a data replication factor of only $s+1$. It generalizes previous solutions to any data assignment scheme that has a regular replication over all data samples. The scheme detects malicious workers through additional interactive communication and a small number of local computations at the main node, leveraging group-wise comparisons between workers with a provably optimal grouping strategy. The scheme requires at most $s$ interactive rounds that incur a total communication cost logarithmic in the number of data samples.

cs.IT↗

arXiv2024

The Capacity of the Weighted Read Channel

One of the primary sequencing methods gaining prominence in DNA storage is nanopore sequencing, attributed to various factors. In this work, we consider a simplified model of the sequencer, characterized as a channel. This channel takes a sequence and processes it using a sliding window of length $\ell$, shifting the window by $δ$ characters each time. The output of this channel, which we refer to as the read vector, is a vector containing the sums of the entries in each of the windows. The capacity of the channel is defined as the maximal information rate of the channel. Previous works have already revealed capacity values for certain parameters $\ell$ and $δ$. In this work, we show that when $δ< \ell < 2δ$, the capacity value is given by $\frac{1}δ\log_2 \frac{1}{2}(\ell+1+ \sqrt{(\ell+1)^2 - 4(\ell - δ)(\ell-δ+1)})$. Additionally, we construct an upper bound when $2δ< \ell$. Finally, we extend the model to the two-dimensional case and present several results on its capacity.

cs.IT↗

arXiv2024

On the Capacity of DNA Labeling

DNA labeling is a powerful tool in molecular biology and biotechnology that allows for the visualization, detection, and study of DNA at the molecular level. Under this paradigm, a DNA molecule is being labeled by specific k patterns and is then imaged. Then, the resulted image is modeled as a (k + 1)- ary sequence in which any non-zero symbol indicates on the appearance of the corresponding label in the DNA molecule. The primary goal of this work is to study the labeling capacity, which is defined as the maximal information rate that can be obtained using this labeling process. The labeling capacity is computed for any single label and several results are provided for multiple labels as well. Moreover, we provide the optimal minimal number of labels of length one or two that are needed in order to gain labeling capacity of 2.

cs.IT↗

arXiv2024

Byzantine-Resilient Gradient Coding through Local Gradient Computations

We consider gradient coding in the presence of an adversary controlling so-called malicious workers trying to corrupt the computations. Previous works propose the use of MDS codes to treat the responses from malicious workers as errors and correct them using the error-correction properties of the code. This comes at the expense of increasing the replication, i.e., the number of workers each partial gradient is computed by. In this work, we propose a way to reduce the replication to $s+1$ instead of $2s+1$ in the presence of $s$ malicious workers. Our method detects erroneous inputs from the malicious workers, transforming them into erasures. This comes at the expense of $s$ additional local computations at the main node and additional rounds of light communication between the main node and the workers. We define a general framework and give fundamental limits for fractional repetition data allocations. Our scheme is optimal in terms of replication and local computation and incurs a communication cost that is asymptotically, in the size of the dataset, a multiplicative factor away from the derived bound. We furthermore show how additional redundancy can be exploited to reduce the number of local computations and communication cost, or, alternatively, tolerate straggling workers.

cs.IT↗

arXiv2023

Error-Correcting Codes for Nanopore Sequencing

Nanopore sequencing, superior to other sequencing technologies for DNA storage in multiple aspects, has recently attracted considerable attention. Its high error rates, however, demand thorough research on practical and efficient coding schemes to enable accurate recovery of stored data. To this end, we consider a simplified model of a nanopore sequencer inspired by Mao \emph{et al.}, incorporating intersymbol interference and measurement noise. Essentially, our channel model passes a sliding window of length $\ell$ over a $q$-ary input sequence that outputs the \textit{composition} of the enclosed $\ell$ bits and shifts by $δ$ positions with each time step. In this context, the composition of a $q$-ary vector $\bfx$ specifies the number of occurrences in $\bfx$ of each symbol in $\lbrace 0,1,\ldots, q-1\rbrace$. The resulting compositions vector, termed the \emph{read vector}, may also be corrupted by $t$ substitution errors. By employing graph-theoretic techniques, we deduce that for $δ=1$, at least $\log \log n$ symbols of redundancy are required to correct a single ($t=1$) substitution. Finally, for $\ell \geq 3$, we exploit some inherent characteristics of read vectors to arrive at an error-correcting code that is of optimal redundancy up to a (small) additive constant for this setting. This construction is also found to be optimal for the case of reconstruction from two noisy read vectors.

