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Ge Yang

Publications and source records attributed to Ge Yang.

At least 55 records · Page 3Linked to original sources

Strong Lensing Source Reconstruction Using Continuous Neural Fields

From the nature of dark matter to the rate of expansion of our Universe, observations of distant galaxies distorted through strong gravitational lensing have the potential to answer some of the major open questions in astrophysics. Modeling galaxy-galaxy strong lensing observations presents a number of challenges as the exact configuration of both the background source and foreground lens galaxy is unknown. A timely call, prompted by a number of upcoming surveys anticipating high-resolution lensing images, demands methods that can efficiently model lenses at their full complexity. In this work, we introduce a method that uses continuous neural fields to non-parametrically reconstruct the complex morphology of a source galaxy while simultaneously inferring a distribution over foreground lens galaxy configurations. We demonstrate the efficacy of our method through experiments on simulated data targeting high-resolution lensing images similar to those anticipated in near-future astrophysical surveys.

astro-ph.CO

Elucidating Meta-Structures of Noisy Labels in Semantic Segmentation by Deep Neural Networks

Supervised training of deep neural networks (DNNs) by noisy labels has been studied extensively in image classification but much less in image segmentation. Our understanding of the learning behavior of DNNs trained by noisy segmentation labels remains limited. We address this deficiency in both binary segmentation of biological microscopy images and multi-class segmentation of natural images. We classify segmentation labels according to their noise transition matrices (NTMs) and compare performance of DNNs trained by different types of labels. When we randomly sample a small fraction (e.g., 10%) or flip a large fraction (e.g., 90%) of the ground-truth labels to train DNNs, their segmentation performance remains largely unchanged. This indicates that DNNs learn structures hidden in labels rather than pixel-level labels per se in their supervised training for semantic segmentation. We call these hidden structures meta-structures. When labels with different perturbations to the meta-structures are used to train DNNs, their performance in feature extraction and segmentation degrades consistently. In contrast, addition of meta-structure information substantially improves performance of an unsupervised model in binary semantic segmentation. We formulate meta-structures mathematically as spatial density distributions. We show theoretically and experimentally how this formulation explains key observed learning behavior of DNNs.

cs.CV

Overcoming the Spectral Bias of Neural Value Approximation

Value approximation using deep neural networks is at the heart of off-policy deep reinforcement learning, and is often the primary module that provides learning signals to the rest of the algorithm. While multi-layer perceptron networks are universal function approximators, recent works in neural kernel regression suggest the presence of a spectral bias, where fitting high-frequency components of the value function requires exponentially more gradient update steps than the low-frequency ones. In this work, we re-examine off-policy reinforcement learning through the lens of kernel regression and propose to overcome such bias via a composite neural tangent kernel. With just a single line-change, our approach, the Fourier feature networks (FFN) produce state-of-the-art performance on challenging continuous control domains with only a fraction of the compute. Faster convergence and better off-policy stability also make it possible to remove the target network without suffering catastrophic divergences, which further reduces TD}(0)'s estimation bias on a few tasks.

cs.LG

Semi-Supervised Segmentation of Mitochondria from Electron Microscopy Images Using Spatial Continuity

Morphology of mitochondria plays critical roles in mediating their physiological functions. Accurate segmentation of mitochondria from 3D electron microscopy (EM) images is essential to quantitative characterization of their morphology at the nanometer scale. Fully supervised deep learning models developed for this task achieve excellent performance but require substantial amounts of annotated data for training. However, manual annotation of EM images is laborious and time-consuming because of their large volumes, limited contrast, and low signal-to-noise ratios (SNRs). To overcome this challenge, we propose a semi-supervised deep learning model that segments mitochondria by leveraging the spatial continuity of their structural, morphological, and contextual information in both labeled and unlabeled images. We use random piecewise affine transformation to synthesize comprehensive and realistic mitochondrial morphology for augmentation of training data. Experiments on the EPFL dataset show that our model achieves performance similar as that of state-of-the-art fully supervised models but requires only ~20% of their annotated training data. Our semi-supervised model is versatile and can also accurately segment other spatially continuous structures from EM images. Data and code of this study are openly accessible at https://github.com/cbmi-group/MPP.

