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Franz Rothlauf

Publications and source records attributed to Franz Rothlauf.

At least 19 recordsLinked to original sources

An Imbalanced Dataset with Multiple Feature Representations for Studying Quality Control of Next-Generation Sequencing

Next-generation sequencing (NGS) is a key technique for studying the DNA and RNA of organisms. However, identifying quality problems in NGS data across different experimental settings remains challenging. To develop automated quality-control tools, researchers require datasets with features that capture the characteristics of quality problems. Existing NGS repositories, however, offer only a limited number of quality-related features. To address this gap, we propose a dataset derived from 37,491 NGS samples with two types of quality-related feature representations. The first type consists of 34 features derived from quality control tools (QC-34 features). The second type has a variable number of features ranging from eight to 1,183. These features were derived from read counts in problematic genomic regions identified by the ENCODE blocklist (BL features). All features describe the same human and mouse samples from five genomic assays, allowing direct comparison of feature representations. The proposed dataset includes a binary quality label, derived from automated quality control and domain experts. Among all samples, $3.2\%$ are of low quality. Supervised machine learning algorithms accurately predicted quality labels from the features, confirming the relevance of the provided feature representations. The proposed feature representations enable researchers to study how different feature types (QC-34 vs. BL features) and granularities (varying number of BL features) affect the detection of quality problems.

q-bio.GN

ROIDS: Robust Outlier-Aware Informed Down-Sampling

Informed down-sampling (IDS) is known to improve performance in symbolic regression when combined with various selection strategies, especially tournament selection. However, recent work found that IDS's gains are not consistent across all problems. Our analysis reveals that IDS performance is worse for problems containing outliers. IDS systematically favors including outliers in subsets which pushes GP towards finding solutions that overfit to outliers. To address this, we introduce ROIDS (Robust Outlier-Aware Informed Down-Sampling), which excludes potential outliers from the sampling process of IDS. With ROIDS it is possible to keep the advantages of IDS without overfitting to outliers and to compete on a wide range of benchmark problems. This is also reflected in our experiments in which ROIDS shows the desired behavior on all studied benchmark problems. ROIDS consistently outperforms IDS on synthetic problems with added outliers as well as on a wide range of complex real-world problems, surpassing IDS on over 80% of the real-world benchmark problems. Moreover, compared to all studied baseline approaches, ROIDS achieves the best average rank across all tested benchmark problems. This robust behavior makes ROIDS a reliable down-sampling method for selection in symbolic regression, especially when outliers may be included in the data set.

cs.NE

Transformer Semantic Genetic Programming for d-dimensional Symbolic Regression Problems

Transformer Semantic Genetic Programming (TSGP) is a semantic search approach that uses a pre-trained transformer model as a variation operator to generate offspring programs with high semantic similarity to a given parent. Unlike other semantic GP approaches that rely on fixed syntactic transformations, TSGP aims to learn diverse structural variations that lead to solutions with similar semantics. We find that a single transformer model trained on millions of programs is able to generalize across symbolic regression problems of varying dimension. Evaluated on 24 real-world and synthetic datasets, TSGP significantly outperforms standard GP, SLIM_GSGP, Deep Symbolic Regression, and Denoising Autoencoder GP, achieving an average rank of 1.58 across all benchmarks. Moreover, TSGP produces more compact solutions than SLIM_GSGP, despite its higher accuracy. In addition, the target semantic distance is able to effectively adjust the step size in the semantic space: small values enable consistent improvement in fitness but often lead to larger programs, while larger values promote faster convergence and compactness. Thus, the target semantic distance provides an effective mechanism for balancing exploration and exploitation.

cs.LG

We Need to Rethink Benchmarking in Anomaly Detection

Despite the continuous proposal of new anomaly detection algorithms and extensive benchmarking efforts, progress seems to stagnate, with only minor performance differences between established baselines and new algorithms. In this position paper, we argue that this stagnation is due to limitations in how we evaluate anomaly detection algorithms. In current benchmarks, a trivial algorithm that only checks for extreme values in individual features performs competitively with state-of-the-art deep learning methods, despite failing on simple cases such as anomalies within an annulus of normal points. Moreover, existing benchmarks do not adequately reflect the diversity of anomaly detection applications, making it difficult for practitioners to reliably select algorithms for their applications. Consequently, we need to rethink benchmarking in anomaly detection. In our opinion, anomaly detection should be studied using scenarios that group applications sharing relevant characteristics, defined through a common taxonomy. Benchmarking within scenarios enables scenario-specific choices for preprocessing, metrics, and model selection, clarifying which advances transfer across similar applications and providing practitioners with reliable guidance for their specific contexts.

