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Faraz Hach

Publications and source records attributed to Faraz Hach.

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Anomaly Factory 3D: A Modular Framework for Diverse Pseudo-Anomaly Synthesis in Unsupervised 3D Anomaly Detection

Detecting and localizing defects in 3D point clouds is challenging because abnormal samples are scarce and diverse, while training is often limited to normal data. We propose Anomaly Factory 3D (AF3AD), a modular framework that synthesizes diverse pseudo-anomalies from normal point clouds to expand the training data for unsupervised 3D anomaly detection methods that rely on pseudo-anomalies. AF3AD uses a center-conditioned parametric deformation model defined in local PCA frames, with kernel-controlled spatial falloff, anisotropy, directional gating, and normal/tangential displacement fields, enabling a broad set of geometric defect presets. We demonstrate its ease-of-use and effectiveness by integrating AF3AD with an offset-prediction detector and a reconstruction-based anomaly detection method, showing that AF3AD transfers across detection paradigms. Experiments on AnomalyShapeNet and Real3D-AD show consistent improvements in object- and point-level detection and localization, supported by ablations on preset groups and robustness under noise. AF3AD is designed as a standalone synthesis tool to facilitate adoption across different 3D anomaly detection paradigms. Code is available at github.com/vpc-ccg/AF3AD.

cs.CV

Fast Characterization of Segmental Duplications in Genome Assemblies

Segmental duplications (SDs), or low-copy repeats (LCR), are segments of DNA greater than 1 Kbp with high sequence identity that are copied to other regions of the genome. SDs are among the most important sources of evolution, a common cause of genomic structural variation, and several are associated with diseases of genomic origin. Despite their functional importance, SDs present one of the major hurdles for de novo genome assembly due to the ambiguity they cause in building and traversing both state-of-the-art overlap-layout-consensus and de Bruijn graphs. This causes SD regions to be misassembled, collapsed into a unique representation, or completely missing from assembled reference genomes for various organisms. In turn, this missing or incorrect information limits our ability to fully understand the evolution and the architecture of the genomes. Despite the essential need to accurately characterize SDs in assemblies, there is only one tool that has been developed for this purpose, called Whole Genome Assembly Comparison (WGAC). WGAC is comprised of several steps that employ different tools and custom scripts, which makes it difficult and time consuming to use. Thus there is still a need for algorithms to characterize within-assembly SDs quickly, accurately, and in a user friendly manner. Here we introduce a SEgmental Duplication Evaluation Framework (SEDEF) to rapidly detect SDs through sophisticated filtering strategies based on Jaccard similarity and local chaining. We show that SEDEF accurately detects SDs while maintaining substantial speed up over WGAC that translates into practical run times of minutes instead of weeks. Notably, our algorithm captures up to 25% pairwise error between segments, where previous studies focused on only 10%, allowing us to more deeply track the evolutionary history of the genome. SEDEF is available at https://github.com/vpc-ccg/sedef

cs.DS