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Feifei Wang

Publications and source records attributed to Feifei Wang.

At least 19 recordsLinked to original sources

Agentic AI-powered flexible fiber-bundle endoscopy for high-resolution NIR-II fluorescence imaging in vivo

Fiber-bundle endoscopy offers a compact and flexible route for clinical fluorescence imaging through natural human orifices, but since its first report in the 1950s, it has remained limited by low spatial resolution, honeycomb artifacts, and inter-core crosstalk. The crosstalk becomes more pronounced at near-infrared-II wavelengths (NIR-II, 1000-3000 nm), a spectral window that offers superior contrast, resolution, and tissue penetration depth for biomedical imaging. Here, we present an AI-powered flexible endoscopy platform that overcomes these constraints through optical-computational co-design: optimizing ultrathin fiber bundles to mitigate crosstalk-induced image blur and enable high-fidelity image transmission across the visible-to-NIR-II spectral range, and developing an Agent-Guided Mixture-of-Experts (GAME) pipeline for honeycomb-artifact removal and image restoration. GAME provides a single restoration entry point for diverse biomedical images acquired with our endoscope, spanning cell, mouse and human samples. It dynamically routes each input to suitable restoration experts via a vision-language model, facilitating image reconstruction with a fourfold resolution improvement beyond the NyquistShannon sampling limit. The utility of our endoscope is demonstrated through in vivo NIR-II imaging of anatomical structures in mice, as well as imaging of the digital micromirror device (DMD)-projected human gastric tube and lymphatic system, paving the way for future clinical translation.

cs.CV

CoNav-UAV: Cooperative Dual-Altitude Aerial Navigation via Stackelberg Learning

Target-oriented vision-and-language navigation (VLN) on aerial platforms is attracting growing attention for missions such as disaster rescue, infrastructure inspection, and security patrol. In this task, an unmanned aerial vehicle (UAV) needs to locate targets given only a concise description of their appearance and surroundings. This requires global exploration and grounding as well as collision-free close-range approach, two interleaved processes difficult to reconcile within a single agent. Most existing methods transfer the ground VLN paradigm to a low-altitude UAV and compensate for its inefficient exploration with external assistance. A recent attempt deploys two UAVs at complementary altitudes yet still relies on privileged information and trains its two agents independently, precluding any mutual adaptation essential for cooperation. Here we propose CoNav-UAV, which explicitly models the task as a Stackelberg game between a high-altitude leader and a low-altitude follower, with the system operating on onboard visual and linguistic inputs alone. To solve this game, we introduce Iterative Stackelberg Learning. The leader's high-level vision-language reasoning is refined via memory-based in-context learning, while the follower's precise motion control is updated via DAgger-style expert distillation. The alternation drives both agents toward a Stackelberg equilibrium. CoNav-UAV consistently outperforms single- and dual-agent baselines across three high-fidelity urban scenes from the AerialVLN benchmark. Success rate improves by up to 30.8 points on the learning scene, and 9.0 points under cross-scene transfer while using about 3x less adaptation data. Further analyses validate the complementary gains of the leader and follower updates and reveal robust gains yet distinct learning dynamics across VLM backbones.

cs.AI

BoxCtrl: 3D-Aware Visual Prompting for Geometric Image Editing

As instruction-based editing models and multimodal large language models advance, diverse image editing tasks have become feasible. However, achieving precise and consistent geometric image editing, such as translating, scaling, and rotating in 3D space, remains a major challenge. In this work, we introduce BoxCtrl, a 3D-aware visual prompting framework. Unlike text-only or coarse 2D-guided approaches, our method introduces informative RGB 3D bounding boxes projected onto 2D images as visual prompts. The three orthogonal faces of each box are painted with distinct RGB colors, simultaneously encoding position, size, and orientation to provide a compact, intuitive in-context visual example. The key to BoxCtrl's success lies in these well-designed bounding boxes, which decouple geometric control from appearance control. This enables the model to learn consistent correspondences between faces of the same color in the latent space, leading to a precise understanding of geometric intentions and accurate editing results. We introduce a two-stage training paradigm: Supervised Fine-Tuning (SFT) followed by Reinforcement Learning (RL). To address paired data scarcity, we construct a large-scale synthetic dataset for SFT, equipping the model with fundamental editing capabilities. To bridge the synthetic-to-real domain gap, we incorporate an online RL stage leveraging unpaired real-world data. Guided by a reward function evaluating geometric accuracy and visual fidelity, our SFT-RL strategy significantly enhances geometric precision while maintaining photorealistic quality. Extensive experiments demonstrate that BoxCtrl achieves state-of-the-art performance across translation, rotation, scaling, and composite editing tasks.

