arXiv subjects

Erik Meijering

Publications and source records attributed to Erik Meijering.

At least 19 recordsLinked to original sources

arXiv2026

A Hybrid Framework for Song Lyric Annotation Based on Human-LLM Alignment

Emotion recognition of song lyrics is a challenging task since lyrics may not necessarily align with the overall emotion of a song. As a result, lyrics annotation remains largely underexplored. Drawing inspiration from research in large language model (LLM) assisted annotation, we examine the alignment between humans and LLMs for annotation of lyrics by creating a new sentence-level dataset of lyrics. Our observations highlight the subjectivity of the task and the inherent challenges. Following this, we present a hybrid annotation framework that optimizes human and LLM annotation by predicting potential misalignment in annotation.

cs.CL↗

arXiv2026

Paediatric-HGNN: A Hybrid Heterogeneous Graph Neural Network for Detecting Disfluency in Children's Speech via Multiscale Acoustic Fusion

Automated stuttering detection (ASD) systems struggle with paediatric speech due to high acoustic variability in developing voices and the subtle distinction between pathological stuttering and typical developmental disfluencies. We introduce Paediatric-HGNN, a framework using a Context-aware Part-whole Interaction Network (CaPIN) tailored for paediatric data. Instead of conventional 1D signal modelling, our approach builds a heterogeneous graph capturing hierarchical relationships between lexical units (word nodes) and fine-grained acoustic segments (frame nodes). Trained on curated paediatric corpora (UCLASS and FluencyBank), Paediatric-HGNN achieves 82.4% weighted accuracy and a Typical Disfluency F1-score of 0.386. Modelling hierarchical lexical-acoustic interactions captures developmental "searching" behaviour, offering a more robust and interpretable tool for early clinical intervention.

eess.AS↗

arXiv2026

Edge Deep Learning in Computer Vision and Medical Diagnostics: A Comprehensive Survey

Edge deep learning, a paradigm change reconciling edge computing and deep learning, facilitates real-time decision making attuned to environmental factors through the close integration of computational resources and data sources. Here we provide a comprehensive review of the current state of the art in edge deep learning, focusing on computer vision applications, in particular medical diagnostics. An overview of the foundational principles and technical advantages of edge deep learning is presented, emphasising the capacity of this technology to revolutionise a wide range of domains. Furthermore, we present a novel categorisation of edge hardware platforms based on performance and usage scenarios, facilitating platform selection and operational effectiveness. Following this, we dive into approaches to effectively implement deep neural networks on edge devices, encompassing methods such as lightweight design and model compression. Reviewing practical applications in the fields of computer vision in general and medical diagnostics in particular, we demonstrate the profound impact edge-deployed deep learning models can have in real-life situations. Finally, we provide an analysis of potential future directions and obstacles to the adoption of edge deep learning, with the intention to stimulate further investigations and advancements of intelligent edge deep learning solutions. This survey provides researchers and practitioners with a comprehensive reference shedding light on the critical role deep learning plays in the advancement of edge computing applications.

cs.CV↗

arXiv2025

A Survey on Multimodal Music Emotion Recognition

Multimodal music emotion recognition (MMER) is an emerging discipline in music information retrieval that has experienced a surge in interest in recent years. This survey provides a comprehensive overview of the current state-of-the-art in MMER. Discussing the different approaches and techniques used in this field, the paper introduces a four-stage MMER framework, including multimodal data selection, feature extraction, feature processing, and final emotion prediction. The survey further reveals significant advancements in deep learning methods and the increasing importance of feature fusion techniques. Despite these advancements, challenges such as the need for large annotated datasets, datasets with more modalities, and real-time processing capabilities remain. This paper also contributes to the field by identifying critical gaps in current research and suggesting potential directions for future research. The gaps underscore the importance of developing robust, scalable, a interpretable models for MMER, with implications for applications in music recommendation systems, therapeutic tools, and entertainment.

cs.MM↗

arXiv2025

Leveraging Vision-Language Embeddings for Zero-Shot Learning in Histopathology Images

