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Fang Mei

Publications and source records attributed to Fang Mei.

6 recordsLinked to original sources

BRIGHT: A Collaborative Generalist-Specialist Foundation Model for Breast Pathology

Generalist pathology foundation models (PFMs), pretrained on large-scale multi-organ datasets, have demonstrated remarkable predictive capabilities across diverse clinical applications. However, their proficiency on the full spectrum of clinically essential tasks within a specific organ system remains an open question due to the lack of large-scale validation cohorts for a single organ as well as the absence of a tailored training paradigm that can effectively translate broad histomorphological knowledge into the organ-specific expertise required for specialist-level interpretation. In this study, we propose BRIGHT, the first PFM specifically designed for breast pathology, trained on over 51,000 breast whole-slide images derived from a cohort of over 40,000 patients across 19 hospitals. BRIGHT employs a collaborative generalist-specialist framework to capture both universal and organ-specific features. To comprehensively evaluate the performance of PFMs on breast oncology, we curate the largest multi-institutional cohorts to date for downstream task development and evaluation, comprising over 25,000 WSIs across 10 hospitals. The validation cohorts cover the full spectrum of breast pathology across 25 distinct clinical tasks spanning diagnosis, biomarker prediction, treatment response and survival prediction. Extensive experiments demonstrate that BRIGHT outperforms five leading generalist PFMs, achieving state-of-the-art (SOTA) performance in 25 of 25 internal validation tasks and in 4 of 11 external validation tasks with excellent heatmap interpretability. By evaluating on large-scale validation cohorts, this study not only demonstrates BRIGHT's clinical utility in breast oncology but also validates a collaborative generalist-specialist paradigm, providing a scalable template for developing PFMs on a specific organ system, accelerating the translation of foundation models into ...

cs.CV

Securing the Sky: Integrated Satellite-UAV Physical Layer Security for Low-Altitude Wireless Networks

Low-altitude wireless networks (LAWNs) have garnered significant attention in the forthcoming 6G networks. In LAWNs, satellites with wide coverage and unmanned aerial vehicles (UAVs) with flexible mobility can complement each other to form integrated satellite-UAV networks, providing ubiquitous and high-speed connectivity for low-altitude operations. However, the higher line-of-sight probability in low-altitude airspace increases transmission security concerns. In this work, we present a collaborative beamforming-based physical layer security scheme for LAWNs. We introduce the fundamental aspects of integrated satellite-UAV networks, physical layer security, UAV swarms, and collaborative beamforming for LAWN applications. Following this, we highlight several opportunities for collaborative UAV swarm secure applications enabled by satellite networks, including achieving physical layer security in scenarios involving data dissemination, data relay, eavesdropper collusion, and imperfect eavesdropper information. Next, we detail two case studies: a secure relay system and a two-way aerial secure communication framework specifically designed for LAWN environments. Simulation results demonstrate that these physical layer security schemes are effective and beneficial for secure low-altitude wireless communications. A short practicality analysis shows that the proposed method is applicable to LAWN scenarios. Finally, we discuss current challenges and future research directions for enhancing security in LAWNs.

cs.NI

HSI: A Holistic Style Injector for Arbitrary Style Transfer

Attention-based arbitrary style transfer methods have gained significant attention recently due to their impressive ability to synthesize style details. However, the point-wise matching within the attention mechanism may overly focus on local patterns such that neglect the remarkable global features of style images. Additionally, when processing large images, the quadratic complexity of the attention mechanism will bring high computational load. To alleviate above problems, we propose Holistic Style Injector (HSI), a novel attention-style transformation module to deliver artistic expression of target style. Specifically, HSI performs stylization only based on global style representation that is more in line with the characteristics of style transfer, to avoid generating local disharmonious patterns in stylized images. Moreover, we propose a dual relation learning mechanism inside the HSI to dynamically render images by leveraging semantic similarity in content and style, ensuring the stylized images preserve the original content and improve style fidelity. Note that the proposed HSI achieves linear computational complexity because it establishes feature mapping through element-wise multiplication rather than matrix multiplication. Qualitative and quantitative results demonstrate that our method outperforms state-of-the-art approaches in both effectiveness and efficiency.

cs.CV

Generative AI for Deep Reinforcement Learning: Framework, Analysis, and Use Cases

As a form of artificial intelligence (AI) technology based on interactive learning, deep reinforcement learning (DRL) has been widely applied across various fields and has achieved remarkable accomplishments. However, DRL faces certain limitations, including low sample efficiency and poor generalization. Therefore, we present how to leverage generative AI (GAI) to address these issues above and enhance the performance of DRL algorithms in this paper. We first introduce several classic GAI and DRL algorithms and demonstrate the applications of GAI-enhanced DRL algorithms. Then, we discuss how to use GAI to improve DRL algorithms from the data and policy perspectives. Subsequently, we introduce a framework that demonstrates an actual and novel integration of GAI with DRL, i.e., GAI-enhanced DRL. Additionally, we provide a case study of the framework on UAV-assisted integrated near-field/far-field communication to validate the performance of the proposed framework. Moreover, we present several future directions. Finally, the related code is available at: https://xiewenwen22.github.io/GAI-enhanced-DRL.

cs.LG

Generative AI for Game Theory-based Mobile Networking

With the continuous advancement of network technology, various emerging complex networking optimization problems have created a wide range of applications utilizing game theory. However, since game theory is a mathematical framework, game theory-based solutions often rely heavily on the experience and knowledge of human experts. Recently, the remarkable advantages exhibited by generative artificial intelligence (GAI) have gained widespread attention. In this work, we propose a novel GAI-enabled game theory solution that combines the powerful reasoning and generation capabilities of GAI to the design and optimization of mobile networking. Specifically, we first outline the game theory and key technologies of GAI, and explore the advantages of combining GAI with game theory. Then, we review the contributions and limitations of existing research and demonstrate the potential application values of GAI applied to game theory in mobile networking. Subsequently, we develop a large language model (LLM)-enabled game theory framework to realize this combination, and demonstrate the effectiveness of the proposed framework through a case study in secured UAV networks. Finally, we provide several directions for future extensions.

cs.GT

A Two Time-Scale Joint Optimization Approach for UAV-assisted MEC

Unmanned aerial vehicles (UAV)-assisted mobile edge computing (MEC) is emerging as a promising paradigm to provide aerial-terrestrial computing services close to mobile devices (MDs). However, meeting the demands of computation-intensive and delay-sensitive tasks for MDs poses several challenges, including the demand-supply contradiction between MDs and MEC servers, the demand-supply heterogeneity between MDs and MEC servers, the trajectory control requirements on energy efficiency and timeliness, and the different time-scale dynamics of the network. To address these issues, we first present a hierarchical architecture by incorporating terrestrial-aerial computing capabilities and leveraging UAV flexibility. Furthermore, we formulate a joint computing resource allocation, computation offloading, and trajectory control problem to maximize the system utility. Since the problem is a non-convex mixed integer nonlinear programming (MINLP), we propose a two time-scale joint computing resource allocation, computation offloading, and trajectory control (TJCCT) approach. In the short time scale, we propose a price-incentive method for on-demand computing resource allocation and a matching mechanism-based method for computation offloading. In the long time scale, we propose a convex optimization-based method for UAV trajectory control. Besides, we prove the stability, optimality, and polynomial complexity of TJCCT. Simulation results demonstrate that TJCCT outperforms the comparative algorithms in terms of the utility of the system, the QoE of MDs, and the revenue of MEC servers.

eess.SY