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Fatima Rani

Publications and source records attributed to Fatima Rani.

3 recordsLinked to original sources

Synthetic Biological Intelligence: System-Level Abstractions and Adaptive Bio-Digital Interaction

Concurrent advances across fields such as organoid technology, Microelectrode Arrays (MEAs), neuromorphic computing, and machine learning have given rise to a groundbreaking research paradigm: Synthetic Biological Intelligence (SBI). SBI refers to engineered systems in which living Biological Neural Networks (BNNs) are interfaced with hardware and software to perform task-oriented information processing in a closed loop. This cutting-edge technology, while still in its infancy, has the potential to deliver highly efficient performance across both computing capabilities and energy consumption. The early stage of this field underscores the need for reliable multi-scale and cross-domain interaction interfaces to support applications in robotics, biomedicine, signal processing, and neuroscience research. The hitherto lack of commercially available SBI platforms has slowed the development, as the conditions to produce a testbed are expensive and cumbersome. The introduction of standardized, platform- and cloud-integrated BNNs has been a crucial catalyst for the scientific community, improving the accessibility of SBI and leading the way to further developments. In this survey, we summarize the innovations that contributed to the emergence of SBI and the first testbed interfaces that enabled its embodiment. This work reframes SBI as a bio-digital interaction system and introduces a unified protocol across encoding, decoding, system engineering, and benchmarking.

cs.ET

Modulation, ISI, and Detection for Langmuir Adsorption-Based Microfluidic Molecular Communication

This paper studies microfluidic molecular communication receivers with finite-capacity Langmuir adsorption driven by an effective surface concentration. In the reaction-limited regime, we derive a closed-form single-pulse response kernel and a symbol-rate recursion for on-off keying that explicitly exposes channel memory and inter-symbol interference. We further develop short-pulse and long-pulse approximations, revealing an interference asymmetry in the long-pulse regime due to saturation. To account for stochasticity, we adopt a finite-receptor binomial counting model, employ pulse-end sampling, and propose a low-complexity midpoint-threshold detector that reduces to a fixed threshold when interference is negligible. Numerical results corroborate the proposed characterization and quantify detection performance versus pulse and symbol durations.

eess.SP

System Modeling of Microfluidic Molecular Communication: A Markov Approach

This paper presents a Markov-based system model for microfluidic molecular communication (MC) channels. By discretizing the advection-diffusion dynamics, the proposed model establishes a physically consistent state-space formulation. The transition matrix explicitly captures diffusion, advective flow, reversible binding, and flow-out effects. The resulting discrete-time formulation enables analytical characterization of both transient and equilibrium responses through a linear system representation. Numerical results verify that the proposed framework accurately reproduces channel behaviors across a wide range of flow conditions, providing a tractable basis for the design and analysis of MC systems in microfluidic environments.

cs.ET