Zero-shot learning holds tremendous potential for histopathology image analysis by enabling models to generalize to unseen classes without extensive labeled data. Recent advancements in vision-language models (VLMs) have expanded the capabilities of ZSL, allowing models to perform tasks without task-specific fine-tuning. However, applying VLMs to histopathology presents considerable challenges due to the complexity of histopathological imagery and the nuanced nature of diagnostic tasks. In this paper, we propose a novel framework called Multi-Resolution Prompt-guided Hybrid Embedding (MR-PHE) to address these challenges in zero-shot histopathology image classification. MR-PHE leverages multiresolution patch extraction to mimic the diagnostic workflow of pathologists, capturing both fine-grained cellular details and broader tissue structures critical for accurate diagnosis. We introduce a hybrid embedding strategy that integrates global image embeddings with weighted patch embeddings, effectively combining local and global contextual information. Additionally, we develop a comprehensive prompt generation and selection framework, enriching class descriptions with domain-specific synonyms and clinically relevant features to enhance semantic understanding. A similarity-based patch weighting mechanism assigns attention-like weights to patches based on their relevance to class embeddings, emphasizing diagnostically important regions during classification. Our approach utilizes pretrained VLM, CONCH for ZSL without requiring domain-specific fine-tuning, offering scalability and reducing dependence on large annotated datasets. Experimental results demonstrate that MR-PHE not only significantly improves zero-shot classification performance on histopathology datasets but also often surpasses fully supervised models.

cs.CV↗

arXiv2025

GRAPHITE: Graph-Based Interpretable Tissue Examination for Enhanced Explainability in Breast Cancer Histopathology

Explainable AI (XAI) in medical histopathology is essential for enhancing the interpretability and clinical trustworthiness of deep learning models in cancer diagnosis. However, the black-box nature of these models often limits their clinical adoption. We introduce GRAPHITE (Graph-based Interpretable Tissue Examination), a post-hoc explainable framework designed for breast cancer tissue microarray (TMA) analysis. GRAPHITE employs a multiscale approach, extracting patches at various magnification levels, constructing an hierarchical graph, and utilising graph attention networks (GAT) with scalewise attention (SAN) to capture scale-dependent features. We trained the model on 140 tumour TMA cores and four benign whole slide images from which 140 benign samples were created, and tested it on 53 pathologist-annotated TMA samples. GRAPHITE outperformed traditional XAI methods, achieving a mean average precision (mAP) of 0.56, an area under the receiver operating characteristic curve (AUROC) of 0.94, and a threshold robustness (ThR) of 0.70, indicating that the model maintains high performance across a wide range of thresholds. In clinical utility, GRAPHITE achieved the highest area under the decision curve (AUDC) of 4.17e+5, indicating reliable decision support across thresholds. These results highlight GRAPHITE's potential as a clinically valuable tool in computational pathology, providing interpretable visualisations that align with the pathologists' diagnostic reasoning and support precision medicine.

eess.IV↗

arXiv2024

Attention-Enhanced Lightweight Hourglass Network for Human Pose Estimation

Pose estimation is a critical task in computer vision with a wide range of applications from activity monitoring to human-robot interaction. However,most of the existing methods are computationally expensive or have complex architecture. Here we propose a lightweight attention based pose estimation network that utilizes depthwise separable convolution and Convolutional Block Attention Module on an hourglass backbone. The network significantly reduces the computational complexity (floating point operations) and the model size (number of parameters) containing only about 10% of parameters of original eight stack Hourglass network. Experiments were conducted on COCO and MPII datasets using a two stack hourglass backbone. The results showed that our model performs well in comparison to six other lightweight pose estimation models with an average precision of 72.07. The model achieves this performance with only 2.3M parameters and 3.7G FLOPs.

cs.CV↗

arXiv2024

TAFM-Net: A Novel Approach to Skin Lesion Segmentation Using Transformer Attention and Focal Modulation

