arXiv subjects

Fernando Galve

Publications and source records attributed to Fernando Galve.

At least 19 recordsLinked to original sources

arXiv2026

High-resolution ultra-low-field MRI with SNRAware denoising

Ultra-low-field (ULF, <0.1 T) magnetic resonance imaging (MRI) systems offer advantages in cost, portability, and accessibility, but their current utility is still limited by low signal-to-noise ratio (SNR). Deep learning (DL)-based denoising has emerged as a potential strategy to mitigate this limitation. In this work, we present a systematic evaluation of a high-performance DL denoising model trained using the SNRAware framework and applied to 88 mT and 72 mT data. Using a series of controlled experiments, we assessed model performance as a function of spatial resolution, coil impedance matching, readout bandwidth, input noise level, k-space undersampling, anatomy, image contrast, and scanner platform, and compared against analytical denoising algorithms. The model consistently increased the effective SNR of ULF acquisitions, enabling images with nominal spatial resolutions comparable to those commonly used in clinical 3 T protocols. Residual analyses indicated that the model predominantly removed stochastic noise while preserving underlying signal structure. At the same time, the results highlight some constraints: denoising performance remains dependent on the starting SNR of the acquisition, and training-domain mismatch influences behavior under certain artifact conditions. These findings suggest that DL-based denoising can significantly expand the practical capabilities of ULF MRI, while emphasizing potential benefits from hardware-software co-optimization and the need for rigorous clinical validation to determine the diagnostic value of denoised images.

physics.med-ph↗

arXiv2025

Qualitative and quantitative hard-tissue MRI with portable Halbach scanners

Purpose: To demonstrate the feasibility of performing in-vivo imaging and quantitative relaxation mapping of soft and hard tissues using a low-cost, portable MRI scanner, and to establish the methodological foundations for zero echo time (ZTE) imaging in systems affected by strong field inhomogeneities. Methods: A complete framework for artifact-free ZTE imaging at low field was developed, including: (i) RF pulse pre/counteremphasis calibration to minimize ring-down and electronics switching time; (ii) an extension of a recent single-point double-shot (SPDS) protocol for simultaneous B0 and B1 mapping; and (iii) a model-based reconstruction incorporating these field maps into the encoding matrix. ZTE imaging and variable flip angle (VFA) T1 mapping were performed on phantoms and in-vivo human knees and ankles, and benchmarked against standard RARE and STIR acquisitions. Results: The optimized PETRA sequence produced 3D images of knees and ankles within clinically compatible times (< 15 min), revealing hard tissues such as ligaments, tendons, cartilage, and bone that are invisible in spin-echo sequences. The extended SPDS method enabled accurate field mapping, while the VFA approach provided the first in-vivo T1 measurements of hard tissues at B0 < 0.1 T. Conclusions: The proposed framework broadens the range of pulse sequences feasible in portable low-field MRI and demonstrates the potential of ZTE for quantitative and structural imaging of musculoskeletal tissues in affordable Halbach-based systems.

physics.med-ph↗

arXiv2025

Physics-Informed Deep Unrolled Network for Portable MR Image Reconstruction

Magnetic resonance imaging (MRI) is the gold standard imaging modality for numerous diagnostic tasks, yet its usefulness is tempered due to its high cost and infrastructural requirements. Low-cost very-low-field portable scanners offer new opportunities, while enabling imaging outside conventional MRI suites. However, achieving diagnostic-quality images in clinically acceptable scan times remains challenging with these systems. Therefore methods for improving the image quality while reducing the scan duration are highly desirable. Here, we investigate a physics-informed 3D deep unrolled network for the reconstruction of portable MR acquisitions. Our approach includes a novel network architecture that utilizes momentum-based acceleration and leverages complex conjugate symmetry of k-space for improved reconstruction performance. Comprehensive evaluations on emulated datasets as well as 47mT portable MRI acquisitions demonstrate the improved reconstruction quality of the proposed method compared to existing methods.

physics.med-ph↗

arXiv2025

An imageless magnetic resonance framework for fast and cost-effective decision-making

