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Gang Ning

Publications and source records attributed to Gang Ning.

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ASTAR: Automated induction of STAndardized radiology Reporting templates from large-scale clinical free-text corpora

Structured reporting converts free-text radiology narratives into queryable data keys, facilitating cohort assembly, longitudinal tracking, and training label generation for medical AI. The prevailing paradigm follows a two-stage pipeline: (1) constructing a reporting template, (2) extracting information to populate it. While the extraction stage has benefited from advances in large language models (LLMs), template construction remains a manual bottleneck relying on labor-intensive expert consensus that is static, difficult to scale, and may fail to capture real-world reporting diversity. We address this limitation with \textbf{\texttt{ASTAR}}, an LLM-based framework for Automated induction of STAndardized radiology Reporting templates from large-scale clinical free-text corpora. Extensive experiments on 4,215 fetal brain MRI reports from multiple centers demonstrate that the \textbf{\texttt{ASTAR}}-induced template surpasses two expert-curated templates across template coverage, information fidelity, diagnostic fidelity, and expert-rated usability, reducing template development from weeks of committee deliberation to hours of automated processing. Code: https://github.com/birthlab/ASTAR

cs.CL

Annotation-free deep learning for detection and segmentation of fetal germinal matrix-intraventricular hemorrhage in brain MRI

Prenatal germinal matrix-intraventricular hemorrhage (GMH-IVH) is a leading cause of infant mortality and neurodevelopmental impairment, yet its manual diagnosis and lesion segmentation on fetal brain MRI are labor-intensive and error-prone. Although supervised deep learning offers potential for automation, it typically requires large amounts of annotated GMH-IVH data, which are challenging to obtain for such a rare condition (0.5-0.9 per 1000 pregnancies). To address these problems, an annotation-free deep learning framework, FreeHemoSeg, was developed for automated detection and segmentation of GMH-IVH without any real patient annotations. Instead of learning from expert labels, FreeHemoSeg was trained on pseudo GMH-IVH images synthesized from normal fetal data guided by medical priors. The framework was evaluated in a retrospective multicentre study of 1,674 stacks of 2D T2-weighted MRI from 558 pregnant women, using data from one hospital for internal training and validation and two hospitals for external validation. FreeHemoSeg achieved the highest diagnostic and segmentation performance in both internal validation (AUROC: 0.959; AUPR: 0.928; sensitivity: 0.914; specificity: 0.966; DSC: 0.559) and external validation (AUROC: 0.930; AUPR: 0.884; sensitivity: 0.824; specificity: 0.943; DSC: 0.512), outperforming a supervised model trained on limited empirical data and unsupervised anomaly detection methods. Moreover, FreeHemoSeg assistance improved radiologists' sensitivity (from 0.882 to 0.941-1.000) and diagnostic confidence, while reducing interpretation time by 16.0-52.7%. We anticipate its immediate utility in supporting earlier diagnosis, prognostic counselling, and perinatal planning for fetal GMH-IVH. Code: https://github.com/Arktis2022/FreeHemoSeg.

eess.IV