arXiv subjects

Eugene Kashdan

Publications and source records attributed to Eugene Kashdan.

4 recordsLinked to original sources

arXiv2020

Performance analysis of Volna-OP2 -- massively parallel code for tsunami modelling

The software package Volna-OP2 is a robust and efficient code capable of simulating the complete life cycle of a tsunami whilst harnessing the latest High Performance Computing (HPC) architectures. In this paper, a comprehensive error analysis and scalability study of the GPU version of the code is presented. A novel decomposition of the numerical errors into the dispersion and dissipation components is explored. Most tsunami codes exhibit amplitude smearing and/or phase lagging/leading, so the decomposition shown here is a new approach and novel tool for explaining these occurrences. It is the first time that the errors of a tsunami code have been assessed in this manner. To date, Volna-OP2 has been widely used by the tsunami modelling community. In particular its computational efficiency has allowed various sensitivity analyses and uncertainty quantification studies. Due to the number of simulations required, there is always a trade-off between accuracy and runtime when carrying out these statistical studies. The analysis presented in this paper will guide the user towards an acceptable level of accuracy within a given runtime.

physics.comp-ph↗

arXiv2014

Modeling and simulation of a low grade urinary bladder carcinoma

In this work, we present a mathematical model of the initiation and progression of a low-grade urinary bladder carcinoma. We simulate the crucial processes involved in tumor growth, such as oxygen diffusion, carcinogen penetration, and angiogenesis, within the framework of the urothelial cell dynamics. The cell dynamics are modeled using the discrete technique of Cellular Automata, while the continuous processes of carcinogen penetration and oxygen diffusion are described by nonlinear diffusion-absorption equations. As the availability of oxygen is necessary for tumor progression, processes of oxygen transport to the tumor growth site seem most important. Our model yields a theoretical insight into the main stages of development and growth of urinary bladder carcinoma with emphasis on two most common types: bladder polyps and carcinoma {\it in situ}. Analysis of histological structure of bladder tumor is important to avoid misdiagnosis and wrong treatment and we expect our model to be a valuable tool in the prediction of tumor grade and progression patterns, based on the exposure to carcinogens and an oxygen dependent expression of genes promoting tumor growth. Our numerical simulations have good qualitative agreement with {\it in vivo} results reported in the corresponding medical literature.

q-bio.QM↗

arXiv2013

Simulation of Electromagnetic Scattering with Stationary or Accelerating Targets

The scattering of electromagnetic waves by an obstacle is analyzed through a set of partial differential equations combining the Maxwell's model with the mechanics of fluids. Solitary type EM waves, having compact support, may easily be modeled in this context since they turn out to be explicit solutions. From the numerical viewpoint, the interaction of these waves with a material body is examined. Computations are carried out via a parallel high-order finite-differences code. Due to the presence of a gradient of pressure in the model equations, waves hitting the obstacle may impart acceleration to it. Some explicative 2D dynamical configurations are then studied, enabling the study of photon-particle iterations through classical arguments.

physics.comp-ph↗

arXiv2011

Mean field mutation dynamics and the continuous Luria-Delbrück distribution

The Luria-Delbrück mutation model has a long history and has been mathematically formulated in several different ways. Here we tackle the problem in the case of a continuous distribution using some mathematical tools from nonlinear statistical physics. Starting from the classical formulations we derive the corresponding differential models and show that under a suitable mean field scaling they correspond to generalized Fokker-Planck equations for the mutants distribution whose solutions are given by the corresponding Luria-Delbrück distribution. Numerical results confirming the theoretical analysis are also presented.

math-ph↗