Magnetic Resonance Imaging (MRI) is the gold standard in countless diagnostic procedures, yet hardware complexity, long scans, and cost preclude rapid screening and point-of-care use. We introduce Imageless Magnetic Resonance Diagnosis (IMRD), a framework that bypasses k-space sampling and image reconstruction by analyzing raw one-dimensional MR signals. We identify potentially impactful embodiments where IMRD requires only optimized pulse sequences for time-domain contrast, minimal low-field hardware, and pattern recognition algorithms to answer clinical closed queries and quantify lesion burden. As a proof of concept, we simulate multiple sclerosis lesions in silico within brain phantoms and deploy two extremely fast protocols (approximately 3 s), with and without spatial information. A 1D convolutional neural network achieves AUC close to 0.95 for lesion detection and R2 close to 0.99 for volume estimation. We also perform robustness tests under reduced signal-to-noise ratio, partial signal omission, and relaxation-time variability. By reframing MR signals as direct diagnostic metrics, IMRD paves the way for fast, low-cost MR screening and monitoring in resource-limited environments.

physics.med-ph↗

arXiv2024

Zero-echo-time sequences in highly inhomogeneous fields

Zero echo time (ZTE) sequences have proven a powerful tool for Magnetic Resonance Imaging (MRI) of ultrashort T2 tissues, but they fail to produce useful images in the presence of strong field inhomogeneities. Here we present a method to correct artifacts induced by strong B0 inhomogeneities in non-Cartesian sequences, based on magnetic field maps obtained from the phase difference between two fast pointwise acquisitions. These are free of geometric distortions and can be used for model based image reconstruction with iterative algebraic techniques. In this paper, we show that distortions and artifacts coming from inhomogeneites in B0 are largely reverted by our method, as opposed to standard Conjugate Phase reconstructions. We base this technique on a Single-Point Double-Shot (SPDS) approach, and we have shown it to work even for intra-voxel bandwidths (determined by B0 inhomogeneities) comparable to the encoding bandwidth (determined by the gradient fields). We benchmark the performance of SPDS for ZTE acquisitions, which can be exploited for e.g. dental imaging in affordable low-field MRI systems. Furthermore, SPDS can be used for arbitrary pulse sequences and it may prove useful for extreme magnet geometries, as in e.g. single-sided MRI.

physics.med-ph↗

arXiv2024

Elliptical Halbach magnet and gradient modules for low-field portable MRI

Objective. To develop methods to design the complete magnetic system for a truly portable MRI scanner for neurological and musculoskeletal (MSK) applications, optimized for field homogeneity, field of view (FoV) and gradient performance compared to existing low-weight configurations. Approach. We explore optimal elliptic-bore Halbach configurations based on discrete arrays of permanent magnets. In this way, we seek to improve the field homogeneity and remove constraints to the extent of the gradient coils typical of Halbach magnets. Specifically, we have optimized a tightly-packed distribution of magnetic Nd$_2$Fe$_14$B cubes with differential evolution algorithms, and a second array of shimming magnets with interior point and differential evolution methods. We have also designed and constructed an elliptical set of gradient coils that extend over the whole magnet length, maximizing the distance between the lobe centers. These are optimized with a target field method minimizing a cost function that considers also heat dissipation. Main result. We have employed the new toolbox to build the main magnet and gradient modules for a portable MRI scanner designed for point-of-care and residential use. The elliptical Halbach bore has semi-axes of 10 & 14 cm and the magnet generates a field of 87 mT homogeneous down to 5,700 ppm (parts per million) in a 20 cm diameter FoV, it weighs 216 kg and has a width of 65 cm and a height of 72 cm. Gradient efficiencies go up to around 0.8 mT/m/A, for a maximum of 12 mT/m with in 0.5 ms with 15 A & 15 V amplifier. The distance between lobes is 28 cm, significantly increased with respect to other Halbach-based scanners. Heat dissipation is around 25 W at maximum power, and gradient deviations from linearity are below 20% in a 20 cm sphere.

physics.med-ph↗

arXiv2019

Quantum synchronization in dimer atomic lattices

Synchronization phenomena have been recently reported in the quantum realm at atomic level due to collective dissipation. In this work we propose a dimer lattice of trapped atoms realizing a dissipative spin model where quantum synchronization occurs instead in presence of local dissipation. Atoms synchronization is enabled by the inhomogeneity of staggered local losses in the lattice and is favored by an increase of spins detuning. A comprehensive approach to quantum synchronization based on different measures considered in the literature allows to identify the main features of different synchronization regimes.

