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Eric P. Xing

Publications and source records attributed to Eric P. Xing.

At least 145 records · Page 8Linked to original sources

DiCE: The Infinitely Differentiable Monte-Carlo Estimator

The score function estimator is widely used for estimating gradients of stochastic objectives in stochastic computation graphs (SCG), eg, in reinforcement learning and meta-learning. While deriving the first-order gradient estimators by differentiating a surrogate loss (SL) objective is computationally and conceptually simple, using the same approach for higher-order derivatives is more challenging. Firstly, analytically deriving and implementing such estimators is laborious and not compliant with automatic differentiation. Secondly, repeatedly applying SL to construct new objectives for each order derivative involves increasingly cumbersome graph manipulations. Lastly, to match the first-order gradient under differentiation, SL treats part of the cost as a fixed sample, which we show leads to missing and wrong terms for estimators of higher-order derivatives. To address all these shortcomings in a unified way, we introduce DiCE, which provides a single objective that can be differentiated repeatedly, generating correct estimators of derivatives of any order in SCGs. Unlike SL, DiCE relies on automatic differentiation for performing the requisite graph manipulations. We verify the correctness of DiCE both through a proof and numerical evaluation of the DiCE derivative estimates. We also use DiCE to propose and evaluate a novel approach for multi-agent learning. Our code is available at https://www.github.com/alshedivat/lola.

cs.LG↗

Toward Controlled Generation of Text

Generic generation and manipulation of text is challenging and has limited success compared to recent deep generative modeling in visual domain. This paper aims at generating plausible natural language sentences, whose attributes are dynamically controlled by learning disentangled latent representations with designated semantics. We propose a new neural generative model which combines variational auto-encoders and holistic attribute discriminators for effective imposition of semantic structures. With differentiable approximation to discrete text samples, explicit constraints on independent attribute controls, and efficient collaborative learning of generator and discriminators, our model learns highly interpretable representations from even only word annotations, and produces realistic sentences with desired attributes. Quantitative evaluation validates the accuracy of sentence and attribute generation.

cs.LG↗

Sample Complexity of Nonparametric Semi-Supervised Learning

We study the sample complexity of semi-supervised learning (SSL) and introduce new assumptions based on the mismatch between a mixture model learned from unlabeled data and the true mixture model induced by the (unknown) class conditional distributions. Under these assumptions, we establish an $Ω(K\log K)$ labeled sample complexity bound without imposing parametric assumptions, where $K$ is the number of classes. Our results suggest that even in nonparametric settings it is possible to learn a near-optimal classifier using only a few labeled samples. Unlike previous theoretical work which focuses on binary classification, we consider general multiclass classification ($K>2$), which requires solving a difficult permutation learning problem. This permutation defines a classifier whose classification error is controlled by the Wasserstein distance between mixing measures, and we provide finite-sample results characterizing the behaviour of the excess risk of this classifier. Finally, we describe three algorithms for computing these estimators based on a connection to bipartite graph matching, and perform experiments to illustrate the superiority of the MLE over the majority vote estimator.

cs.LG↗

Removing Confounding Factors Associated Weights in Deep Neural Networks Improves the Prediction Accuracy for Healthcare Applications

The proliferation of healthcare data has brought the opportunities of applying data-driven approaches, such as machine learning methods, to assist diagnosis. Recently, many deep learning methods have been shown with impressive successes in predicting disease status with raw input data. However, the "black-box" nature of deep learning and the high-reliability requirement of biomedical applications have created new challenges regarding the existence of confounding factors. In this paper, with a brief argument that inappropriate handling of confounding factors will lead to models' sub-optimal performance in real-world applications, we present an efficient method that can remove the influences of confounding factors such as age or gender to improve the across-cohort prediction accuracy of neural networks. One distinct advantage of our method is that it only requires minimal changes of the baseline model's architecture so that it can be plugged into most of the existing neural networks. We conduct experiments across CT-scan, MRA, and EEG brain wave with convolutional neural networks and LSTM to verify the efficiency of our method.