Incorporating modern computer vision techniques into clinical protocols shows promise in improving skin lesion segmentation. The U-Net architecture has been a key model in this area, iteratively improved to address challenges arising from the heterogeneity of dermatologic images due to varying clinical settings, lighting, patient attributes, and hair density. To further improve skin lesion segmentation, we developed TAFM-Net, an innovative model leveraging self-adaptive transformer attention (TA) coupled with focal modulation (FM). Our model integrates an EfficientNetV2B1 encoder, which employs TA to enhance spatial and channel-related saliency, while a densely connected decoder integrates FM within skip connections, enhancing feature emphasis, segmentation performance, and interpretability crucial for medical image analysis. A novel dynamic loss function amalgamates region and boundary information, guiding effective model training. Our model achieves competitive performance, with Jaccard coefficients of 93.64\%, 86.88\% and 92.88\% in the ISIC2016, ISIC2017 and ISIC2018 datasets, respectively, demonstrating its potential in real-world scenarios.

eess.IV↗

arXiv2024

TBConvL-Net: A Hybrid Deep Learning Architecture for Robust Medical Image Segmentation

Deep learning has shown great potential for automated medical image segmentation to improve the precision and speed of disease diagnostics. However, the task presents significant difficulties due to variations in the scale, shape, texture, and contrast of the pathologies. Traditional convolutional neural network (CNN) models have certain limitations when it comes to effectively modelling multiscale context information and facilitating information interaction between skip connections across levels. To overcome these limitations, a novel deep learning architecture is introduced for medical image segmentation, taking advantage of CNNs and vision transformers. Our proposed model, named TBConvL-Net, involves a hybrid network that combines the local features of a CNN encoder-decoder architecture with long-range and temporal dependencies using biconvolutional long-short-term memory (LSTM) networks and vision transformers (ViT). This enables the model to capture contextual channel relationships in the data and account for the uncertainty of segmentation over time. Additionally, we introduce a novel composite loss function that considers both the segmentation robustness and the boundary agreement of the predicted output with the gold standard. Our proposed model shows consistent improvement over the state of the art on ten publicly available datasets of seven different medical imaging modalities.

eess.IV↗

arXiv2024

Deep Joint Denoising and Detection for Enhanced Intracellular Particle Analysis

Reliable analysis of intracellular dynamic processes in time-lapse fluorescence microscopy images requires complete and accurate tracking of all small particles in all time frames of the image sequences. A fundamental first step towards this goal is particle detection. Given the small size of the particles, their detection is greatly affected by image noise. Recent studies have shown that applying image denoising as a preprocessing step indeed improves particle detection and their subsequent tracking. Deep learning based particle detection methods have shown superior results compared to traditional detection methods. However, they do not explicitly aim to remove noise from the images to facilitate detection. Thus we hypothesize that their performance could be further improved. In this paper, we propose a new deep neural network, called DENODET (denoising-detection network), which performs image denoising and particle detection simultaneously. We show that integrative denoising and detection yields more accurate detection results. Our method achieves superior results compared to state-of-the-art particle detection methods on the particle tracking challenge dataset and our own real fluorescence microscopy image data.

eess.IV↗

arXiv2024

Deep multimodal saliency parcellation of cerebellar pathways: linking microstructure and individual function through explainable multitask learning

Parcellation of human cerebellar pathways is essential for advancing our understanding of the human brain. Existing diffusion MRI tractography parcellation methods have been successful in defining major cerebellar fibre tracts, while relying solely on fibre tract structure. However, each fibre tract may relay information related to multiple cognitive and motor functions of the cerebellum. Hence, it may be beneficial for parcellation to consider the potential importance of the fibre tracts for individual motor and cognitive functional performance measures. In this work, we propose a multimodal data-driven method for cerebellar pathway parcellation, which incorporates both measures of microstructure and connectivity, and measures of individual functional performance. Our method involves first training a multitask deep network to predict various cognitive and motor measures from a set of fibre tract structural features. The importance of each structural feature for predicting each functional measure is then computed, resulting in a set of structure-function saliency values that are clustered to parcellate cerebellar pathways. We refer to our method as Deep Multimodal Saliency Parcellation (DeepMSP), as it computes the saliency of structural measures for predicting cognitive and motor functional performance, with these saliencies being applied to the task of parcellation. Applying DeepMSP we found that it was feasible to identify multiple cerebellar pathway parcels with unique structure-function saliency patterns that were stable across training folds.

q-bio.NC↗

arXiv2024

FUTURE-AI: International consensus guideline for trustworthy and deployable artificial intelligence in healthcare