quant-ph↗

arXiv2018

Reconfigurable optical implementation of quantum complex networks

Network theory has played a dominant role in understanding the structure of complex systems and their dynamics. Recently, quantum complex networks, i.e. collections of quantum systems in a non-regular topology, have been explored leading to significant progress in a multitude of diverse contexts including, e.g., quantum transport, open quantum systems, quantum communication, extreme violation of local realism, and quantum gravity geometries. However, the question on how to produce and control general quantum complex networks in experimental laboratory has remained open. Here we propose an all optical and reconfigurable implementation of quantum complex networks. The experimental proposal is based on optical frequency combs, parametric processes, pulse shaping and multimode measurements allowing the arbitrary control of the number of the nodes (optical modes) and topology of the links (interactions between the modes) within the network. Moreover, we also show how to simulate quantum dynamics within the network combined with the ability to address its individual nodes. To demonstrate the versatility of these features, we discuss the implementation of two recently proposed probing techniques for quantum complex networks and structured environments. Overall, our general method for implementing quantum complex networks with reconfigurable set-up has potential to define an experimental playground for designing and controlling complex networks -- and dynamics therein -- for several quantum physical frameworks.

quant-ph↗

arXiv2018

Quantum correlations and synchronization measures

The phenomenon of spontaneous synchronization is universal and only recently advances have been made in the quantum domain. Being synchronization a kind of temporal correlation among systems, it is interesting to understand its connection with other measures of quantum correlations. We review here what is known in the field, putting emphasis on measures and indicators of synchronization which have been proposed in the literature, and comparing their validity for different dynamical systems, highlighting when they give similar insights and when they seem to fail.

quant-ph↗

arXiv2017

Dynamical and quantum effects of collective dissipation in optomechanical systems

Optomechanical devices have been cooled to ground-state and genuine quantum features, as well as long-predicted nonlinear phenomena, have been observed. When packing close enough more than one optomechanical unit in the same substrate the question arises as to whether collective or independent dissipation channels are the correct description of the system. Here we explore the effects arising when introducing dissipative couplings between mechanical degrees of freedom. We investigate synchronization, entanglement and cooling, finding that collective dissipation can drive synchronization even in the absence of mechanical direct coupling, and allow to attain larger entanglement and optomechanical cooling. The mechanisms responsible for these enhancements are explored and provide a full and consistent picture.

quant-ph↗

arXiv2016

Probing the spectral density of a dissipative qubit via quantum synchronization

The interaction of a quantum system, which is not accessible by direct measurement, with an external probe can be exploited to infer specific features of the system itself. We introduce a probing scheme based on the emergence of spontaneous quantum synchronization between an out-of-equilibrium qubit, in contact with an external environment, and a probe qubit. Tuning the frequency of the probe leads to a transition between synchronization in phase and antiphase. The sharp transition between these two regimes is locally accessible by monitoring the probe dynamics alone and allows one to reconstruct the shape of the spectral density of the environment.

quant-ph↗

arXiv2016

Minimal model for spontaneous quantum synchronization

We show the emergence of spontaneous synchronization between a pair of detuned quantum oscillators within a harmonic network. Our model does not involve any nonlinearity, driving, or external dissipation, thus providing the simplest scenario for the occurrence of local coherent dynamics in an extended harmonic system. A sufficient condition for synchronization is established by building upon the Rayleigh normal mode approach to vibrational systems. Our results show that mechanisms favoring synchronization, even between oscillators that are not directly coupled to each other, are transient energy depletion and crosstalk. We also address the possible buildup of quantum correlations during synchronization and show that indeed entanglement may be generated in detuned systems, starting from uncorrelated states and without any direct coupling between the two oscillators.

quant-ph↗

arXiv2016

Microscopic description for the emergence of collective dissipation in extended quantum systems

