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Francesco Renna

Publications and source records attributed to Francesco Renna.

17 recordsLinked to original sources

Multifractal Recalibration of Neural Networks for Medical Imaging Segmentation

Multifractal analysis has revealed regularities in many self-seeding phenomena, yet its use in modern deep learning remains limited. Existing end-to-end multifractal methods rely on heavy pooling or strong feature-space decimation, which constrain tasks such as semantic segmentation. Motivated by these limitations, we introduce two inductive priors: Monofractal and Multifractal Recalibration. These methods leverage relationships between the probability mass of the exponents and the multifractal spectrum to form statistical descriptions of encoder embeddings, implemented as channel-attention functions in convolutional networks. Using a U-Net-based framework, we show that multifractal recalibration yields substantial gains over a baseline equipped with other channel-attention mechanisms that also use higher-order statistics. Given the proven ability of multifractal analysis to capture pathological regularities, we validate our approach on three public medical-imaging datasets: ISIC18 (dermoscopy), Kvasir-SEG (endoscopy), and BUSI (ultrasound). Our empirical analysis also provides insights into the behavior of these attention layers. We find that excitation responses do not become increasingly specialized with encoder depth in U-Net architectures due to skip connections, and that their effectiveness may relate to global statistics of instance variability.

cs.CV

Instance-wise Uncertainty for Class Imbalance in Semantic Segmentation

Semantic segmentation is a fundamental computer vision task with a vast number of applications. State of the art methods increasingly rely on deep learning models, known to incorrectly estimate uncertainty and being overconfident in predictions, especially in data not seen during training. This is particularly problematic in semantic segmentation due to inherent class imbalance. Popular uncertainty quantification approaches are task-agnostic and fail to leverage spatial pixel correlations in uncertainty estimates, crucial in this task. In this work, a novel training methodology specifically designed for semantic segmentation is presented. Training samples are weighted by instance-wise uncertainty masks computed by an ensemble. This is shown to increase performance on minority classes, boost model generalization and robustness to domain-shift when compared to using the inverse of class proportions or no class weights at all. This method addresses the challenges of class imbalance and uncertainty estimation in semantic segmentation, potentially enhancing model performance and reliability across various applications.

cs.CV

Beyond Heart Murmur Detection: Automatic Murmur Grading from Phonocardiogram

Objective: Murmurs are abnormal heart sounds, identified by experts through cardiac auscultation. The murmur grade, a quantitative measure of the murmur intensity, is strongly correlated with the patient's clinical condition. This work aims to estimate each patient's murmur grade (i.e., absent, soft, loud) from multiple auscultation location phonocardiograms (PCGs) of a large population of pediatric patients from a low-resource rural area. Methods: The Mel spectrogram representation of each PCG recording is given to an ensemble of 15 convolutional residual neural networks with channel-wise attention mechanisms to classify each PCG recording. The final murmur grade for each patient is derived based on the proposed decision rule and considering all estimated labels for available recordings. The proposed method is cross-validated on a dataset consisting of 3456 PCG recordings from 1007 patients using a stratified ten-fold cross-validation. Additionally, the method was tested on a hidden test set comprised of 1538 PCG recordings from 442 patients. Results: The overall cross-validation performances for patient-level murmur gradings are 86.3% and 81.6% in terms of the unweighted average of sensitivities and F1-scores, respectively. The sensitivities (and F1-scores) for absent, soft, and loud murmurs are 90.7% (93.6%), 75.8% (66.8%), and 92.3% (84.2%), respectively. On the test set, the algorithm achieves an unweighted average of sensitivities of 80.4% and an F1-score of 75.8%. Conclusions: This study provides a potential approach for algorithmic pre-screening in low-resource settings with relatively high expert screening costs. Significance: The proposed method represents a significant step beyond detection of murmurs, providing characterization of intensity which may provide a enhanced classification of clinical outcomes.

q-bio.QM

The CirCor DigiScope Dataset: From Murmur Detection to Murmur Classification

Cardiac auscultation is one of the most cost-effective techniques used to detect and identify many heart conditions. Computer-assisted decision systems based on auscultation can support physicians in their decisions. Unfortunately, the application of such systems in clinical trials is still minimal since most of them only aim to detect the presence of extra or abnormal waves in the phonocardiogram signal, i.e., only a binary ground truth variable (normal vs abnormal) is provided. This is mainly due to the lack of large publicly available datasets, where a more detailed description of such abnormal waves (e.g., cardiac murmurs) exists. To pave the way to more effective research on healthcare recommendation systems based on auscultation, our team has prepared the currently largest pediatric heart sound dataset. A total of 5282 recordings have been collected from the four main auscultation locations of 1568 patients, in the process, 215780 heart sounds have been manually annotated. Furthermore, and for the first time, each cardiac murmur has been manually annotated by an expert annotator according to its timing, shape, pitch, grading, and quality. In addition, the auscultation locations where the murmur is present were identified as well as the auscultation location where the murmur is detected more intensively. Such detailed description for a relatively large number of heart sounds may pave the way for new machine learning algorithms with a real-world application for the detection and analysis of murmur waves for diagnostic purposes.

q-bio.QM

On instabilities of deep learning in image reconstruction - Does AI come at a cost?

