SearcharxivSearch

arXiv subjects

Franz Wegner

Publications and source records attributed to Franz Wegner.

13 recordsLinked to original sources

Characterization of the Clinically Approved MRI Tracer Resotran for Magnetic Particle Imaging in a Comparison Study

Objective. The availability of magnetic nanoparticles with medical approval for human intervention is fundamental to the clinical translation of magnetic particle imaging (MPI). In this work, we thoroughly evaluate and compare the magnetic properties of an magnetic resonance imaging (MRI) approved tracer to validate its performance for MPI in future human trials. Approach. We analyze whether the recently approved MRI tracer Resotran is suitable for MPI. In addition, we compare Resotran with the previously approved and extensively studied tracer Resovist, with Ferrotran, which is currently in a clinical phase III study, and with the tailored MPI tracer Perimag. Main results. Initial magnetic particle spectroscopy measurements indicate that Resotran exhibits performance characteristics akin to Resovist, but below Perimag. We provide data on four different tracers using dynamic light scattering, transmission electron microscopy, vibrating sample magnetometry measurements, magnetic particle spectroscopy to derive hysteresis, point spread functions, and a serial dilution, as well as system matrix based MPI measurements on a preclinical scanner (Bruker 25/20 FF), including reconstructed images. Significance. Numerous approved magnetic nanoparticles used as tracers in MRI lack the necessary magnetic properties essential for robust signal generation in MPI. The process of obtaining medical approval for dedicated MPI tracers optimized for signal performance is an arduous and costly endeavor, often only justifiable for companies with a well-defined clinical business case. Resotran is an approved tracer that has become available in Europe for MRI. In this work, we study the eligibility of Resotran for MPI in an effort to pave the way for human MPI trials.

physics.med-ph

The Collatz Problem generalized to 3x+k

The Collatz problem with $3x+k$ is revisited. Positive and negative limit cycles are given up to k=9997 starting with $x_0=-2\cdot10^7...+2\cdot10^7$. A simple relation between the probability distribution for the Syracuse iterates for various k (not divisible by 2 and 3) is obtained. From this it follows that the oscillation considered by Tao 2019 ( arXiv:1909.03562v2 ) does not depend on k. Thus this piece of the proof of his theorem 1.3 "Almost all Collatz orbits attain almost bounded values" holds for all k not divisible by 2 and 3.

math.DS

From Elastica to Floating Bodies of Equilibrium

A short historical account of the curves related to the two-dimensional floating bodies of equilibrium and the bicycle problem is given. Bor, Levi, Perline and Tabachnikov found, quite a number had already been described as Elastica by Bernoulli and Euler and as Elastica under Pressure or Buckled Rings by Levy and Halphen. Auerbach already realized that Zindler had described curves for the floating bodies problem. An even larger class of curves solves the bicycle problem. The subsequent sections deal with some supplemental details: Several derivations of the equations for the elastica and elastica under pressure are given. Properties of Zindler curves and some work on the problem of floating bodies of equilibrium by other mathematicians are considered. Special cases of elastica under pressure reduce to algebraic curves, as shown by Greenhill. Since most of the curves considered here are bicycle curves, a few remarks concerning them are added.

physics.class-ph

Floating Bodies of Equilibrium in Three Dimensions. The central symmetric case

Three-dimensional central symmetric bodies different from spheres that can float in all orientations are considered. For relative density rho=1/2 there are solutions, if holes in the body are allowed. For rho different from 1/2 the body is deformed from a sphere. A set of nonlinear shape-equations determines the shape in lowest order in the deformation. It is shown that a large number of solutions exists. An expansion scheme is given, which allows a formal expansion in the deformation to arbitrary order under the assumption that apart from x=0,+1,-1 there is no x, which obeys P_{p,2}(x)=0 for two different integer ps, where P are Legendre functions.

physics.class-ph

Floating Bodies of Equilibrium at Density 1/2 in Arbitrary Dimensions

Bodies of density one half (of the fluid in which they are immersed) that can float in all orientations are investigated. It is shown that expansions starting from and deforming the (hyper)sphere are possible in arbitrary dimensions and allow for a large manifold of solutions: One may either (i) expand r(n)+r(-n) in powers of a given difference r(u)-r(-u), (r(n) denoting the distance from the origin in direction n). Or (ii) the envelope of the water planes (for fixed body and varying direction of gravitation) may be given. Equivalently r(n) can be expanded in powers of the distance h(u) of the water planes from the origin perpendicular to u.