cs.CV

A Pathology Foundation Model for Gastric Cancer with Real-World Validation

Gastric cancer remains a major cause of cancer mortality, yet its histological and molecular heterogeneity complicates diagnosis and risk stratification. General-purpose pathology foundation models (PFMs) often plateau on fine-grained endpoints central to gastric cancer care, and few have undergone rigorous prospective validation or clinical reader studies. We present GRACE, a Gastric-specific foundation model for Real-world Assessment and Clinical dEcision support. GRACE was developed from multicenter gastric pathology datasets totaling 48,364 primarily HE-stained whole-slide images from 37,493 patients. When evaluated on 28 clinically relevant tasks, GRACE consistently outperformed representative pancancer PFMs, achieving a macro-AUC of 0.9188, with strong performance for precancerous lesion diagnosis (macro-AUC 0.9322), tumor histopathological assessment (macro-AUC 0.9119), molecular profiling (macro-AUC 0.8682), and prognostic prediction. Beyond benchmarking, GRACE's translational value was substantiated through a rigorous evidence chain. Under safety-gated criteria requiring 100% NPV for rule-out and 100% PPV for rule-in, GRACE streamlined review for up to 69.6% of malignancy-diagnosis cases and triaged 46.8% of MMR-IHC follow-up requests. This translational feasibility was further strengthened by a randomized crossover reader study of pathologist-AI collaboration. With GRACE assistance, diagnostic accuracy improved from 82.0% to 89.9%, yielding nearly twofold higher adjusted odds of a correct diagnosis (OR 1.987) alongside concurrent gains in sensitivity and specificity. AI assistance also reduced diagnostic time by 14.9%, elevated diagnostic confidence by 9.0%, and markedly improved inter-rater agreement. When calibrated to maintain non-inferior performance to senior pathologists, the AI-assisted workflow could triage 60.7% of atrophy and 82.7% of intestinal metaplasia cases.

cs.CV

Decoupled Residual Denoising Diffusion Models for Unified and Data Efficient Image-to-Image Translation

We propose Decoupled Residual Denoising Diffusion models (DRDD) for unified and data-efficient image-to-image (I2I) translation. While diffusion models have advanced I2I translation in terms of quality and diversity, we uncover a previously under-explored property in diffusion models. Crucially, beyond its conventional role of manifold lifting (i.e., moving data off low-dimensional manifolds), injecting Gaussian noise facilitates domain harmonization by implicitly aligning feature distributions across domains, a property particularly advantageous for unified I2I translation. However, existing diffusion models prematurely erode this harmonization effect, as noise and residuals are simultaneously removed in a single coupled diffusion process. To address this, DRDD decouples the diffusion process into two sequential and independent diffusion stages: (1) a stochastic noise diffusion for domain harmonization and manifold lifting, and (2) a deterministic residual diffusion that learns the core semantic mapping entirely within the fixed-noise domain. This decoupling preserves harmonization and manifold lifting effects throughout the transformation, substantially simplifying the learning of unified mappings across diverse tasks and domains. Notably, the noise diffusion stage is trained exclusively on abundant, unpaired target-domain images, greatly improving data efficiency. Comprehensive theoretical and empirical analysis demonstrates that DRDD is broadly compatible with mainstream diffusion models and consistently delivers robust, unified I2I translation, even under limited paired data. Our code is available at https://github.com/HKU-HealthAI/DRDD.

cs.CV

Spin Elasticity:A New Paradigm for Spintronics

Elasticity shapes our world. For centuries, it has been regarded as a property exclusive to ordinary matter. Here we uncover its hidden existence in the spin degree of freedom. We introduce spin elasticity-a framework linking spin torque to spin morpgology. This reveals a topological Hooke's law, uncovers spontaneous oscillations and resonance, and predicts a new class of collective excitations:spin stress waves. By establishing a unfied tau-D theory bridging classical elasticity and topological spin physics, this work completes the elastic picture and opens a new frontier for spintronics-spinelastronics.