Deep learning, due to its unprecedented success in tasks such as image classification, has emerged as a new tool in image reconstruction with potential to change the field. In this paper we demonstrate a crucial phenomenon: deep learning typically yields unstablemethods for image reconstruction. The instabilities usually occur in several forms: (1) tiny, almost undetectable perturbations, both in the image and sampling domain, may result in severe artefacts in the reconstruction, (2) a small structural change, for example a tumour, may not be captured in the reconstructed image and (3) (a counterintuitive type of instability) more samples may yield poorer performance. Our new stability test with algorithms and easy to use software detects the instability phenomena. The test is aimed at researchers to test their networks for instabilities and for government agencies, such as the Food and Drug Administration (FDA), to secure safe use of deep learning methods.

cs.CV

Reconstruction of optical vector-fields with applications in endoscopic imaging

We introduce a framework for the reconstruction of the amplitude, phase and polarisation of an optical vector-field using calibration measurements acquired by an imaging device with an unknown linear transformation. By incorporating effective regularisation terms, this new approach is able to recover an optical vector-field with respect to an arbitrary representation system, which may be different from the one used in calibration. In particular, it enables the recovery of an optical vector-field with respect to a Fourier basis, which is shown to yield indicative features of increased scattering associated with tissue abnormalities. We demonstrate the effectiveness of our approach using synthetic holographic images as well as biological tissue samples in an experimental setting where measurements of an optical vector-field are acquired by a fibre endoscope, and observe that indeed the recovered Fourier coefficients are useful in distinguishing healthy tissues from lesions in early stages of oesophageal cancer.

math.NA

Media Query Processing For The Internet-of-Things: Coupling Of Device Energy Consumption And Cloud Infrastructure Billing

Audio/visual recognition and retrieval applications have recently garnered significant attention within Internet-of-Things (IoT) oriented services, given that video cameras and audio processing chipsets are now ubiquitous even in low-end embedded systems. In the most typical scenario for such services, each device extracts audio/visual features and compacts them into feature descriptors, which comprise media queries. These queries are uploaded to a remote cloud computing service that performs content matching for classification or retrieval applications. Two of the most crucial aspects for such services are: (i) controlling the device energy consumption when using the service; (ii) reducing the billing cost incurred from the cloud infrastructure provider. In this paper we derive analytic conditions for the optimal coupling between the device energy consumption and the incurred cloud infrastructure billing. Our framework encapsulates: the energy consumption to produce and transmit audio/visual queries, the billing rates of the cloud infrastructure, the number of devices concurrently connected to the same cloud server, {the query volume constraint of each cluster of devices,} and the statistics of the query data production volume per device. Our analytic results are validated via a deployment with: (i) the device side comprising compact image descriptors (queries) computed on Beaglebone Linux embedded platforms and transmitted to Amazon Web Services (AWS) Simple Storage Service; (ii) the cloud side carrying out image similarity detection via AWS Elastic Compute Cloud (EC2) instances, with the AWS Auto Scaling being used to control the number of instances according to the demand.

cs.MM

Bounds on the Number of Measurements for Reliable Compressive Classification

This paper studies the classification of high-dimensional Gaussian signals from low-dimensional noisy, linear measurements. In particular, it provides upper bounds (sufficient conditions) on the number of measurements required to drive the probability of misclassification to zero in the low-noise regime, both for random measurements and designed ones. Such bounds reveal two important operational regimes that are a function of the characteristics of the source: i) when the number of classes is less than or equal to the dimension of the space spanned by signals in each class, reliable classification is possible in the low-noise regime by using a one-vs-all measurement design; ii) when the dimension of the spaces spanned by signals in each class is lower than the number of classes, reliable classification is guaranteed in the low-noise regime by using a simple random measurement design. Simulation results both with synthetic and real data show that our analysis is sharp, in the sense that it is able to gauge the number of measurements required to drive the misclassification probability to zero in the low-noise regime.

cs.IT

Classification and Reconstruction of High-Dimensional Signals from Low-Dimensional Features in the Presence of Side Information

