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Erwan Le Pennec

Publications and source records attributed to Erwan Le Pennec.

At least 19 recordsLinked to original sources

Wavelet-Based Multiscale Flow For Realistic Image Deformation in the Large Diffeomorphic Deformation Model Framework

Estimating accurate high-dimensional transformations remains very challenging, especially in a clinical setting. In this paper, we introduce a multiscale parameterization of deformations to enhance registration and atlas estimation in the Large Deformation Diffeomorphic Metric Mapping framework. Using the Haar wavelet transform, a multiscale representation of the initial velocity fields is computed to optimize transformations in a coarse-to-fine fashion. This additional layer of spatial regularization does not modify the underlying model of deformations. As such, it preserves the original kernel Hilbert space structure of the velocity fields, enabling the algorithm to perform efficient gradient descent. Numerical experiments on several datasets, including abnormal fetal brain images, show that compared to the original algorithm, the coarse-to-fine strategy reaches higher performance and yields template images that preserve important details while avoiding unrealistic features. This highly versatile strategy can easily be applied to other mathematical frameworks for almost no additional computational cost.

math.OC↗

Towards Minimax Optimality of Model-based Robust Reinforcement Learning

We study the sample complexity of obtaining an $ε$-optimal policy in \emph{Robust} discounted Markov Decision Processes (RMDPs), given only access to a generative model of the nominal kernel. This problem is widely studied in the non-robust case, and it is known that any planning approach applied to an empirical MDP estimated with $\tilde{\mathcal{O}}(\frac{H^3 \mid S \mid\mid A \mid}{ε^2})$ samples provides an $ε$-optimal policy, which is minimax optimal. Results in the robust case are much more scarce. For $sa$- (resp $s$-)rectangular uncertainty sets, the best known sample complexity is $\tilde{\mathcal{O}}(\frac{H^4 \mid S \mid^2\mid A \mid}{ε^2})$ (resp. $\tilde{\mathcal{O}}(\frac{H^4 \mid S \mid^2\mid A \mid^2}{ε^2})$), for specific algorithms and when the uncertainty set is based on the total variation (TV), the KL or the Chi-square divergences. In this paper, we consider uncertainty sets defined with an $L_p$-ball (recovering the TV case), and study the sample complexity of \emph{any} planning algorithm (with high accuracy guarantee on the solution) applied to an empirical RMDP estimated using the generative model. In the general case, we prove a sample complexity of $\tilde{\mathcal{O}}(\frac{H^4 \mid S \mid\mid A \mid}{ε^2})$ for both the $sa$- and $s$-rectangular cases (improvements of $\mid S \mid$ and $\mid S \mid\mid A \mid$ respectively). When the size of the uncertainty is small enough, we improve the sample complexity to $\tilde{\mathcal{O}}(\frac{H^3 \mid S \mid\mid A \mid }{ε^2})$, recovering the lower-bound for the non-robust case for the first time and a robust lower-bound when the size of the uncertainty is small enough.

cs.LG↗

Bootstrapping Expectiles in Reinforcement Learning

Many classic Reinforcement Learning (RL) algorithms rely on a Bellman operator, which involves an expectation over the next states, leading to the concept of bootstrapping. To introduce a form of pessimism, we propose to replace this expectation with an expectile. In practice, this can be very simply done by replacing the $L_2$ loss with a more general expectile loss for the critic. Introducing pessimism in RL is desirable for various reasons, such as tackling the overestimation problem (for which classic solutions are double Q-learning or the twin-critic approach of TD3) or robust RL (where transitions are adversarial). We study empirically these two cases. For the overestimation problem, we show that the proposed approach, ExpectRL, provides better results than a classic twin-critic. On robust RL benchmarks, involving changes of the environment, we show that our approach is more robust than classic RL algorithms. We also introduce a variation of ExpectRL combined with domain randomization which is competitive with state-of-the-art robust RL agents. Eventually, we also extend \ExpectRL with a mechanism for choosing automatically the expectile value, that is the degree of pessimism

cs.LG↗

Robust Reinforcement Learning with Distributional Risk-averse formulation

Robust Reinforcement Learning tries to make predictions more robust to changes in the dynamics or rewards of the system. This problem is particularly important when the dynamics and rewards of the environment are estimated from the data. In this paper, we approximate the Robust Reinforcement Learning constrained with a $Φ$-divergence using an approximate Risk-Averse formulation. We show that the classical Reinforcement Learning formulation can be robustified using standard deviation penalization of the objective. Two algorithms based on Distributional Reinforcement Learning, one for discrete and one for continuous action spaces are proposed and tested in a classical Gym environment to demonstrate the robustness of the algorithms.

