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Frances T. Sheehan

Publications and source records attributed to Frances T. Sheehan.

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Automated ACL Footprint Identification Using 3D Deep Learning

One of the most common reasons for anterior cruciate ligament (ACL) reconstruction failure is femoral tunnel malpositioning (ACL footprint center and tunnel orientation). Such failures may lead to the development of meniscal pathology and osteoarthritis. Accurate ACL femoral footprint identification is therefore essential for precise tunnel placement, restoration of the native knee joint mechanics, post-surgical knee joint health and prevention of graft failure. Recent advances in artificial intelligence (AI) bring new opportunities to improve image-guided orthopedic surgery. However, at present, existing AI research focuses primarily on ACL segmentation and rupture classification based on pre- and post-operative magnetic resonance (MR) images. Identification of the ACL footprint center using deep learning methods has not been thoroughly researched. Thus, the purpose of this study is to explore 3D deep learning models for ACL femoral footprint identification directly from 3D MR images. Two comprehensive 3D deep learning architectures were developed: a 3D graph convolutional neural network-based geometric model applied to 3D femoral meshes; and a 3D landmark-enhanced identification model based on 3D MR images. A total of 4883 right and 3087 left knee image sets were used from a publicly available database. Eighty percent (80%) were applied to model generation, and twenty percent (20%) were preserved for model testing. Both models achieved excellent performance; however, the image-based method outperformed the model-based method (average error of 2.1mm vs 2.8 mm). Thus, 3D deep learning provides a feasible clinical approach for ACL footprint localization and has the potential to improve ACL reconstruction footprint accuracy.

cs.CV

Healthy versus pathological learning transferability in shoulder muscle MRI segmentation using deep convolutional encoder-decoders

Automatic segmentation of pathological shoulder muscles in patients with musculo-skeletal diseases is a challenging task due to the huge variability in muscle shape, size, location, texture and injury. A reliable fully-automated segmentation method from magnetic resonance images could greatly help clinicians to plan therapeutic interventions and predict interventional outcomes while eliminating time consuming manual segmentation efforts. The purpose of this work is three-fold. First, we investigate the feasibility of pathological shoulder muscle segmentation using deep learning techniques, given a very limited amount of available annotated pediatric data. Second, we address the learning transferability from healthy to pathological data by comparing different learning schemes in terms of model generalizability. Third, extended versions of deep convolutional encoder-decoder architectures using encoders pre-trained on non-medical data are proposed to improve the segmentation accuracy. Methodological aspects are evaluated in a leave-one-out fashion on a dataset of 24 shoulder examinations from patients with obstetrical brachial plexus palsy and focus on 4 different muscles including deltoid as well as infraspinatus, supraspinatus and subscapularis from the rotator cuff. The most relevant segmentation model is partially pre-trained on ImageNet and jointly exploits inter-patient healthy and pathological annotated data. Its performance reaches Dice scores of 82.4%, 82.0%, 71.0% and 82.8% for deltoid, infraspinatus, supraspinatus and subscapularis muscles. Absolute surface estimation errors are all below 83mm$^2$ except for supraspinatus with 134.6mm$^2$. These contributions offer new perspectives for force inference in the context of musculo-skeletal disorder management.

cs.CV