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Georgy P Karev

Publications and source records attributed to Georgy P Karev.

2 recordsLinked to original sources

On the asymptotic behavior of the solutions to the replicator equation

Selection systems and the corresponding replicator equations model the evolution of replicators with a high level of abstraction. In this paper we apply novel methods of analysis of selection systems to the replicator equations. To be suitable for the suggested algorithm the interaction matrix of the replicator equation should be transformed; in particular the standard singular value decomposition allows us to rewrite the replicator equation in a convenient form. The original $n$-dimensional problem is reduced to the analysis of asymptotic behavior of the solutions to the so-called escort system, which in some important cases can be of significantly smaller dimension than the original system. The Newton diagram methods are applied to study the asymptotic behavior of the solutions to the escort system, when interaction matrix has rank 1 or 2. A general replicator equation with the interaction matrix of rank 1 is fully analyzed; the conditions are provided when the asymptotic state is a polymorphic equilibrium. As an example of the system with the interaction matrix of rank 2 we consider the problem from [Adams, M.R. and Sornborger, A.T., J Math Biol, 54:357-384, 2007], for which we show, for arbitrary dimension of the system and under some suitable conditions, that generically one globally stable equilibrium exits on the 1-skeleton of the simplex.

q-bio.PE↗

Population models with singular equilibrium

A class of models of biological population and communities with a singular equilibrium at the origin is analyzed; it is shown that these models can possess a dynamical regime of deterministic extinction, which is crucially important from the biological standpoint. This regime corresponds to the presence of a family of homoclinics to the origin, so-called elliptic sector. The complete analysis of possible topological structures in a neighborhood of the origin, as well as asymptotics to orbits tending to this point, is given. An algorithmic approach to analyze system behavior with parameter changes is presented. The developed methods and algorithm are applied to existing mathematical models of biological systems. In particular, we analyze a model of anticancer treatment with oncolytic viruses, a parasite-host interaction model, and a model of Chagas' disease.

q-bio.QM↗