Despite major advances in artificial intelligence (AI) for medicine and healthcare, the deployment and adoption of AI technologies remain limited in real-world clinical practice. In recent years, concerns have been raised about the technical, clinical, ethical and legal risks associated with medical AI. To increase real world adoption, it is essential that medical AI tools are trusted and accepted by patients, clinicians, health organisations and authorities. This work describes the FUTURE-AI guideline as the first international consensus framework for guiding the development and deployment of trustworthy AI tools in healthcare. The FUTURE-AI consortium was founded in 2021 and currently comprises 118 inter-disciplinary experts from 51 countries representing all continents, including AI scientists, clinicians, ethicists, and social scientists. Over a two-year period, the consortium defined guiding principles and best practices for trustworthy AI through an iterative process comprising an in-depth literature review, a modified Delphi survey, and online consensus meetings. The FUTURE-AI framework was established based on 6 guiding principles for trustworthy AI in healthcare, i.e. Fairness, Universality, Traceability, Usability, Robustness and Explainability. Through consensus, a set of 28 best practices were defined, addressing technical, clinical, legal and socio-ethical dimensions. The recommendations cover the entire lifecycle of medical AI, from design, development and validation to regulation, deployment, and monitoring. FUTURE-AI is a risk-informed, assumption-free guideline which provides a structured approach for constructing medical AI tools that will be trusted, deployed and adopted in real-world practice. Researchers are encouraged to take the recommendations into account in proof-of-concept stages to facilitate future translation towards clinical practice of medical AI.

cs.CY↗

arXiv2024

LMBF-Net: A Lightweight Multipath Bidirectional Focal Attention Network for Multifeatures Segmentation

Retinal diseases can cause irreversible vision loss in both eyes if not diagnosed and treated early. Since retinal diseases are so complicated, retinal imaging is likely to show two or more abnormalities. Current deep learning techniques for segmenting retinal images with many labels and attributes have poor detection accuracy and generalisability. This paper presents a multipath convolutional neural network for multifeature segmentation. The proposed network is lightweight and spatially sensitive to information. A patch-based implementation is used to extract local image features, and focal modulation attention blocks are incorporated between the encoder and the decoder for improved segmentation. Filter optimisation is used to prevent filter overlaps and speed up model convergence. A combination of convolution operations and group convolution operations is used to reduce computational costs. This is the first robust and generalisable network capable of segmenting multiple features of fundus images (including retinal vessels, microaneurysms, optic discs, haemorrhages, hard exudates, and soft exudates). The results of our experimental evaluation on more than ten publicly available datasets with multiple features show that the proposed network outperforms recent networks despite having a small number of learnable parameters.

eess.IV↗

arXiv2024

Semi-supervised variational autoencoder for cell feature extraction in multiplexed immunofluorescence images

Advancements in digital imaging technologies have sparked increased interest in using multiplexed immunofluorescence (mIF) images to visualise and identify the interactions between specific immunophenotypes with the tumour microenvironment at the cellular level. Current state-of-the-art multiplexed immunofluorescence image analysis pipelines depend on cell feature representations characterised by morphological and stain intensity-based metrics generated using simple statistical and machine learning-based tools. However, these methods are not capable of generating complex representations of cells. We propose a deep learning-based cell feature extraction model using a variational autoencoder with supervision using a latent subspace to extract cell features in mIF images. We perform cell phenotype classification using a cohort of more than 44,000 multiplexed immunofluorescence cell image patches extracted across 1,093 tissue microarray cores of breast cancer patients, to demonstrate the success of our model against current and alternative methods.

eess.IV↗

arXiv2024

BioFusionNet: Deep Learning-Based Survival Risk Stratification in ER+ Breast Cancer Through Multifeature and Multimodal Data Fusion