cond-mat.mes-hall

Spin Elasticity

Elasticity has long been regarded as a property exclusive to material media. Here we uncover its hidden existence in the spin degree of freedom. We introduce spin elasticity-an intrinsic mechanism that governs recoverable deformation of spin morphology. This discovery reveals a previously unrecognized universality: elasticity operates in both matter and spin spaces, underpinning structural integrity across physical realms. By establishing the missing spin counterpart, this work completes the elastic picture and points toward a broader paradigm where elasticity transcends its conventional boundaries.

cond-mat.mes-hall

Enhancing Rare Codes via Probability-Biased Directed Graph Attention for Long-Tail ICD Coding

Automated international classification of diseases (ICD) coding aims to assign multiple disease codes to clinical documents and plays a critical role in healthcare informatics. However, its performance is hindered by the extreme long-tail distribution of the ICD ontology, where a few common codes dominate while thousands of rare codes have very few examples. To address this issue, we propose a Probability-Biased Directed Graph Attention model (ProBias) that partitions codes into common and rare sets and allows information to flow only from common to rare codes. Edge weights are determined by conditional co-occurrence probabilities, which guide the attention mechanism to enrich rare-code representations with clinically related signals. To provide higher-quality semantic representations as model inputs, we further employ large language models to generate enriched textual descriptions for ICD codes, offering external clinical context that complements statistical co-occurrence signals. Applied to automated ICD coding, our approach significantly improves the representation and prediction of rare codes, achieving state-of-the-art performance on three benchmark datasets. In particular, we observe substantial gains in macro-averaged F1 score, a key metric for long-tail classification.

cs.LG

Exploring the Vulnerabilities of Federated Learning: A Deep Dive into Gradient Inversion Attacks

Federated Learning (FL) has emerged as a promising privacy-preserving collaborative model training paradigm without sharing raw data. However, recent studies have revealed that private information can still be leaked through shared gradient information and attacked by Gradient Inversion Attacks (GIA). While many GIA methods have been proposed, a detailed analysis, evaluation, and summary of these methods are still lacking. Although various survey papers summarize existing privacy attacks in FL, few studies have conducted extensive experiments to unveil the effectiveness of GIA and their associated limiting factors in this context. To fill this gap, we first undertake a systematic review of GIA and categorize existing methods into three types, i.e., \textit{optimization-based} GIA (OP-GIA), \textit{generation-based} GIA (GEN-GIA), and \textit{analytics-based} GIA (ANA-GIA). Then, we comprehensively analyze and evaluate the three types of GIA in FL, providing insights into the factors that influence their performance, practicality, and potential threats. Our findings indicate that OP-GIA is the most practical attack setting despite its unsatisfactory performance, while GEN-GIA has many dependencies and ANA-GIA is easily detectable, making them both impractical. Finally, we offer a three-stage defense pipeline to users when designing FL frameworks and protocols for better privacy protection and share some future research directions from the perspectives of attackers and defenders that we believe should be pursued. We hope that our study can help researchers design more robust FL frameworks to defend against these attacks.

cs.CR

Adaptive Decentralized Federated Learning for Robust Optimization

In decentralized federated learning (DFL), the presence of abnormal clients, often caused by noisy or poisoned data, can significantly disrupt the learning process and degrade the overall robustness of the model. Previous methods on this issue often require a sufficiently large number of normal neighboring clients or prior knowledge of reliable clients, which reduces the practical applicability of DFL. To address these limitations, we develop here a novel adaptive DFL (aDFL) approach for robust estimation. The key idea is to adaptively adjust the learning rates of clients. By assigning smaller rates to suspicious clients and larger rates to normal clients, aDFL mitigates the negative impact of abnormal clients on the global model in a fully adaptive way. Our theory does not put any stringent conditions on neighboring nodes and requires no prior knowledge. A rigorous convergence analysis is provided to guarantee the oracle property of aDFL. Extensive numerical experiments demonstrate the superior performance of the aDFL method.

cs.LG

Factor-Assisted Federated Learning for Personalized Optimization with Heterogeneous Data

Federated learning is an emerging distributed machine learning framework aiming at protecting data privacy. Data heterogeneity is one of the core challenges in federated learning, which could severely degrade the convergence rate and prediction performance of deep neural networks. To address this issue, we develop a novel personalized federated learning framework for heterogeneous data, which we refer to as FedSplit. This modeling framework is motivated by the finding that, data in different clients contain both common knowledge and personalized knowledge. Then the hidden elements in each neural layer can be split into the shared and personalized groups. With this decomposition, a novel objective function is established and optimized. We demonstrate FedSplit enjoyers a faster convergence speed than the standard federated learning method both theoretically and empirically. The generalization bound of the FedSplit method is also studied. To practically implement the proposed method on real datasets, factor analysis is introduced to facilitate the decoupling of hidden elements. This leads to a practically implemented model for FedSplit and we further refer to as FedFac. We demonstrated by simulation studies that, using factor analysis can well recover the underlying shared/personalized decomposition. The superior prediction performance of FedFac is further verified empirically by comparison with various state-of-the-art federated learning methods on several real datasets.