stat.ML↗

Unsupervised Object-Level Video Summarization with Online Motion Auto-Encoder

Unsupervised video summarization plays an important role on digesting, browsing, and searching the ever-growing videos every day, and the underlying fine-grained semantic and motion information (i.e., objects of interest and their key motions) in online videos has been barely touched. In this paper, we investigate a pioneer research direction towards the fine-grained unsupervised object-level video summarization. It can be distinguished from existing pipelines in two aspects: extracting key motions of participated objects, and learning to summarize in an unsupervised and online manner. To achieve this goal, we propose a novel online motion Auto-Encoder (online motion-AE) framework that functions on the super-segmented object motion clips. Comprehensive experiments on a newly-collected surveillance dataset and public datasets have demonstrated the effectiveness of our proposed method.

cs.CV↗

Hybrid Subspace Learning for High-Dimensional Data

The high-dimensional data setting, in which p >> n, is a challenging statistical paradigm that appears in many real-world problems. In this setting, learning a compact, low-dimensional representation of the data can substantially help distinguish signal from noise. One way to achieve this goal is to perform subspace learning to estimate a small set of latent features that capture the majority of the variance in the original data. Most existing subspace learning models, such as PCA, assume that the data can be fully represented by its embedding in one or more latent subspaces. However, in this work, we argue that this assumption is not suitable for many high-dimensional datasets; often only some variables can easily be projected to a low-dimensional space. We propose a hybrid dimensionality reduction technique in which some features are mapped to a low-dimensional subspace while others remain in the original space. Our model leads to more accurate estimation of the latent space and lower reconstruction error. We present a simple optimization procedure for the resulting biconvex problem and show synthetic data results that demonstrate the advantages of our approach over existing methods. Finally, we demonstrate the effectiveness of this method for extracting meaningful features from both gene expression and video background subtraction datasets.

cs.LG↗

Reinforced Auto-Zoom Net: Towards Accurate and Fast Breast Cancer Segmentation in Whole-slide Images

Convolutional neural networks have led to significant breakthroughs in the domain of medical image analysis. However, the task of breast cancer segmentation in whole-slide images (WSIs) is still underexplored. WSIs are large histopathological images with extremely high resolution. Constrained by the hardware and field of view, using high-magnification patches can slow down the inference process and using low-magnification patches can cause the loss of information. In this paper, we aim to achieve two seemingly conflicting goals for breast cancer segmentation: accurate and fast prediction. We propose a simple yet efficient framework Reinforced Auto-Zoom Net (RAZN) to tackle this task. Motivated by the zoom-in operation of a pathologist using a digital microscope, RAZN learns a policy network to decide whether zooming is required in a given region of interest. Because the zoom-in action is selective, RAZN is robust to unbalanced and noisy ground truth labels and can efficiently reduce overfitting. We evaluate our method on a public breast cancer dataset. RAZN outperforms both single-scale and multi-scale baseline approaches, achieving better accuracy at low inference cost.

cs.CV↗

Query-Conditioned Three-Player Adversarial Network for Video Summarization

Video summarization plays an important role in video understanding by selecting key frames/shots. Traditionally, it aims to find the most representative and diverse contents in a video as short summaries. Recently, a more generalized task, query-conditioned video summarization, has been introduced, which takes user queries into consideration to learn more user-oriented summaries. In this paper, we propose a query-conditioned three-player generative adversarial network to tackle this challenge. The generator learns the joint representation of the user query and the video content, and the discriminator takes three pairs of query-conditioned summaries as the input to discriminate the real summary from a generated and a random one. A three-player loss is introduced for joint training of the generator and the discriminator, which forces the generator to learn better summary results, and avoids the generation of random trivial summaries. Experiments on a recently proposed query-conditioned video summarization benchmark dataset show the efficiency and efficacy of our proposed method.

cs.CV↗

Semantic-aware Grad-GAN for Virtual-to-Real Urban Scene Adaption

Recent advances in vision tasks (e.g., segmentation) highly depend on the availability of large-scale real-world image annotations obtained by cumbersome human labors. Moreover, the perception performance often drops significantly for new scenarios, due to the poor generalization capability of models trained on limited and biased annotations. In this work, we resort to transfer knowledge from automatically rendered scene annotations in virtual-world to facilitate real-world visual tasks. Although virtual-world annotations can be ideally diverse and unlimited, the discrepant data distributions between virtual and real-world make it challenging for knowledge transferring. We thus propose a novel Semantic-aware Grad-GAN (SG-GAN) to perform virtual-to-real domain adaption with the ability of retaining vital semantic information. Beyond the simple holistic color/texture transformation achieved by prior works, SG-GAN successfully personalizes the appearance adaption for each semantic region in order to preserve their key characteristic for better recognition. It presents two main contributions to traditional GANs: 1) a soft gradient-sensitive objective for keeping semantic boundaries; 2) a semantic-aware discriminator for validating the fidelity of personalized adaptions with respect to each semantic region. Qualitative and quantitative experiments demonstrate the superiority of our SG-GAN in scene adaption over state-of-the-art GANs. Further evaluations on semantic segmentation on Cityscapes show using adapted virtual images by SG-GAN dramatically improves segmentation performance than original virtual data. We release our code at https://github.com/Peilun-Li/SG-GAN.

