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Estelle Pitard

Publications and source records attributed to Estelle Pitard.

17 recordsLinked to original sources

Role of cilia activity and surrounding viscous fluid on properties of metachronal waves

Large groups of active cilia collectively beat in a fluid medium as metachronal waves, essential for some microorganisms motility and for flow generation in mucociliary clearance. Several models can predict the emergence of metachronal waves, but what controls the properties of metachronal waves is still unclear. Here, we investigate numerically a simple model for cilia in the presence of noise on regular lattices in one- and two-dimensions. We characterize the wave using spatial correlation and the frequency of collective beating. Our results clearly show that the viscosity of the fluid medium does not affect the wavelength; the activity of the cilia does. These numerical results are supported by a dimensional analysis, which is expected to be robust against the model for active force generation, unless surrounding fluid influences the cilia activity. Interestingly, enhancement of cilia activity increases the wavelength and decreases the beating frequency, keeping the wave velocity almost unchanged. These results might have significance in understanding paramecium locomotion and mucociliary clearance diseases.

cond-mat.soft

TASEP Exit Times

We address the question of the time needed by $N$ particles, initially located on the first sites of a finite 1D lattice of size $L$, to exit that lattice when they move according to a TASEP transport model. Using analytical calculations and numerical simulations, we show that when $N \ll L$, the mean exit time of the particles is asymptotically given by $T_N(L) \sim L+β_N \sqrt{L}$ for large lattices. Building upon exact results obtained for 2 particles, we devise an approximate continuous space and time description of the random motion of the particles that provides an analytical recursive relation for the coefficients $β_N$. The results are shown to be in very good agreement with numerical results. This approach sheds some light on the exit dynamics of $N$ particles in the regime where $N$ is finite while the lattice size $L\rightarrow \infty$. This complements previous asymptotic results obtained by Johansson in \cite{Johansson2000} in the limit where both $N$ and $L$ tend to infinity while keeping the particle density $N/L$ finite.

cond-mat.dis-nn

Role of spatial heterogeneity on the collective dynamics of cilia beating in a minimal 1D model

Cilia are elastic hairlike protuberances of the cell membrane found in various unicellular organisms and in several tissues of most living organisms. In some tissues such as the airway tissues of the lung, the coordinated beating of cilia induce a fluid flow of crucial importance as it allows the continuous cleaning of our bronchia, known as mucociliary clearance. While most of the models addressing the question of collective dynamics and metachronal wave consider homogeneous carpets of cilia, experimental observations rather show that cilia clusters are heterogeneously distributed over the tissue surface. The purpose of this paper is to investigate the role of spatial heterogeneity on the coherent beating of cilia using a very simple one dimensional model for cilia known as the rower model. We systematically study systems consisting of a few rowers to hundreds of rowers and we investigate the conditions for the emergence of collective beating. When considering a small number of rowers, a phase drift occurs, hence a bifurcation in beating frequency is observed as the distance between rowers clusters is changed. In the case of many rowers, a distribution of frequencies is observed. We found in particular the pattern of the patchy structure that shows the best robustness in collective beating behavior, as the density of cilia is varied over a wide range.

cond-mat.soft

Activity statistics in a colloidal glass former: experimental evidence for a dynamical transition

In a dense colloidal suspension at a volume fraction slightly lower than that of its glass transition, we follow the trajectories of an assembly of tracers over a large time window. We define a local activity, which quantifies the local tendency of the system to rearrange. We determine the statistics of the time and space integrated activity, and we argue that it develops a low activity tail that comes on a par with the onset of glassy behavior and heterogeneous dynamics. These rare events may be interpreted as the reflection of an underlying dynamic phase transition.

cond-mat.soft

Transport on a Lattice with Dynamical Defects

Many transport processes in nature take place on substrates, often considered as unidimensional lanes. These unidimensional substrates are typically non-static: affected by a fluctuating environment, they can undergo conformational changes. This is particularly true in biological cells, where the state of the substrate is often coupled to the active motion of macromolecular complexes, such as motor proteins on microtubules or ribosomes on mRNAs, causing new interesting phenomena. Inspired by biological processes such as protein synthesis by ribosomes and motor protein transport, we introduce the concept of localized dynamical sites coupled to a driven lattice gas dynamics. We investigate the phenomenology of transport in the presence of dynamical defects and find a novel regime characterized by an intermittent current and subject to severe finite-size effects. Our results demonstrate the impact of the regulatory role of the dynamical defects in transport, not only in biology but also in more general contexts.