cs.LG↗

Challenging common bolus advisor for self-monitoring type-I diabetes patients using Reinforcement Learning

Patients with diabetes who are self-monitoring have to decide right before each meal how much insulin they should take. A standard bolus advisor exists, but has never actually been proven to be optimal in any sense. We challenged this rule applying Reinforcement Learning techniques on data simulated with T1DM, an FDA-approved simulator developed by Kovatchev et al. modeling the gluco-insulin interaction. Results show that the optimal bolus rule is fairly different from the standard bolus advisor, and if followed can actually avoid hypoglycemia episodes.

stat.ML↗

Learning from both experts and data

In this work we study the problem of inferring a discrete probability distribution using both expert knowledge and empirical data. This is an important issue for many applications where the scarcity of data prevents a purely empirical approach. In this context, it is common to rely first on an initial domain knowledge a priori before proceeding to an online data acquisition. We are particularly interested in the intermediate regime where we do not have enough data to do without the initial expert a priori of the experts, but enough to correct it if necessary. We present here a novel way to tackle this issue with a method providing an objective way to choose the weight to be given to experts compared to data. We show, both empirically and theoretically, that our proposed estimator is always more efficient than the best of the two models (expert or data) within a constant.

cs.LG↗

Automatic detection of Interplanetary Coronal Mass Ejections from in-situ data: a deep learning approach

Decades of studies have suggested several criteria to detect Interplanetary coronal mass ejections (ICME) in time series from in-situ spacecraft measurements. Among them the most common are an enhanced and smoothly rotating magnetic field, a low proton temperature and a low plasma beta. However, these features are not all observed for each ICME due to their strong variability. Visual detection is time-consuming and biased by the observer interpretation leading to non exhaustive, subjective and thus hardly reproducible catalogs. Using convolutional neural networks on sliding windows and peak detection, we provide a fast, automatic and multi-scale detection of ICMEs. The method has been tested on the in-situ data from WIND between 1997 and 2015 and on the 657 ICMEs that were recorded during this period. The method offers an unambiguous visual proxy of ICMEs that gives an interpretation of the data similar to what an expert observer would give. We found at a maximum 197 of the 232 ICMEs of the 2010-2015 period (recall 84 +-4.5 % including 90% of the ICMEs present in the lists of Nieves-Chinchilla et al. (2015) and Chi et al. (2016). The minimal number of False Positives was 25 out of 158 predicted ICMEs (precision 84+-2.6%). Although less accurate, the method also works with one or several missing input parameters. The method has the advantage of improving its performance by just increasing the amount of input data. The generality of the method paves the way for automatic detection of many different event signatures in spacecraft in-situ measurements.

astro-ph.SR↗

A Model-Based Reinforcement Learning Approach for a Rare Disease Diagnostic Task

In this work, we present our various contributions to the objective of building a decision support tool for the diagnosis of rare diseases. Our goal is to achieve a state of knowledge where the uncertainty about the patient's disease is below a predetermined threshold. We aim to reach such states while minimizing the average number of medical tests to perform. In doing so, we take into account the need, in many medical applications, to avoid, as much as possible, any misdiagnosis. To solve this optimization task, we investigate several reinforcement learning algorithm and make them operable in our high-dimensional and sparse-reward setting. We also present a way to combine expert knowledge, expressed as conditional probabilities, with real clinical data. This is crucial because the scarcity of data in the field of rare diseases prevents any approach based solely on clinical data. Finally we show that it is possible to integrate the ontological information about symptoms while remaining in our probabilistic reasoning. It enables our decision support tool to process information given at different level of precision by the user.

cs.LG↗

PAC-Bayesian aggregation of affine estimators

Aggregating estimators using exponential weights depending on their risk appears optimal in expectation but not in probability. We use here a slight overpenalization to obtain oracle inequality in probability for such an explicit aggregation procedure. We focus on the fixed design regression framework and the aggregation of affine estimators and obtain results for a large family of affine estimators under a non necessarily independent sub-Gaussian noise assumptions.

math.ST↗

Adaptive estimation in the nonparametric random coefficients binary choice model by needlet thresholding

In the random coefficients binary choice model, a binary variable equals 1 iff an index $X^\topβ$ is positive.The vectors $X$ and $β$ are independent and belong to the sphere $\mathbb{S}^{d-1}$ in $\mathbb{R}^{d}$.We prove lower bounds on the minimax risk for estimation of the density $f\_β$ over Besov bodies where the loss is a power of the $L^p(\mathbb{S}^{d-1})$ norm for $1\le p\le \infty$. We show that a hard thresholding estimator based on a needlet expansion with data-driven thresholds achieves these lower bounds up to logarithmic factors.