cs.LG

A Performance Analysis of Lexicase-Based and Traditional Selection Methods in GP for Symbolic Regression

In recent years, several new lexicase-based selection variants have emerged due to the success of standard lexicase selection in various application domains. For symbolic regression problems, variants that use an epsilon-threshold or batches of training cases, among others, have led to performance improvements. Lately, especially variants that combine lexicase selection and down-sampling strategies have received a lot of attention. This paper evaluates the most relevant lexicase-based selection methods as well as traditional selection methods in combination with different down-sampling strategies on a wide range of symbolic regression problems. In contrast to most work, we not only compare the methods over a given evaluation budget, but also over a given time budget as time is usually limited in practice. We find that for a given evaluation budget, epsilon-lexicase selection in combination with a down-sampling strategy outperforms all other methods. If the given running time is very short, lexicase variants using batches of training cases perform best. Further, we find that the combination of tournament selection with informed down-sampling performs well in all studied settings.

cs.NE

Was Tournament Selection All We Ever Needed? A Critical Reflection on Lexicase Selection

The success of lexicase selection has led to various extensions, including its combination with down-sampling, which further increased performance. However, recent work found that down-sampling also leads to significant improvements in the performance of tournament selection. This raises the question of whether tournament selection combined with down-sampling is the better choice, given its faster running times. To address this question, we run a set of experiments comparing epsilon-lexicase and tournament selection with different down-sampling techniques on synthetic problems of varying noise levels and problem sizes as well as real-world symbolic regression problems. Overall, we find that down-sampling improves generalization and performance even when compared over the same number of generations. This means that down-sampling is beneficial even with way fewer fitness evaluations. Additionally, down-sampling successfully reduces code growth. We observe that population diversity increases for tournament selection when combined with down-sampling. Further, we find that tournament selection and epsilon-lexicase selection with down-sampling perform similar, while tournament selection is significantly faster. We conclude that tournament selection should be further analyzed and improved in future work instead of only focusing on the improvement of lexicase variants.

cs.NE

Transformer Semantic Genetic Programming for Symbolic Regression

In standard genetic programming (stdGP), solutions are varied by modifying their syntax, with uncertain effects on their semantics. Geometric-semantic genetic programming (GSGP), a popular variant of GP, effectively searches the semantic solution space using variation operations based on linear combinations, although it results in significantly larger solutions. This paper presents Transformer Semantic Genetic Programming (TSGP), a novel and flexible semantic approach that uses a generative transformer model as search operator. The transformer is trained on synthetic test problems and learns semantic similarities between solutions. Once the model is trained, it can be used to create offspring solutions with high semantic similarity also for unseen and unknown problems. Experiments on several symbolic regression problems show that TSGP generates solutions with comparable or even significantly better prediction quality than stdGP, SLIM_GSGP, DSR, and DAE-GP. Like SLIM_GSGP, TSGP is able to create new solutions that are semantically similar without creating solutions of large size. An analysis of the search dynamic reveals that the solutions generated by TSGP are semantically more similar than the solutions generated by the benchmark approaches allowing a better exploration of the semantic solution space.

cs.NE

ComfyGI: Automatic Improvement of Image Generation Workflows

Automatic image generation is no longer just of interest to researchers, but also to practitioners. However, current models are sensitive to the settings used and automatic optimization methods often require human involvement. To bridge this gap, we introduce ComfyGI, a novel approach to automatically improve workflows for image generation without the need for human intervention driven by techniques from genetic improvement. This enables image generation with significantly higher quality in terms of the alignment with the given description and the perceived aesthetics. On the performance side, we find that overall, the images generated with an optimized workflow are about 50% better compared to the initial workflow in terms of the median ImageReward score. These already good results are even surpassed in our human evaluation, as the participants preferred the images improved by ComfyGI in around 90% of the cases.

cs.CV

Robust Statistical Scaling of Outlier Scores: Improving the Quality of Outlier Probabilities for Outliers (Extended Version)

Outlier detection algorithms typically assign an outlier score to each observation in a dataset, indicating the degree to which an observation is an outlier. However, these scores are often not comparable across algorithms and can be difficult for humans to interpret. Statistical scaling addresses this problem by transforming outlier scores into outlier probabilities without using ground-truth labels, thereby improving interpretability and comparability across algorithms. However, the quality of this transformation can be different for outliers and inliers. Missing outliers in scenarios where they are of particular interest - such as healthcare, finance, or engineering - can be costly or dangerous. Thus, ensuring good probabilities for outliers is essential. This paper argues that statistical scaling, as commonly used in the literature, does not produce equally good probabilities for outliers as for inliers. Therefore, we propose robust statistical scaling, which uses robust estimators to improve the probabilities for outliers. We evaluate several variants of our method against other outlier score transformations for real-world datasets and outlier detection algorithms, where it can improve the probabilities for outliers.

