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Georges Humbert

Publications and source records attributed to Georges Humbert.

4 recordsLinked to original sources

Targeted Sub-attomole Cancer Biomarker Detection based on Phase Singularity 2D Nanomaterial-enhanced Plasmonic Biosensor

Detection of small cancer biomarkers with low molecular weight and a low concentration range has always been challenging yet urgent in many clinical applications such as diagnosing early-stage cancer, monitoring treatment and detecting relapse. Here, a highly enhanced plasmonic biosensor that can overcome this challenge using atomically thin two-dimensional (2D) phase change nanomaterial is developed. By precisely engineering the configuration with atomically thin materials, the phase singularity has been successfully achieved with a significantly enhanced lateral position shift effect. Based on our knowledge, it is the first experimental demonstration of a lateral position signal change > 340 μm at a sensing interface from all optical techniques. With this enhanced plasmonic effect, the detection limit has been experimentally demonstrated to be 10-15 mol L-1 for TNF-α cancer marker, which has been found in various human diseases including inflammatory diseases and different kinds of cancer. The as-reported novel integration of atomically thin Ge2Sb2Te5 (GST) with plasmonic substrate, which results in a phase singularity and thus a giant lateral position shift, enables the detection of cancer markers with low molecular weight at femtomolar level. These results will definitely hold promising potential in biomedical application and clinical diagnostics.

physics.app-ph

Terahertz Devices Using the Optical Activation of GeTe Phase Change Materials: Towards Fully Reconfigurable Functionalities

We are demonstrating the optical control of a specific state of the germanium telluride (GeTe) phase change material and its integration as control element for realizing extremely efficient optically reconfigurable THz devices. The excellent contrast of the material THz electrical properties in the two dissimilar states were used for optical-induced fast modulation of THz resonances of a hybrid metamaterial based of arrays of split ring resonator metallic structures integrating GeTe patterns. We experimentally confirm for the first time the feasibility to develop all dielectric (metal free) GeTe-based THz polarizers presenting a broadband response, a high extinction ratio when the GeTe is in the metal-like phase (up to 16.5 dB) and almost transparent when the material is in the amorphous phase. The presented highly functional approach based on non-volatile, optically controlled multi-operational THz devices integrating PCMs, is extremely stimulating for generating disruptive developments like field-programmable metasurfaces or all-dielectric coding metamaterials with multifunctional capabilities for THz waves manipulation.

physics.optics

Spatial beam self-cleaning in multimode lanthanum aluminum silicate glass fiber

We demonstrated that spatial Kerr beam self-cleaning can be obtained in a highly multimode multicomponent optical fiber based on lanthanum aluminum silicate oxide glasses (SiO2-Al2O3-La2O3), which was made by using the modified powder in tube technology (MIPT). We show how such fabrication method can provide interesting potentialities to design doped multimode optical fibers with homogeneous and quasi-parabolic refractive-index core profile for nonlinear optics applications.

physics.optics

A Test Resonator for Kagome Hollow-Core Photonic Crystal Fibers for Resonant Rotation Sensing

We build ring resonators to assess the potentialities of Kagome Hollow-Core Photonic Crystal Fibers for future applications to resonant rotation sensing. The large mode diameter of Kagome fibers permits to reduce the free space fiber-to-fiber coupling losses, leading to cavities with finesses of about 30 for a diameter equal to 15 cm. Resonance linewidths of 3.2~MHz with contrasts as large as 89\% are obtained. Comparison with 7-cell photonic band gap (PBG) fiber leads to better finesse and contrast with Kagome fiber. Resonators based on such fibers are compatible with the angular random walk required for medium to high performance rotation sensing. The small amount of light propagating in silica should also permit to further reduce the Kerr-induced non-reciprocity by at least three orders of magnitudes in 7-cell Kagome fiber compared with 7-cell PBG fiber.

physics.optics