This paper offers a characterization of fundamental limits on the classification and reconstruction of high-dimensional signals from low-dimensional features, in the presence of side information. We consider a scenario where a decoder has access both to linear features of the signal of interest and to linear features of the side information signal; while the side information may be in a compressed form, the objective is recovery or classification of the primary signal, not the side information. The signal of interest and the side information are each assumed to have (distinct) latent discrete labels; conditioned on these two labels, the signal of interest and side information are drawn from a multivariate Gaussian distribution. With joint probabilities on the latent labels, the overall signal-(side information) representation is defined by a Gaussian mixture model. We then provide sharp sufficient and/or necessary conditions for these quantities to approach zero when the covariance matrices of the Gaussians are nearly low-rank. These conditions, which are reminiscent of the well-known Slepian-Wolf and Wyner-Ziv conditions, are a function of the number of linear features extracted from the signal of interest, the number of linear features extracted from the side information signal, and the geometry of these signals and their interplay. Moreover, on assuming that the signal of interest and the side information obey such an approximately low-rank model, we derive expansions of the reconstruction error as a function of the deviation from an exactly low-rank model; such expansions also allow identification of operational regimes where the impact of side information on signal reconstruction is most relevant. Our framework, which offers a principled mechanism to integrate side information in high-dimensional data problems, is also tested in the context of imaging applications.

cs.IT

Mismatch in the Classification of Linear Subspaces: Sufficient Conditions for Reliable Classification

This paper considers the classification of linear subspaces with mismatched classifiers. In particular, we assume a model where one observes signals in the presence of isotropic Gaussian noise and the distribution of the signals conditioned on a given class is Gaussian with a zero mean and a low-rank covariance matrix. We also assume that the classifier knows only a mismatched version of the parameters of input distribution in lieu of the true parameters. By constructing an asymptotic low-noise expansion of an upper bound to the error probability of such a mismatched classifier, we provide sufficient conditions for reliable classification in the low-noise regime that are able to sharply predict the absence of a classification error floor. Such conditions are a function of the geometry of the true signal distribution, the geometry of the mismatched signal distributions as well as the interplay between such geometries, namely, the principal angles and the overlap between the true and the mismatched signal subspaces. Numerical results demonstrate that our conditions for reliable classification can sharply predict the behavior of a mismatched classifier both with synthetic data and in a motion segmentation and a hand-written digit classification applications.

cs.IT

Query Processing For The Internet-of-Things: Coupling Of Device Energy Consumption And Cloud Infrastructure Billing

Audio/visual recognition and retrieval applications have recently garnered significant attention within Internet-of-Things (IoT) oriented services, given that video cameras and audio processing chipsets are now ubiquitous even in low-end embedded systems. In the most typical scenario for such services, each device extracts audio/visual features and compacts them into feature descriptors, which comprise media queries. These queries are uploaded to a remote cloud computing service that performs content matching for classification or retrieval applications. Two of the most crucial aspects for such services are: (i) controlling the device energy consumption when using the service; (ii) reducing the billing cost incurred from the cloud infrastructure provider. In this paper we derive analytic conditions for the optimal coupling between the device energy consumption and the incurred cloud infrastructure billing. Our framework encapsulates: the energy consumption to produce and transmit audio/visual queries, the billing rates of the cloud infrastructure, the number of devices concurrently connected to the same cloud server, and the statistics of the query data production volume per device. Our analytic results are validated via a deployment with: (i) the device side comprising compact image descriptors (queries) computed on Beaglebone Linux embedded platforms and transmitted to Amazon Web Services (AWS) Simple Storage Service; (ii) the cloud side carrying out image similarity detection via AWS Elastic Compute Cloud (EC2) spot instances, with the AWS Auto Scaling being used to control the number of instances according to the demand.

cs.NI

Secrecy Transmission on Block Fading Channels: Theoretical Limits and Performance of Practical Codes

We consider a system where an agent (Alice) aims at transmitting a message to a second agent (Bob) over a set of parallel channels, while keeping it secret from a third agent (Eve) by using physical layer security techniques. We assume that Alice perfectly knows the set of channels with respect to Bob, but she has only a statistical knowledge of the channels with respect to Eve. We derive bounds on the achievable outage secrecy rates, by considering coding either within each channel or across all parallel channels. Transmit power is adapted to the channel conditions, with a constraint on the average power over the whole transmission. We also focus on the maximum cumulative outage secrecy rate that can be achieved. Moreover, in order to assess the performance in a real life scenario, we consider the use of practical error correcting codes. We extend the definitions of security gap and equivocation rate, previously applied to the single additive white Gaussian noise channel, to Rayleigh distributed parallel channels, on the basis of the error rate targets and the outage probability. Bounds on these metrics are also derived, taking into account the statistics of the parallel channels. Numerical results are provided, that confirm the feasibility of the considered physical layer security techniques.

cs.IT

Achievable Secrecy Rates over MIMOME Gaussian Channels with GMM Signals in Low-Noise Regime

