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Emad Boctor

Publications and source records attributed to Emad Boctor.

4 recordsLinked to original sources

OpenPros: A Large-Scale Dataset for Limited View Prostate Ultrasound Computed Tomography

Prostate cancer is one of the most prevalent and deadly cancers among men, motivating the development of accurate and accessible imaging technologies for early detection. Ultrasound computed tomography (USCT) reconstructs quantitative tissue parameters such as speed-of-sound (SOS) and is a promising low-cost alternative to existing modalities. However, prostate USCT remains challenging due to limited-angle acquisition, strong tissue heterogeneity, bone-induced wave distortion, and the lack of large-scale, anatomically realistic datasets for method development and evaluation. We introduce OPENPROS, the first large-scale benchmark dataset for limited-angle prostate USCT, designed to systematically evaluate machine learning methods for quantitative inverse problems. OPENPROS contains over 280,000 paired samples of realistic 2D SOS maps and corresponding ultrasound full-waveform data, generated from anatomically accurate 3D digital prostate models derived from 4 clinical MRI/CT scans and 62 ex vivo prostate specimens with experimental ultrasound measurements. Wave propagation is simulated under clinically realistic configurations using open-source finite-difference time-domain and Runge-Kutta solvers. We provide standardized training, in-distribution, and out-of-distribution benchmarks and evaluate representative deep learning baselines. While learning-based methods substantially improve inference speed and reconstruction accuracy over physics-based approaches, results highlight persistent challenges in robustness, generalization, and high-resolution reconstruction quality. By publicly releasing OPENPROS, we establish a rigorous benchmark to support research in inverse problems, physics-guided learning, and operator learning, and to bridge the gap between machine learning research and practical USCT deployment. The dataset is available at https://open-pros.github.io/.

physics.med-ph

Feature-aggregated spatiotemporal spine surface estimation for wearable patch ultrasound volumetric imaging

Clear identification of bone structures is crucial for ultrasound-guided lumbar interventions, but it can be challenging due to the complex shapes of the self-shadowing vertebra anatomy and the extensive background speckle noise from the surrounding soft tissue structures. Therefore, we propose to use a patch-like wearable ultrasound solution to capture the reflective bone surfaces from multiple imaging angles and create 3D bone representations for interventional guidance. In this work, we will present our method for estimating the vertebra bone surfaces by using a spatiotemporal U-Net architecture learning from the B-Mode image and aggregated feature maps of hand-crafted filters. The methods are evaluated on spine phantom image data collected by our proposed miniaturized wearable "patch" ultrasound device, and the results show that a significant improvement on baseline method can be achieved with promising accuracy. Equipped with this surface estimation framework, our wearable ultrasound system can potentially provide intuitive and accurate interventional guidance for clinicians in augmented reality setting.

eess.IV

Insonification Angle-based Ultrasound Volume Reconstruction for Spine Intervention

Ultrasound-guided spine interventions, such as lumbar-puncture procedures, often suffer from the reduced visibility of key anatomical features such as the inter-spinous process space, due to the complex shape of the self-shadowing vertebra. Therefore, we propose to design a wearable 3D ultrasound device capable of imaging the vertebra from multiple insonification angles to improve the 3D bone surface visualization for interventional guidance. In this work, we aim to equip the imaging platform with a reconstruction algorithm taking advantage of the redundant ultrasound beam angles. Specifically, we try to weight each beam's contribution for the same reconstructed voxel during the reconstruction process based on its incidence angle to the estimated bone surface. To validate our approach, we acquired multi-angle ultrasound image data on a spine phantom with a tracked phased array transducer. The results show that with the proposed method the bone surface contrast can be significantly enhanced, providing clearer visual guidance for the clinician to perform spine intervention.

cs.GR

Bi-Directional Semi-Supervised Training of Convolutional Neural Networks for Ultrasound Elastography Displacement Estimation

The performance of ultrasound elastography (USE) heavily depends on the accuracy of displacement estimation. Recently, Convolutional Neural Networks (CNN) have shown promising performance in optical flow estimation and have been adopted for USE displacement estimation. Networks trained on computer vision images are not optimized for USE displacement estimation since there is a large gap between the computer vision images and the high-frequency Radio Frequency (RF) ultrasound data. Many researchers tried to adopt the optical flow CNNs to USE by applying transfer learning to improve the performance of CNNs for USE. However, the ground truth displacement in real ultrasound data is unknown, and simulated data exhibits a domain shift compared to the real data and is also computationally expensive to generate. To resolve this issue, semi-supervised methods have been proposed wherein the networks pre-trained on computer vision images are fine-tuned using real ultrasound data. In this paper, we employ a semi-supervised method by exploiting the first and second-order derivatives of the displacement field for the regularization. We also modify the network structure to estimate both forward and backward displacements, and propose to use consistency between the forward and backward strains as an additional regularizer to further enhance the performance. We validate our method using several experimental phantom and in vivo data. We also show that the network fine-tuned by our proposed method using experimental phantom data performs well on in vivo data similar to the network fine-tuned on in vivo data. Our results also show that the proposed method outperforms current deep learning methods and is comparable to computationally expensive optimization-based algorithms.

eess.IV