cs.CV

Invariance Through Latent Alignment

A robot's deployment environment often involves perceptual changes that differ from what it has experienced during training. Standard practices such as data augmentation attempt to bridge this gap by augmenting source images in an effort to extend the support of the training distribution to better cover what the agent might experience at test time. In many cases, however, it is impossible to know test-time distribution-shift a priori, making these schemes infeasible. In this paper, we introduce a general approach, called Invariance Through Latent Alignment (ILA), that improves the test-time performance of a visuomotor control policy in deployment environments with unknown perceptual variations. ILA performs unsupervised adaptation at deployment-time by matching the distribution of latent features on the target domain to the agent's prior experience, without relying on paired data. Although simple, we show that this idea leads to surprising improvements on a variety of challenging adaptation scenarios, including changes in lighting conditions, the content in the scene, and camera poses. We present results on calibrated control benchmarks in simulation -- the distractor control suite -- and a physical robot under a sim-to-real setup.

cs.LG

Rapid Locomotion via Reinforcement Learning

Agile maneuvers such as sprinting and high-speed turning in the wild are challenging for legged robots. We present an end-to-end learned controller that achieves record agility for the MIT Mini Cheetah, sustaining speeds up to 3.9 m/s. This system runs and turns fast on natural terrains like grass, ice, and gravel and responds robustly to disturbances. Our controller is a neural network trained in simulation via reinforcement learning and transferred to the real world. The two key components are (i) an adaptive curriculum on velocity commands and (ii) an online system identification strategy for sim-to-real transfer leveraged from prior work. Videos of the robot's behaviors are available at: https://agility.csail.mit.edu/

cs.RO

Deep Neural Networks Learn Meta-Structures from Noisy Labels in Semantic Segmentation

How deep neural networks (DNNs) learn from noisy labels has been studied extensively in image classification but much less in image segmentation. So far, our understanding of the learning behavior of DNNs trained by noisy segmentation labels remains limited. In this study, we address this deficiency in both binary segmentation of biological microscopy images and multi-class segmentation of natural images. We generate extremely noisy labels by randomly sampling a small fraction (e.g., 10%) or flipping a large fraction (e.g., 90%) of the ground truth labels. When trained with these noisy labels, DNNs provide largely the same segmentation performance as trained by the original ground truth. This indicates that DNNs learn structures hidden in labels rather than pixel-level labels per se in their supervised training for semantic segmentation. We refer to these hidden structures in labels as meta-structures. When DNNs are trained by labels with different perturbations to the meta-structure, we find consistent degradation in their segmentation performance. In contrast, incorporation of meta-structure information substantially improves performance of an unsupervised segmentation model developed for binary semantic segmentation. We define meta-structures mathematically as spatial density distributions and show both theoretically and experimentally how this formulation explains key observed learning behavior of DNNs.

cs.CV

Single electrons on solid neon as a solid-state qubit platform

Progress toward the realization of quantum computers requires persistent advances in their constituent building blocks - qubits. Novel qubit platforms that simultaneously embody long coherence, fast operation, and large scalability offer compelling advantages in the construction of quantum computers and many other quantum information systems. Electrons, ubiquitous elementary particles of nonzero charge, spin, and mass, have commonly been perceived as paradigmatic local quantum information carriers. Despite superior controllability and configurability, their practical performance as qubits via either motional or spin states depends critically on their material environment. Here we report our experimental realization of a new qubit platform based upon isolated single electrons trapped on an ultraclean solid neon surface in vacuum. By integrating an electron trap in a circuit quantum electrodynamics architecture, we achieve strong coupling between the motional states of a single electron and a single microwave photon in an on-chip superconducting resonator. Qubit gate operations and dispersive readout are implemented to measure the energy relaxation time $T_1$ of $15~μ$s and phase coherence time $T_2$ over $200~$ns. These results indicate that the electron-on-solid-neon qubit already performs near the state of the art as a charge qubit.

