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Emmett B. Kendall

Publications and source records attributed to Emmett B. Kendall.

5 recordsLinked to original sources

Conflict Forecasting via Conformal Prediction for Markov Processes

Whether or not a country is at war, or experiencing escalating or deescalating levels of conflict, has massive ramifications on a country's national and foreign policy. Given a country's history of conflict, or lack thereof, future predictions about the war-status of a country are valuable information. In this paper, we present the use of conformal prediction on temporally-dependent data to obtain prediction sets of possible future conflict state-sequences. More specifically, we compare the results of conformal prediction to a likelihood-based prediction strategy when the data are assumed to come from a discrete-state Markov process. A point-prediction may not supply sufficient information because the penalty for a wrong prediction is extreme, and so we consider a machine learning alternative that gives valid uncertainty quantification and is robust to model misspecification. In the data analysis, we present real forecasts of conflict dynamics across multiple countries. Lastly, we comment on the possible limitations of existing approaches for applying conformal prediction to Markovian data, where the exchangeability assumption is violated.

stat.ME↗

Identification of physiological shock in intensive care units via Bayesian regime switching models

Detection of occult hemorrhage (i.e., internal bleeding) in patients in intensive care units (ICUs) can pose significant challenges for critical care workers. Because blood loss may not always be clinically apparent, clinicians rely on monitoring vital signs for specific trends indicative of a hemorrhage event. The inherent difficulties of diagnosing such an event can lead to late intervention by clinicians which has catastrophic consequences. Therefore, a methodology for early detection of hemorrhage has wide utility. We develop a Bayesian regime switching model (RSM) that analyzes trends in patients' vitals and labs to provide a probabilistic assessment of the underlying physiological state that a patient is in at any given time. This article is motivated by a comprehensive dataset we curated from Mayo Clinic of 33,924 real ICU patient encounters. Longitudinal response measurements are modeled as a vector autoregressive process conditional on all latent states up to the current time point, and the latent states follow a Markov process. We present a novel Bayesian sampling routine to learn the posterior probability distribution of the latent physiological states, as well as develop an approach to account for pre-ICU-admission physiological changes. A simulation and real case study illustrate the effectiveness of our approach.

stat.AP↗

Robust inference for geographic regression discontinuity designs: assessing the impact of police precincts

We study variation in policing outcomes attributable to differential policing practices in New York City (NYC) using geographic regression discontinuity designs (GeoRDDs). By focusing on small geographic windows near police precinct boundaries we can estimate local average treatment effects of police precinct practices on arrest rates. We propose estimands and develop estimators for the GeoRDD when the data come from a spatial point process. Standard GeoRDDs rely on continuity assumptions of the potential outcome surface or a local randomization assumption within a window around the boundary. These assumptions, however, can easily be violated in real applications. We develop a novel and robust approach to testing whether there are differences in policing outcomes that are caused by differences in police precinct policies across NYC. Importantly, this approach is applicable to standard regression discontinuity designs with both numeric and point process data. This approach is robust to violations of traditional assumptions made, and is valid under weaker assumptions. We use a unique form of resampling to provide a valid estimate of our test statistic's null distribution even under violations of standard assumptions. This procedure gives substantially different results in the analysis of NYC arrest rates than those that rely on standard assumptions.

stat.ME↗

Beyond time-homogeneity for continuous-time multistate Markov models

Multistate Markov models are a canonical parametric approach for data modeling of observed or latent stochastic processes supported on a finite state space. Continuous-time Markov processes describe data that are observed irregularly over time, as is often the case in longitudinal medical data, for example. Assuming that a continuous-time Markov process is time-homogeneous, a closed-form likelihood function can be derived from the Kolmogorov forward equations -- a system of differential equations with a well-known matrix-exponential solution. Unfortunately, however, the forward equations do not admit an analytical solution for continuous-time, time-inhomogeneous Markov processes, and so researchers and practitioners often make the simplifying assumption that the process is piecewise time-homogeneous. In this paper, we provide intuitions and illustrations of the potential biases for parameter estimation that may ensue in the more realistic scenario that the piecewise-homogeneous assumption is violated, and we advocate for a solution for likelihood computation in a truly time-inhomogeneous fashion. Particular focus is afforded to the context of multistate Markov models that allow for state label misclassifications, which applies more broadly to hidden Markov models (HMMs), and Bayesian computations bypass the necessity for computationally demanding numerical gradient approximations for obtaining maximum likelihood estimates (MLEs). Supplemental materials are available online.

stat.CO↗

Robust Coordinate Ascent Variational Inference with Markov chain Monte Carlo simulations

Variational Inference (VI) is a method that approximates a difficult-to-compute posterior density using better behaved distributional families. VI is an alternative to the already well-studied Markov chain Monte Carlo (MCMC) method of approximating densities. With each algorithm, there are of course benefits and drawbacks; does there exist a combination of the two that mitigates the flaws of both? We propose a method to combine Coordinate Ascent Variational Inference (CAVI) with MCMC. This new methodology, termed Hybrid CAVI, seeks to improve the sensitivity to initialization and convergence problems of CAVI by proposing an initialization using method of moments estimates obtained from a short MCMC burn-in period. Unlike CAVI, Hybrid CAVI proves to also be effective when the posterior is not from a conditionally conjugate exponential family.

stat.CO↗