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Fangyu Zhou

Publications and source records attributed to Fangyu Zhou.

3 recordsLinked to original sources

Subgraph Filtering for Fair Graph Neural Networks

Graph neural networks (GNNs) can exhibit unfair behavior even when sensitive attributes are excluded from node features, because graph topology and message passing propagate group-correlated signals under sensitive homophily. Existing fairness-aware GNN methods mainly constrain representations or prediction distributions at a global level, without explicitly controlling the local structural pathways through which biased information propagates during aggregation. We propose Subgraph Filtering for Fair Graph Neural Networks (SF-GNN), a lightweight and architecture-agnostic framework that mitigates structural bias at its source. SF-GNN identifies bias-prone edges by combining sensitive homophily with structural propagation amplifiers, including hub participation and triadic closure. It then incorporates stochastic edge filtering into each message-passing step to selectively downweight or remove these edges while preserving the remaining graph structure. Training further incorporates a statistical-parity regularizer with a warm-up schedule to stabilize optimization. Experiments on five benchmark datasets show that SF-GNN achieves consistent fairness improvements while maintaining competitive predictive performance, leading to a better fairness--accuracy trade-off than recent fairness-aware GNN baselines.

cs.LG

Libra-MIL: Multimodal Prototypes Stereoscopic Infused with Task-specific Language Priors for Few-shot Whole Slide Image Classification

While Large Language Models (LLMs) are emerging as a promising direction in computational pathology, the substantial computational cost of giga-pixel Whole Slide Images (WSIs) necessitates the use of Multi-Instance Learning (MIL) to enable effective modeling. A key challenge is that pathological tasks typically provide only bag-level labels, while instance-level descriptions generated by LLMs often suffer from bias due to a lack of fine-grained medical knowledge. To address this, we propose that constructing task-specific pathological entity prototypes is crucial for learning generalizable features and enhancing model interpretability. Furthermore, existing vision-language MIL methods often employ unidirectional guidance, limiting cross-modal synergy. In this paper, we introduce a novel approach, Multimodal Prototype-based Multi-Instance Learning, that promotes bidirectional interaction through a balanced information compression scheme. Specifically, we leverage a frozen LLM to generate task-specific pathological entity descriptions, which are learned as text prototypes. Concurrently, the vision branch learns instance-level prototypes to mitigate the model's reliance on redundant data. For the fusion stage, we employ the Stereoscopic Optimal Transport (SOT) algorithm, which is based on a similarity metric, thereby facilitating broader semantic alignment in a higher-dimensional space. We conduct few-shot classification and explainability experiments on three distinct cancer datasets, and the results demonstrate the superior generalization capabilities of our proposed method.

cs.CV

Dynamic Entity-Masked Graph Diffusion Model for histopathological image Representation Learning

Significant disparities between the features of natural images and those inherent to histopathological images make it challenging to directly apply and transfer pre-trained models from natural images to histopathology tasks. Moreover, the frequent lack of annotations in histopathology patch images has driven researchers to explore self-supervised learning methods like mask reconstruction for learning representations from large amounts of unlabeled data. Crucially, previous mask-based efforts in self-supervised learning have often overlooked the spatial interactions among entities, which are essential for constructing accurate representations of pathological entities. To address these challenges, constructing graphs of entities is a promising approach. In addition, the diffusion reconstruction strategy has recently shown superior performance through its random intensity noise addition technique to enhance the robust learned representation. Therefore, we introduce H-MGDM, a novel self-supervised Histopathology image representation learning method through the Dynamic Entity-Masked Graph Diffusion Model. Specifically, we propose to use complementary subgraphs as latent diffusion conditions and self-supervised targets respectively during pre-training. We note that the graph can embed entities' topological relationships and enhance representation. Dynamic conditions and targets can improve pathological fine reconstruction. Our model has conducted pretraining experiments on three large histopathological datasets. The advanced predictive performance and interpretability of H-MGDM are clearly evaluated on comprehensive downstream tasks such as classification and survival analysis on six datasets. Our code will be publicly available at https://github.com/centurion-crawler/H-MGDM.

cs.CV