quant-ph

World Model as a Graph: Learning Latent Landmarks for Planning

Planning - the ability to analyze the structure of a problem in the large and decompose it into interrelated subproblems - is a hallmark of human intelligence. While deep reinforcement learning (RL) has shown great promise for solving relatively straightforward control tasks, it remains an open problem how to best incorporate planning into existing deep RL paradigms to handle increasingly complex environments. One prominent framework, Model-Based RL, learns a world model and plans using step-by-step virtual rollouts. This type of world model quickly diverges from reality when the planning horizon increases, thus struggling at long-horizon planning. How can we learn world models that endow agents with the ability to do temporally extended reasoning? In this work, we propose to learn graph-structured world models composed of sparse, multi-step transitions. We devise a novel algorithm to learn latent landmarks that are scattered (in terms of reachability) across the goal space as the nodes on the graph. In this same graph, the edges are the reachability estimates distilled from Q-functions. On a variety of high-dimensional continuous control tasks ranging from robotic manipulation to navigation, we demonstrate that our method, named L3P, significantly outperforms prior work, and is oftentimes the only method capable of leveraging both the robustness of model-free RL and generalization of graph-search algorithms. We believe our work is an important step towards scalable planning in reinforcement learning.

cs.AI

Learning Task Informed Abstractions

Current model-based reinforcement learning methods struggle when operating from complex visual scenes due to their inability to prioritize task-relevant features. To mitigate this problem, we propose learning Task Informed Abstractions (TIA) that explicitly separates reward-correlated visual features from distractors. For learning TIA, we introduce the formalism of Task Informed MDP (TiMDP) that is realized by training two models that learn visual features via cooperative reconstruction, but one model is adversarially dissociated from the reward signal. Empirical evaluation shows that TIA leads to significant performance gains over state-of-the-art methods on many visual control tasks where natural and unconstrained visual distractions pose a formidable challenge.

cs.LG

Advancing biological super-resolution microscopy through deep learning: a brief review

Super-resolution microscopy overcomes the diffraction limit of conventional light microscopy in spatial resolution. By providing novel spatial or spatio-temporal information on biological processes at nanometer resolution with molecular specificity, it plays an increasingly important role in life sciences. However, its technical limitations require trade-offs to balance its spatial resolution, temporal resolution, and light exposure of samples. Recently, deep learning has achieved breakthrough performance in many image processing and computer vision tasks. It has also shown great promise in pushing the performance envelope of super-resolution microscopy. In this brief Review, we survey recent advances in using deep learning to enhance performance of super-resolution microscopy. We focus primarily on how deep learning ad-vances reconstruction of super-resolution images. Related key technical challenges are discussed. Despite the challenges, deep learning is set to play an indispensable and transformative role in the development of super-resolution microscopy. We conclude with an outlook on how deep learning could shape the future of this new generation of light microscopy technology.

physics.bio-ph

Few shot domain adaptation for in situ macromolecule structural classification in cryo-electron tomograms

Motivation: Cryo-Electron Tomography (cryo-ET) visualizes structure and spatial organization of macromolecules and their interactions with other subcellular components inside single cells in the close-to-native state at sub-molecular resolution. Such information is critical for the accurate understanding of cellular processes. However, subtomogram classification remains one of the major challenges for the systematic recognition and recovery of the macromolecule structures in cryo-ET because of imaging limits and data quantity. Recently, deep learning has significantly improved the throughput and accuracy of large-scale subtomogram classification. However often it is difficult to get enough high-quality annotated subtomogram data for supervised training due to the enormous expense of labeling. To tackle this problem, it is beneficial to utilize another already annotated dataset to assist the training process. However, due to the discrepancy of image intensity distribution between source domain and target domain, the model trained on subtomograms in source domainmay perform poorly in predicting subtomogram classes in the target domain. Results: In this paper, we adapt a few shot domain adaptation method for deep learning based cross-domain subtomogram classification. The essential idea of our method consists of two parts: 1) take full advantage of the distribution of plentiful unlabeled target domain data, and 2) exploit the correlation between the whole source domain dataset and few labeled target domain data. Experiments conducted on simulated and real datasets show that our method achieves significant improvement on cross domain subtomogram classification compared with baseline methods.