cond-mat.stat-mech

Driving kinetically constrained models into non-equilibrium steady states: structural and slow transport properties

Complex fluids in shear flow and biased dynamics in crowded environments exhibit counterintuitive features which are difficult to address both at theoretical level and by molecular dynamic simulations. To understand some of these features we study a schematic model of highly viscous liquid, the 2D Kob-Andersen kinetically constrained model, driven into non-equilibrium steady states by a uniform non-Hamiltonian force. We present a detailed numerical analysis of the microscopic behavior of the model, including transversal and longitudinal spatial correlations and dynamic heterogeneities. In particular, we show that at high particle density the transition from positive to negative resistance regimes in the current vs field relation can be explained via the emergence of nontrivial structures that intermittently trap the particles and slow down the dynamics. We relate such spatial structures to the current vs field relation in the different transport regimes.

cond-mat.soft

Dynamical heterogeneities in a two dimensional driven glassy model: current fluctuations and finite size effects

In this article, we demonstrate that in a transport model of particles with kinetic constraints, long-lived spatial structures are responsible for the blocking dynamics and the decrease of the current at strong driving field. Coexistence between mobile and blocked regions can be anticipated by a first-order transition in the large deviation function for the current. By a study of the system under confinement, we are able to study finite-size effects and extract a typical length between mobile regions.

cond-mat.dis-nn

Dynamic transition in an atomic glass former: a molecular dynamics evidence

We find that a Lennard-Jones mixture displays a dynamic phase transition between an active regime and an inactive one. By means of molecular dynamics simulations and of a finite-size study, we show that the space time dynamics in the supercooled regime coincides with a dynamic first order transition point.

cond-mat.stat-mech

Large deviations and heterogeneities in a driven kinetically constrained model

Kinetically Constrained Models (KCMs) have been widely studied in the context of glassy dynamics, focusing on the influence of dynamical constraints on the slowing down of the dynamics of a macroscopic system. In these models, it has been shown using the thermodynamic formalism for histories, that there is a coexistence between an active and an inactive phase. This coexistence can be described by a first-order transition, and a related discontinuity in the derivative of the large deviation function for the activity. We show that adding a driving field to a KCM model does not destroy this first-order transition for the activity. Moreover, a singularity is also found in the large deviation function of the current at large fields. We relate for the first time this property to microscopic structures, in particular the heterogeneous, intermittent dynamics of the particles, transient shear-banding and blocking walls. We describe both the shear-thinning and the shear-thickening regimes, and find that the behaviour of the current is well reproduced by a simple model.

cond-mat.dis-nn

Injected Power Fluctuations in 1D dissipative systems : role of ballistic transport

This paper is a generalization of the models considered in [J. Stat. Phys. 128,1365 (2007)]. Using an analogy with free fermions, we compute exactly the large deviation function (ldf) of the energy injected up to time $t$ in a one-dimensional dissipative system of classical spins, where a drift is allowed. The dynamics are T=0 asymmetric Glauber dynamics driven out of rest by an injection mechanism, namely a Poissonian flipping of one spin. The drift induces anisotropy in the system, making the model more comparable to experimental systems with dissipative structures. We discuss the physical content of the results, specifically the influence of the rate of the Poisson injection process and the magnitude of the drift on the properties of the ldf. We also compare the results of this spin model to simple phenomenological models of energy injection (Poisson or Bernoulli processes of domain wall injection). We show that many qualitative results of the spin model can be understood within this simplified framework.

cond-mat.stat-mech

Investigation of $q$-dependent dynamical heterogeneity in a colloidal gel by x-ray photon correlation spectroscopy

We use time-resolved X-Photon Correlation Spectroscopy to investigate the slow dynamics of colloidal gels made of moderately attractive carbon black particles. We show that the slow dynamics is temporally heterogeneous and quantify its fluctuations by measuring the variance $χ$ of the instantaneous intensity correlation function. The amplitude of dynamical fluctuations has a non-monotonic dependence on scattering vector $q$, in stark contrast with recent experiments on strongly attractive colloidal gels [Duri and Cipelletti, \textit{Europhys. Lett.} \textbf{76}, 972 (2006)]. We propose a simple scaling argument for the $q$-dependence of fluctuations in glassy systems that rationalizes these findings.