cs.CV↗

On Unifying Deep Generative Models

Deep generative models have achieved impressive success in recent years. Generative Adversarial Networks (GANs) and Variational Autoencoders (VAEs), as emerging families for generative model learning, have largely been considered as two distinct paradigms and received extensive independent studies respectively. This paper aims to establish formal connections between GANs and VAEs through a new formulation of them. We interpret sample generation in GANs as performing posterior inference, and show that GANs and VAEs involve minimizing KL divergences of respective posterior and inference distributions with opposite directions, extending the two learning phases of classic wake-sleep algorithm, respectively. The unified view provides a powerful tool to analyze a diverse set of existing model variants, and enables to transfer techniques across research lines in a principled way. For example, we apply the importance weighting method in VAE literatures for improved GAN learning, and enhance VAEs with an adversarial mechanism that leverages generated samples. Experiments show generality and effectiveness of the transferred techniques.

cs.LG↗

Unsupervised Domain Adaptation for Automatic Estimation of Cardiothoracic Ratio

The cardiothoracic ratio (CTR), a clinical metric of heart size in chest X-rays (CXRs), is a key indicator of cardiomegaly. Manual measurement of CTR is time-consuming and can be affected by human subjectivity, making it desirable to design computer-aided systems that assist clinicians in the diagnosis process. Automatic CTR estimation through chest organ segmentation, however, requires large amounts of pixel-level annotated data, which is often unavailable. To alleviate this problem, we propose an unsupervised domain adaptation framework based on adversarial networks. The framework learns domain invariant feature representations from openly available data sources to produce accurate chest organ segmentation for unlabeled datasets. Specifically, we propose a model that enforces our intuition that prediction masks should be domain independent. Hence, we introduce a discriminator that distinguishes segmentation predictions from ground truth masks. We evaluate our system's prediction based on the assessment of radiologists and demonstrate the clinical practicability for the diagnosis of cardiomegaly. We finally illustrate on the JSRT dataset that the semi-supervised performance of our model is also very promising.

cs.CV↗

Techniques for proving Asynchronous Convergence results for Markov Chain Monte Carlo methods

Markov Chain Monte Carlo (MCMC) methods such as Gibbs sampling are finding widespread use in applied statistics and machine learning. These often lead to difficult computational problems, which are increasingly being solved on parallel and distributed systems such as compute clusters. Recent work has proposed running iterative algorithms such as gradient descent and MCMC in parallel asynchronously for increased performance, with good empirical results in certain problems. Unfortunately, for MCMC this parallelization technique requires new convergence theory, as it has been explicitly demonstrated to lead to divergence on some examples. Recent theory on Asynchronous Gibbs sampling describes why these algorithms can fail, and provides a way to alter them to make them converge. In this article, we describe how to apply this theory in a generic setting, to understand the asynchronous behavior of any MCMC algorithm, including those implemented using parameter servers, and those not based on Gibbs sampling.

stat.ML↗

Image-derived generative modeling of pseudo-macromolecular structures - towards the statistical assessment of Electron CryoTomography template matching

Cellular Electron CryoTomography (CECT) is a 3D imaging technique that captures information about the structure and spatial organization of macromolecular complexes within single cells, in near-native state and at sub-molecular resolution. Although template matching is often used to locate macromolecules in a CECT image, it is insufficient as it only measures the relative structural similarity. Therefore, it is preferable to assess the statistical credibility of the decision through hypothesis testing, requiring many templates derived from a diverse population of macromolecular structures. Due to the very limited number of known structures, we need a generative model to efficiently and reliably sample pseudo-structures from the complex distribution of macromolecular structures. To address this challenge, we propose a novel image-derived approach for performing hypothesis testing for template matching by constructing generative models using the generative adversarial network. Finally, we conducted hypothesis testing experiments for template matching on both simulated and experimental subtomograms, allowing us to conclude the identity of subtomograms with high statistical credibility and significantly reducing false positives.

