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Feng Luan

Publications and source records attributed to Feng Luan.

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mmcmcBayes:An R Package Implementing a Multistage MCMC Framework for Detecting the Differentially Methylated Regions

Identifying differentially methylated regions is an important task in epigenome-wide association studies, where differential signals often arise across groups of neighboring CpG sites. Many existing methods detect differentially methylated regions by aggregating CpG-level test results, which may limit their ability to capture complex regional methylation patterns. In this paper, we introduce the R package mmcmcBayes, which implements a multistage Markov chain Monte Carlo procedure for region-level detection of differentially methylated regions. The method models sample-wise regional methylation summaries using the alpha-skew generalized normal distribution and evaluates evidence for differential methylation between groups through Bayes factors. We use a multistage region-splitting strategy to refine candidate regions based on statistical evidence. We describe the underlying methodology and software implementation, and illustrate its performance through simulation studies and applications to Illumina 450K methylation data. The mmcmcBayes package provides a practical region-level alternative to existing CpG-based differentially methylated regions detection methods and includes supporting functions for summarizing, comparing, and visualizing detected regions.

stat.AP

A Tactile-based Interactive Motion Planner for Robots in Unknown Cluttered Environments

In unknown cluttered environments with densely stacked objects, the free-motion space is extremely barren, posing significant challenges to motion planners. Collision-free planning methods often suffer from catastrophic failures due to unexpected collisions and motion obstructions. To address this issue, this paper proposes an interactive motion planning framework (I-MP), based on a perception-motion loop. This framework empowers robots to autonomously model and reason about contact models, which in turn enables safe expansion of the free-motion space. Specifically, the robot utilizes multimodal tactile perception to acquire stimulus-response signal pairs. This enables real-time identification of objects' mechanical properties and the subsequent construction of contact models. These models are integrated as computational constraints into a reactive planner. Based on fixed-point theorems, the planner computes the spatial state toward the target in real time, thus avoiding the computational burden associated with extrapolating on high-dimensional interaction models. Furthermore, high-dimensional interaction features are linearly superposed in Cartesian space in the form of energy, and the controller achieves trajectory tracking by solving the energy gradient from the current state to the planned state. The experimental results showed that at cruising speeds ranging from 0.01 to 0.07 $m/s$, the robot's initial contact force with objects remained stable at 1.0 +- 0.7 N. In the cabinet scenario test where collision-free trajectories were unavailable, I-MP expanded the free motion space by 37.5 % through active interaction, successfully completing the environmental exploration task.

cs.RO

Learning Efficient Robotic Garment Manipulation with Standardization

Garment manipulation is a significant challenge for robots due to the complex dynamics and potential self-occlusion of garments. Most existing methods of efficient garment unfolding overlook the crucial role of standardization of flattened garments, which could significantly simplify downstream tasks like folding, ironing, and packing. This paper presents APS-Net, a novel approach to garment manipulation that combines unfolding and standardization in a unified framework. APS-Net employs a dual-arm, multi-primitive policy with dynamic fling to quickly unfold crumpled garments and pick-and-place (p and p) for precise alignment. The purpose of garment standardization during unfolding involves not only maximizing surface coverage but also aligning the garment's shape and orientation to predefined requirements. To guide effective robot learning, we introduce a novel factorized reward function for standardization, which incorporates garment coverage (Cov), keypoint distance (KD), and intersection-over-union (IoU) metrics. Additionally, we introduce a spatial action mask and an Action Optimized Module to improve unfolding efficiency by selecting actions and operation points effectively. In simulation, APS-Net outperforms state-of-the-art methods for long sleeves, achieving 3.9 percent better coverage, 5.2 percent higher IoU, and a 0.14 decrease in KD (7.09 percent relative reduction). Real-world folding tasks further demonstrate that standardization simplifies the folding process. Project page: see https://hellohaia.github.io/APS/

cs.RO

SSFold: Learning to Fold Arbitrary Crumpled Cloth Using Graph Dynamics from Human Demonstration

Robotic cloth manipulation faces challenges due to the fabric's complex dynamics and the high dimensionality of configuration spaces. Previous methods have largely focused on isolated smoothing or folding tasks and overly reliant on simulations, often failing to bridge the significant sim-to-real gap in deformable object manipulation. To overcome these challenges, we propose a two-stream architecture with sequential and spatial pathways, unifying smoothing and folding tasks into a single adaptable policy model that accommodates various cloth types and states. The sequential stream determines the pick and place positions for the cloth, while the spatial stream, using a connectivity dynamics model, constructs a visibility graph from partial point cloud data of the self-occluded cloth, allowing the robot to infer the cloth's full configuration from incomplete observations. To bridge the sim-to-real gap, we utilize a hand tracking detection algorithm to gather and integrate human demonstration data into our novel end-to-end neural network, improving real-world adaptability. Our method, validated on a UR5 robot across four distinct cloth folding tasks with different goal shapes, consistently achieves folded states from arbitrary crumpled initial configurations, with success rates of 99\%, 99\%, 83\%, and 67\%. It outperforms existing state-of-the-art cloth manipulation techniques and demonstrates strong generalization to unseen cloth with diverse colors, shapes, and stiffness in real-world experiments.Videos and source code are available at: https://zcswdt.github.io/SSFold/

cs.RO