stat.ML

Enterprise Profit Prediction Using Multiple Data Sources with Missing Values through Vertical Federated Learning

Small and medium-sized enterprises (SMEs) play a crucial role in driving economic growth. Monitoring their financial performance and discovering relevant covariates are essential for risk assessment, business planning, and policy formulation. This paper focuses on predicting profits for SMEs. Two major challenges are faced in this study: 1) SMEs data are stored across different institutions, and centralized analysis is restricted due to data security concerns; 2) data from various institutions contain different levels of missing values, resulting in a complex missingness issue. To tackle these issues, we introduce an innovative approach named Vertical Federated Expectation Maximization (VFEM), designed for federated learning under a missing data scenario. We embed a new EM algorithm into VFEM to address complex missing patterns when full dataset access is unfeasible. Furthermore, we establish the linear convergence rate for the VFEM and establish a statistical inference framework, enabling covariates to influence assessment and enhancing model interpretability. Extensive simulation studies are conducted to validate its finite sample performance. Finally, we thoroughly investigate a real-life profit prediction problem for SMEs using VFEM. Our findings demonstrate that VFEM provides a promising solution for addressing data isolation and missing values, ultimately improving the understanding of SMEs' financial performance.

stat.ME

Data Privatization in Vertical Federated Learning with Client-wise Missing Problem

Vertical Federated Learning (VFL) often suffers from client-wise missingness, where entire feature blocks from some clients are unobserved, and conventional approaches are vulnerable to privacy leakage. We propose a Gaussian copulabased framework for VFL data privatization under missingness constraints, which requires no prior specification of downstream analysis tasks and imposes no restriction on the number of analyses. To privately estimate copula parameters, we introduce a debiased randomized response mechanism for correlation matrix estimation from perturbed ranks, together with a nonparametric privatized marginal estimation that yields consistent CDFs even under MAR. The proposed methods comprise VCDS for MCAR data, EVCDS for MAR data, and IEVCDS, which iteratively refines copula parameters to mitigate MAR-induced bias. Notably, EVCDS and IEVCDS also apply under MCAR, and the framework accommodates mixed data types, including discrete variables. Theoretically, we introduce the notion of Vertical Distributed Attribute Differential Privacy (VDADP), tailored to the VFL setting, establish corresponding privacy and utility guarantees, and investigate the utility of privatized data for GLM coefficient estimation and variable selection. We further establish asymptotic properties including estimation and variable selection consistency for VFL-GLMs. Extensive simulations and a real-data application demonstrate the effectiveness of the proposed framework.

stat.ME

PrAda-GAN: A Private Adaptive Generative Adversarial Network with Bayes Network Structure

We revisit the problem of generating synthetic data under differential privacy. To address the core limitations of marginal-based methods, we propose the Private Adaptive Generative Adversarial Network with Bayes Network Structure (PrAda-GAN), which integrates the strengths of both GAN-based and marginal-based approaches. Our method adopts a sequential generator architecture to capture complex dependencies among variables, while adaptively regularizing the learned structure to promote sparsity in the underlying Bayes network. Theoretically, we establish diminishing bounds on the parameter distance, variable selection error, and Wasserstein distance. Our analysis shows that leveraging dependency sparsity leads to significant improvements in convergence rates. Empirically, experiments on both synthetic and real-world datasets demonstrate that PrAda-GAN outperforms existing tabular data synthesis methods in terms of the privacy-utility trade-off.

stat.ML

Doubly Smoothed Density Estimation with Application on Miners' Unsafe Act Detection