We consider a wiretap multiple-input multiple-output multiple-eavesdropper (MIMOME) channel, where agent Alice aims at transmitting a secret message to agent Bob, while leaking no information on it to an eavesdropper agent Eve. We assume that Alice has more antennas than both Bob and Eve, and that she has only statistical knowledge of the channel towards Eve. We focus on the low-noise regime, and assess the secrecy rates that are achievable when the secret message determines the distribution of a multivariate Gaussian mixture model (GMM) from which a realization is generated and transmitted over the channel. In particular, we show that if Eve has fewer antennas than Bob, secret transmission is always possible at low-noise. Moreover, we show that in the low-noise limit the secrecy capacity of our scheme coincides with its unconstrained capacity, by providing a class of covariance matrices that allow to attain such limit without the need of wiretap coding.

cs.IT

Reconstruction of Signals Drawn from a Gaussian Mixture from Noisy Compressive Measurements

This paper determines to within a single measurement the minimum number of measurements required to successfully reconstruct a signal drawn from a Gaussian mixture model in the low-noise regime. The method is to develop upper and lower bounds that are a function of the maximum dimension of the linear subspaces spanned by the Gaussian mixture components. The method not only reveals the existence or absence of a minimum mean-squared error (MMSE) error floor (phase transition) but also provides insight into the MMSE decay via multivariate generalizations of the MMSE dimension and the MMSE power offset, which are a function of the interaction between the geometrical properties of the kernel and the Gaussian mixture. These results apply not only to standard linear random Gaussian measurements but also to linear kernels that minimize the MMSE. It is shown that optimal kernels do not change the number of measurements associated with the MMSE phase transition, rather they affect the sensed power required to achieve a target MMSE in the low-noise regime. Overall, our bounds are tighter and sharper than standard bounds on the minimum number of measurements needed to recover sparse signals associated with a union of subspaces model, as they are not asymptotic in the signal dimension or signal sparsity.

cs.IT

Compressive Classification of a Mixture of Gaussians: Analysis, Designs and Geometrical Interpretation

This paper derives fundamental limits on the performance of compressive classification when the source is a mixture of Gaussians. It provides an asymptotic analysis of a Bhattacharya based upper bound on the misclassification probability for the optimal Maximum-A-Posteriori (MAP) classifier that depends on quantities that are dual to the concepts of diversity-order and coding gain in multi-antenna communications. The diversity-order of the measurement system determines the rate at which the probability of misclassification decays with signal-to-noise ratio (SNR) in the low-noise regime. The counterpart of coding gain is the measurement gain which determines the power offset of the probability of misclassification in the low-noise regime. These two quantities make it possible to quantify differences in misclassification probability between random measurement and (diversity-order) optimized measurement. Results are presented for two-class classification problems first with zero-mean Gaussians then with nonzero-mean Gaussians, and finally for multiple-class Gaussian classification problems. The behavior of misclassification probability is revealed to be intimately related to certain fundamental geometric quantities determined by the measurement system, the source and their interplay. Numerical results, representative of compressive classification of a mixture of Gaussians, demonstrate alignment of the actual misclassification probability with the Bhattacharya based upper bound. The connection between the misclassification performance and the alignment between source and measurement geometry may be used to guide the design of dictionaries for compressive classification.

cs.IT

Compressive Classification

This paper derives fundamental limits associated with compressive classification of Gaussian mixture source models. In particular, we offer an asymptotic characterization of the behavior of the (upper bound to the) misclassification probability associated with the optimal Maximum-A-Posteriori (MAP) classifier that depends on quantities that are dual to the concepts of diversity gain and coding gain in multi-antenna communications. The diversity, which is shown to determine the rate at which the probability of misclassification decays in the low noise regime, is shown to depend on the geometry of the source, the geometry of the measurement system and their interplay. The measurement gain, which represents the counterpart of the coding gain, is also shown to depend on geometrical quantities. It is argued that the diversity order and the measurement gain also offer an optimization criterion to perform dictionary learning for compressive classification applications.

cs.IT

Low-power Secret-key Agreement over OFDM

Information-theoretic secret-key agreement is perhaps the most practically feasible mechanism that provides unconditional security at the physical layer to date. In this paper, we consider the problem of secret-key agreement by sharing randomness at low power over an orthogonal frequency division multiplexing (OFDM) link, in the presence of an eavesdropper. The low power assumption greatly simplifies the design of the randomness sharing scheme, even in a fading channel scenario. We assess the performance of the proposed system in terms of secrecy key rate and show that a practical approach to key sharing is obtained by using low-density parity check (LDPC) codes for information reconciliation. Numerical results confirm the merits of the proposed approach as a feasible and practical solution. Moreover, the outage formulation allows to implement secret-key agreement even when only statistical knowledge of the eavesdropper channel is available.

cs.IT