cs.IT↗

arXiv2023

Cover Your Bases: How to Minimize the Sequencing Coverage in DNA Storage Systems

Although the expenses associated with DNA sequencing have been rapidly decreasing, the current cost of sequencing information stands at roughly $120/GB, which is dramatically more expensive than reading from existing archival storage solutions today. In this work, we aim to reduce not only the cost but also the latency of DNA storage by initiating the study of the DNA coverage depth problem, which aims to reduce the required number of reads to retrieve information from the storage system. Under this framework, our main goal is to understand the effect of error-correcting codes and retrieval algorithms on the required sequencing coverage depth. We establish that the expected number of reads that are required for information retrieval is minimized when the channel follows a uniform distribution. We also derive upper and lower bounds on the probability distribution of this number of required reads and provide a comprehensive upper and lower bound on its expected value. We further prove that for a noiseless channel and uniform distribution, MDS codes are optimal in terms of minimizing the expected number of reads. Additionally, we study the DNA coverage depth problem under the random-access setup, in which the user aims to retrieve just a specific information unit from the entire DNA storage system. We prove that the expected retrieval time is at least k for [n,k] MDS codes as well as for other families of codes. Furthermore, we present explicit code constructions that achieve expected retrieval times below k and evaluate their performance through analytical methods and simulations. Lastly, we provide lower bounds on the maximum expected retrieval time. Our findings offer valuable insights for reducing the cost and latency of DNA storage.

cs.DM↗

arXiv2023

M-DAB: An Input-Distribution Optimization Algorithm for Composite DNA Storage by the Multinomial Channel

Recent experiments have shown that the capacity of DNA storage systems may be significantly increased by synthesizing composite DNA letters. In this work, we model a DNA storage channel with composite inputs as a \textit{multinomial channel}, and propose an optimization algorithm for its capacity achieving input distribution, for an arbitrary number of output reads. The algorithm is termed multidimensional dynamic assignment Blahut-Arimoto (M-DAB), and is a generalized version of the DAB algorithm, proposed by Wesel et al. developed for the binomial channel. We also empirically observe a scaling law behavior of the capacity as a function of the support size of the capacity-achieving input distribution.

cs.IT↗

arXiv2023

Storage codes and recoverable systems on lines and grids

A storage code is an assignment of symbols to the vertices of a connected graph $G(V,E)$ with the property that the value of each vertex is a function of the values of its neighbors, or more generally, of a certain neighborhood of the vertex in $G$. In this work we introduce a new construction method of storage codes, enabling one to construct new codes from known ones via an interleaving procedure driven by resolvable designs. We also study storage codes on $\mathbb Z$ and ${\mathbb Z}^2$ (lines and grids), finding closed-form expressions for the capacity of several one and two-dimensional systems depending on their recovery set, using connections between storage codes, graphs, anticodes, and difference-avoiding sets.

cs.IT↗

arXiv2023

Adversarial Torn-paper Codes

We study the adversarial torn-paper channel. This problem is motivated by applications in DNA data storage where the DNA strands that carry information may break into smaller pieces which are received out of order. Our model extends the previously researched probabilistic setting to the worst-case. We develop code constructions for any parameters of the channel for which non-vanishing asymptotic rate is possible and show our constructions achieve asymptotically optimal rate while allowing for efficient encoding and decoding. Finally, we extend our results to related settings included multi-strand storage, presence of substitution errors, or incomplete coverage.

cs.IT↗

arXiv2023

Trading Communication for Computation in Byzantine-Resilient Gradient Coding

We consider gradient coding in the presence of an adversary, controlling so-called malicious workers trying to corrupt the computations. Previous works propose the use of MDS codes to treat the inputs of the malicious workers as errors and correct them using the error-correction properties of the code. This comes at the expense of increasing the replication, i.e., the number of workers each partial gradient is computed by. In this work, we reduce replication by proposing a method that detects the erroneous inputs from the malicious workers, hence transforming them into erasures. For $s$ malicious workers, our solution can reduce the replication to $s+1$ instead of $2s+1$ for each partial gradient at the expense of only $s$ additional computations at the main node and additional rounds of light communication between the main node and the workers. We give fundamental limits of the general framework for fractional repetition data allocation. Our scheme is optimal in terms of replication and local computation but incurs a communication cost that is asymptotically, in the size of the dataset, a multiplicative factor away from the derived bound.