We study anomaly detection in images under a fixed-camera environment and propose a \emph{doubly smoothed} (DS) density estimator that exploits spatial structure to improve estimation accuracy. The DS estimator applies kernel smoothing twice: first over the value domain to obtain location-wise classical nonparametric density (CD) estimates, and then over the spatial domain to borrow information from neighboring locations. Under appropriate regularity conditions, we show that the DS estimator achieves smaller asymptotic bias, variance, and mean squared error than the CD estimator. To address the increased computational cost of the DS estimator, we introduce a grid point approximation (GPA) technique that reduces the computation cost of inference without sacrificing the estimation accuracy. A rule-of-thumb bandwidth is derived for practical use. Extensive simulations show that GPA-DS achieves the lowest MSE with near real-time speed. In a large-scale case study on underground mine surveillance, GPA-DS enables remarkable sub-image extraction of anomalous regions after which a lightweight MobileNet classifier achieves $\approx$99\% out-of-sample accuracy for unsafe act detection.

stat.AP

A BERT-based Hierarchical Classification Model with Applications in Chinese Commodity Classification

Existing e-commerce platforms heavily rely on manual annotation for product categorization, which is inefficient and inconsistent. These platforms often employ a hierarchical structure for categorizing products; however, few studies have leveraged this hierarchical information for classification. Furthermore, studies that consider hierarchical information fail to account for similarities and differences across various hierarchical categories. Herein, we introduce a large-scale hierarchical dataset collected from the JD e-commerce platform (www.JD.com), comprising 1,011,450 products with titles and a three-level category structure. By making this dataset openly accessible, we provide a valuable resource for researchers and practitioners to advance research and applications associated with product categorization. Moreover, we propose a novel hierarchical text classification approach based on the widely used Bidirectional Encoder Representations from Transformers (BERT), called Hierarchical Fine-tuning BERT (HFT-BERT). HFT-BERT leverages the remarkable text feature extraction capabilities of BERT, achieving prediction performance comparable to those of existing methods on short texts. Notably, our HFT-BERT model demonstrates exceptional performance in categorizing longer short texts, such as books.

cs.CL

FedVLMBench: Benchmarking Federated Fine-Tuning of Vision-Language Models

Vision-Language Models (VLMs) have demonstrated remarkable capabilities in cross-modal understanding and generation by integrating visual and textual information. While instruction tuning and parameter-efficient fine-tuning methods have substantially improved the generalization of VLMs, most existing approaches rely on centralized training, posing challenges for deployment in domains with strict privacy requirements like healthcare. Recent efforts have introduced Federated Learning (FL) into VLM fine-tuning to address these privacy concerns, yet comprehensive benchmarks for evaluating federated fine-tuning strategies, model architectures, and task generalization remain lacking. In this work, we present \textbf{FedVLMBench}, the first systematic benchmark for federated fine-tuning of VLMs. FedVLMBench integrates two mainstream VLM architectures (encoder-based and encoder-free), four fine-tuning strategies, five FL algorithms, six multimodal datasets spanning four cross-domain single-task scenarios and two cross-domain multitask settings, covering four distinct downstream task categories. Through extensive experiments, we uncover key insights into the interplay between VLM architectures, fine-tuning strategies, data heterogeneity, and multi-task federated optimization. Notably, we find that a 2-layer multilayer perceptron (MLP) connector with concurrent connector and LLM tuning emerges as the optimal configuration for encoder-based VLMs in FL. Furthermore, current FL methods exhibit significantly higher sensitivity to data heterogeneity in vision-centric tasks than text-centric ones, across both encoder-free and encoder-based VLM architectures. Our benchmark provides essential tools, datasets, and empirical guidance for the research community, offering a standardized platform to advance privacy-preserving, federated training of multimodal foundation models.

cs.LG

Selective Aggregation for Low-Rank Adaptation in Federated Learning

We investigate LoRA in federated learning through the lens of the asymmetry analysis of the learned $A$ and $B$ matrices. In doing so, we uncover that $A$ matrices are responsible for learning general knowledge, while $B$ matrices focus on capturing client-specific knowledge. Based on this finding, we introduce Federated Share-A Low-Rank Adaptation (FedSA-LoRA), which employs two low-rank trainable matrices $A$ and $B$ to model the weight update, but only $A$ matrices are shared with the server for aggregation. Moreover, we delve into the relationship between the learned $A$ and $B$ matrices in other LoRA variants, such as rsLoRA and VeRA, revealing a consistent pattern. Consequently, we extend our FedSA-LoRA method to these LoRA variants, resulting in FedSA-rsLoRA and FedSA-VeRA. In this way, we establish a general paradigm for integrating LoRA with FL, offering guidance for future work on subsequent LoRA variants combined with FL. Extensive experimental results on natural language understanding and generation tasks demonstrate the effectiveness of the proposed method. Our code is available at https://github.com/Pengxin-Guo/FedSA-LoRA.

cs.LG