cs.LG

Large Language Models Suffer From Their Own Output: An Analysis of the Self-Consuming Training Loop

Large Language Models (LLM) are already widely used to generate content for a variety of online platforms. As we are not able to safely distinguish LLM-generated content from human-produced content, LLM-generated content is used to train the next generation of LLMs, giving rise to a self-consuming training loop. From the image generation domain we know that such a self-consuming training loop reduces both quality and diversity of images finally ending in a model collapse. However, it is unclear whether this alarming effect can also be observed for LLMs. Therefore, we present the first study investigating the self-consuming training loop for LLMs. Further, we propose a novel method based on logic expressions that allows us to unambiguously verify the correctness of LLM-generated content, which is difficult for natural language text. We find that the self-consuming training loop produces correct outputs, however, the output declines in its diversity depending on the proportion of the used generated data. Fresh data can slow down this decline, but not stop it. Given these concerning results, we encourage researchers to study methods to negate this process.

cs.LG

Informed Down-Sampled Lexicase Selection: Identifying productive training cases for efficient problem solving

Genetic Programming (GP) often uses large training sets and requires all individuals to be evaluated on all training cases during selection. Random down-sampled lexicase selection evaluates individuals on only a random subset of the training cases allowing for more individuals to be explored with the same amount of program executions. However, creating a down-sample randomly might exclude important cases from the current down-sample for a number of generations, while cases that measure the same behavior (synonymous cases) may be overused despite their redundancy. In this work, we introduce Informed Down-Sampled Lexicase Selection. This method leverages population statistics to build down-samples that contain more distinct and therefore informative training cases. Through an empirical investigation across two different GP systems (PushGP and Grammar-Guided GP), we find that informed down-sampling significantly outperforms random down-sampling on a set of contemporary program synthesis benchmark problems. Through an analysis of the created down-samples, we find that important training cases are included in the down-sample consistently across independent evolutionary runs and systems. We hypothesize that this improvement can be attributed to the ability of Informed Down-Sampled Lexicase Selection to maintain more specialist individuals over the course of evolution, while also benefiting from reduced per-evaluation costs.

cs.NE

Do You Trust ChatGPT? -- Perceived Credibility of Human and AI-Generated Content

This paper examines how individuals perceive the credibility of content originating from human authors versus content generated by large language models, like the GPT language model family that powers ChatGPT, in different user interface versions. Surprisingly, our results demonstrate that regardless of the user interface presentation, participants tend to attribute similar levels of credibility. While participants also do not report any different perceptions of competence and trustworthiness between human and AI-generated content, they rate AI-generated content as being clearer and more engaging. The findings from this study serve as a call for a more discerning approach to evaluating information sources, encouraging users to exercise caution and critical thinking when engaging with content generated by AI systems.

cs.HC

Down-Sampled Epsilon-Lexicase Selection for Real-World Symbolic Regression Problems

Epsilon-lexicase selection is a parent selection method in genetic programming that has been successfully applied to symbolic regression problems. Recently, the combination of random subsampling with lexicase selection significantly improved performance in other genetic programming domains such as program synthesis. However, the influence of subsampling on the solution quality of real-world symbolic regression problems has not yet been studied. In this paper, we propose down-sampled epsilon-lexicase selection which combines epsilon-lexicase selection with random subsampling to improve the performance in the domain of symbolic regression. Therefore, we compare down-sampled epsilon-lexicase with traditional selection methods on common real-world symbolic regression problems and analyze its influence on the properties of the population over a genetic programming run. We find that the diversity is reduced by using down-sampled epsilon-lexicase selection compared to standard epsilon-lexicase selection. This comes along with high hyperselection rates we observe for down-sampled epsilon-lexicase selection. Further, we find that down-sampled epsilon-lexicase selection outperforms the traditional selection methods on all studied problems. Overall, with down-sampled epsilon-lexicase selection we observe an improvement of the solution quality of up to 85% in comparison to standard epsilon-lexicase selection.

