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Farzan Siddiqui

Publications and source records attributed to Farzan Siddiqui.

2 recordsLinked to original sources

What Language Models Know But Don't Say: Non-Generative Prior Extraction for Generalization

In domains like medicine and finance, large-scale labeled data is costly and often unavailable, leading to models trained on small datasets that struggle to generalize to real-world populations. Large language models contain extensive knowledge from years of research across these domains. We propose LoID (Logit-Informed Distributions), a deterministic method for extracting informative prior distributions for Bayesian logistic regression by directly accessing their token-level predictions. Rather than relying on generated text, we probe the model's confidence in opposing semantic directions (positive vs. negative impact) through carefully constructed sentences. By measuring how consistently the LLM favors one direction across diverse phrasings, we extract the strength and reliability of the model's belief about each feature's influence. We evaluate LoID on ten real-world tabular datasets under synthetic out-of-distribution (OOD) settings characterized by covariate shift, where the training data represents only a subset of the population. We compare our approach against (1) standard uninformative priors, (2) AutoElicit, a recent method that prompts LLMs to generate priors via text completions, (3) LLMProcesses, a method that uses LLMs to generate numerical predictions through in-context learning and (4) an oracle-style upper bound derived from fitting logistic regression on the full dataset. We assess performance using Area Under the Curve (AUC). Across datasets, LoID significantly improves performance over logistic regression trained on OOD data, recovering up to \textbf{59\%} of the performance gap relative to the oracle model. LoID outperforms AutoElicit and LLMProcessesc on 8 out of 10 datasets, while providing a reproducible and computationally efficient mechanism for integrating LLM knowledge into Bayesian inference.

cs.CL↗

An Introduction to Natural Language Processing Techniques and Framework for Clinical Implementation in Radiation Oncology

Natural Language Processing (NLP) is a key technique for developing Medical Artificial Intelligence (AI) systems that leverage Electronic Health Record (EHR) data to build diagnostic and prognostic models. NLP enables the conversion of unstructured clinical text into structured data that can be fed into AI algorithms. The emergence of the transformer architecture and large language models (LLMs) has led to remarkable advances in NLP for various healthcare tasks, such as entity recognition, relation extraction, sentence similarity, text summarization, and question answering. In this article, we review the major technical innovations that underpin modern NLP models and present state-of-the-art NLP applications that employ LLMs in radiation oncology research. However, these LLMs are prone to many errors such as hallucinations, biases, and ethical violations, which necessitate rigorous evaluation and validation before clinical deployment. As such, we propose a comprehensive framework for assessing the NLP models based on their purpose and clinical fit, technical performance, bias and trust, legal and ethical implications, and quality assurance, prior to implementation in clinical radiation oncology. Our article aims to provide guidance and insights for researchers and clinicians who are interested in developing and using NLP models in clinical radiation oncology.

cs.CL↗