cs.IT↗

arXiv2023

Function-Correcting Codes

In this paper we study function-correcting codes, a new class of codes designed to protect the function evaluation of a message against errors. We show that FCCs are equivalent to irregular-distance codes, i.e., codes that obey some given distance requirement between each pair of codewords. Using these connections, we study irregular-distance codes and derive general upper and lower bounds on their optimal redundancy. Since these bounds heavily depend on the specific function, we provide simplified, suboptimal bounds that are easier to evaluate. We further employ our general results to specific functions of interest and compare our results to standard error-correcting codes, which protect the whole message.

cs.IT↗

arXiv2023

Coding for IBLTs with Listing Guarantees

The Invertible Bloom Lookup Table (IBLT) is a probabilistic data structure for set representation, with applications in network and traffic monitoring. It is known for its ability to list its elements, an operation that succeeds with high probability for sufficiently large table. However, listing can fail even for relatively small sets. This paper extends recent work on the worst-case analysis of IBLT, which guarantees successful listing for all sets of a certain size, by introducing more general IBLT schemes. These schemes allow for greater freedom in the implementation of the insert, delete, and listing operations and demonstrate that the IBLT memory can be reduced while still maintaining successful listing guarantees. The paper also explores the time-memory trade-off of these schemes, some of which are based on linear codes and $B_h$-sequences over finite fields.

cs.IT↗

arXiv2023

Data-Driven Bee Identification for DNA Strands

We study a data-driven approach to the bee identification problem for DNA strands. The bee-identification problem, introduced by Tandon et al. (2019), requires one to identify $M$ bees, each tagged by a unique barcode, via a set of $M$ noisy measurements. Later, Chrisnata et al. (2022) extended the model to case where one observes $N$ noisy measurements of each bee, and applied the model to address the unordered nature of DNA storage systems. In such systems, a unique address is typically prepended to each DNA data block to form a DNA strand, but the address may possibly be corrupted. While clustering is usually used to identify the address of a DNA strand, this requires $\mathcal{M}^2$ data comparisons (when $\mathcal{M}$ is the number of reads). In contrast, the approach of Chrisnata et al. (2022) avoids data comparisons completely. In this work, we study an intermediate, data-driven approach to this identification task. For the binary erasure channel, we first show that we can almost surely correctly identify all DNA strands under certain mild assumptions. Then we propose a data-driven pruning procedure and demonstrate that on average the procedure uses only a fraction of $\mathcal{M}^2$ data comparisons. Specifically, for $\mathcal{M}= 2^n$ and erasure probability $p$, the expected number of data comparisons performed by the procedure is $κ\mathcal{M}^2$, where $\left(\frac{1+2p-p^2}{2}\right)^n \leq κ\leq \left(\frac{1+p}{2}\right)^n $.

cs.IT↗

arXiv2023

Generalized Unique Reconstruction from Substrings

This paper introduces a new family of reconstruction codes which is motivated by applications in DNA data storage and sequencing. In such applications, DNA strands are sequenced by reading some subset of their substrings. While previous works considered two extreme cases in which all substrings of pre-defined lengths are read or substrings are read with no overlap for the single string case, this work studies two extensions of this paradigm. The first extension considers the setup in which consecutive substrings are read with some given minimum overlap. First, an upper bound is provided on the attainable rates of codes that guarantee unique reconstruction. Then, efficient constructions of codes that asymptotically meet that upper bound are presented. In the second extension, we study the setup where multiple strings are reconstructed together. Given the number of strings and their length, we first derive a lower bound on the read substrings' length $\ell$ that is necessary for the existence of multi-strand reconstruction codes with non-vanishing rates. We then present two constructions of such codes and show that their rates approach 1 for values of $\ell$ that asymptotically behave like the lower bound.

cs.IT↗