cs.NE

MTGP: Combining Metamorphic Testing and Genetic Programming

Genetic programming is an evolutionary approach known for its performance in program synthesis. However, it is not yet mature enough for a practical use in real-world software development, since usually many training cases are required to generate programs that generalize to unseen test cases. As in practice, the training cases have to be expensively hand-labeled by the user, we need an approach to check the program behavior with a lower number of training cases. Metamorphic testing needs no labeled input/output examples. Instead, the program is executed multiple times, first on a given (randomly generated) input, followed by related inputs to check whether certain user-defined relations between the observed outputs hold. In this work, we suggest MTGP, which combines metamorphic testing and genetic programming and study its performance and the generalizability of the generated programs. Further, we analyze how the generalizability depends on the number of given labeled training cases. We find that using metamorphic testing combined with labeled training cases leads to a higher generalization rate than the use of labeled training cases alone in almost all studied configurations. Consequently, we recommend researchers to use metamorphic testing in their systems if the labeling of the training data is expensive.

cs.SE

The Randomness of Input Data Spaces is an A Priori Predictor for Generalization

Over-parameterized models can perfectly learn various types of data distributions, however, generalization error is usually lower for real data in comparison to artificial data. This suggests that the properties of data distributions have an impact on generalization capability. This work focuses on the search space defined by the input data and assumes that the correlation between labels of neighboring input values influences generalization. If correlation is low, the randomness of the input data space is high leading to high generalization error. We suggest to measure the randomness of an input data space using Maurer's universal. Results for synthetic classification tasks and common image classification benchmarks (MNIST, CIFAR10, and Microsoft's cats vs. dogs data set) find a high correlation between the randomness of input data spaces and the generalization error of deep neural networks for binary classification problems.

cs.LG

Choose Your Programming Copilot: A Comparison of the Program Synthesis Performance of GitHub Copilot and Genetic Programming

GitHub Copilot, an extension for the Visual Studio Code development environment powered by the large-scale language model Codex, makes automatic program synthesis available for software developers. This model has been extensively studied in the field of deep learning, however, a comparison to genetic programming, which is also known for its performance in automatic program synthesis, has not yet been carried out. In this paper, we evaluate GitHub Copilot on standard program synthesis benchmark problems and compare the achieved results with those from the genetic programming literature. In addition, we discuss the performance of both approaches. We find that the performance of the two approaches on the benchmark problems is quite similar, however, in comparison to GitHub Copilot, the program synthesis approaches based on genetic programming are not yet mature enough to support programmers in practical software development. Genetic programming usually needs a huge amount of expensive hand-labeled training cases and takes too much time to generate solutions. Furthermore, source code generated by genetic programming approaches is often bloated and difficult to understand. For future work on program synthesis with genetic programming, we suggest researchers to focus on improving the execution time, readability, and usability.

cs.SE

Recent Developments in Program Synthesis with Evolutionary Algorithms

The automatic generation of computer programs is one of the main applications with practical relevance in the field of evolutionary computation. With program synthesis techniques not only software developers could be supported in their everyday work but even users without any programming knowledge could be empowered to automate repetitive tasks and implement their own new functionality. In recent years, many novel program synthesis approaches based on evolutionary algorithms have been proposed and evaluated on common benchmark problems. Therefore, we identify in this work the relevant evolutionary program synthesis approaches and provide an in-depth analysis of their performance. The most influential approaches we identify are stack-based, grammar-guided, as well as linear genetic programming. Further, we find that these approaches perform well on benchmark problems if there is a simple mapping from the given input to the correct output. On problems where this mapping is complex, e.g., if the problem consists of several sub-problems or requires iteration/recursion for a correct solution, results tend to be worse. Consequently, for future work, we encourage researchers not only to use a program's output for assessing the quality of a solution but also the way towards a solution (e.g., correctly solved sub-problems).

cs.NE

Deep Boltzmann Machines in Estimation of Distribution Algorithms for Combinatorial Optimization

Estimation of Distribution Algorithms (EDAs) require flexible probability models that can be efficiently learned and sampled. Deep Boltzmann Machines (DBMs) are generative neural networks with these desired properties. We integrate a DBM into an EDA and evaluate the performance of this system in solving combinatorial optimization problems with a single objective. We compare the results to the Bayesian Optimization Algorithm. The performance of DBM-EDA was superior to BOA for difficult additively decomposable functions, i.e., concatenated deceptive traps of higher order. For most other benchmark problems, DBM-EDA cannot clearly outperform BOA, or other neural network-based EDAs. In particular, it often yields optimal solutions for a subset of the runs (with fewer evaluations than BOA), but is unable to provide reliable convergence to the global optimum competitively. At the same time, the model building process is computationally more expensive than that of other EDAs using probabilistic models from the neural network family, such as DAE-EDA.

cs.NE