Practical implementations of quantum technology are limited by unavoidable effects of decoherence and dissipation. With achieved experimental control for individual atoms and photons, more complex platforms composed by several units can be assembled enabling distinctive forms of dissipation and decoherence, in independent heat baths or collectively into a common bath, with dramatic consequences for the preservation of quantum coherence. The cross-over between these two regimes has been widely attributed in the literature to the system units being farther apart than the bath's correlation length. Starting from a microscopic model of a structured environment (a crystal) sensed by two bosonic probes, here we show the failure of such conceptual relation, and identify the exact physical mechanism underlying this cross-over, displaying a sharp contrast between dephasing and dissipative baths. Depending on the frequency of the system and, crucially, on its orientation with respect to the crystal axes, collective dissipation becomes possible for very large distances between probes, opening new avenues to deal with decoherence in phononic baths.

quant-ph↗

arXiv2016

Complex quantum networks as structured environments: engineering and probing

We consider structured environments modeled by bosonic quantum networks and investigate the probing of their spectral density, structure, and topology. We demonstrate how to engineer a desired spectral density by changing the network structure. Our results show that the spectral density can be very accurately detected via a locally immersed quantum probe for virtually any network configuration. Moreover, we show how the entire network structure can be reconstructed by using a single quantum probe. We illustrate our findings presenting examples of spectral densities and topology probing for networks of genuine complexity.

quant-ph↗

arXiv2016

Entropy production and thermodynamic power of the squeezed thermal reservoir

We analyze the entropy production and the maximal extractable work from a squeezed thermal reservoir. The nonequilibrium quantum nature of the reservoir induces an entropy transfer with a coherent contribution while modifying its thermal part, allowing work extraction from a single reservoir, as well as great improvements in power and efficiency for quantum heat engines. Introducing a modified quantum Otto cycle, our approach fully characterizes operational regimes forbidden in the standard case, such as refrigeration and work extraction at the same time, accompanied by efficiencies equal to unity.

quant-ph↗

arXiv2015

Quantum Darwinism and non-Markovian dissipative dynamics from quantum phases of the spin-1/2 XX model

Quantum Darwinism explains the emergence of a classical description of objects in terms of the creation of many redundant registers in an environment containing their classical information. This amplification phenomenon, where only classical information reaches the macroscopic observer and through which different observers can agree on the objective existence of such object, has been revived lately for several types of situations, successfully explaining classicality. We explore quantum Darwinism in the setting of an environment made of two level systems which are initially prepared in the ground state of the XX model, which exhibits different phases; we find that the different phases have different ability to redundantly acquire classical information about the system, being the "ferromagnetic phase" the only one able to complete quantum Darwinism. At the same time we relate this ability to how non-Markovian the system dynamics is, based on the interpretation that non-Markovian dynamics is associated to back flow of information from environment to system, thus spoiling the information transfer needed for Darwinism. Finally, we explore mixing of bath registers by allowing a small interaction among them, finding that this spoils the stored information as previously found in the literature.

quant-ph↗

arXiv2014

Energy and information propagation in a finite coupled bosonic heat bath

The finite coupled bosonic model of reservoir introduced by Vasile et al. [1] to characterize non-Markovianity, is used to study the different dissipative behaviors of a harmonic oscillator coupled to it when it is in resonance, close to resonance or far detuned. We show that information and energy exchange between system and heat bath go hand in hand because phonons are the carriers of both: in resonance free propagation of excitations is achieved, and therefore pure dissipation, while when far detuned the system can only correlate with the first oscillator in the bath's chain, leading to almost unitary evolution. In the intermediate situation we show the penetration of correlations and the formation of oscillatory (dressed state) behavior, which lies at the root of non-Markovianity.

quant-ph↗

arXiv2013

Entangling power of two-qubit gates on mixed states

The ability to reach a maximally entangled state from a separable one through the use of a two-qubit unitary operator is analyzed for mixed states. This extension from the known case of pure states shows that there are at least two families of gates which are able to give maximum entangling power for all values of purity. It is notable that one of this gates coincides with a maximum discording one. We give analytical proof that such gate is indeed perfect entangler at all purities and give numerical evidence for the existence of the second one. Further, we find that there are other gates, many in fact, which are perfect entanglers for a restricted range of purities. This highlights the fact that many perfect entangler gates could in principle be found if a thorough analysis of the full parameter space is performed.

quant-ph↗