physics.class-ph

Rigid unit modes in tetrahedral crystals

The 'rigid unit mode' (RUM) model requires unit blocks, in our case tetrahedra of SiO_4 groups, to be rigid within first order of the displacements of the O-ions. The wave-vectors of the lattice vibrations, which obey this rigidity, are determined analytically. Lattices with inversion symmetry yield generically surfaces of RUMs in reciprocal space, whereas lattices without this symmetry yield generically lines of RUMs. Only in exceptional cases as in beta-quartz a surface of RUMs appears, if inversion symmetry is lacking. The occurence of planes and bending surfaces, straight and bent lines is discussed. Explicit calculations are performed for five modifications of SiO_2 crystals.

cond-mat.mtrl-sci

Floating Bodies of Equilibrium. Explicit Solution

Explicit solutions of the two-dimensional floating body problem (bodies that can float in all positions) for relative density rho different from 1/2 and of the tire track problem (tire tracks of a bicycle, which do not allow to determine, which way the bicycle went) are given, which differ from circles. Starting point is the differential equation given in archive physics/0205059 and Studies in Appl. Math. 111 (2003) 167-183.

physics.class-ph

Flow Equations and Normal Ordering. A Survey

First we give an introduction to the method of diagonalizing or block-diagonalizing continuously a Hamiltonian and explain how this procedure can be used to analyze the two-dimensional Hubbard model. Then we give a short survey on applications of this flow equation on other models. Finally we outline, how symmetry breaking can be introduced by means of a symmetry breaking of the normal ordering, not of the Hamiltonian.

cond-mat.stat-mech

Flow Equations and Normal Ordering

In this paper we consider flow-equations where we allow a normal ordering which is adjusted to the one-particle energy of the Hamiltonian. We show that this flow converges nearly always to the stable phase. Starting out from the symmetric Hamiltonian and symmetry-broken normal ordering nearly always yields symmetry breaking below the critical temperature.

cond-mat.stat-mech

Floating Bodies of Equilibrium I

A long cylindrical body of circular cross-section and homogeneous density may float in all orientations around the cylinder axis. It is shown that there are also bodies of non-circular cross-sections which may float in any direction. Apart from those found by Auerbach for rho=1/2 there are one-parameter families of cross-sections for rho not= 1/2 which have a p-fold rotation axis. For given p they exist for p-2 densities rho. There are strong indications, that for all p-2 densities one has the same family of cross-sections. (Proven in physics/0205059)

physics.class-ph

Floating Bodies of Equilibrium II

In a previous paper (physics/0203061) ''Floating bodies of equilibrium I'' I have shown that there exist two-dimensional non-circular cross-sections of bodies of homogeneous densities rho not equal 1/2 which can float in any orientation in water, which have a p-fold rotation axis. For given p they exist for p-2 different densities. However, this was found only in a Taylor-expansion in a parameter which describes the distortion from the circular shape up to seventh order. Here a differential equation for the boundary curve is given and the non-circular boundary curve can be expressed in terms of an elliptic integral.

physics.class-ph

Flow Equations for Electron-Phonon Interactions

A recently proposed method of continuous unitary transformations is used to eliminate the interaction between electrons and phonons. The differential equations for the couplings represent an infinitesimal formulation of a sequence of Fröhlich-transformations. The two approaches are compared. Our result will turn out to be less singular than Fröhlich's. Furthermore the interaction between electrons belonging to a Cooper-pair will always be attractive in our approach. Even in the case where Fröhlich's transformation is not defined (Fröhlich actually excluded these regions from the transformation), we obtain an elimination of the electron-phonon interaction. This is due to a sufficiently slow change of the phonon energies as a function of the flow parameter.

cond-mat

The structure of the spectrum of anomalous dimensions in the N-vector model in 4-epsilon dimensions

In a recent publication we have investigated the spectrum of anomalous dimensions for arbitrary composite operators in the critical N-vector model in 4-epsilon dimensions. We could establish properties like upper and lower bounds for the anomalous dimensions in one-loop order. In this paper we extend these results and explicitly derive parts of the one-loop spectrum of anomalous dimensions. This analysis becomes possible by an explicit representation of the conformal symmetry group on the operator algebra. Still the structure of the spectrum of anomalous dimensions is quite complicated and does generally not resemble the algebraic structures familiar from two dimensional conformal field theories.

hep-th