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Elisa Marini

Publications and source records attributed to Elisa Marini.

6 recordsLinked to original sources

Mathematical analysis and numerical methods for the computation of transport coefficients in molecular dynamics

We review various numerical approaches to compute transport coefficients in molecular dynamics. These approaches can be broadly classified into three groups: (i) nonequilibrium methods based on applying an external driving field to the system, measuring the average response in the system, and evaluating the related linear response coefficient; (ii) approaches reformulating the transport coefficient of interest through a time correlation function for the equilibrium dynamics (the most popular instances being Green--Kubo and Einstein formulas); (iii) transient techniques, where the transport coefficient can be computed by monitoring the return to the steady state of a dynamics perturbed off its stationary distribution. For all three classes of methods, we provide elements of numerical analysis, allowing to estimate or at least quantify the level of numerical errors in the estimator of the transport coefficient; and also briefly present recent attempts to more efficiently compute transport coefficients with variance reduction approaches such as control variates, importance sampling and coupling methods. The computation of transport coefficients remains nonetheless challenging and will continue requiring research efforts in the foreseeable future.

math.NA

Pulse desynchronization of neural populations by targeting the centroid of the limit cycle in phase space

The synchronized activity of neuronal populations can lead to pathological over-synchronization in conditions such as epilepsy and Parkinson disease. Such states can be desynchronized by brief electrical pulses. But when the underlying oscillating system is not known, as in most practical applications, to determine the specific times and intensities of pulses used for desynchronizaton is a difficult inverse problem. Here we propose a desynchronization scheme for neuronal models of bi-variate neural activity, with possible applications in the medical setting. Our main argument is the existence of a peculiar point in the phase space of the system, the centroid, that is both easy to calculate and robust under changes in the coupling constant. This important target point can be used in a control procedure because it lies in the region of minimal return times of the system.

q-bio.NC

Weak conditional propagation of chaos for systems of interacting particles with nearly stable jumps

We consider a system of $N$ interacting particles, described by SDEs driven by Poisson random measures, where the coefficients depend on the empirical measure of the system. Every particle jumps with a jump rate depending on its position. When this happens, all the other particles of the system receive a small random kick which is distributed according to a heavy-tailed random variable belonging to the domain of attraction of an $\alpha$-stable law and scaled by $N^{-1/\alpha},$ where $0<\alpha<2$. We call these jumps collateral jumps. Moreover, in case $0<\alpha<1$, the jumping particle itself undergoes a macroscopic, main jump. Such systems appear in the modeling of large neural networks, such as the human brain. Using a representation of the collateral jump sum as a time-changed random walk, we prove the convergence in law, in Skorokhod space, of this system to a limit infinite-exchangeable system of SDEs driven by a common stable process. This stable process arises due to the stable central limit theorem, and the particles in the limit system are independent and identically distributed, conditionally on that. That is, the $N$-particle system exhibits the conditional propagation of chaos property.

math.PR

Strong propagation of chaos for systems of interacting particles with nearly stable jumps

We consider a system of $N$ interacting particles, described by SDEs driven by Poisson random measures, where the coefficients depend on the empirical measure of the system. Every particle jumps with a jump rate depending on its position. When this happens, all the other particles of the system receive a small random kick which is distributed according to a heavy tailed random variable belonging to the domain of attraction of an $\alpha-$ stable law and scaled by $N^{-1/\alpha},$ where $0 < \alpha <2 .$ We call these jumps collateral jumps. Moreover, in case $ 0 < \alpha < 1, $ the jumping particle itself undergoes a macroscopic, main jump. Such systems appear in the modeling of large neural networks, such as the human brain. The particular scaling of the collateral jumps implies that the limit of the empirical measures of the system is random and equals the conditional distribution of one typical particle in the limit system, given the source of common noise. Thus the system exhibits the conditional propagation of chaos property. The limit system turns out to be solution of a non-linear SDE, driven by an $ \alpha-$stable process. We prove strong unique existence of the limit system and introduce a suitable coupling to obtain the strong convergence of the finite to the limit system, together with precise error bounds for finite time marginals.

math.PR

Noise-induced oscillations for the mean-field Dissipative Contact Process

We study a dissipative version of the contact process, with mean-field interaction, which admits a simple epidemiological interpretation. The propagation of chaos and the corresponding normal fluctuations reveal that the noise present in the finite-size system induces oscillations with a nearly deterministic period and a randomly varying amplitude. This is reminiscent of the emergence of pandemic waves in real epidemics.

math.PR

Noise-induced periodicity in a frustrated network of interacting diffusions

We investigate the emergence of a collective periodic behavior in a frustrated network of interacting diffusions. Particles are divided into two communities depending on their mutual couplings. On the one hand, both intra-population interactions are positive; each particle wants to conform to the average position of the particles in its own community. On the other hand, inter-population interactions have different signs: the particles of one population want to conform to the average position of the particles of the other community, while the particles in the latter want to do the opposite. We show that this system features the phenomenon of noise-induced periodicity: in the infinite volume limit, in a certain range of interaction strengths, although the system has no periodic behavior in the zero-noise limit, a moderate amount of noise may generate an attractive periodic law.

math.PR