cond-mat.soft

Injected Power Fluctuations in 1D Dissipative Systems

Using fermionic techniques, we compute exactly the large deviation function (ldf) of the time-integrated injected power in several one-dimensional dissipative systems of classical spins. The dynamics are T=0 Glauber dynamics supplemented by an injection mechanism, which is taken as a Poissonian flipping of one particular spin. We discuss the physical content of the results, specifically the influence of the rate of the Poisson process on the properties of the ldf.

cond-mat.stat-mech

Finite-size effects and intermittency in a simple aging system

We study the intermittent dynamics and the fluctuations of the dynamic correlation function of a simple aging system. Given its size $L$ and its coherence length $ξ$, the system can be divided into $N$ independent subsystems, where $N=(\frac{L}ξ)^d$, and $d$ is the dimension of space. Each of them is considered as an aging subsystem which evolves according to an activated dynamics between energy levels. We compute analytically the distribution of trapping times for the global system, which can take power-law, stretched-exponential or exponential forms according to the values of $N$ and the regime of times considered. An effective number of subsystems at age $t_w$, $N_{eff}(t_w)$, can be defined, which decreases as $t_w$ increases, as well as an effective coherence length, $ξ(t_w) \sim t_w^{(1-μ)/d}$, where $μ<1$ characterizes the trapping times distribution of a single subsystem. We also compute the probability distribution functions of the time intervals between large decorrelations, which exhibit different power-law behaviours as $t_w$ increases (or $N$ decreases), and which should be accessible experimentally. Finally, we calculate the probability distribution function of the two-time correlator. We show that in a phenomenological approach, where $N$ is replaced by the effective number of subsystems $N_{eff}(t_w)$, the same qualitative behaviour as in experiments and simulations of several glassy systems can be obtained.

cond-mat.dis-nn

Spatial correlations in the relaxation of the Kob-Andersen model

We describe spatio-temporal correlations and heterogeneities in a kinetically constrained glassy model, the Kob-Andersen model. The kinetic constraints of the model alone induce the existence of dynamic correlation lengths, that increase as the density $ρ$ increases, in a way compatible with a double-exponential law. We characterize in detail the trapping time correlation length, the cooperativity length, and the distribution of persistent clusters of particles. This last quantity is related to the typical size of blocked clusters that slow down the dynamics for a given density.

cond-mat.dis-nn

Glassy behavior of a homopolymer from molecular dynamics simulations

We study at- and out-of-equilibrium dynamics of a single homopolymer chain at low temperature using molecular dynamics simulations. The main quantities of interest are the average root mean square displacement of the monomers below the theta point, and the structure factor, as a function of time. The observation of these quantities show a close resemblance to those measured in structural glasses and suggest that the polymer chain in its low temperature phase is in a glassy phase, with its dynamics dominated by traps. In equilibrium, at low temperature, we observe the trapping of the monomers and a slowing down of the overall motion of the polymer as well as non-exponential relaxation of the structure factor. In out-of-equilibrium, at low temperatures, we compute the two-time quantities and observe breaking of ergodicity in a range of waiting times, with the onset of aging.

cond-mat.soft

Mode-coupling theory for heteropolymers

We study the Langevin dynamics of a heteropolymer by means of a mode-coupling approximation scheme, giving rise to a set of coupled integro-differential equations relating the response and correlation functions. The analysis shows that there is a regime at low temperature characterized by out-of-equilibrium dynamics, with violation of time-translational invariance and of the fluctuation-dissipation theorem. The onset of ageing dynamics at low temperatures gives new insight into the nature of the slow dynamics of a disordered polymer. We also introduce a renormalization-group treatment of our mode-coupling equations, which supports our analysis, and might be applicable to other systems.

cond-mat.dis-nn

The role of the energy gap in protein folding dynamics

The dynamics of folding of proteins is studied by means of a phenomenological master equation. The energy distribution is taken as a truncated exponential for the misfolded states plus a native state sitting below the continuum. The influence of the gap on the folding dynamics is studied, for various models of the transition probabilities between the different states of the protein. We show that for certain models, the relaxation to the native state is accelerated by increasing the gap, whereas for others it is slowed down .

cond-mat.soft