Breast cancer is a significant health concern affecting millions of women worldwide. Accurate survival risk stratification plays a crucial role in guiding personalised treatment decisions and improving patient outcomes. Here we present BioFusionNet, a deep learning framework that fuses image-derived features with genetic and clinical data to obtain a holistic profile and achieve survival risk stratification of ER+ breast cancer patients. We employ multiple self-supervised feature extractors (DINO and MoCoV3) pretrained on histopathological patches to capture detailed image features. These features are then fused by a variational autoencoder and fed to a self-attention network generating patient-level features. A co-dual-cross-attention mechanism combines the histopathological features with genetic data, enabling the model to capture the interplay between them. Additionally, clinical data is incorporated using a feed-forward network, further enhancing predictive performance and achieving comprehensive multimodal feature integration. Furthermore, we introduce a weighted Cox loss function, specifically designed to handle imbalanced survival data, which is a common challenge. Our model achieves a mean concordance index of 0.77 and a time-dependent area under the curve of 0.84, outperforming state-of-the-art methods. It predicts risk (high versus low) with prognostic significance for overall survival in univariate analysis (HR=2.99, 95% CI: 1.88--4.78, p<0.005), and maintains independent significance in multivariate analysis incorporating standard clinicopathological variables (HR=2.91, 95\% CI: 1.80--4.68, p<0.005).

cs.CV↗

arXiv2024

Understanding metric-related pitfalls in image analysis validation

Validation metrics are key for the reliable tracking of scientific progress and for bridging the current chasm between artificial intelligence (AI) research and its translation into practice. However, increasing evidence shows that particularly in image analysis, metrics are often chosen inadequately in relation to the underlying research problem. This could be attributed to a lack of accessibility of metric-related knowledge: While taking into account the individual strengths, weaknesses, and limitations of validation metrics is a critical prerequisite to making educated choices, the relevant knowledge is currently scattered and poorly accessible to individual researchers. Based on a multi-stage Delphi process conducted by a multidisciplinary expert consortium as well as extensive community feedback, the present work provides the first reliable and comprehensive common point of access to information on pitfalls related to validation metrics in image analysis. Focusing on biomedical image analysis but with the potential of transfer to other fields, the addressed pitfalls generalize across application domains and are categorized according to a newly created, domain-agnostic taxonomy. To facilitate comprehension, illustrations and specific examples accompany each pitfall. As a structured body of information accessible to researchers of all levels of expertise, this work enhances global comprehension of a key topic in image analysis validation.

cs.CV↗

arXiv2024

Metrics reloaded: Recommendations for image analysis validation

Increasing evidence shows that flaws in machine learning (ML) algorithm validation are an underestimated global problem. Particularly in automatic biomedical image analysis, chosen performance metrics often do not reflect the domain interest, thus failing to adequately measure scientific progress and hindering translation of ML techniques into practice. To overcome this, our large international expert consortium created Metrics Reloaded, a comprehensive framework guiding researchers in the problem-aware selection of metrics. Following the convergence of ML methodology across application domains, Metrics Reloaded fosters the convergence of validation methodology. The framework was developed in a multi-stage Delphi process and is based on the novel concept of a problem fingerprint - a structured representation of the given problem that captures all aspects that are relevant for metric selection, from the domain interest to the properties of the target structure(s), data set and algorithm output. Based on the problem fingerprint, users are guided through the process of choosing and applying appropriate validation metrics while being made aware of potential pitfalls. Metrics Reloaded targets image analysis problems that can be interpreted as a classification task at image, object or pixel level, namely image-level classification, object detection, semantic segmentation, and instance segmentation tasks. To improve the user experience, we implemented the framework in the Metrics Reloaded online tool, which also provides a point of access to explore weaknesses, strengths and specific recommendations for the most common validation metrics. The broad applicability of our framework across domains is demonstrated by an instantiation for various biological and medical image analysis use cases.

cs.CV↗

arXiv2024

MM-SurvNet: Deep Learning-Based Survival Risk Stratification in Breast Cancer Through Multimodal Data Fusion

Survival risk stratification is an important step in clinical decision making for breast cancer management. We propose a novel deep learning approach for this purpose by integrating histopathological imaging, genetic and clinical data. It employs vision transformers, specifically the MaxViT model, for image feature extraction, and self-attention to capture intricate image relationships at the patient level. A dual cross-attention mechanism fuses these features with genetic data, while clinical data is incorporated at the final layer to enhance predictive accuracy. Experiments on the public TCGA-BRCA dataset show that our model, trained using the negative log likelihood loss function, can achieve superior performance with a mean C-index of 0.64, surpassing existing methods. This advancement facilitates tailored treatment strategies, potentially leading to improved patient outcomes.

cs.CV↗