math.ST↗

Clustering and Model Selection via Penalized Likelihood for Different-sized Categorical Data Vectors

In this study, we consider unsupervised clustering of categorical vectors that can be of different size using mixture. We use likelihood maximization to estimate the parameters of the underlying mixture model and a penalization technique to select the number of mixture components. Regardless of the true distribution that generated the data, we show that an explicit penalty, known up to a multiplicative constant, leads to a non-asymptotic oracle inequality with the Kullback-Leibler divergence on the two sides of the inequality. This theoretical result is illustrated by a document clustering application. To this aim a novel robust expectation-maximization algorithm is proposed to estimate the mixture parameters that best represent the different topics. Slope heuristics are used to calibrate the penalty and to select a number of clusters.

math.ST↗

Gaussian Mixture Regression model with logistic weights, a penalized maximum likelihood approach

We wish to estimate conditional density using Gaussian Mixture Regression model with logistic weights and means depending on the covariate. We aim at selecting the number of components of this model as well as the other parameters by a penalized maximum likelihood approach. We provide a lower bound on penalty, proportional up to a logarithmic term to the dimension of each model, that ensures an oracle inequality for our estimator. Our theoretical analysis is supported by some numerical experiments.

math.ST↗

Conditional Density Estimation by Penalized Likelihood Model Selection and Applications

In this technical report, we consider conditional density estimation with a maximum likelihood approach. Under weak assumptions, we obtain a theoretical bound for a Kullback-Leibler type loss for a single model maximum likelihood estimate. We use a penalized model selection technique to select a best model within a collection. We give a general condition on penalty choice that leads to oracle type inequality for the resulting estimate. This construction is applied to two examples of partition-based conditional density models, models in which the conditional density depends only in a piecewise manner from the covariate. The first example relies on classical piecewise polynomial densities while the second uses Gaussian mixtures with varying mixing proportion but same mixture components. We show how this last case is related to an unsupervised segmentation application that has been the source of our motivation to this study.

math.ST↗

Radon needlet thresholding

We provide a new algorithm for the treatment of the noisy inversion of the Radon transform using an appropriate thresholding technique adapted to a well-chosen new localized basis. We establish minimax results and prove their optimality. In particular, we prove that the procedures provided here are able to attain minimax bounds for any $\mathbb {L}_p$ loss. It s important to notice that most of the minimax bounds obtained here are new to our knowledge. It is also important to emphasize the adaptation properties of our procedures with respect to the regularity (sparsity) of the object to recover and to inhomogeneous smoothness. We perform a numerical study that is of importance since we especially have to discuss the cubature problems and propose an averaging procedure that is mostly in the spirit of the cycle spinning performed for periodic signals.

math.ST↗

Bandlet Image Estimation with Model Selection

To estimate geometrically regular images in the white noise model and obtain an adaptive near asymptotic minimaxity result, we consider a model selection based bandlet estimator. This bandlet estimator combines the best basis selection behaviour of the model selection and the approximation properties of the bandlet dictionary. We derive its near asymptotic minimaxity for geometrically regular images as an example of model selection with general dictionary of orthogonal bases. This paper is thus also a self contained tutorial on model selection with orthogonal bases dictionary.

math.ST↗

Inversion of noisy Radon transform by SVD based needlet

A linear method for inverting noisy observations of the Radon transform is developed based on decomposition systems (needlets) with rapidly decaying elements induced by the Radon transform SVD basis. Upper bounds of the risk of the estimator are established in $L^p$ ($1\le p\le \infty$) norms for functions with Besov space smoothness. A practical implementation of the method is given and several examples are discussed.

math.ST↗

Adaptive Dantzig density estimation

This paper deals with the problem of density estimation. We aim at building an estimate of an unknown density as a linear combination of functions of a dictionary. Inspired by Candès and Tao's approach, we propose an $\ell_1$-minimization under an adaptive Dantzig constraint coming from sharp concentration inequalities. This allows to consider a wide class of dictionaries. Under local or global coherence assumptions, oracle inequalities are derived. These theoretical results are also proved to be valid for the natural Lasso estimate associated with our Dantzig procedure. Then, the issue of calibrating these procedures is studied from both theoretical and practical points of view. Finally, a numerical study shows the significant improvement obtained by our procedures when compared with other classical procedures.

math.ST↗

Maxisets for Model Selection

We address the statistical issue of determining the maximal spaces (maxisets) where model selection procedures attain a given rate of convergence. By considering first general dictionaries, then orthonormal bases, we characterize these maxisets in terms of approximation spaces. These results are illustrated by classical choices of wavelet model collections. For each of them, the maxisets are described in terms of functional spaces. We take a special care of the issue of calculability and measure the induced loss of performance in terms of maxisets.

math.ST↗