q-bio.QM↗

Orthogonality-Promoting Distance Metric Learning: Convex Relaxation and Theoretical Analysis

Distance metric learning (DML), which learns a distance metric from labeled "similar" and "dissimilar" data pairs, is widely utilized. Recently, several works investigate orthogonality-promoting regularization (OPR), which encourages the projection vectors in DML to be close to being orthogonal, to achieve three effects: (1) high balancedness -- achieving comparable performance on both frequent and infrequent classes; (2) high compactness -- using a small number of projection vectors to achieve a "good" metric; (3) good generalizability -- alleviating overfitting to training data. While showing promising results, these approaches suffer three problems. First, they involve solving non-convex optimization problems where achieving the global optimal is NP-hard. Second, it lacks a theoretical understanding why OPR can lead to balancedness. Third, the current generalization error analysis of OPR is not directly on the regularizer. In this paper, we address these three issues by (1) seeking convex relaxations of the original nonconvex problems so that the global optimal is guaranteed to be achievable; (2) providing a formal analysis on OPR's capability of promoting balancedness; (3) providing a theoretical analysis that directly reveals the relationship between OPR and generalization performance. Experiments on various datasets demonstrate that our convex methods are more effective in promoting balancedness, compactness, and generalization, and are computationally more efficient, compared with the nonconvex methods.

cs.LG↗

Bayesian Nonparametric Kernel-Learning

Kernel methods are ubiquitous tools in machine learning. However, there is often little reason for the common practice of selecting a kernel a priori. Even if a universal approximating kernel is selected, the quality of the finite sample estimator may be greatly affected by the choice of kernel. Furthermore, when directly applying kernel methods, one typically needs to compute a $N \times N$ Gram matrix of pairwise kernel evaluations to work with a dataset of $N$ instances. The computation of this Gram matrix precludes the direct application of kernel methods on large datasets, and makes kernel learning especially difficult. In this paper we introduce Bayesian nonparmetric kernel-learning (BaNK), a generic, data-driven framework for scalable learning of kernels. BaNK places a nonparametric prior on the spectral distribution of random frequencies allowing it to both learn kernels and scale to large datasets. We show that this framework can be used for large scale regression and classification tasks. Furthermore, we show that BaNK outperforms several other scalable approaches for kernel learning on a variety of real world datasets.

stat.ML↗

The Intriguing Properties of Model Explanations

Linear approximations to the decision boundary of a complex model have become one of the most popular tools for interpreting predictions. In this paper, we study such linear explanations produced either post-hoc by a few recent methods or generated along with predictions with contextual explanation networks (CENs). We focus on two questions: (i) whether linear explanations are always consistent or can be misleading, and (ii) when integrated into the prediction process, whether and how explanations affect the performance of the model. Our analysis sheds more light on certain properties of explanations produced by different methods and suggests that learning models that explain and predict jointly is often advantageous.

cs.LG↗

Personalized Survival Prediction with Contextual Explanation Networks

Accurate and transparent prediction of cancer survival times on the level of individual patients can inform and improve patient care and treatment practices. In this paper, we design a model that concurrently learns to accurately predict patient-specific survival distributions and to explain its predictions in terms of patient attributes such as clinical tests or assessments. Our model is flexible and based on a recurrent network, can handle various modalities of data including temporal measurements, and yet constructs and uses simple explanations in the form of patient- and time-specific linear regression. For analysis, we use two publicly available datasets and show that our networks outperform a number of baselines in prediction while providing a way to inspect the reasons behind each prediction.

cs.LG↗

Stability Selection for Structured Variable Selection

In variable or graph selection problems, finding a right-sized model or controlling the number of false positives is notoriously difficult. Recently, a meta-algorithm called Stability Selection was proposed that can provide reliable finite-sample control of the number of false positives. Its benefits were demonstrated when used in conjunction with the lasso and orthogonal matching pursuit algorithms. In this paper, we investigate the applicability of stability selection to structured selection algorithms: the group lasso and the structured input-output lasso. We find that using stability selection often increases the power of both algorithms, but that the presence of complex structure reduces the reliability of error control under stability selection. We give strategies for setting tuning parameters to obtain a good model size under stability selection, and highlight its strengths and weaknesses compared to competing methods screen and clean and cross-validation. We give guidelines about when to use which error control method.

stat.ML↗