q-bio.QM

Plan2Vec: Unsupervised Representation Learning by Latent Plans

In this paper we introduce plan2vec, an unsupervised representation learning approach that is inspired by reinforcement learning. Plan2vec constructs a weighted graph on an image dataset using near-neighbor distances, and then extrapolates this local metric to a global embedding by distilling path-integral over planned path. When applied to control, plan2vec offers a way to learn goal-conditioned value estimates that are accurate over long horizons that is both compute and sample efficient. We demonstrate the effectiveness of plan2vec on one simulated and two challenging real-world image datasets. Experimental results show that plan2vec successfully amortizes the planning cost, enabling reactive planning that is linear in memory and computation complexity rather than exhaustive over the entire state space.

cs.LG

Probabilistic Inference for Camera Calibration in Light Microscopy under Circular Motion

Robust and accurate camera calibration is essential for 3D reconstruction in light microscopy under circular motion. Conventional methods require either accurate key point matching or precise segmentation of the axial-view images. Both remain challenging because specimens often exhibit transparency/translucency in a light microscope. To address those issues, we propose a probabilistic inference based method for the camera calibration that does not require sophisticated image pre-processing. Based on 3D projective geometry, our method assigns a probability on each of a range of voxels that cover the whole object. The probability indicates the likelihood of a voxel belonging to the object to be reconstructed. Our method maximizes a joint probability that distinguishes the object from the background. Experimental results show that the proposed method can accurately recover camera configurations in both light microscopy and natural scene imaging. Furthermore, the method can be used to produce high-fidelity 3D reconstructions and accurate 3D measurements.

cs.CV

Spectroscopy of Wigner molecules on superfluid helium using a superconducting resonator

Electrons on helium form a unique two-dimensional electron system on the interface of liquid helium and vacuum. On liquid helium, trapped electrons can arrange into strongly correlated states known as Wigner molecules, which can be used to study electron interactions in the absence of disorder, or as a highly promising resource for quantum computation. Wigner molecules have orbital frequencies in the microwave regime and can therefore be integrated with circuit quantum electrodynamics (cQED), which studies light-matter interactions using microwave photons. Here, we experimentally realize a cQED platform with the orbital state of Wigner molecules on helium. We deterministically prepare one to four-electron Wigner molecules on top of a microwave resonator, which allows us to observe their unique spectra for the first time. Furthermore, we find a single-electron-photon coupling strength of g/2$π$ = 4.8$\pm$0.3 MHz, greatly exceeding the resonator linewidth $κ$/2$π$ = 0.5 MHz. These results pave the way towards microwave studies of strongly correlated electron states and coherent control of the orbital and spin state of Wigner molecules on helium.}

cond-mat.mes-hall

Some Considerations on Learning to Explore via Meta-Reinforcement Learning

We consider the problem of exploration in meta reinforcement learning. Two new meta reinforcement learning algorithms are suggested: E-MAML and E-$\text{RL}^2$. Results are presented on a novel environment we call `Krazy World' and a set of maze environments. We show E-MAML and E-$\text{RL}^2$ deliver better performance on tasks where exploration is important.

cs.AI

Learning Plannable Representations with Causal InfoGAN

In recent years, deep generative models have been shown to 'imagine' convincing high-dimensional observations such as images, audio, and even video, learning directly from raw data. In this work, we ask how to imagine goal-directed visual plans -- a plausible sequence of observations that transition a dynamical system from its current configuration to a desired goal state, which can later be used as a reference trajectory for control. We focus on systems with high-dimensional observations, such as images, and propose an approach that naturally combines representation learning and planning. Our framework learns a generative model of sequential observations, where the generative process is induced by a transition in a low-dimensional planning model, and an additional noise. By maximizing the mutual information between the generated observations and the transition in the planning model, we obtain a low-dimensional representation that best explains the causal nature of the data. We structure the planning model to be compatible with efficient planning algorithms, and we propose several such models based on either discrete or continuous states. Finally, to generate a visual plan, we project the current and goal observations onto their respective states in the planning model, plan a trajectory, and then use the generative model to transform the trajectory to a sequence of observations. We demonstrate our method on imagining plausible visual plans of rope manipulation.

cs.LG